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| Status |
Public on May 25, 2019 |
| Title |
Expression data from B cells expressing human AIRE |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Aire in medullary thymic epithelial cells plays an essential role in the establishment of self-tolerance through expression of broad arrays of tissue-restricted antigens. We asked what would happen if human AIRE is additively expressed in antigen-presenting cells in the thymus and periphery.
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| Overall design |
We established a human AIRE-transgenic mouse line on NOD-background using MHC class II promoter and hybridization was performed on Affymetrix microarrays.
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| Contributor(s) |
Matsumoto M, Nishijima H |
| Citation(s) |
28931462 |
| |
| Submission date |
May 26, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Mitsuru Matsumoto |
| E-mail(s) |
[email protected]
|
| Organization name |
Institute for Enzyme Research, Tokushima University
|
| Department |
Division of Molecular Immunology
|
| Street address |
3-18-15 Kuramoto
|
| City |
Tokushima |
| ZIP/Postal code |
770-8503 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA388209 |
