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Testicular lymphoma

MedGen UID:
138110
Concept ID:
C0349644
Neoplastic Process
Synonyms: Lymphoma of Testis; lymphoma of testis; Lymphoma of the Testis; lymphoma of the testis; Malignant lymphoma of testis; malignant lymphoma of testis; Primary Testicular Lymphoma; primary testicular lymphoma; Testicular Lymphoma; testicular lymphoma; TLYM
SNOMED CT: Malignant lymphoma of testis (277664004)
 
Monarch Initiative: MONDO:0001472

Definition

A lymphoma that arises from the testis and is not associated with lymphoma in another anatomic site. [from NCI]

Professional guidelines

PubMed

Ollila TA, Olszewski AJ
Leuk Lymphoma 2019 Feb;60(2):523-526. Epub 2018 Jul 3 doi: 10.1080/10428194.2018.1480776. PMID: 29966467Free PMC Article
Cheah CY, Wirth A, Seymour JF
Blood 2014 Jan 23;123(4):486-93. Epub 2013 Nov 26 doi: 10.1182/blood-2013-10-530659. PMID: 24282217
Brouwer CL, Wiesendanger EM, van der Hulst PC, van Imhoff GW, Langendijk JA, Beijert M
Int J Radiat Oncol Biol Phys 2013 Feb 1;85(2):298-308. Epub 2012 Jul 24 doi: 10.1016/j.ijrobp.2012.06.019. PMID: 22836054

Recent clinical studies

Etiology

Poeschel V, Held G, Ziepert M, Witzens-Harig M, Holte H, Thurner L, Borchmann P, Viardot A, Soekler M, Keller U, Schmidt C, Truemper L, Mahlberg R, Marks R, Hoeffkes HG, Metzner B, Dierlamm J, Frickhofen N, Haenel M, Neubauer A, Kneba M, Merli F, Tucci A, de Nully Brown P, Federico M, Lengfelder E, di Rocco A, Trappe R, Rosenwald A, Berdel C, Maisenhoelder M, Shpilberg O, Amam J, Christofyllakis K, Hartmann F, Murawski N, Stilgenbauer S, Nickelsen M, Wulf G, Glass B, Schmitz N, Altmann B, Loeffler M, Pfreundschuh M; FLYER Trial Investigators; German Lymphoma Alliance
Lancet 2019 Dec 21;394(10216):2271-2281. doi: 10.1016/S0140-6736(19)33008-9. PMID: 31868632
Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605Free PMC Article
Vitolo U, Chiappella A, Ferreri AJ, Martelli M, Baldi I, Balzarotti M, Bottelli C, Conconi A, Gomez H, Lopez-Guillermo A, Martinelli G, Merli F, Novero D, Orsucci L, Pavone V, Ricardi U, Storti S, Gospodarowicz MK, Cavalli F, Sarris AH, Zucca E
J Clin Oncol 2011 Jul 10;29(20):2766-72. Epub 2011 Jun 6 doi: 10.1200/JCO.2010.31.4187. PMID: 21646602
Miedler JD, MacLennan GT
J Urol 2007 Dec;178(6):2645. Epub 2007 Oct 22 doi: 10.1016/j.juro.2007.09.012. PMID: 17945289
Warikoo S, Gonick P
Urology 1975 Feb;5(2):261-4. doi: 10.1016/0090-4295(75)90028-x. PMID: 1090055

Diagnosis

Shimada K, Yamaguchi M, Atsuta Y, Matsue K, Sato K, Kusumoto S, Nagai H, Takizawa J, Fukuhara N, Nagafuji K, Miyazaki K, Ohtsuka E, Okamoto M, Sugita Y, Uchida T, Kayukawa S, Wake A, Ennishi D, Kondo Y, Izumi T, Kin Y, Tsukasaki K, Hashimoto D, Yuge M, Yanagisawa A, Kuwatsuka Y, Shimada S, Masaki Y, Niitsu N, Kiyoi H, Suzuki R, Tokunaga T, Nakamura S, Kinoshita T
Lancet Oncol 2020 Apr;21(4):593-602. Epub 2020 Mar 11 doi: 10.1016/S1470-2045(20)30059-0. PMID: 32171071
Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605Free PMC Article
Johnson S, Feldman M, Krishnamurthi V
J Urol 2015 Jan;193(1):315-6. Epub 2014 Oct 16 doi: 10.1016/j.juro.2014.10.051. PMID: 25444963
Cheah CY, Wirth A, Seymour JF
Blood 2014 Jan 23;123(4):486-93. Epub 2013 Nov 26 doi: 10.1182/blood-2013-10-530659. PMID: 24282217
Ahmad SS, Idris SF, Follows GA, Williams MV
Clin Oncol (R Coll Radiol) 2012 Jun;24(5):358-65. Epub 2012 Mar 17 doi: 10.1016/j.clon.2012.02.005. PMID: 22424983

Therapy

Poeschel V, Held G, Ziepert M, Witzens-Harig M, Holte H, Thurner L, Borchmann P, Viardot A, Soekler M, Keller U, Schmidt C, Truemper L, Mahlberg R, Marks R, Hoeffkes HG, Metzner B, Dierlamm J, Frickhofen N, Haenel M, Neubauer A, Kneba M, Merli F, Tucci A, de Nully Brown P, Federico M, Lengfelder E, di Rocco A, Trappe R, Rosenwald A, Berdel C, Maisenhoelder M, Shpilberg O, Amam J, Christofyllakis K, Hartmann F, Murawski N, Stilgenbauer S, Nickelsen M, Wulf G, Glass B, Schmitz N, Altmann B, Loeffler M, Pfreundschuh M; FLYER Trial Investigators; German Lymphoma Alliance
Lancet 2019 Dec 21;394(10216):2271-2281. doi: 10.1016/S0140-6736(19)33008-9. PMID: 31868632
Cheah CY, Wirth A, Seymour JF
Blood 2014 Jan 23;123(4):486-93. Epub 2013 Nov 26 doi: 10.1182/blood-2013-10-530659. PMID: 24282217
Vitolo U, Chiappella A, Ferreri AJ, Martelli M, Baldi I, Balzarotti M, Bottelli C, Conconi A, Gomez H, Lopez-Guillermo A, Martinelli G, Merli F, Novero D, Orsucci L, Pavone V, Ricardi U, Storti S, Gospodarowicz MK, Cavalli F, Sarris AH, Zucca E
J Clin Oncol 2011 Jul 10;29(20):2766-72. Epub 2011 Jun 6 doi: 10.1200/JCO.2010.31.4187. PMID: 21646602
Thomas LC, Adonizio C, Filicko-O'Hara J, Golshayan AR, Costa LJ, Morris GJ
Semin Oncol 2010 Dec;37(6):549-54. doi: 10.1053/j.seminoncol.2010.10.022. PMID: 21167372
Warikoo S, Gonick P
Urology 1975 Feb;5(2):261-4. doi: 10.1016/0090-4295(75)90028-x. PMID: 1090055

Prognosis

Poeschel V, Held G, Ziepert M, Witzens-Harig M, Holte H, Thurner L, Borchmann P, Viardot A, Soekler M, Keller U, Schmidt C, Truemper L, Mahlberg R, Marks R, Hoeffkes HG, Metzner B, Dierlamm J, Frickhofen N, Haenel M, Neubauer A, Kneba M, Merli F, Tucci A, de Nully Brown P, Federico M, Lengfelder E, di Rocco A, Trappe R, Rosenwald A, Berdel C, Maisenhoelder M, Shpilberg O, Amam J, Christofyllakis K, Hartmann F, Murawski N, Stilgenbauer S, Nickelsen M, Wulf G, Glass B, Schmitz N, Altmann B, Loeffler M, Pfreundschuh M; FLYER Trial Investigators; German Lymphoma Alliance
Lancet 2019 Dec 21;394(10216):2271-2281. doi: 10.1016/S0140-6736(19)33008-9. PMID: 31868632
Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605Free PMC Article
Cheah CY, Wirth A, Seymour JF
Blood 2014 Jan 23;123(4):486-93. Epub 2013 Nov 26 doi: 10.1182/blood-2013-10-530659. PMID: 24282217
Vitolo U, Chiappella A, Ferreri AJ, Martelli M, Baldi I, Balzarotti M, Bottelli C, Conconi A, Gomez H, Lopez-Guillermo A, Martinelli G, Merli F, Novero D, Orsucci L, Pavone V, Ricardi U, Storti S, Gospodarowicz MK, Cavalli F, Sarris AH, Zucca E
J Clin Oncol 2011 Jul 10;29(20):2766-72. Epub 2011 Jun 6 doi: 10.1200/JCO.2010.31.4187. PMID: 21646602
Miedler JD, MacLennan GT
J Urol 2007 Dec;178(6):2645. Epub 2007 Oct 22 doi: 10.1016/j.juro.2007.09.012. PMID: 17945289

Clinical prediction guides

Zhang W, Yang P, Yang Y, Liu S, Xu Y, Wu C, Wang J, Liu C, Liu H, Li S, Huang W, Jing H
J Transl Med 2024 May 1;22(1):414. doi: 10.1186/s12967-024-05140-8. PMID: 38693538Free PMC Article
Mansoor A, Akhter A, Hamidi M, Roshan TM, Shabani-Rad MT, Stewart D
Anticancer Res 2023 Nov;43(11):4801-4807. doi: 10.21873/anticanres.16677. PMID: 37909960
Sun Y, Yan X, Zhao H, Cui Z, Wang Y, Sun S, Ning X, Xu H
Hematology 2022 Dec;27(1):1019-1025. doi: 10.1080/16078454.2022.2119345. PMID: 36066282
Wienand K, Chapuy B
Hematol Oncol 2021 Jun;39 Suppl 1:24-30. doi: 10.1002/hon.2847. PMID: 34105819
Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605Free PMC Article

Recent systematic reviews

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