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Nuclear sclerotic cataract

MedGen UID:
1618293
Concept ID:
C1112705
Disease or Syndrome
Synonym: Cataract, nuclear sclerotic
SNOMED CT: Nuclear sclerotic cataract (359766000)

Definition

A type of cataract that forms deep in the central zone (nucleus) of the lens. Nuclear cataracts are usually associated with aging. [from NCI]

Professional guidelines

PubMed

Chee SP, Wong MH, Jap A
Am J Ophthalmol 2017 Jan;173:7-15. Epub 2016 Sep 23 doi: 10.1016/j.ajo.2016.09.021. PMID: 27670621
Geerts L, Pertile G, van de Sompel W, Moreels T, Claes C
Bull Soc Belge Ophtalmol 2004;(293):7-15. PMID: 15510718

Recent clinical studies

Etiology

Vedachalam R, Yamini K, Venkatesh R, Kalpana N, Shivkumar C, Shekhar M, Haripriya A, Sathya R
Indian J Ophthalmol 2022 Jun;70(6):2153-2157. doi: 10.4103/ijo.IJO_544_22. PMID: 35648002Free PMC Article
Keyal K, Liao X, Liu G, Yang S, Wang F
Discov Med 2017 Dec;24(134):305-311. PMID: 29373808
Almony A, Holekamp NM, Bai F, Shui YB, Beebe D
Retina 2012 Mar;32(3):499-505. doi: 10.1097/IAE.0b013e31822529cf. PMID: 22392091
Pauleikhoff D, Koch JM
Curr Opin Ophthalmol 1995 Jun;6(3):51-6. doi: 10.1097/00055735-199506000-00009. PMID: 10150870
Brown NA, Hill AR
Br J Ophthalmol 1987 Jun;71(6):405-14. doi: 10.1136/bjo.71.6.405. PMID: 3620419Free PMC Article

Diagnosis

Chee SP, Weikert MP, Wallace R, De Francesco T, Ahmed I, Fram N, McCabe CM
J Cataract Refract Surg 2024 Nov 1;50(11):1191-1196. doi: 10.1097/j.jcrs.0000000000001544. PMID: 39446765
Praidou A, Jacob S, Irion L, Sivaraj R, Groenewald C, Coupland SE, Heimann H
BMC Cancer 2017 Jun 19;17(1):430. doi: 10.1186/s12885-017-3429-8. PMID: 28629380Free PMC Article
Congdon NG, Quigley HA, Hung PT, Wang TH, Ho TC
Acta Ophthalmol Scand 1996 Apr;74(2):113-9. doi: 10.1111/j.1600-0420.1996.tb00053.x. PMID: 8739673
Pauleikhoff D, Koch JM
Curr Opin Ophthalmol 1995 Jun;6(3):51-6. doi: 10.1097/00055735-199506000-00009. PMID: 10150870
O'Donnell FE Jr, Maumenee AE
Ophthalmic Surg 1980 Feb;11(2):99-101. PMID: 7366950

Therapy

Park SS, Tseng M, Mian Z, Moon JY, Shrivastava A
Graefes Arch Clin Exp Ophthalmol 2023 Aug;261(8):2307-2314. Epub 2023 Mar 16 doi: 10.1007/s00417-023-06027-y. PMID: 36929055Free PMC Article
Fram NR, McKee Y, Chang DF, Chee SP, Donaldson KE, Crandall DA, Al-Mohtaseb Z, Chen AJ
J Cataract Refract Surg 2023 Feb 1;49(2):221-222. doi: 10.1097/j.jcrs.0000000000001129. PMID: 36700891
Keyal K, Liao X, Liu G, Yang S, Wang F
Discov Med 2017 Dec;24(134):305-311. PMID: 29373808
Praidou A, Jacob S, Irion L, Sivaraj R, Groenewald C, Coupland SE, Heimann H
BMC Cancer 2017 Jun 19;17(1):430. doi: 10.1186/s12885-017-3429-8. PMID: 28629380Free PMC Article
Almony A, Holekamp NM, Bai F, Shui YB, Beebe D
Retina 2012 Mar;32(3):499-505. doi: 10.1097/IAE.0b013e31822529cf. PMID: 22392091

Prognosis

Fram NR, McKee Y, Chang DF, Chee SP, Donaldson KE, Crandall DA, Al-Mohtaseb Z, Chen AJ
J Cataract Refract Surg 2023 Feb 1;49(2):221-222. doi: 10.1097/j.jcrs.0000000000001129. PMID: 36700891
Praidou A, Jacob S, Irion L, Sivaraj R, Groenewald C, Coupland SE, Heimann H
BMC Cancer 2017 Jun 19;17(1):430. doi: 10.1186/s12885-017-3429-8. PMID: 28629380Free PMC Article
Okamoto Y, Okamoto F, Hiraoka T, Oshika T
Am J Ophthalmol 2014 Sep;158(3):544-9.e1. Epub 2014 May 27 doi: 10.1016/j.ajo.2014.05.018. PMID: 24874997
Holekamp NM, Shui YB, Beebe D
Am J Ophthalmol 2006 Jun;141(6):1027-32. doi: 10.1016/j.ajo.2006.01.016. PMID: 16765670
Cherfan GM, Michels RG, de Bustros S, Enger C, Glaser BM
Am J Ophthalmol 1991 Apr 15;111(4):434-8. doi: 10.1016/s0002-9394(14)72377-3. PMID: 2012145

Clinical prediction guides

Okamoto Y, Okamoto F, Hiraoka T, Oshika T
Am J Ophthalmol 2014 Sep;158(3):544-9.e1. Epub 2014 May 27 doi: 10.1016/j.ajo.2014.05.018. PMID: 24874997
Almony A, Holekamp NM, Bai F, Shui YB, Beebe D
Retina 2012 Mar;32(3):499-505. doi: 10.1097/IAE.0b013e31822529cf. PMID: 22392091
Chen SN, Lin KK, Chao AN, Kuo YH, Ho JD
J Cataract Refract Surg 2003 May;29(5):983-8. doi: 10.1016/s0886-3350(02)01700-5. PMID: 12781287
Nordlund ML, Sugar A, Moroi SE
J Cataract Refract Surg 2000 Jul;26(7):1035-40. doi: 10.1016/s0886-3350(00)00433-8. PMID: 10946196
Melberg NS, Thomas MA
Ophthalmology 1995 Oct;102(10):1466-71. doi: 10.1016/s0161-6420(95)30844-5. PMID: 9097793

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