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Genomind Pharmacogenetic Report
Clinical Genetic Test
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offered by
Genomind, Inc.
View lab's test page
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GTR Test Accession: Help GTR000523653.14
NYS CLEP
CAP
PSYCHIATRICNERVOUS SYSTEMINHERITED DISEASE ... View more
Last updated in GTR: 2024-10-24
View version history
Last annual review date for the lab: 2024-10-24 LinkOut
At a Glance
Test purpose: Help
Drug Response; Therapeutic management
Conditions (14): Help
Major depressive disorder; Anxiety; Attention deficit hyperactivity disorder more...
Genes (27): Help
ABCB1 (7q21.12); ABCG2 (4q22.1); ADRA2A (10q25.2); ANK3 (10q21.2); BDNF (11p14.1) more...
Methods (1): Help
Molecular Genetics - Targeted variant analysis: Quantitative PCR (qPCR)
Target population: Help
Psychiatric population Polypharmacy
Clinical validity: Help
In the field of pharmacogenetics, one aspect of clinical validity …
Clinical utility: Help
Guidance for management; Guidance for selecting a drug therapy and/or dose; Healthcare Cost Savings; ...
Ordering Information
Offered by: Help
Genomind, Inc.
View lab's website
View lab's test page
Test short name: Help
Genomind PGx
Specimen Source: Help
Who can order: Help
  • Health Care Provider
  • Licensed Physician
  • Nurse Practitioner
  • Physician Assistant
Test Order Code: Help
Genomind Pharmacogenetic Report
View other test codes
CPT codes: Help
**AMA CPT codes notice

Copyright: 2023 American Medical Association. All rights reserved.

Contact Policy: Help
Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
How to Order: Help
Treating clinicians with prescribing rights may order the test directly from www.genomind.com, by phone at 1-877-895-8658, or by emailing [email protected].
Order URL
Test service: Help
Clinical Testing/Confirmation of Mutations Identified Previously
    Comment: Pharmacogenetic testing
Custom Deletion/Duplication Testing
Result interpretation
Test development: Help
Test developed by laboratory (no manufacturer test name)
Informed consent required: Help
Yes
Test strategy: Help
Testing of all 26 genes on the panel is done simultaneously. If one gene fails to produce results reflex testing is performed where applicable and provider is notified if this will delay the turn-around time of the test. If additional testing cannot be performed due to poor sample quality or … View more
Pre-test genetic counseling required: Help
No
Post-test genetic counseling required: Help
No
Recommended fields not provided:
Lab contact for this test
Conditions Help
Total conditions: 14
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 27
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 1
Method Category Help
Test method Help
Instrument
Targeted variant analysis
Quantitative PCR (qPCR)
QuantStudio 12k Flex Real Time Instrument
QuantStudio 7K FLEX Real Time Instrument
Clinical Information
Test purpose: Help
Drug Response; Therapeutic management
Clinical validity: Help
Clinical utility: Help
Guidance for management
View citations (3)
  • Brennan FX, Gardner KR, Lombard J, Perlis RH, et al. A Naturalistic Study of the Effectiveness of Pharmacogenetic Testing to Guide Treatment in Psychiatric Patients With Mood and Anxiety Disorders. Prim Care Companion CNS Disord. 2015; 17 (2). Gardner KR, Brennan FX, Scott R & Lombard J.The potential utility of pharmacogenetic testing in psychiatry. Psychiatry J. 2014;2014:730956. Fagerness J, Fonseca E, Hess GP, Scott R, Gardner KR, et al. Pharmacogenetic-guided psychiatric intervention associated with increased adherence and cost savings. Am J Manag Care. 2014 May;20(5):e146-56.
  • https://www.personalizedmedpsych.com/article/S2468-1717(17)30027-3/fulltext
  • https://www.personalizedmedpsych.com/article/S2468-1717(17)30027-3/fulltext

Guidance for selecting a drug therapy and/or dose
View citations (5)

Healthcare Cost Savings
View citations (2)

Lifestyle planning
View citations (2)

Target population: Help
Psychiatric population Polypharmacy
View citations (2)
  • Brennan FX, Gardner KR, Lombard J, Perlis RH, Fava M, Harris HW, Scott R. A Naturalistic Study of the Effectiveness of Pharmacogenetic Testing to Guide Treatment in Psychiatric Patients With Mood and Anxiety Disorders. Prim Care Companion CNS Disord. 2015;17(2). doi:10.4088/PCC.14m01717. Epub 2015 Apr 16. PMID: 26445691.
  • Perlis RH, Mehta R, Edwards AM, Tiwari A, Imbens GW. Pharmacogenetic testing among patients with mood and anxiety disorders is associated with decreased utilization and cost: A propensity-score matched study. Depress Anxiety. 2018;35(10):946-952. doi:10.1002/da.22742. Epub 2018 May 07. PMID: 29734486.
Variant Interpretation:
What is the protocol for interpreting a variation as a VUS? Help
When a rare variation not defined within our proprietary algorithm occurs, a dedicated scientific team performs a thorough review of available published literature.

Are family members with defined clinical status recruited to assess significance of VUS without charge? Help
No.

Will the lab re-contact the ordering physician if variant interpretation changes? Help
No.
Recommended fields not provided:
Is research allowed on the sample after clinical testing is complete?, Sample negative report, Sample positive report
Technical Information
Test Platform:
Other
Test Confirmation: Help
Testing is performed in duplicate
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
Analytical accuracy and reproducibility is greater than 99% for the Genomind Pharmacogenetic assay.
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
Yes

Method used for proficiency testing: Help
Formal PT program

PT Provider: Help
College of American Pathologists, CAP

CAP Testing Information Help
Pharmacogenetics; CYP2C19; PGX
VUS:
Software used to interpret novel variations Help
None

Laboratory's policy on reporting novel variations Help
The novel result is listed as indeterminate on the results report, and an email communication and/or a phone consultation is utilized to relay results.
Recommended fields not provided:
Assay limitations, Description of internal test validation method, Citations for Analytical validity, Description of PT method
Regulatory Approval
FDA Review: Help
Category: FDA exercises enforcement discretion
NYS CLEP Approval: Help
Number: 9035
Status: Approved
Additional Information

IMPORTANT NOTE: NIH does not independently verify information submitted to GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.