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Lutheran (Lua/Lub) Genotyping
Clinical Genetic Test
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offered by
Versiti Diagnostic Laboratories
View lab's test page
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GTR Test Accession: Help GTR000525832.4
NYS CLEP
INHERITED DISEASEHEMATOLOGY
Last updated in GTR: 2022-10-25
View version history
Last annual review date for the lab: 2024-11-15 LinkOut
At a Glance
Test purpose: Help
Mutation Confirmation
Conditions (1): Help
Beta-thalassemia-X-linked thrombocytopenia syndrome
Genes (1): Help
BCAM (19q13.32)
Methods (1): Help
Molecular Genetics - Sequence analysis of the entire coding region: PCR with allele specific hybridization
Target population: Help
Not provided
Clinical validity: Help
Not provided
Clinical utility: Help
Not provided
Ordering Information
Offered by: Help
Versiti Diagnostic Laboratories
View lab's website
View lab's test page
Specimen Source: Help
Who can order: Help
  • Genetic Counselor
  • Health Care Provider
  • Licensed Physician
  • Nurse Practitioner
Test Order Code: Help
3868
View other test codes
CPT codes: Help
**AMA CPT codes notice

Copyright: 2023 American Medical Association. All rights reserved.

Contact Policy: Help
Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
How to Order: Help
Order URL
Test service: Help
Genetic counseling
Identity Testing
Test development: Help
Test developed by laboratory (no manufacturer test name)
Informed consent required: Help
Based on applicable state law
Pre-test genetic counseling required: Help
Decline to answer
Post-test genetic counseling required: Help
Decline to answer
Recommended fields not provided:
Lab contact for this test, Test strategy
Conditions Help
Total conditions: 1
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 1
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 1
Method Category Help
Test method Help
Instrument *
Sequence analysis of the entire coding region
PCR with allele specific hybridization
* Instrument: Not provided
Clinical Information
Test purpose: Help
Mutation Confirmation
Recommended fields not provided:
Clinical validity, Clinical utility, Target population, What is the protocol for interpreting a variation as a VUS?, Are family members with defined clinical status recruited to assess significance of VUS without charge?, Will the lab re-contact the ordering physician if variant interpretation changes?, Is research allowed on the sample after clinical testing is complete?, Sample negative report, Sample positive report
Technical Information
Test Comments: Help
The Dombrock (DO) and Lutheran (LU) blood group systems are each characterized by two main antigenic variants: Doa and Dob are encoded by the DO1 and DO2 alleles and Lua and Lub are encoded by the LU1 and LU2 alleles. The Kell blood group (KEL) is comprised of several antigenic … View more
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
Assay sensitivity and specificity is >99%.
Assay limitations: Help
Rare mutations resulting in loss of expression of the Lua and Lub antigens will not be detected by this assay.
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
No
Recommended fields not provided:
Test Confirmation, Citations to support assay limitations, Description of internal test validation method, Citations for Analytical validity, PT Provider, Description of PT method, Major CAP category, CAP category, CAP test list
Regulatory Approval
FDA Review: Help
Category: FDA exercises enforcement discretion
NYS CLEP Approval: Help
Number: 10056
Status: Approved
Additional Information

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