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Metastatic Malignant Neoplasm in the Large Intestine

MedGen UID:
138071
Concept ID:
C0346973
Neoplastic Process
Synonyms: Cancer metastatic to large intestine; Metastases to Large Intestine; Metastasis to Large Bowel; Metastasis to large intestine; Metastasis to the Large Bowel; Metastasis to the Large Intestine; Metastatic malignant neoplasm of large intestine; Metastatic malignant neoplasm to large intestine; Metastatic Malignant Neoplasm to the Large Intestine; Metastatic Neoplasm to the Large Intestine; Metastatic Tumor to the Large Intestine; Secondary malignant neoplasm of large intestine
SNOMED CT: Metastasis to large intestine (94365007); Secondary malignant neoplasm of large intestine (94365007); Metastatic malignant neoplasm to large intestine (94365007); Cancer metastatic to large intestine (94365007); Metastatic malignant neoplasm of large intestine (94365007)

Definition

The spread of a malignant neoplasm to the large intestine. This may be from a primary large intestine malignant neoplasm, or from a malignant neoplasm at a distant site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Large Intestine

Professional guidelines

PubMed

Lonardi S, Pietrantonio F
Nat Rev Gastroenterol Hepatol 2024 Feb;21(2):76-77. doi: 10.1038/s41575-023-00881-1. PMID: 38066100
Vera R, Salgado M, Safont MJ, Gallego J, González E, Élez E, Aranda E
Clin Transl Oncol 2021 Apr;23(4):827-839. Epub 2020 Aug 13 doi: 10.1007/s12094-020-02475-8. PMID: 32789773Free PMC Article
Kasprzak A, Adamek A
Int J Mol Sci 2020 May 15;21(10) doi: 10.3390/ijms21103494. PMID: 32429087Free PMC Article

Recent clinical studies

Etiology

Liu S, Jiang T, Xiao L, Yang S, Liu Q, Gao Y, Chen G, Xiao W
Oncologist 2021 Sep;26(9):e1555-e1566. Epub 2021 Jun 7 doi: 10.1002/onco.13824. PMID: 33987952Free PMC Article
Cohen EEW, Soulières D, Le Tourneau C, Dinis J, Licitra L, Ahn MJ, Soria A, Machiels JP, Mach N, Mehra R, Burtness B, Zhang P, Cheng J, Swaby RF, Harrington KJ; KEYNOTE-040 investigators
Lancet 2019 Jan 12;393(10167):156-167. Epub 2018 Nov 30 doi: 10.1016/S0140-6736(18)31999-8. PMID: 30509740
Lin J, Goldblum JR, Bennett AE, Bronner MP, Liu X
Am J Surg Pathol 2012 Feb;36(2):292-5. doi: 10.1097/PAS.0b013e318236e4d2. PMID: 22082602
Schmiegel W, Pox C, Reinacher-Schick A, Adler G, Arnold D, Fleig W, Fölsch UR, Frühmorgen P, Graeven U, Heinemann V, Hohenberger W, Holstege A, Junginger T, Kopp I, Kühlbacher T, Porschen R, Propping P, Riemann JF, Rödel C, Sauer R, Sauerbruch T, Schmitt W, Schmoll HJ, Seufferlein T, Zeitz M, Selbmann HK; Federal Committee of Physicians and Health Insurers
Z Gastroenterol 2010 Jan;48(1):65-136. Epub 2010 Jan 13 doi: 10.1055/s-0028-1109936. PMID: 20072998
Pöschl G, Seitz HK
Alcohol Alcohol 2004 May-Jun;39(3):155-65. doi: 10.1093/alcalc/agh057. PMID: 15082451

Diagnosis

Argumánez Tello V, Sánchez-Montes C, Mínguez Sabater A, Bauza M, Bustamante-Balén M
Rev Esp Enferm Dig 2023 Dec;115(12):732-733. doi: 10.17235/reed.2023.9543/2023. PMID: 36926922
Shichijo S, Hara H, Uedo N, Michida T, Takeuchi Y
Endoscopy 2022 Dec;54(S 02):E956-E957. Epub 2022 Jul 21 doi: 10.1055/a-1882-4942. PMID: 35863340Free PMC Article
Ishtiaq R, Aziz M, Wilhelm DM, Gaduputi VV, Hamdani SU
J Gastrointest Cancer 2021 Mar;52(1):359-364. doi: 10.1007/s12029-020-00470-4. PMID: 32761320
Robertson RG, Geiger WJ, Davis NB
Am Fam Physician 2006 Aug 1;74(3):429-34. PMID: 16913162
Feuerbach S
Endoscopy 1993 Jan;25(1):108-16. doi: 10.1055/s-2007-1010268. PMID: 8453920

Therapy

Guo C, Chen MZ, Chiu T, Condous G, Barto W
Aust N Z J Obstet Gynaecol 2023 Dec;63(6):792-796. Epub 2023 Jul 10 doi: 10.1111/ajo.13730. PMID: 37427888
Liu S, Jiang T, Xiao L, Yang S, Liu Q, Gao Y, Chen G, Xiao W
Oncologist 2021 Sep;26(9):e1555-e1566. Epub 2021 Jun 7 doi: 10.1002/onco.13824. PMID: 33987952Free PMC Article
Ishtiaq R, Aziz M, Wilhelm DM, Gaduputi VV, Hamdani SU
J Gastrointest Cancer 2021 Mar;52(1):359-364. doi: 10.1007/s12029-020-00470-4. PMID: 32761320
Cohen EEW, Soulières D, Le Tourneau C, Dinis J, Licitra L, Ahn MJ, Soria A, Machiels JP, Mach N, Mehra R, Burtness B, Zhang P, Cheng J, Swaby RF, Harrington KJ; KEYNOTE-040 investigators
Lancet 2019 Jan 12;393(10167):156-167. Epub 2018 Nov 30 doi: 10.1016/S0140-6736(18)31999-8. PMID: 30509740
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article

Prognosis

Janjic O, Labgaa I, Hübner M, Demartines N, Joliat GR
Eur J Surg Oncol 2022 Apr;48(4):822-833. Epub 2021 Oct 10 doi: 10.1016/j.ejso.2021.10.004. PMID: 34656391
Horn SR, Stoltzfus KC, Lehrer EJ, Dawson LA, Tchelebi L, Gusani NJ, Sharma NK, Chen H, Trifiletti DM, Zaorsky NG
Cancer Epidemiol 2020 Aug;67:101760. Epub 2020 Jun 17 doi: 10.1016/j.canep.2020.101760. PMID: 32562887
Chrysanthos NV, Nezi V, Zafiropoulou R, Papatheodoridis G, Manesis E
Am J Gastroenterol 2018 Oct;113(10):1427. doi: 10.1038/s41395-018-0099-3. PMID: 29891852
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article
Schmiegel W, Pox C, Reinacher-Schick A, Adler G, Arnold D, Fleig W, Fölsch UR, Frühmorgen P, Graeven U, Heinemann V, Hohenberger W, Holstege A, Junginger T, Kopp I, Kühlbacher T, Porschen R, Propping P, Riemann JF, Rödel C, Sauer R, Sauerbruch T, Schmitt W, Schmoll HJ, Seufferlein T, Zeitz M, Selbmann HK; Federal Committee of Physicians and Health Insurers
Z Gastroenterol 2010 Jan;48(1):65-136. Epub 2010 Jan 13 doi: 10.1055/s-0028-1109936. PMID: 20072998

Clinical prediction guides

Colles T, Ziegelmann PK, Damin DC
Int J Colorectal Dis 2023 Sep 15;38(1):230. doi: 10.1007/s00384-023-04524-4. PMID: 37712988
Kelly ME, Heriot AG
Dis Colon Rectum 2023 Mar 1;66(3):355-357. Epub 2023 Jan 4 doi: 10.1097/DCR.0000000000002706. PMID: 36728599
Rahma OE, Yothers G, Hong TS, Russell MM, You YN, Parker W, Jacobs SA, Colangelo LH, Lucas PC, Gollub MJ, Hall WA, Kachnic LA, Vijayvergia N, O'Rourke MA, Faller BA, Valicenti RK, Schefter TE, George S, Kainthla R, Stella PJ, Sigurdson E, Wolmark N, George TJ
JAMA Oncol 2021 Aug 1;7(8):1225-1230. doi: 10.1001/jamaoncol.2021.1683. PMID: 34196693Free PMC Article
Copija A, Waniczek D, Witkoś A, Walkiewicz K, Nowakowska-Zajdel E
Int J Mol Sci 2017 Jan 6;18(1) doi: 10.3390/ijms18010107. PMID: 28067827Free PMC Article
Palefsky JM
Sex Health 2012 Dec;9(6):580-6. doi: 10.1071/SH12045. PMID: 23380236

Recent systematic reviews

Colles T, Ziegelmann PK, Damin DC
Int J Colorectal Dis 2023 Sep 15;38(1):230. doi: 10.1007/s00384-023-04524-4. PMID: 37712988
Janjic O, Labgaa I, Hübner M, Demartines N, Joliat GR
Eur J Surg Oncol 2022 Apr;48(4):822-833. Epub 2021 Oct 10 doi: 10.1016/j.ejso.2021.10.004. PMID: 34656391
Liu S, Jiang T, Xiao L, Yang S, Liu Q, Gao Y, Chen G, Xiao W
Oncologist 2021 Sep;26(9):e1555-e1566. Epub 2021 Jun 7 doi: 10.1002/onco.13824. PMID: 33987952Free PMC Article
Mahendran B, Rossi B, Coleman M, Smolarek S
Tech Coloproctol 2020 Jul;24(7):685-694. Epub 2020 May 6 doi: 10.1007/s10151-020-02200-1. PMID: 32377984
Stein A, Folprecht G
Oncol Res Treat 2018;41(5):282-285. Epub 2018 Apr 26 doi: 10.1159/000488918. PMID: 29705788

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