|
| Status |
Public on Feb 06, 2017 |
| Title |
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL [RNA-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA-seq was performed in human Ph+ pre-B ALL cells that harbor a deletion of the Ikaros DNA binding domain (Ik6) after doxycycline induction of exogenous expression of wild-type Ikaros (Ik1) or control empty vector over 0, 12, 24 and 48 hours. Biological replicates (n=2) using independent cultures and inductions were performed.
|
| |
|
| Overall design |
RNA-Seq from human BCR-ABL+ pre-B ALL xenograft cell-line PDX2 following 24 h of DOX induction of IK1 or empty vector controls
|
| |
|
| Contributor(s) |
Frietze S, Schjerven H |
| Citation(s) |
28190001 |
| |
| Submission date |
Nov 29, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Seth Frietze |
| E-mail(s) |
[email protected]
|
| Phone |
8026560569
|
| Organization name |
University of Vermont
|
| Department |
BHSC
|
| Street address |
106 Carrigan Drive
|
| City |
Burlington |
| State/province |
VT |
| ZIP/Postal code |
05405 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (16)
|
|
| This SubSeries is part of SuperSeries: |
| GSE90670 |
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL |
|
| Relations |
| BioProject |
PRJNA355295 |
| SRA |
SRP094073 |
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