GTR Test Accession:
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GTR000556787.2
Last updated in GTR:
2019-05-22
View version history
GTR000556787.2,
last updated:
2019-05-22
GTR000556787.1,
registered in GTR:
2018-05-25
Last annual review date for the lab: 2024-03-22
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At a Glance
Test purpose:
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Drug Response
Conditions (1):
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Olanzapine response
Genes (2):
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ANKK1 (11q23.2);
CYP1A2 (15q24.1)
Methods (1):
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Molecular Genetics - Targeted variant analysis: SNP Detection
Target population: Help
Not provided
Clinical validity:
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Not provided
Clinical utility:
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Not provided
Ordering Information
Offered by:
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Specimen Source:
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- Buccal swab
- Isolated DNA
- Peripheral (whole) blood
- Saliva
Who can order: Help
- In-State Patients
Contact Policy:
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Post-test email/phone consultation regarding genetic test results and interpretation is provided to patients/families.
How to Order:
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Please send us an email at [email protected] or call us at +91-95432-89999 to learn about test requirements and ordering procedure. We perform tests using saliva/blood sample.
Order URL
Order URL
Test service:
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Clinical Testing/Confirmation of Mutations Identified Previously
Informed consent required:
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Yes
Pre-test genetic counseling required:
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No
Post-test genetic counseling required:
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Yes
Recommended fields not provided:
Test Order Code,
Lab contact for this test,
Test strategy,
Test development
Conditions
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Total conditions: 1
Condition/Phenotype | Identifier |
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Test Targets
Genes
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Total genes: 2
Gene | Associated Condition | Germline or Somatic | Allele (Lab-provided) | Variant in NCBI |
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Methodology
Total methods: 1
Method Category
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Test method
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Instrument *
Targeted variant analysis
SNP Detection
* Instrument: Not provided
Clinical Information
Test purpose:
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Drug Response
Variant Interpretation:
What is the protocol for interpreting a variation as a VUS?
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We follow standard guidelines as per different organizations like CPIC and ACMG.
We follow standard guidelines as per different organizations like CPIC and ACMG.
Will the lab re-contact the ordering physician if variant interpretation changes?
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.
.
Recommended fields not provided:
Clinical validity,
Clinical utility,
Target population,
Are family members with defined clinical status recruited to assess significance of VUS without charge?,
Is research allowed on the sample after clinical testing is complete?,
Sample negative report,
Sample positive report
Technical Information
Availability:
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Tests performed
Entire test performed in-house
Entire test performed in-house
Analytical Validity:
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The analytical sensitivity of the test is >99%
Proficiency testing (PT):
Is proficiency testing performed for this test?
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No
No
VUS:
Software used to interpret novel variations
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Proprietary internal software
Proprietary internal software
Recommended fields not provided:
Test Confirmation,
Assay limitations,
Description of internal test validation method,
Citations for Analytical validity,
PT Provider,
Description of PT method,
Major CAP category, CAP category, CAP test list
Regulatory Approval
FDA Review:
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Not provided
Additional Information
Reviews:
Clinical resources:
Consumer resources:
IMPORTANT NOTE:
NIH does not independently verify information submitted to GTR; it relies on submitters to provide information that is accurate and not misleading.
NIH makes no endorsements of tests or laboratories listed in GTR. GTR is not a substitute for medical advice.
Patients and consumers
with specific questions about a genetic test should contact a health care provider or a genetics professional.