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Nuclear Cataract Grade 3

MedGen UID:
1620804
Concept ID:
C4525725
Disease or Syndrome

Definition

A stage of nuclear sclerotic cataract marked by pronounced yellowing and sclerosis of the lens nucleus. (Modified LOCS II) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNuclear Cataract Grade 3

Professional guidelines

PubMed

Hernando-Calvo A, Malone E, Day D, Prawira A, Weinreb I, Yang SYC, Wong H, Rodriguez A, Jennings S, Eliason A, Wang L, Spreafico A, Siu LL, Hansen AR
Cancer Med 2023 Oct;12(20):20299-20310. Epub 2023 Oct 11 doi: 10.1002/cam4.6589. PMID: 37818869Free PMC Article
Chee SP, Wong MH, Jap A
Am J Ophthalmol 2017 Jan;173:7-15. Epub 2016 Sep 23 doi: 10.1016/j.ajo.2016.09.021. PMID: 27670621

Recent clinical studies

Etiology

Patel C, Tan Y, Nygaard S, Guo B, Carrillo C, Burgess J, Souksamone K, Nouansavanh KO, Casson R
Ophthalmic Epidemiol 2023 Feb;30(1):57-65. Epub 2022 Feb 3 doi: 10.1080/09286586.2022.2028294. PMID: 35112939
Cai L, Ma D, Xu X, Han X, Qiu X, Lu Y, Yang J
J Cataract Refract Surg 2022 Dec 1;48(12):1381-1387. doi: 10.1097/j.jcrs.0000000000000998. PMID: 36449671
Menapace R, Schartmüller D, Röggla V, Reiter GS, Leydolt C, Schwarzenbacher L
Acta Ophthalmol 2022 Mar;100(2):e414-e422. Epub 2021 Sep 20 doi: 10.1111/aos.14983. PMID: 34543523Free PMC Article
Michael R, Pareja-Aricò L, Rauscher FG, Barraquer RI
Ophthalmic Res 2019;62(3):157-165. Epub 2019 Mar 28 doi: 10.1159/000496865. PMID: 30921809
Skalicky SE, Martin KR, Fenwick E, Crowston JG, Goldberg I, McCluskey P
Clin Exp Ophthalmol 2015 May-Jun;43(4):335-41. Epub 2014 Oct 30 doi: 10.1111/ceo.12454. PMID: 25294739

Diagnosis

Katipoğlu Z, Turan M
Int Ophthalmol 2024 Feb 7;44(1):26. doi: 10.1007/s10792-024-03001-3. PMID: 38326697
Ganesh S, Brar S, Wadhokar S
J Cataract Refract Surg 2024 Jun 1;50(6):572-577. doi: 10.1097/j.jcrs.0000000000001408. PMID: 38270508Free PMC Article
Shimizu E, Tanji M, Nakayama S, Ishikawa T, Agata N, Yokoiwa R, Nishimura H, Khemlani RJ, Sato S, Hanyuda A, Sato Y
Sci Rep 2023 Dec 12;13(1):22046. doi: 10.1038/s41598-023-49563-7. PMID: 38086904Free PMC Article
Eom Y, Suh YW, Kim SW, Lee YJ, Jeon HS, Lee SY, Lee IH, Song JS, Kim HM
Graefes Arch Clin Exp Ophthalmol 2023 Jul;261(7):1923-1932. Epub 2023 Feb 24 doi: 10.1007/s00417-023-05999-1. PMID: 36826601
Sánchez RF, García-Guerra CE, Martínez-Roda JA, de Paul AG, Issolio LA, Pujol J
Curr Eye Res 2022 Mar;47(3):391-398. Epub 2021 Nov 18 doi: 10.1080/02713683.2021.2002908. PMID: 34738850

Therapy

Ganesh S, Brar S, Wadhokar S
J Cataract Refract Surg 2024 Jun 1;50(6):572-577. doi: 10.1097/j.jcrs.0000000000001408. PMID: 38270508Free PMC Article
Cai L, Ma D, Xu X, Han X, Qiu X, Lu Y, Yang J
J Cataract Refract Surg 2022 Dec 1;48(12):1381-1387. doi: 10.1097/j.jcrs.0000000000000998. PMID: 36449671
Singh R, Sharma AK, Katiyar V, Kumar G, Gupta SK
Indian J Ophthalmol 2022 Nov;70(11):3904-3909. doi: 10.4103/ijo.IJO_1304_22. PMID: 36308124Free PMC Article
Menapace R, Schartmüller D, Röggla V, Reiter GS, Leydolt C, Schwarzenbacher L
Acta Ophthalmol 2022 Mar;100(2):e414-e422. Epub 2021 Sep 20 doi: 10.1111/aos.14983. PMID: 34543523Free PMC Article
Lyu D, Shen Z, Zhang L, Qin Z, Ni S, Wang W, Zhu Y, Yao K
Am J Ophthalmol 2020 May;213:283-292. Epub 2019 Dec 27 doi: 10.1016/j.ajo.2019.12.017. PMID: 31887280

Prognosis

Loomis SJ, Klein AP, Lee KE, Chen F, Bomotti S, Truitt B, Iyengar SK, Klein R, Klein BEK, Duggal P
Ophthalmic Epidemiol 2018 Jun;25(3):215-219. Epub 2017 Nov 28 doi: 10.1080/09286586.2017.1406122. PMID: 29182452Free PMC Article
Kanthan GL, Mitchell P, Rochtchina E, Cumming RG, Wang JJ
Clin Exp Ophthalmol 2014 May-Jun;42(4):347-53. Epub 2013 Oct 11 doi: 10.1111/ceo.12206. PMID: 24024555
Kanthan GL, Mitchell P, Burlutsky G, Rochtchina E, Wang JJ
Am J Ophthalmol 2013 Jan;155(1):83-88.e1. Epub 2012 Oct 2 doi: 10.1016/j.ajo.2012.07.002. PMID: 23036566
Tan AG, Mitchell P, Rochtchina E, Hong T, Cumming RG, Wang JJ
Eye (Lond) 2012 Apr;26(4):568-75. Epub 2011 Dec 23 doi: 10.1038/eye.2011.349. PMID: 22193877Free PMC Article
Younan C, Mitchell P, Cumming RG, Rochtchina E, Wang JJ
Invest Ophthalmol Vis Sci 2002 Dec;43(12):3625-32. PMID: 12454028

Clinical prediction guides

Ganesh S, Brar S, Wadhokar S
J Cataract Refract Surg 2024 Jun 1;50(6):572-577. doi: 10.1097/j.jcrs.0000000000001408. PMID: 38270508Free PMC Article
Sánchez RF, García-Guerra CE, Martínez-Roda JA, de Paul AG, Issolio LA, Pujol J
Curr Eye Res 2022 Mar;47(3):391-398. Epub 2021 Nov 18 doi: 10.1080/02713683.2021.2002908. PMID: 34738850
Chen Y, Nondahl DM, Schubert CR, Klein BE, Klein R, Cruickshanks KJ
Ophthalmic Epidemiol 2017 Apr;24(2):111-115. Epub 2017 Jan 31 doi: 10.1080/09286586.2016.1259640. PMID: 28139160Free PMC Article
Skalicky SE, Martin KR, Fenwick E, Crowston JG, Goldberg I, McCluskey P
Clin Exp Ophthalmol 2015 May-Jun;43(4):335-41. Epub 2014 Oct 30 doi: 10.1111/ceo.12454. PMID: 25294739
Chylack LT Jr, Wolfe JK, Friend J, Khu PM, Singer DM, McCarthy D, del Carmen J, Rosner B
Optom Vis Sci 1993 Nov;70(11):886-95. doi: 10.1097/00006324-199311000-00005. PMID: 8302524

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