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Abnormal coronary artery morphology

MedGen UID:: 1612789
•Concept ID:: C4531298
•: Anatomical Abnormality

Synonyms:	coronary artery congenital malformation; Coronary artery congenital malformation

HPO:	HP:0006704
Monarch Initiative:	MONDO:0015203
Orphanet:	ORPHA1081

Definition

Any structural abnormality of the coronary arteries. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormal coronary artery morphology

Disorder of cardiovascular system
- Abnormality of the cardiovascular system
  - Abnormal cardiovascular system morphology
    - Abnormal vascular morphology
      - Abnormal blood vessel morphology
        Abnormal systemic arterial morphology
        Abnormal coronary artery morphology
        Abnormal coronary artery course
        Coronary artery fistula
        Coronary arteriovenous fistula
        Coronary cameral fistula
        Coronary-pulmonary artery fistula
        Myocardial bridging
        Abnormal coronary artery origin
        Absent left main coronary artery
        Anomalous coronary artery arising from the opposite sinus
        Coronary artery sandwich anomaly
        Anomalous origin of coronary artery from the pulmonary artery
        Anomalous origin of left coronary artery from the pulmonary artery
        Anomalous origin of right coronary artery from the pulmonary artery
        Anomalous origin of the left anterior descending artery from the pulmonary artery
        Anomalous origin of the circumflex artery from the right sinus of Valsalva
        Anomalous origin of the left circumflex artery from the right coronary artery
        Coronary ostial atresia
        Right coronary artery ostial atresia
        Separate origin of the left anterior descending and left circumflex artery
        Single coronary artery origin
        Congenital coronary artery aneurysm
        Coronary aneurysm
        Coronary artery calcification
        Coronary artery dissection
        Coronary artery stenosis
        Coronary restenosis
        Left Main Coronary Artery Stenosis
        Left Main Coronary Artery Stenosis, Percentage
        Proximal Left Anterior Descending Coronary Artery Stenosis
        Intimal thickening in the coronary arteries

Professional guidelines

PubMed

Causes, Angiographic Characteristics, and Management of Premature Myocardial Infarction: JACC State-of-the-Art Review.

Rallidis LS, Xenogiannis I, Brilakis ES, Bhatt DL
J Am Coll Cardiol 2022 Jun 21;79(24):2431-2449. doi: 10.1016/j.jacc.2022.04.015. PMID: 35710195

Triage, diagnosis and management of acute chest pain syndromes, atypical and high-risk subtypes of acute coronary artery syndromes.

Vrints CJ
Eur Heart J Acute Cardiovasc Care 2018 Oct;7(7):589-590. doi: 10.1177/2048872618810252. PMID: 30324826

Congenital anomalies of the thoracic aorta and its branches: pathophysiology, clinical course, and management.

Billig DM
Prog Cardiovasc Dis 1973 Jul-Aug;16(1):43-67. doi: 10.1016/0033-0620(73)90004-2. PMID: 4577245

See all (104)

Recent clinical studies

Etiology

Causes, Angiographic Characteristics, and Management of Premature Myocardial Infarction: JACC State-of-the-Art Review.

Rallidis LS, Xenogiannis I, Brilakis ES, Bhatt DL
J Am Coll Cardiol 2022 Jun 21;79(24):2431-2449. doi: 10.1016/j.jacc.2022.04.015. PMID: 35710195

Coronary venous anatomy and anomalies.

Sirajuddin A, Chen MY, White CS, Arai AE
J Cardiovasc Comput Tomogr 2020 Jan-Feb;14(1):80-86. Epub 2019 Aug 7 doi: 10.1016/j.jcct.2019.08.006. PMID: 31444098

Three-dimensional rotational angiography in congenital heart disease: Present status and evolving future.

Kang SL, Armstrong A, Krings G, Benson L
Congenit Heart Dis 2019 Nov;14(6):1046-1057. Epub 2019 Sep 4 doi: 10.1111/chd.12838. PMID: 31483574

Systematic review of patients presenting with suspected myocardial infarction and nonobstructive coronary arteries.

Pasupathy S, Air T, Dreyer RP, Tavella R, Beltrame JF
Circulation 2015 Mar 10;131(10):861-70. Epub 2015 Jan 13 doi: 10.1161/CIRCULATIONAHA.114.011201. PMID: 25587100

Letter: Diagonal ear-lobe crease and coronary artery sclerosis.

Lichtstein E, Chapman I, Gupta PK, Chadda KD, Smith H Jr, Schwartz I, Naik D
Ann Intern Med 1976 Sep;85(3):337-8. doi: 10.7326/0003-4819-85-3-337. PMID: 962224

See all (2584)

Diagnosis

Acquired Coronary Fenestration.

Hafiz AM, Perras M, Kakouros N
J Invasive Cardiol 2019 Dec;31(12):E396. PMID: 31786535

Primary-care management of patients with congenital anomalies of the coronary arteries.

Boris JR, Brothers JA
Cardiol Young 2015 Dec;25(8):1540-5. doi: 10.1017/S1047951115002127. PMID: 26675602

Kawasaki disease.

Newburger JW, Fulton DR
Curr Opin Pediatr 2004 Oct;16(5):508-14. doi: 10.1097/01.mop.0000137796.23813.64. PMID: 15367843

Update on myocardial bridging.

Möhlenkamp S, Hort W, Ge J, Erbel R
Circulation 2002 Nov 12;106(20):2616-22. doi: 10.1161/01.cir.0000038420.14867.7a. PMID: 12427660

Coronary artery anatomy and transposition of the great arteries.

Wernovsky G, Sanders SP
Coron Artery Dis 1993 Feb;4(2):148-57. doi: 10.1097/00019501-199302000-00005. PMID: 8269206

See all (3413)

Therapy

Causes, Angiographic Characteristics, and Management of Premature Myocardial Infarction: JACC State-of-the-Art Review.

Rallidis LS, Xenogiannis I, Brilakis ES, Bhatt DL
J Am Coll Cardiol 2022 Jun 21;79(24):2431-2449. doi: 10.1016/j.jacc.2022.04.015. PMID: 35710195

Three-dimensional rotational angiography in congenital heart disease: Present status and evolving future.

Kang SL, Armstrong A, Krings G, Benson L
Congenit Heart Dis 2019 Nov;14(6):1046-1057. Epub 2019 Sep 4 doi: 10.1111/chd.12838. PMID: 31483574

The Evidence on Estrogen, Progesterone, and Spontaneous Coronary Artery Dissection.

Tweet MS, Miller VM, Hayes SN
JAMA Cardiol 2019 May 1;4(5):403-404. doi: 10.1001/jamacardio.2019.0774. PMID: 30969320

Myocardial bridging.

Alegria JR, Herrmann J, Holmes DR Jr, Lerman A, Rihal CS
Eur Heart J 2005 Jun;26(12):1159-68. Epub 2005 Mar 11 doi: 10.1093/eurheartj/ehi203. PMID: 15764618

Kawasaki disease.

Newburger JW, Fulton DR
Curr Opin Pediatr 2004 Oct;16(5):508-14. doi: 10.1097/01.mop.0000137796.23813.64. PMID: 15367843

See all (952)

Prognosis

Causes, Angiographic Characteristics, and Management of Premature Myocardial Infarction: JACC State-of-the-Art Review.

Rallidis LS, Xenogiannis I, Brilakis ES, Bhatt DL
J Am Coll Cardiol 2022 Jun 21;79(24):2431-2449. doi: 10.1016/j.jacc.2022.04.015. PMID: 35710195

Systematic review of patients presenting with suspected myocardial infarction and nonobstructive coronary arteries.

Pasupathy S, Air T, Dreyer RP, Tavella R, Beltrame JF
Circulation 2015 Mar 10;131(10):861-70. Epub 2015 Jan 13 doi: 10.1161/CIRCULATIONAHA.114.011201. PMID: 25587100

Kawasaki disease.

Newburger JW, Fulton DR
Curr Opin Pediatr 2004 Oct;16(5):508-14. doi: 10.1097/01.mop.0000137796.23813.64. PMID: 15367843

Sudden cardiac death.

Virmani R, Burke AP, Farb A
Cardiovasc Pathol 2001 Nov-Dec;10(6):275-82. doi: 10.1016/s1054-8807(01)00108-9. PMID: 11755373

Coronary artery anatomy and transposition of the great arteries.

Wernovsky G, Sanders SP
Coron Artery Dis 1993 Feb;4(2):148-57. doi: 10.1097/00019501-199302000-00005. PMID: 8269206

See all (2264)

Clinical prediction guides

Coronary Optical Coherence Tomography and Cardiac Magnetic Resonance Imaging to Determine Underlying Causes of Myocardial Infarction With Nonobstructive Coronary Arteries in Women.

Reynolds HR, Maehara A, Kwong RY, Sedlak T, Saw J, Smilowitz NR, Mahmud E, Wei J, Marzo K, Matsumura M, Seno A, Hausvater A, Giesler C, Jhalani N, Toma C, Har B, Thomas D, Mehta LS, Trost J, Mehta PK, Ahmed B, Bainey KR, Xia Y, Shah B, Attubato M, Bangalore S, Razzouk L, Ali ZA, Merz NB, Park K, Hada E, Zhong H, Hochman JS
Circulation 2021 Feb 16;143(7):624-640. Epub 2020 Nov 14 doi: 10.1161/CIRCULATIONAHA.120.052008. PMID: 33191769 Free PMC Article

Three-dimensional rotational angiography in congenital heart disease: Present status and evolving future.

Kang SL, Armstrong A, Krings G, Benson L
Congenit Heart Dis 2019 Nov;14(6):1046-1057. Epub 2019 Sep 4 doi: 10.1111/chd.12838. PMID: 31483574

Coronary-pulmonary artery fistula in tetralogy of Fallot with pulmonary atresia.

Talwar S, Anderson RH, Keshri VK, Choudhary SK, Gulati GS, Airan B
Asian Cardiovasc Thorac Ann 2014 Oct;22(8):1003-9. Epub 2013 Nov 12 doi: 10.1177/0218492313505101. PMID: 24887892

Giant coronary sinus.

Nathani S, Parakh N, Chaturvedi V, Tyagi S
Tex Heart Inst J 2011;38(3):310-1. PMID: 21720482 Free PMC Article

Unroofing the diagnosis.

Cannavale G, Higgins CB, Ordovas KG
Int J Cardiovasc Imaging 2010 Dec;26(8):841-2. Epub 2010 Jul 8 doi: 10.1007/s10554-010-9667-3. PMID: 20614189

See all (1522)

Recent systematic reviews

Myocardial bridges: A meta-analysis.

Roberts W, Charles SM, Ang C, Holda MK, Walocha J, Lachman N, Tubbs RS, Loukas M
Clin Anat 2021 Jul;34(5):685-709. Epub 2021 Feb 22 doi: 10.1002/ca.23697. PMID: 33078444

Association Between Caliber of Retinal Vessels and Cardiovascular Disease: a Systematic Review and Meta-Analysis.

Guo S, Yin S, Tse G, Li G, Su L, Liu T
Curr Atheroscler Rep 2020 May 21;22(4):16. doi: 10.1007/s11883-020-0834-2. PMID: 32440852

Spontaneous coronary artery dissection and associated myocardial bridging: Current evidence from cohort study and case reports.

Tajrishi FZ, Ahmad A, Jamil A, Sharfaei S, Goudarzi S, Homayounieh F, Pitliya A, Kahe F, Chi G
Med Hypotheses 2019 Jul;128:50-53. Epub 2019 May 13 doi: 10.1016/j.mehy.2019.05.012. PMID: 31203908

Coronary-Pulmonary Artery Fistulas: A Systematic Review.

Verdini D, Vargas D, Kuo A, Ghoshhajra B, Kim P, Murillo H, Kirsch J, Lane M, Restrepo C
J Thorac Imaging 2016 Nov;31(6):380-390. doi: 10.1097/RTI.0000000000000232. PMID: 27768631

Systematic review of patients presenting with suspected myocardial infarction and nonobstructive coronary arteries.

Pasupathy S, Air T, Dreyer RP, Tavella R, Beltrame JF
Circulation 2015 Mar 10;131(10):861-70. Epub 2015 Jan 13 doi: 10.1161/CIRCULATIONAHA.114.011201. PMID: 25587100

See all (18)

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Abnormal coronary artery morphology

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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