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Benign neoplasm of hard palate

MedGen UID:
138020
•Concept ID:
C0345552
•
Neoplastic Process
Synonyms: Benign Hard Palate Neoplasm; benign hard palate neoplasm; Benign Hard Palate Tumor; benign hard palate tumor; benign hard palate tumour; Benign Neoplasm of Hard Palate; benign neoplasm of hard palate; Benign Neoplasm of the Hard Palate; benign neoplasm of the hard palate; Benign tumor of hard palate; Benign Tumor of Hard Palate; benign tumor of hard palate; Benign Tumor of the Hard Palate; benign tumor of the hard palate; benign tumour of hard palate; benign tumour of the hard palate; hard palate benign neoplasm
SNOMED CT: Benign neoplasm of hard palate (92129006); Benign tumor of hard palate (92129006)
 
Monarch Initiative: MONDO:0021518

Definition

A neoplasm that arises from the hard palate and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of hard palate

Professional guidelines

PubMed

Psychosocial Oncology: Optimizing Outcomes through Interdisciplinary Care in Head and Neck Oncology.
Henry M
Curr Oncol 2023 Jul 19;30(7):6859-6861. doi: 10.3390/curroncol30070501. PMID: 37504361Free PMC Article
Recurrence of premalignant oral cavity and oropharynx lesions after pulsed diode laser treatment.
Sagalow ES, Kumar AT, Banoub RG, Xiao KB, Zhan T, Luginbuhl A, Curry JM
Am J Otolaryngol 2022 Sep-Oct;43(5):103556. Epub 2022 Aug 3 doi: 10.1016/j.amjoto.2022.103556. PMID: 35952526
Management of NK/T-Cell Lymphoma, Nasal Type.
Allen PB, Lechowicz MJ
J Oncol Pract 2019 Oct;15(10):513-520. doi: 10.1200/JOP.18.00719. PMID: 31600461Free PMC Article

Recent clinical studies

Etiology

Oral Mucosal Melanoma.
Nisi M, Izzetti R, Gennai S, Pucci A, Lenzi C, Graziani F
J Craniofac Surg 2022 May 1;33(3):830-834. Epub 2021 Jul 30 doi: 10.1097/SCS.0000000000008054. PMID: 34334749
Perineural Invasion and Perineural Tumor Spread in Head and Neck Cancer.
Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Melanotic neuroectodermal tumor of infancy of the maxilla: a case report with review of literature.
Rustagi A, Roychoudhury A, Karak AK
J Oral Maxillofac Surg 2011 Apr;69(4):1120-4. doi: 10.1016/j.joms.2010.01.017. PMID: 20619949
Calcifications in clear cell mucoepidermoid carcinomas.
Yang S, Chen X
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010 Feb;109(2):274-5. Epub 2009 Oct 31 doi: 10.1016/j.tripleo.2009.08.012. PMID: 19880334
Nomenclature and classification of potentially malignant disorders of the oral mucosa.
Warnakulasuriya S, Johnson NW, van der Waal I
J Oral Pathol Med 2007 Nov;36(10):575-80. doi: 10.1111/j.1600-0714.2007.00582.x. PMID: 17944749

Diagnosis

Oral Malignant Melanoma: A Case Report.
Sen S, Sen S, Kumari MG, Khan S, Singh S
Prague Med Rep 2021;122(3):222-227. doi: 10.14712/23362936.2021.20. PMID: 34606435
Pleomorphic adenoma of hard palate: a case report.
Yousra Z, Saliha C
Pan Afr Med J 2021;38:146. Epub 2021 Feb 9 doi: 10.11604/pamj.2021.38.146.26508. PMID: 33912316Free PMC Article
Primary malignant melanoma.
Mısır AF, Durmuşlar MC, Zerener T, Gün BD
Saudi Med J 2016 Apr;37(4):446-9. doi: 10.15537/smj.2016.4.15017. PMID: 27052289Free PMC Article
CT and MR imaging findings of palatal tumors.
Kato H, Kanematsu M, Makita H, Kato K, Hatakeyama D, Shibata T, Mizuta K, Aoki M
Eur J Radiol 2014 Mar;83(3):e137-46. Epub 2013 Dec 12 doi: 10.1016/j.ejrad.2013.11.028. PMID: 24377674
Nomenclature and classification of potentially malignant disorders of the oral mucosa.
Warnakulasuriya S, Johnson NW, van der Waal I
J Oral Pathol Med 2007 Nov;36(10):575-80. doi: 10.1111/j.1600-0714.2007.00582.x. PMID: 17944749

Therapy

Ulcerated Infantile Hemangioma of the Hard Palate: Diagnostic Treatment With Oral Propranolol.
Ishikawa K, Fujita M, Takeda T, Mitamura S, Nishio T, Funayama E, Hayashi T, Osawa M, Maeda T, Yamamoto Y, Sasaki S
J Craniofac Surg 2020 Sep;31(6):e600-e602. doi: 10.1097/SCS.0000000000006666. PMID: 32649551
A Large Gray-Blue Macule on the Hard Palate as an Adverse Effect of Imatinib.
Lueken N, Kaune KM, Zutt M
Dtsch Arztebl Int 2019 Feb 8;116(6):95. doi: 10.3238/arztebl.2019.0095. PMID: 30892185Free PMC Article
Pigmented oral mucosa due to quinacrine.
López-Jornet P, Pons-Fuster A
N Y State Dent J 2011 Nov;77(6):49-51. PMID: 22338819
Elimination of palatal fistula after the maxillary swing procedure.
Ng RW, Wei WI
Head Neck 2005 Jul;27(7):608-12. doi: 10.1002/hed.20220. PMID: 15920745
Nicotine stomatitis and its relation to carcinoma of the hard palate in reverse smokers of chuttas.
Ramulu C, Raju MV, Venkatarathnam G, Reddy CR
J Dent Res 1973 Jul-Aug;52(4):711-8. doi: 10.1177/00220345730520041201. PMID: 4515851

Prognosis

Oral Mucosal Melanoma.
Nisi M, Izzetti R, Gennai S, Pucci A, Lenzi C, Graziani F
J Craniofac Surg 2022 May 1;33(3):830-834. Epub 2021 Jul 30 doi: 10.1097/SCS.0000000000008054. PMID: 34334749
Oral Malignant Melanoma: A Case Report.
Sen S, Sen S, Kumari MG, Khan S, Singh S
Prague Med Rep 2021;122(3):222-227. doi: 10.14712/23362936.2021.20. PMID: 34606435
Sialadenoma Papilliferum.
Hsieh MS, Bishop JA, Yu Fong Chang J
Surg Pathol Clin 2021 Mar;14(1):43-51. Epub 2021 Jan 5 doi: 10.1016/j.path.2020.09.006. PMID: 33526222
Perineural Invasion and Perineural Tumor Spread in Head and Neck Cancer.
Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Melanotic neuroectodermal tumor of infancy of the maxilla: a case report with review of literature.
Rustagi A, Roychoudhury A, Karak AK
J Oral Maxillofac Surg 2011 Apr;69(4):1120-4. doi: 10.1016/j.joms.2010.01.017. PMID: 20619949

Clinical prediction guides

Nodal Metastasis in Surgically Treated Oral Cavity Squamous Cell Carcinoma.
Carey RM, Anagnos VJ, Prasad A, Sangal NR, Rajasekaran K, Shanti RM, Cannady SB, Newman JG, Brant JA, Brody RM
ORL J Otorhinolaryngol Relat Spec 2023;85(6):348-359. Epub 2023 Nov 15 doi: 10.1159/000534491. PMID: 37967536Free PMC Article
A short review on DNA damage and repair effects in lip cancer.
Toprani SM, Kelkar Mane V
Hematol Oncol Stem Cell Ther 2021 Dec;14(4):267-274. Epub 2021 Feb 17 doi: 10.1016/j.hemonc.2021.01.007. PMID: 33626329
A Case of Fibrolipoma of the Hard Palate.
Hayashi K, Yamada S, Onda T, Shibahara T
Bull Tokyo Dent Coll 2020 Mar 12;61(1):53-60. Epub 2020 Feb 20 doi: 10.2209/tdcpublication.2019-0010. PMID: 32074588
Hard Palate Melanoma: A Population-based Analysis of Epidemiology and Survival Outcomes.
Oranges CM, Sisti G, Nasioudis D, Tremp M, DI Summa PG, Kalbermatten DF, Largo RD, Schaefer DJ
Anticancer Res 2018 Oct;38(10):5811-5817. doi: 10.21873/anticanres.12921. PMID: 30275204
Maxillary ameloblastomas: a review of the literature and of a 15-year database.
Zwahlen RA, Grätz KW
J Craniomaxillofac Surg 2002 Oct;30(5):273-9. doi: 10.1016/s1010-5182(02)90317-3. PMID: 12377199

Recent systematic reviews

Oral Mucosal Melanoma.
Nisi M, Izzetti R, Gennai S, Pucci A, Lenzi C, Graziani F
J Craniofac Surg 2022 May 1;33(3):830-834. Epub 2021 Jul 30 doi: 10.1097/SCS.0000000000008054. PMID: 34334749
Systematic Review of Clinical and Radiographic Signs of Pediatric Pleomorphic Adenoma of Minor Salivary Glands.
Alsufyani NA, Altowaijri AA, Alshehri BM, Alsadhan MS
J Contemp Dent Pract 2021 Sep 1;22(9):1063-1068. PMID: 35000954
Systematic review and meta-analysis of cervical metastases in oral maxillary squamous cell carcinoma.
Chia C, Key S, Hasan Z, Virk S, Riffat F
Cancer Rep (Hoboken) 2021 Dec;4(6):e1410. Epub 2021 May 8 doi: 10.1002/cnr2.1410. PMID: 33963809Free PMC Article
Canalicular adenoma: A systematic review.
Peraza AJ, Wright J, Gómez R
J Craniomaxillofac Surg 2017 Oct;45(10):1754-1758. Epub 2017 Aug 3 doi: 10.1016/j.jcms.2017.07.020. PMID: 28890252
Cervical metastases of oral maxillary squamous cell carcinoma: A systematic review and meta-analysis.
Zhang WB, Peng X
Head Neck 2016 Apr;38 Suppl 1:E2335-42. Epub 2016 Feb 18 doi: 10.1002/hed.24274. PMID: 26890607

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