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| Status |
Public on Jun 09, 2016 |
| Title |
Expression data from Sertoli cells treated with 0.1μM NP, 0.1mM MBP, 0.1μM NP+0.1mM MBP and solvent control |
| Platform organisms |
Rattus norvegicus; synthetic construct |
| Sample organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
Non-coding RNA profiling by array
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| Summary |
The combined effects of NP and MBP were much more toxic than NP or MBP exposed alone.
We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes and miRNAs after treated with 0.1μM NP, 0.1mM MBP, 0.1μM NP+0.1mM MBP and solvent control.
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| Overall design |
Rat Sertoli cell were selected from rat testis for RNA extraction and hybridization on Affymetrix microarrays. We sought to obtain the differentially expressed genes and miRNAs in 0.1μM NP, 0.1mM MBP, 0.1μM NP+0.1mM MBP and solvent control treated Sertoli cells, respectively.
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| Contributor(s) |
Li D, Hu Y |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Jun 08, 2016 |
| Last update date |
Jul 27, 2018 |
| Contact name |
Xiaoqin Yin |
| E-mail(s) |
[email protected]
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| Organization name |
School of medicine, Shanghai Jiao Tong University
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| Department |
Shanghai Children’s Hospital
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| Lab |
Department of endocrinology
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| Street address |
No. 355 Luding Road, Shanghai 200062, P.R.China.
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| City |
Shanghai |
| State/province |
Shanghai |
| ZIP/Postal code |
200062 |
| Country |
China |
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| Platforms (2) |
| GPL6247 |
[RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [transcript (gene) version] |
| GPL16384 |
[miRNA-3] Affymetrix Multispecies miRNA-3 Array |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA324772 |
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