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Disease of liver

MedGen UID:
9792
Concept ID:
C0023895
Disease or Syndrome
Synonyms: Disease, Liver; Diseases, Liver; Liver Disease; Liver Diseases
SNOMED CT: Hepatopathy (235856003); Liver disease (235856003); Disorder of liver (235856003); LD - Liver disease (235856003); Disease of liver (235856003)

Definition

A non-neoplastic or neoplastic disorder that affects the liver parenchyma and intrahepatic bile ducts. Representative examples of non-neoplastic disorders include hepatitis, cirrhosis, cholangitis, and polycystic liver disease. Representative examples of neoplastic disorders include hepatocellular adenoma, hepatocellular carcinoma, intrahepatic cholangiocarcinoma, lymphoma, and angiosarcoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDisease of liver

Professional guidelines

PubMed

Jophlin LL, Singal AK, Bataller R, Wong RJ, Sauer BG, Terrault NA, Shah VH
Am J Gastroenterol 2024 Jan 1;119(1):30-54. Epub 2023 Sep 1 doi: 10.14309/ajg.0000000000002572. PMID: 38174913Free PMC Article
Brown ZJ, Tsilimigras DI, Ruff SM, Mohseni A, Kamel IR, Cloyd JM, Pawlik TM
JAMA Surg 2023 Apr 1;158(4):410-420. doi: 10.1001/jamasurg.2022.7989. PMID: 36790767
European Association for the Study of the Liver; Clinical Practice Guideline Panel: Chair:; Panel members; EASL Governing Board representative:
J Hepatol 2019 Jun;70(6):1222-1261. Epub 2019 Mar 27 doi: 10.1016/j.jhep.2019.02.014. PMID: 30926241

Recent clinical studies

Etiology

Garrido I, Marques M, Liberal R, Cardoso H, Lopes S, Macedo G
Orphanet J Rare Dis 2022 Feb 23;17(1):82. doi: 10.1186/s13023-022-02245-5. PMID: 35197085Free PMC Article
Chen CT, Liu CY, Yu YB, Liu CJ, Hsiao LT, Gau JP, Chiou TJ, Liu JH, Liu YC
PLoS One 2017;12(9):e0185210. Epub 2017 Sep 21 doi: 10.1371/journal.pone.0185210. PMID: 28934311Free PMC Article
Al-Lawati TT
Arab J Gastroenterol 2013 Dec;14(4):173-5. Epub 2013 Dec 23 doi: 10.1016/j.ajg.2013.11.004. PMID: 24433648
Sonika U, Kar P
Trop Gastroenterol 2012 Apr-Jun;33(2):102-6. doi: 10.7869/tg.2012.25. PMID: 23025055
Hurley TR, Whisler WW, Clasen RA, Smith MC, Bleck TP, Doolas A, Dampier MF
Neurosurgery 1994 Jul;35(1):148-51. doi: 10.1227/00006123-199407000-00024. PMID: 7936138

Diagnosis

Al-Lawati TT
Arab J Gastroenterol 2013 Dec;14(4):173-5. Epub 2013 Dec 23 doi: 10.1016/j.ajg.2013.11.004. PMID: 24433648
Shah PK, Chittora MD, Deo IN, Khangarot D, Vyas MM, Tak RS
J Assoc Physicians India 1987 Mar;35(3):240-2. PMID: 3611010
Mazumdar TN, Chandra U, Tandon HD
J Assoc Physicians India 1979 Jul;27(7):631-5. PMID: 541326
Lum G, Gambino SR
Clin Chem 1972 Apr;18(4):358-62. PMID: 5012259
Blackburn CR, Woolcock AJ
J R Coll Physicians Lond 1971 Apr;5(3):241-9. PMID: 4361121Free PMC Article

Therapy

Garrido I, Marques M, Liberal R, Cardoso H, Lopes S, Macedo G
Orphanet J Rare Dis 2022 Feb 23;17(1):82. doi: 10.1186/s13023-022-02245-5. PMID: 35197085Free PMC Article
Chen CT, Liu CY, Yu YB, Liu CJ, Hsiao LT, Gau JP, Chiou TJ, Liu JH, Liu YC
PLoS One 2017;12(9):e0185210. Epub 2017 Sep 21 doi: 10.1371/journal.pone.0185210. PMID: 28934311Free PMC Article
Sonika U, Kar P
Trop Gastroenterol 2012 Apr-Jun;33(2):102-6. doi: 10.7869/tg.2012.25. PMID: 23025055
Datta DV, Khuroo MS, Mattocks AR, Aikat BK, Chhuttani PN
J Assoc Physicians India 1978 May;26(5):383-93, vii-viii. PMID: 730719
Tandon BN, Tandon HD, Tandon RK, Narndranathan M, Joshi YK
Lancet 1976 Aug 7;2(7980):271-2. doi: 10.1016/s0140-6736(76)90727-3. PMID: 59849

Prognosis

Garrido I, Marques M, Liberal R, Cardoso H, Lopes S, Macedo G
Orphanet J Rare Dis 2022 Feb 23;17(1):82. doi: 10.1186/s13023-022-02245-5. PMID: 35197085Free PMC Article
Chen CT, Liu CY, Yu YB, Liu CJ, Hsiao LT, Gau JP, Chiou TJ, Liu JH, Liu YC
PLoS One 2017;12(9):e0185210. Epub 2017 Sep 21 doi: 10.1371/journal.pone.0185210. PMID: 28934311Free PMC Article
Al-Lawati TT
Arab J Gastroenterol 2013 Dec;14(4):173-5. Epub 2013 Dec 23 doi: 10.1016/j.ajg.2013.11.004. PMID: 24433648
Hurley TR, Whisler WW, Clasen RA, Smith MC, Bleck TP, Doolas A, Dampier MF
Neurosurgery 1994 Jul;35(1):148-51. doi: 10.1227/00006123-199407000-00024. PMID: 7936138
Saebø A, Lassen J
Scand J Infect Dis 1991;23(5):517-27. doi: 10.3109/00365549109105172. PMID: 1767249

Clinical prediction guides

Liu M, Jia Z, Yao T, Zhang G, Wang X
Parkinsonism Relat Disord 2024 Jun;123:106560. Epub 2024 Mar 18 doi: 10.1016/j.parkreldis.2024.106560. PMID: 38518544
Chen CT, Liu CY, Yu YB, Liu CJ, Hsiao LT, Gau JP, Chiou TJ, Liu JH, Liu YC
PLoS One 2017;12(9):e0185210. Epub 2017 Sep 21 doi: 10.1371/journal.pone.0185210. PMID: 28934311Free PMC Article
Wu ZF, Zhou XH, Hu YW, Zhou LY, Gao YB, Peng XH, Yang XH, Zhang JY, Hu Y, Zeng ZC
Cancer Immunol Immunother 2014 Mar;63(3):235-45. Epub 2013 Dec 15 doi: 10.1007/s00262-013-1504-9. PMID: 24337704Free PMC Article
Al-Lawati TT
Arab J Gastroenterol 2013 Dec;14(4):173-5. Epub 2013 Dec 23 doi: 10.1016/j.ajg.2013.11.004. PMID: 24433648
Saebø A, Lassen J
Scand J Infect Dis 1991;23(5):517-27. doi: 10.3109/00365549109105172. PMID: 1767249

Recent systematic reviews

Supplemental Content

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