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Eosinophilic Globules

MedGen UID:
1387422
Concept ID:
C4329792
Finding

Definition

A cellular droplet comprising fibrin degradation products or intracytoplasmic proteinaceous accumulations that can be stained by eosin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEosinophilic Globules

Professional guidelines

Recent clinical studies

Etiology

Zacher NC, Bailey EE, Kwong BY, Rieger KE
J Cutan Pathol 2022 Feb;49(2):176-182. Epub 2021 Oct 21 doi: 10.1111/cup.14144. PMID: 34617316
Rabban JT, Chan E, Mak J, Zaloudek C, Garg K
Am J Surg Pathol 2019 May;43(5):639-655. doi: 10.1097/PAS.0000000000001222. PMID: 30741757
Yang P, Cornejo KM, Sadow PM, Cheng L, Wang M, Xiao Y, Jiang Z, Oliva E, Jozwiak S, Nussbaum RL, Feldman AS, Paul E, Thiele EA, Yu JJ, Henske EP, Kwiatkowski DJ, Young RH, Wu CL
Am J Surg Pathol 2014 Jul;38(7):895-909. doi: 10.1097/PAS.0000000000000237. PMID: 24832166Free PMC Article
Berlingeri-Ramos AC, Morales-Burgos A, Sánchez JL, Nogales EM
Am J Dermatopathol 2010 May;32(3):267-275. doi: 10.1097/DAD.0b013e3181c52b99. PMID: 20098300
al-Nafussi AI, Hughes DE, Williams AR
Histopathology 1993 Dec;23(6):563-6. doi: 10.1111/j.1365-2559.1993.tb01244.x. PMID: 7508880

Diagnosis

Gallan AJ, Parilla M, Segal J, Ritterhouse L, Antic T
Am J Clin Pathol 2021 Apr 26;155(5):718-728. doi: 10.1093/ajcp/aqaa176. PMID: 33210135
Chan JK
Int J Surg Pathol 2014 Feb;22(1):12-32. Epub 2014 Jan 9 doi: 10.1177/1066896913517939. PMID: 24406626
Kim HJ, Kim MH, Kwon J, Kim JY, Park K, Ro JY
Ann Diagn Pathol 2012 Oct;16(5):411-5. Epub 2011 Jul 2 doi: 10.1016/j.anndiagpath.2011.04.002. PMID: 21724432
Murty OP, Mun K, Gopinath N, Wong KT
Am J Forensic Med Pathol 2008 Dec;29(4):364-7. doi: 10.1097/PAF.0b013e3181859ff7. PMID: 19259028
Arbuckle S, Weedon D
J Am Acad Dermatol 1982 Sep;7(3):324-7. doi: 10.1016/s0190-9622(82)80313-7. PMID: 6182169

Therapy

Greene SF, Nikula KJ, Poulin D, McInally K, Reynolds JA
Toxicol Pathol 2021 Feb;49(2):334-348. Epub 2020 Oct 12 doi: 10.1177/0192623320960420. PMID: 33043802
Noguchi K, Yokoo H, Nakanishi K, Kakisaka T, Tsuruga Y, Kamachi H, Matsushita M, Kamiyama T
World J Surg Oncol 2012 Apr 27;10:65. doi: 10.1186/1477-7819-10-65. PMID: 22540346Free PMC Article
Ljungström KG, Revenäs B, Smedegård G, Hedin H, Richter W, Saldeen T
Forensic Sci Int 1988 Sep;38(3-4):251-8. doi: 10.1016/0379-0738(88)90171-5. PMID: 2461334

Prognosis

Yao K, Duan Z, Feng J, Yan C, Qi X
Diagn Pathol 2022 Sep 24;17(1):72. doi: 10.1186/s13000-022-01252-1. PMID: 36153506Free PMC Article
Li H, Yang W, Tu X, Yu L, Huang D, Cheng Y, Chang B, Tang S, Ge H, Bao L, Zhou X, Bi R
Hum Pathol 2022 Aug;126:136-145. Epub 2022 May 31 doi: 10.1016/j.humpath.2022.05.016. PMID: 35659509
Gallan AJ, Parilla M, Segal J, Ritterhouse L, Antic T
Am J Clin Pathol 2021 Apr 26;155(5):718-728. doi: 10.1093/ajcp/aqaa176. PMID: 33210135
Reinhard H, Karamchandani DM
Biomed Res Int 2018;2018:2845291. Epub 2018 Jul 29 doi: 10.1155/2018/2845291. PMID: 30151376Free PMC Article
Ramnani D, Lindberg G, Gokaslan ST, Albores-Saavedra J
Ann Diagn Pathol 1999 Aug;3(4):220-6. doi: 10.1016/s1092-9134(99)80054-9. PMID: 10459048

Clinical prediction guides

Gournay M, Dugay F, Belaud-Rotureau MA, Peyronnet B, Mathieu R, Verhoest G, Bensalah K, Odent S, Denizeau P, Vigneau C, Morini A, Rioux-Leclercq N, Kammerer-Jacquet SF
Virchows Arch 2021 Apr;478(4):793-799. Epub 2020 Aug 26 doi: 10.1007/s00428-020-02910-9. PMID: 32845354
Toxicol Ind Health 2017 Jan;33(1):2-15. doi: 10.1177/0748233716670061. PMID: 28092230
Yang P, Cornejo KM, Sadow PM, Cheng L, Wang M, Xiao Y, Jiang Z, Oliva E, Jozwiak S, Nussbaum RL, Feldman AS, Paul E, Thiele EA, Yu JJ, Henske EP, Kwiatkowski DJ, Young RH, Wu CL
Am J Surg Pathol 2014 Jul;38(7):895-909. doi: 10.1097/PAS.0000000000000237. PMID: 24832166Free PMC Article
Chan JK
Int J Surg Pathol 2014 Feb;22(1):12-32. Epub 2014 Jan 9 doi: 10.1177/1066896913517939. PMID: 24406626
Kawai K, Senba M, Tsuchiyama H
APMIS 1988 Oct;96(10):911-6. doi: 10.1111/j.1699-0463.1988.tb00961.x. PMID: 2461212

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