U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Intestinal cancer

MedGen UID:
87562
Concept ID:
C0346627
Neoplastic Process
Synonyms: Cancer of Intestines; Cancer of the Intestines; Cancer, Intestinal; Cancer, Intestines; Cancers, Intestinal; Cancers, Intestines; Intestinal Cancer; Intestinal Cancers; Intestines Cancer; Intestines Cancers
SNOMED CT: Cancer of intestine (363508008); Malignant neoplasm of intestine (363508008); CA - Cancer of intestine (363508008); Intestinal cancer (363508008); Cancer of bowel (363508008); CA - Cancer of bowel (363508008); Malignant tumor of intestine (363508008)
 
Monarch Initiative: MONDO:0005814

Definition

A primary or metastatic malignant neoplasm involving the small intestine, large intestine, or both. Representative examples are carcinomas, lymphomas, and sarcomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntestinal cancer

Professional guidelines

PubMed

Fei Y, Ma Y, Zhang H, Li H, Feng G, Fang J
J Nanobiotechnology 2022 Sep 29;20(1):430. doi: 10.1186/s12951-022-01517-3. PMID: 36175955Free PMC Article
Menahem B, Alves A, Regimbeau JM, Sabbagh C
J Visc Surg 2019 Dec;156(6):507-514. Epub 2019 Aug 21 doi: 10.1016/j.jviscsurg.2019.07.009. PMID: 31445799
Boivin GP, Washington K, Yang K, Ward JM, Pretlow TP, Russell R, Besselsen DG, Godfrey VL, Doetschman T, Dove WF, Pitot HC, Halberg RB, Itzkowitz SH, Groden J, Coffey RJ
Gastroenterology 2003 Mar;124(3):762-77. doi: 10.1053/gast.2003.50094. PMID: 12612914

Recent clinical studies

Etiology

Friedberg S, Rubin DT
Gastroenterol Clin North Am 2022 Jun;51(2):369-379. Epub 2022 Apr 22 doi: 10.1016/j.gtc.2021.12.011. PMID: 35595420
Al-Ishaq RK, Overy AJ, Büsselberg D
Biomolecules 2020 Jan 8;10(1) doi: 10.3390/biom10010105. PMID: 31936288Free PMC Article
Fu T, Coulter S, Yoshihara E, Oh TG, Fang S, Cayabyab F, Zhu Q, Zhang T, Leblanc M, Liu S, He M, Waizenegger W, Gasser E, Schnabl B, Atkins AR, Yu RT, Knight R, Liddle C, Downes M, Evans RM
Cell 2019 Feb 21;176(5):1098-1112.e18. doi: 10.1016/j.cell.2019.01.036. PMID: 30794774Free PMC Article
Schulz-Heddergott R, Stark N, Edmunds SJ, Li J, Conradi LC, Bohnenberger H, Ceteci F, Greten FR, Dobbelstein M, Moll UM
Cancer Cell 2018 Aug 13;34(2):298-314.e7. doi: 10.1016/j.ccell.2018.07.004. PMID: 30107178Free PMC Article
Aaltonen LA
Semin Cancer Biol 2000 Aug;10(4):289-98. doi: 10.1006/scbi.2000.0148. PMID: 10966851

Diagnosis

Pitra M, Karnos V
Rozhl Chir 2023 Spring;102(2):85-87. doi: 10.33699/PIS.2023.102.2.85-87. PMID: 37185031
Cavestro GM, Mannucci A, Balaguer F, Hampel H, Kupfer SS, Repici A, Sartore-Bianchi A, Seppälä TT, Valentini V, Boland CR, Brand RE, Buffart TE, Burke CA, Caccialanza R, Cannizzaro R, Cascinu S, Cercek A, Crosbie EJ, Danese S, Dekker E, Daca-Alvarez M, Deni F, Dominguez-Valentin M, Eng C, Goel A, Guillem JG, Houwen BBSL, Kahi C, Kalady MF, Kastrinos F, Kühn F, Laghi L, Latchford A, Liska D, Lynch P, Malesci A, Mauri G, Meldolesi E, Møller P, Monahan KJ, Möslein G, Murphy CC, Nass K, Ng K, Oliani C, Papaleo E, Patel SG, Puzzono M, Remo A, Ricciardiello L, Ripamonti CI, Siena S, Singh SK, Stadler ZK, Stanich PP, Syngal S, Turi S, Urso ED, Valle L, Vanni VS, Vilar E, Vitellaro M, You YN, Yurgelun MB, Zuppardo RA, Stoffel EM; Associazione Italiana Familiarità Ereditarietà Tumori; Collaborative Group of the Americas on Inherited Gastrointestinal Cancer; European Hereditary Tumour Group, and the International Society for Gastrointestinal Hereditary Tumours
Clin Gastroenterol Hepatol 2023 Mar;21(3):581-603.e33. Epub 2022 Dec 20 doi: 10.1016/j.cgh.2022.12.006. PMID: 36549470Free PMC Article
Friedberg S, Rubin DT
Gastroenterol Clin North Am 2022 Jun;51(2):369-379. Epub 2022 Apr 22 doi: 10.1016/j.gtc.2021.12.011. PMID: 35595420
Mimori K, Shinden Y, Eguchi H, Sudo T, Sugimachi K
Int J Clin Oncol 2013 Oct;18(5):762-5. Epub 2013 Jul 5 doi: 10.1007/s10147-013-0587-9. PMID: 23828632
Aaltonen LA
Semin Cancer Biol 2000 Aug;10(4):289-98. doi: 10.1006/scbi.2000.0148. PMID: 10966851

Therapy

Fei Y, Ma Y, Zhang H, Li H, Feng G, Fang J
J Nanobiotechnology 2022 Sep 29;20(1):430. doi: 10.1186/s12951-022-01517-3. PMID: 36175955Free PMC Article
Akagi K, Oki E, Taniguchi H, Nakatani K, Aoki D, Kuwata T, Yoshino T
Cancer Sci 2021 Mar;112(3):1105-1113. Epub 2021 Feb 7 doi: 10.1111/cas.14798. PMID: 33403729Free PMC Article
Al-Ishaq RK, Overy AJ, Büsselberg D
Biomolecules 2020 Jan 8;10(1) doi: 10.3390/biom10010105. PMID: 31936288Free PMC Article
Hor T
J Visc Surg 2018 Jun;155 Suppl 1:S49-S55. Epub 2018 May 30 doi: 10.1016/j.jviscsurg.2018.04.006. PMID: 29857942
Waterhouse JA
Ann Occup Hyg 1972 Apr;15(1):43-5. doi: 10.1093/annhyg/15.1.43. PMID: 5065167

Prognosis

Llach J, Pellisé M, Monahan K
Best Pract Res Clin Gastroenterol 2022 Jun-Aug;58-59:101790. Epub 2022 Mar 26 doi: 10.1016/j.bpg.2022.101790. PMID: 35988964
Akagi K, Oki E, Taniguchi H, Nakatani K, Aoki D, Kuwata T, Yoshino T
Cancer Sci 2021 Mar;112(3):1105-1113. Epub 2021 Feb 7 doi: 10.1111/cas.14798. PMID: 33403729Free PMC Article
Al-Ishaq RK, Overy AJ, Büsselberg D
Biomolecules 2020 Jan 8;10(1) doi: 10.3390/biom10010105. PMID: 31936288Free PMC Article
Maddocks ODK, Athineos D, Cheung EC, Lee P, Zhang T, van den Broek NJF, Mackay GM, Labuschagne CF, Gay D, Kruiswijk F, Blagih J, Vincent DF, Campbell KJ, Ceteci F, Sansom OJ, Blyth K, Vousden KH
Nature 2017 Apr 19;544(7650):372-376. doi: 10.1038/nature22056. PMID: 28425994
Gammon A, Jasperson K, Kohlmann W, Burt RW
Best Pract Res Clin Gastroenterol 2009;23(2):219-31. doi: 10.1016/j.bpg.2009.02.007. PMID: 19414148Free PMC Article

Clinical prediction guides

Pfefferkorn RM, Mortzfeld BM, Fink C, Frieling JV, Bossen J, Esser D, Kaleta C, Rosenstiel P, Heine H, Roeder T
Aging Dis 2024 Feb 1;15(1):226-244. doi: 10.14336/AD.2023.0517. PMID: 37962464Free PMC Article
Valle L, Monahan KJ
Lancet Gastroenterol Hepatol 2024 Jan;9(1):68-82. Epub 2023 Nov 4 doi: 10.1016/S2468-1253(23)00240-6. PMID: 37931640
Akagi K, Oki E, Taniguchi H, Nakatani K, Aoki D, Kuwata T, Yoshino T
Cancer Sci 2021 Mar;112(3):1105-1113. Epub 2021 Feb 7 doi: 10.1111/cas.14798. PMID: 33403729Free PMC Article
Maddocks ODK, Athineos D, Cheung EC, Lee P, Zhang T, van den Broek NJF, Mackay GM, Labuschagne CF, Gay D, Kruiswijk F, Blagih J, Vincent DF, Campbell KJ, Ceteci F, Sansom OJ, Blyth K, Vousden KH
Nature 2017 Apr 19;544(7650):372-376. doi: 10.1038/nature22056. PMID: 28425994
Zeuzem S
Int J Colorectal Dis 2000 Apr;15(2):59-82. doi: 10.1007/s003840050236. PMID: 10855547

Recent systematic reviews

Hintzen KFH, Grote J, Wintjens AGWE, Lubbers T, Eussen MMM, van Schooten FJ, Bouvy ND, Peeters A
BJS Open 2021 Mar 5;5(2) doi: 10.1093/bjsopen/zrab013. PMID: 33855362Free PMC Article
Uchino M, Ikeuchi H, Hata K, Minagawa T, Horio Y, Kuwahara R, Nakamura S, Watanabe K, Saruta M, Fujii T, Kobayashi T, Sugimoto K, Hirai F, Esaki M, Hiraoka S, Matsuoka K, Shinzaki S, Matsuura M, Inoue N, Nakase H, Watanabe M
J Gastroenterol Hepatol 2021 Feb;36(2):329-336. Epub 2020 Sep 30 doi: 10.1111/jgh.15229. PMID: 32865278
Lo B, Zhao M, Vind I, Burisch J
Clin Gastroenterol Hepatol 2021 Jun;19(6):1117-1138.e19. Epub 2020 Aug 13 doi: 10.1016/j.cgh.2020.08.015. PMID: 32801010
Musio D, De Felice F, Raffetto N, Tombolini V
Radiat Oncol 2014 Jan 28;9:39. doi: 10.1186/1748-717X-9-39. PMID: 24472223Free PMC Article
Pedersen N, Duricova D, Elkjaer M, Gamborg M, Munkholm P, Jess T
Am J Gastroenterol 2010 Jul;105(7):1480-7. Epub 2010 Mar 23 doi: 10.1038/ajg.2009.760. PMID: 20332773

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...