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Vestibular saccular degeneration

MedGen UID:
1374589
•Concept ID:
C4476903
•
Disease or Syndrome
HPO: HP:0031000

Definition

Deterioration or loss of the tissues of the saccule of the vestibule. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVestibular saccular degeneration

Recent clinical studies

Etiology

Peripheral Vestibular Organ Degeneration After Temporal Bone Fracture: A Human Otopathology Study.
Knoll RM, Ishai R, Lubner RJ, Trakimas DR, Brodsky JR, Jung DH, Rauch SD, Nadol JB Jr,, Remenschneider AK, Kozin ED
Laryngoscope 2020 Mar;130(3):752-760. Epub 2019 May 10 doi: 10.1002/lary.28010. PMID: 31074866
Evaluation of the utricular and saccular function using oVEMPs and cVEMPs in BPPV patients.
Xu H, Liang FY, Chen L, Song XC, Tong MC, Thong JF, Zhang QQ, Sun Y
J Otolaryngol Head Neck Surg 2016 Feb 9;45:12. doi: 10.1186/s40463-016-0125-7. PMID: 26857819Free PMC Article
Transient evoked otoacoustic emissions in vestibular neuritis.
Gouveris H, Victor A, Mann W
Ann Otol Rhinol Laryngol 2006 Dec;115(12):908-11. doi: 10.1177/000348940611501209. PMID: 17214265

Diagnosis

Evaluation of retrootolithic function using galvanic vestibular-evoked myogenic potentials in patients with benign paroxysmal positional vertigo.
Chang CM, Lo WC, Young YH, Liao LJ, Wu PH, Cheng PC, Cheng PW
Eur Arch Otorhinolaryngol 2022 Jul;279(7):3415-3423. Epub 2021 Sep 25 doi: 10.1007/s00405-021-07094-9. PMID: 34562111
Evaluation of the utricular and saccular function using oVEMPs and cVEMPs in BPPV patients.
Xu H, Liang FY, Chen L, Song XC, Tong MC, Thong JF, Zhang QQ, Sun Y
J Otolaryngol Head Neck Surg 2016 Feb 9;45:12. doi: 10.1186/s40463-016-0125-7. PMID: 26857819Free PMC Article
Vestibular evoked myogenic potentials in patients with BPPV.
Korres S, Gkoritsa E, Giannakakou-Razelou D, Yiotakis I, Riga M, Nikolpoulos TP
Med Sci Monit 2011 Jan;17(1):CR42-47. doi: 10.12659/msm.881328. PMID: 21169909Free PMC Article
Pathology of benign paroxysmal positional vertigo revisited.
Gacek RR
Ann Otol Rhinol Laryngol 2003 Jul;112(7):574-82. doi: 10.1177/000348940311200702. PMID: 12903676
The vestibular system in the elderly.
Babin RW, Harker LA
Otolaryngol Clin North Am 1982 May;15(2):387-93. PMID: 6979732

Prognosis

Evaluation of the utricular and saccular function using oVEMPs and cVEMPs in BPPV patients.
Xu H, Liang FY, Chen L, Song XC, Tong MC, Thong JF, Zhang QQ, Sun Y
J Otolaryngol Head Neck Surg 2016 Feb 9;45:12. doi: 10.1186/s40463-016-0125-7. PMID: 26857819Free PMC Article
Otopathology in idiopathic Dandy's syndrome.
Viana LM, Salviz M, Rauch SD, Nadol JB
Otol Neurotol 2013 Aug;34(6):1099-103. doi: 10.1097/MAO.0b013e3182814e74. PMID: 23542133Free PMC Article
Mutations in Cdh23 cause nonsyndromic hearing loss in waltzer mice.
Wilson SM, Householder DB, Coppola V, Tessarollo L, Fritzsch B, Lee EC, Goss D, Carlson GA, Copeland NG, Jenkins NA
Genomics 2001 Jun 1;74(2):228-33. doi: 10.1006/geno.2001.6554. PMID: 11386759
Internal auditory artery infarction: clinicopathologic correlation.
Kim JS, Lopez I, DiPatre PL, Liu F, Ishiyama A, Baloh RW
Neurology 1999 Jan 1;52(1):40-4. doi: 10.1212/wnl.52.1.40. PMID: 9921846

Clinical prediction guides

Evaluation of the utricular and saccular function using oVEMPs and cVEMPs in BPPV patients.
Xu H, Liang FY, Chen L, Song XC, Tong MC, Thong JF, Zhang QQ, Sun Y
J Otolaryngol Head Neck Surg 2016 Feb 9;45:12. doi: 10.1186/s40463-016-0125-7. PMID: 26857819Free PMC Article
Pathology of benign paroxysmal positional vertigo revisited.
Gacek RR
Ann Otol Rhinol Laryngol 2003 Jul;112(7):574-82. doi: 10.1177/000348940311200702. PMID: 12903676
Mutations in Cdh23 cause nonsyndromic hearing loss in waltzer mice.
Wilson SM, Householder DB, Coppola V, Tessarollo L, Fritzsch B, Lee EC, Goss D, Carlson GA, Copeland NG, Jenkins NA
Genomics 2001 Jun 1;74(2):228-33. doi: 10.1006/geno.2001.6554. PMID: 11386759
Temporal bone histopathology 14 years after cytomegalic inclusion disease: a case study.
Rarey KE, Davis LE
Laryngoscope 1993 Aug;103(8):904-9. doi: 10.1288/00005537-199308000-00012. PMID: 8395628
Histopathological observations of ultrasound treatment in Ménière's disease: case report.
Bertrand RA, Perron D
J Otolaryngol 1980 Apr;9(2):113-20. PMID: 6103074

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