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Glossopharyngeal motor neuropathy

MedGen UID:
155662
Concept ID:
C0751942
Disease or Syndrome
Synonyms: Glossopharyngeal Motor Neuropathies; Glossopharyngeal Motor Neuropathy; Motor Neuropathies, Glossopharyngeal; Motor Neuropathy, Glossopharyngeal
 
Monarch Initiative: MONDO:0004279

Definition

Diseases of the ninth cranial (glossopharyngeal) nerve or its nuclei in the medulla. The nerve may be injured by diseases affecting the lower brain stem, floor of the posterior fossa, jugular foramen, or the nerve's extracranial course. Clinical manifestations include loss of sensation from the pharynx, decreased salivation, and syncope. Glossopharyngeal neuralgia refers to a condition that features recurrent unilateral sharp pain in the tongue, angle of the jaw, external auditory meatus and throat that may be associated with syncope. Episodes may be triggered by cough, sneeze, swallowing, or pressure on the tragus of the ear. (Adams et al., Principles of Neurology, 6th ed, p1390) [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlossopharyngeal motor neuropathy

Professional guidelines

PubMed

Fisher R, Clarkson E
Dent Clin North Am 2024 Jan;68(1):121-131. Epub 2023 Aug 30 doi: 10.1016/j.cden.2023.07.010. PMID: 37951629
Yue WL, Zhang Y
Clin Otolaryngol 2013 Dec;38(6):533-5. doi: 10.1111/coa.12181. PMID: 24102955
Sarlani E, Balciunas BA, Grace EG
AACN Clin Issues 2005 Jul-Sep;16(3):333-46. doi: 10.1097/00044067-200507000-00007. PMID: 16082236

Recent clinical studies

Etiology

Papadopoulou M, Anastasakis S
BMJ Case Rep 2022 Jul 25;15(7) doi: 10.1136/bcr-2022-251033. PMID: 35878966Free PMC Article
Shaefer JR, Khawaja SN, Bavia PF
Dent Clin North Am 2018 Oct;62(4):665-682. Epub 2018 Aug 2 doi: 10.1016/j.cden.2018.06.001. PMID: 30189989
Chen J, Sindou M
Acta Neurochir (Wien) 2015 Feb;157(2):311-21; discussion 321. Epub 2014 Dec 21 doi: 10.1007/s00701-014-2302-7. PMID: 25526720
Tamaki T, Node Y, Saitoum N, Saigusa H, Yamazaki M, Morita A
Perspect Vasc Surg Endovasc Ther 2013 Dec;25(3-4):65-8. doi: 10.1177/1531003514525476. PMID: 24625858
Rey-Dios R, Cohen-Gadol AA
Neurosurg Focus 2013 Mar;34(3):E8. doi: 10.3171/2012.12.FOCUS12391. PMID: 23451790

Diagnosis

Allam AK, Larkin MB, Sharma H, Viswanathan A
Neurol Clin 2024 May;42(2):585-598. Epub 2024 Jan 12 doi: 10.1016/j.ncl.2023.12.011. PMID: 38575268
Christoforou J
Dent Clin North Am 2018 Oct;62(4):565-584. Epub 2018 Jul 31 doi: 10.1016/j.cden.2018.05.005. PMID: 30189983
Tepper SJ
Continuum (Minneap Minn) 2018 Aug;24(4, Headache):1157-1178. doi: 10.1212/CON.0000000000000637. PMID: 30074554
Hupp WS, Firriolo FJ
Dent Clin North Am 2013 Jul;57(3):481-95. Epub 2013 May 21 doi: 10.1016/j.cden.2013.04.009. PMID: 23809305
Blumenfeld A, Nikolskaya G
Curr Pain Headache Rep 2013 Jul;17(7):343. doi: 10.1007/s11916-013-0343-x. PMID: 23709235

Therapy

Reddy GD, Viswanathan A
Neurol Clin 2014 May;32(2):539-52. Epub 2013 Dec 28 doi: 10.1016/j.ncl.2013.11.008. PMID: 24703544
Hupp WS, Firriolo FJ
Dent Clin North Am 2013 Jul;57(3):481-95. Epub 2013 May 21 doi: 10.1016/j.cden.2013.04.009. PMID: 23809305
Rey-Dios R, Cohen-Gadol AA
Neurosurg Focus 2013 Mar;34(3):E8. doi: 10.3171/2012.12.FOCUS12391. PMID: 23451790
Hutchinson CD, Jardine DL, Hurrell M
Age Ageing 2008 Sep;37(5):602-4. Epub 2008 Jun 12 doi: 10.1093/ageing/afn105. PMID: 18556705
Scully Cbe C, Shotts R
Practitioner 2001 Jun;245(1623):539, 542-6, 548-9. PMID: 11436264

Prognosis

Tamaki T, Node Y, Saitoum N, Saigusa H, Yamazaki M, Morita A
Perspect Vasc Surg Endovasc Ther 2013 Dec;25(3-4):65-8. doi: 10.1177/1531003514525476. PMID: 24625858
Rey-Dios R, Cohen-Gadol AA
Neurosurg Focus 2013 Mar;34(3):E8. doi: 10.3171/2012.12.FOCUS12391. PMID: 23451790
Hutchinson CD, Jardine DL, Hurrell M
Age Ageing 2008 Sep;37(5):602-4. Epub 2008 Jun 12 doi: 10.1093/ageing/afn105. PMID: 18556705
Ozveren MF, Türe U
Neurosurg Focus 2004 Aug 15;17(2):E3. doi: 10.3171/foc.2004.17.2.3. PMID: 15329018
Kono I, Takashima T, Tsuda S, Ueda Y, Ijichi T, Fujita N, Araki K, Nakajima K
Acta Haematol 1994;92(3):157-9. doi: 10.1159/000204210. PMID: 7871958

Clinical prediction guides

Komatsu F, Kishore K, Sengupta R
Acta Neurochir (Wien) 2020 Nov;162(11):2833-2835. Epub 2020 Jun 18 doi: 10.1007/s00701-020-04456-w. PMID: 32556527
Taylor RJ, Lowe SR, Ellis N, Abdullah E, Patel S, Halstead LA
Laryngoscope 2019 Sep;129(9):2105-2111. Epub 2018 Dec 24 doi: 10.1002/lary.27678. PMID: 30582168
Tamaki T, Node Y, Saitoum N, Saigusa H, Yamazaki M, Morita A
Perspect Vasc Surg Endovasc Ther 2013 Dec;25(3-4):65-8. doi: 10.1177/1531003514525476. PMID: 24625858
Rainov NG, Heidecke V
Neurol Res 2003 Mar;25(2):157-61. doi: 10.1179/016164103101201328. PMID: 12635515
Evans WE, Mendelowitz DS, Liapis C, Wolfe V, Florence CL
Ann Surg 1982 Oct;196(4):461-4. doi: 10.1097/00000658-198210000-00009. PMID: 7125731Free PMC Article

Recent systematic reviews

Berckemeyer MA, Suarez-Meade P, Carcelen MFV, Ricci MD, Cheshire WP, Trifiletti DM, Middlebrooks EH, Quinones-Hinojosa A, Grewal SS
Neurosurg Rev 2023 Feb 2;46(1):47. doi: 10.1007/s10143-023-01948-y. PMID: 36725770
Vogrig A, Muñiz-Castrillo S, Joubert B, Picard G, Rogemond V, Skowron F, Egri M, Desestret V, Tilikete C, Psimaras D, Ducray F, Honnorat J
Neurology 2021 Feb 9;96(6):e866-e875. Epub 2020 Dec 14 doi: 10.1212/WNL.0000000000011340. PMID: 33318162
Spina A, Boari N, Gagliardi F, Bailo M, Morselli C, Iannaccone S, Mortini P
Neurosurg Rev 2019 Mar;42(1):31-38. Epub 2017 Jul 26 doi: 10.1007/s10143-017-0886-0. PMID: 28748271
Lu VM, Goyal A, Graffeo CS, Perry A, Jonker BP, Link MJ
World Neurosurg 2018 Dec;120:572-582.e7. Epub 2018 Sep 18 doi: 10.1016/j.wneu.2018.09.042. PMID: 30240868
Nisa L, Landis BN, Giger R, Leuchter I
J Voice 2013 Sep;27(5):636-41. Epub 2013 Jun 12 doi: 10.1016/j.jvoice.2013.02.011. PMID: 23769009

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