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Series GSE89785 Query DataSets for GSE89785
Status Public on Nov 11, 2019
Title Transcriptional profile Lactobacillus plantarum WCFS1 : Resveratrol treated cells
Organism Lactiplantibacillus plantarum
Experiment type Expression profiling by array
Summary Whole genome transcriptional profiling was used to characterize the response of Lactobacillus plantarum WCFS1 human isolate during challenge with resveratrol. Twelve independent experiments were performed and mixed at random in groups of four for total of three RNA samples. The transcriptional profile reveals a large reshape of nitrogen metabolism whic affects, among others, the pyridine and purine metabolisms as well as the metabolism of aminoacids related to thiol-specific oxidative stress response in this microorganism. Genes involved in the general stress response and carbon metabolism were also affected. A distinctive feature of the response to resveratrol identified in the transcriptomic analysis was a marked modulation of genes coding for certain ABC-type transporters.
 
Overall design Biological triplicates: untreated cells: Control vs. Resveratrol treated cells: Experimental
 
Contributor(s) Reverón I, Plaza L, de las Rivas B, Muñoz R, de Felipe FL
Citation(s) 29573169
Submission date Nov 12, 2016
Last update date Feb 10, 2020
Contact name Felix Lopez de Felipe
E-mail(s) [email protected]
Organization name ICTAN-CSIC
Street address Jose Antonio Novais
City Madrid
ZIP/Postal code 28040
Country Spain
 
Platforms (1)
GPL22663 Agilent-026636 Lactobacillus plantarum Prueba Lp IFI 021109
Samples (3)
GSM2388846 Resveratrol 10 min replicate 1
GSM2388847 Resveratrol 10 min replicate 2
GSM2388848 Resveratrol 10 min replicate 3
Relations
BioProject PRJNA353281

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE89785_GEO_Resveratrol_vs_Control_GE_RESULTS_Targets.txt.gz 1.1 Mb (ftp)(http) TXT
GSE89785_GEO_Resveratrol_vs_Control_NORMDATA_Targets.txt.gz 735.3 Kb (ftp)(http) TXT
GSE89785_GEO_Resveratrol_vs_Control_RAWDATA_Targets.txt.gz 713.7 Kb (ftp)(http) TXT
GSE89785_RAW.tar 13.9 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table
Processed data provided as supplementary file
Processed data are available on Series record

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