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Liver angiosarcoma

MedGen UID:
138027
•Concept ID:
C0345907
•
Neoplastic Process
Synonyms: angiosarcoma (disease) of liver; Angiosarcoma of liver; Angiosarcoma of Liver; angiosarcoma of liver; Angiosarcoma of the Liver; angiosarcoma of the liver; Hemangiosarcoma of Liver; hemangiosarcoma of liver; Hemangiosarcoma of the Liver; hemangiosarcoma of the liver; Hepatic Angiosarcoma; hepatic angiosarcoma; Hepatic Hemangiosarcoma; hepatic hemangiosarcoma; Lias; Liver Angiosarcoma; liver angiosarcoma; liver angiosarcoma (disease); Liver Hemangiosarcoma; liver hemangiosarcoma; Primary Angiosarcoma of Liver; primary angiosarcoma of liver; Primary Angiosarcoma of the Liver; primary angiosarcoma of the liver
SNOMED CT: Angiosarcoma of liver (109844006)
 
Monarch Initiative: MONDO:0002387

Definition

A malignant vascular neoplasm arising from the liver. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLiver angiosarcoma

Professional guidelines

PubMed

Management Strategies and Outcomes in Primary Liver Angiosarcoma.
Ramakrishnan N, Mokhtari R, Charville GW, Bui N, Ganjoo K
Am J Clin Oncol 2023 Oct 1;46(10):439-444. Epub 2023 Aug 15 doi: 10.1097/COC.0000000000001032. PMID: 37580871Free PMC Article
EASL clinical practice guidelines for the management of occupational liver diseases.
Colombo M
Liver Int 2020 Feb;40 Suppl 1:136-141. doi: 10.1111/liv.14349. PMID: 32077606
A pooled analysis of treatment and prognosis of hepatic angiosarcoma in adults.
Li DB, Si XY, Wan T, Zhou YM
Hepatobiliary Pancreat Dis Int 2018 Jun;17(3):198-203. Epub 2018 Apr 23 doi: 10.1016/j.hbpd.2018.04.005. PMID: 29724676

Recent clinical studies

Etiology

Management Strategies and Outcomes in Primary Liver Angiosarcoma.
Ramakrishnan N, Mokhtari R, Charville GW, Bui N, Ganjoo K
Am J Clin Oncol 2023 Oct 1;46(10):439-444. Epub 2023 Aug 15 doi: 10.1097/COC.0000000000001032. PMID: 37580871Free PMC Article
Mortality from liver angiosarcoma, hepatocellular carcinoma, and cirrhosis among vinyl chloride workers.
Fedeli U, Girardi P, Gardiman G, Zara D, Scoizzato L, Ballarin MN, Baccini M, Pirastu R, Comba P, Mastrangelo G
Am J Ind Med 2019 Jan;62(1):14-20. Epub 2018 Nov 25 doi: 10.1002/ajim.22922. PMID: 30474170
A pooled analysis of treatment and prognosis of hepatic angiosarcoma in adults.
Li DB, Si XY, Wan T, Zhou YM
Hepatobiliary Pancreat Dis Int 2018 Jun;17(3):198-203. Epub 2018 Apr 23 doi: 10.1016/j.hbpd.2018.04.005. PMID: 29724676
Unusual Indications for a Liver Transplant: A Single-Center Experience.
Akdur A, Kirnap M, Ayvazoglu Soy EH, Ozcay F, Moray G, Arslan G, Haberal M
Exp Clin Transplant 2017 Feb;15(Suppl 1):128-132. doi: 10.6002/ect.mesot2016.P11. PMID: 28260452
Toxicity of vinyl chloride and poly(vinyl chloride): a critical review.
Wagoner JK
Environ Health Perspect 1983 Oct;52:61-6. doi: 10.1289/ehp.835261. PMID: 6360677Free PMC Article

Diagnosis

Management Strategies and Outcomes in Primary Liver Angiosarcoma.
Ramakrishnan N, Mokhtari R, Charville GW, Bui N, Ganjoo K
Am J Clin Oncol 2023 Oct 1;46(10):439-444. Epub 2023 Aug 15 doi: 10.1097/COC.0000000000001032. PMID: 37580871Free PMC Article
A Novel Entity Among Vascular Liver Tumors: The First Reported Liver Transplantation. Is It Feasible?
Renzo CD, D'Amico F, Finotti M, Vitale A, Mescoli C, Cillo U
Transplant Proc 2021 Jun;53(5):1690-1693. Epub 2021 May 14 doi: 10.1016/j.transproceed.2021.02.027. PMID: 34001349
EASL clinical practice guidelines for the management of occupational liver diseases.
Colombo M
Liver Int 2020 Feb;40 Suppl 1:136-141. doi: 10.1111/liv.14349. PMID: 32077606
Hepatic Angiosarcoma with Kasabach-Merritt Phenomenon: A Case Report and Review of the Literature.
Fujii F, Kimura T, Tanaka N, Kubota D, Sugiura A, Umemura T, Wada S, Tanaka E
Ann Hepatol 2018 July - August ,;17(4):655-660. doi: 10.5604/01.3001.0012.0949. PMID: 29893706
Unusual Indications for a Liver Transplant: A Single-Center Experience.
Akdur A, Kirnap M, Ayvazoglu Soy EH, Ozcay F, Moray G, Arslan G, Haberal M
Exp Clin Transplant 2017 Feb;15(Suppl 1):128-132. doi: 10.6002/ect.mesot2016.P11. PMID: 28260452

Therapy

Mortality from liver angiosarcoma, hepatocellular carcinoma, and cirrhosis among vinyl chloride workers.
Fedeli U, Girardi P, Gardiman G, Zara D, Scoizzato L, Ballarin MN, Baccini M, Pirastu R, Comba P, Mastrangelo G
Am J Ind Med 2019 Jan;62(1):14-20. Epub 2018 Nov 25 doi: 10.1002/ajim.22922. PMID: 30474170
A pooled analysis of treatment and prognosis of hepatic angiosarcoma in adults.
Li DB, Si XY, Wan T, Zhou YM
Hepatobiliary Pancreat Dis Int 2018 Jun;17(3):198-203. Epub 2018 Apr 23 doi: 10.1016/j.hbpd.2018.04.005. PMID: 29724676
Unusual Indications for a Liver Transplant: A Single-Center Experience.
Akdur A, Kirnap M, Ayvazoglu Soy EH, Ozcay F, Moray G, Arslan G, Haberal M
Exp Clin Transplant 2017 Feb;15(Suppl 1):128-132. doi: 10.6002/ect.mesot2016.P11. PMID: 28260452
Toxicity of vinyl chloride and poly(vinyl chloride): a critical review.
Wagoner JK
Environ Health Perspect 1983 Oct;52:61-6. doi: 10.1289/ehp.835261. PMID: 6360677Free PMC Article
Arsenic--state of the art.
Landrigan PJ
Am J Ind Med 1981;2(1):5-14. doi: 10.1002/ajim.4700020104. PMID: 6295141

Prognosis

Management Strategies and Outcomes in Primary Liver Angiosarcoma.
Ramakrishnan N, Mokhtari R, Charville GW, Bui N, Ganjoo K
Am J Clin Oncol 2023 Oct 1;46(10):439-444. Epub 2023 Aug 15 doi: 10.1097/COC.0000000000001032. PMID: 37580871Free PMC Article
EASL clinical practice guidelines for the management of occupational liver diseases.
Colombo M
Liver Int 2020 Feb;40 Suppl 1:136-141. doi: 10.1111/liv.14349. PMID: 32077606
Mortality from liver angiosarcoma, hepatocellular carcinoma, and cirrhosis among vinyl chloride workers.
Fedeli U, Girardi P, Gardiman G, Zara D, Scoizzato L, Ballarin MN, Baccini M, Pirastu R, Comba P, Mastrangelo G
Am J Ind Med 2019 Jan;62(1):14-20. Epub 2018 Nov 25 doi: 10.1002/ajim.22922. PMID: 30474170
A pooled analysis of treatment and prognosis of hepatic angiosarcoma in adults.
Li DB, Si XY, Wan T, Zhou YM
Hepatobiliary Pancreat Dis Int 2018 Jun;17(3):198-203. Epub 2018 Apr 23 doi: 10.1016/j.hbpd.2018.04.005. PMID: 29724676
Angiosarcoma of the liver as a cause of fulminant liver failure.
Montell García M, Romero Cabello R, Romero Feregrino R, Atri Moises M, Trejo Estrada R, Alvaro PR, Moreno Manlio Gerardo G, Feregrino Rodrigo R
BMJ Case Rep 2012 Aug 2;2012 doi: 10.1136/bcr-2012-006417. PMID: 22865805Free PMC Article

Clinical prediction guides

EASL clinical practice guidelines for the management of occupational liver diseases.
Colombo M
Liver Int 2020 Feb;40 Suppl 1:136-141. doi: 10.1111/liv.14349. PMID: 32077606
Occupational exposure to vinyl chloride and cancer risk: a review of the epidemiologic literature.
Bosetti C, La Vecchia C, Lipworth L, McLaughlin JK
Eur J Cancer Prev 2003 Oct;12(5):427-30. doi: 10.1097/00008469-200310000-00012. PMID: 14512808
Update of the follow-up of mortality and cancer incidence among European workers employed in the vinyl chloride industry.
Ward E, Boffetta P, Andersen A, Colin D, Comba P, Deddens JA, De Santis M, Engholm G, Hagmar L, Langard S, Lundberg I, McElvenny D, Pirastu R, Sali D, Simonato L
Epidemiology 2001 Nov;12(6):710-8. doi: 10.1097/00001648-200111000-00021. PMID: 11679801
Predicting cancer risk from vinyl chloride exposure with a physiologically based pharmacokinetic model.
Reitz RH, Gargas ML, Andersen ME, Provan WM, Green TL
Toxicol Appl Pharmacol 1996 Apr;137(2):253-67. doi: 10.1006/taap.1996.0079. PMID: 8661351
Toxicity of vinyl chloride and polyvinyl chloride as seen through epidemiologic observations.
Wagoner JK, Infante PF, Apfeldorf RB
J Toxicol Environ Health 1980 Sep-Nov;6(5-6):1101-7. doi: 10.1080/15287398009529930. PMID: 7193250

Recent systematic reviews

The lymphocyte cytokinesis block micronucleus test in human populations occupationally exposed to vinyl chloride: A systematic review and meta-analysis.
Bolognesi C, Bruzzone M, Ceppi M, Kirsch-Volders M
Mutat Res Rev Mutat Res 2017 Oct;774:1-11. Epub 2017 Jul 31 doi: 10.1016/j.mrrev.2017.07.003. PMID: 29173494

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