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Recurrent Malignant Female Reproductive System Neoplasm

MedGen UID:
1667272
•Concept ID:
C4725803
•
Neoplastic Process

Definition

The reemergence of a malignant female reproductive system neoplasm after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Malignant Female Reproductive System Neoplasm

Professional guidelines

PubMed

Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup.
Vergote I, Gonzalez-Martin A, Lorusso D, Gourley C, Mirza MR, Kurtz JE, Okamoto A, Moore K, Kridelka F, McNeish I, Reuss A, Votan B, du Bois A, Mahner S, Ray-Coquard I, Kohn EC, Berek JS, Tan DSP, Colombo N, Zang R, Concin N, O'Donnell D, Rauh-Hain A, Herrington CS, Marth C, Poveda A, Fujiwara K, Stuart GCE, Oza AM, Bookman MA; participants of the 6th Gynecologic Cancer InterGroup (GCIG) Ovarian Cancer Consensus Conference on Clinical Research
Lancet Oncol 2022 Aug;23(8):e374-e384. doi: 10.1016/S1470-2045(22)00139-5. PMID: 35901833Free PMC Article
NRG Oncology/RTOG Consensus Guidelines for Delineation of Clinical Target Volume for Intensity Modulated Pelvic Radiation Therapy in Postoperative Treatment of Endometrial and Cervical Cancer: An Update.
Small W Jr, Bosch WR, Harkenrider MM, Strauss JB, Abu-Rustum N, Albuquerque KV, Beriwal S, Creutzberg CL, Eifel PJ, Erickson BA, Fyles AW, Hentz CL, Jhingran A, Klopp AH, Kunos CA, Mell LK, Portelance L, Powell ME, Viswanathan AN, Yacoub JH, Yashar CM, Winter KA, Gaffney DK
Int J Radiat Oncol Biol Phys 2021 Feb 1;109(2):413-424. Epub 2020 Sep 6 doi: 10.1016/j.ijrobp.2020.08.061. PMID: 32905846Free PMC Article
ESMO-ESGO consensus conference recommendations on ovarian cancer: pathology and molecular biology, early and advanced stages, borderline tumours and recurrent disease†.
Colombo N, Sessa C, du Bois A, Ledermann J, McCluggage WG, McNeish I, Morice P, Pignata S, Ray-Coquard I, Vergote I, Baert T, Belaroussi I, Dashora A, Olbrecht S, Planchamp F, Querleu D; ESMO-ESGO Ovarian Cancer Consensus Conference Working Group
Ann Oncol 2019 May 1;30(5):672-705. doi: 10.1093/annonc/mdz062. PMID: 31046081

Recent clinical studies

Etiology

Uterine sarcomas and rare uterine mesenchymal tumors with malignant potential. Diagnostic guidelines of the French Sarcoma Group and the Rare Gynecological Tumors Group.
Croce S, Devouassoux-Shisheboran M, Pautier P, Ray-Coquard I, Treilleux I, Neuville A, Arnould L, Just PA, Belda MALF, Averous G, Leroux A, Mery E, Loussouarn D, Weinbreck N, Le Guellec S, Mishellany F, Morice P, Guyon F, Genestie C
Gynecol Oncol 2022 Nov;167(2):373-389. Epub 2022 Sep 14 doi: 10.1016/j.ygyno.2022.07.031. PMID: 36114030
The role of molecular tests for adjuvant and post-surgical treatment in gynaecological cancers.
Wijaya ST, Ngoi NY, Tan DS
Best Pract Res Clin Obstet Gynaecol 2022 Jan;78:14-35. Epub 2021 Aug 4 doi: 10.1016/j.bpobgyn.2021.06.003. PMID: 34456153
Surgical challenges in the treatment of perimenopausal and postmenopausal endometriosis.
Ozyurek ES, Yoldemir T, Kalkan U
Climacteric 2018 Aug;21(4):385-390. Epub 2018 Mar 1 doi: 10.1080/13697137.2018.1439913. PMID: 29493295
Quantitative Assessment of Gynecologic Malignancies.
Tripathy S, Parida GK, Kumar R
PET Clin 2018 Apr;13(2):269-288. Epub 2018 Feb 3 doi: 10.1016/j.cpet.2017.11.010. PMID: 29482754
Lymphocele: prevalence and management in gynecological malignancies.
Weinberger V, Cibula D, Zikan M
Expert Rev Anticancer Ther 2014 Mar;14(3):307-17. Epub 2014 Feb 3 doi: 10.1586/14737140.2014.866043. PMID: 24483760

Diagnosis

Sentinel lymphatic mapping for gynecologic malignancies.
Hari AY, Tewari KS
Curr Opin Obstet Gynecol 2023 Feb 1;35(1):43-53. doi: 10.1097/GCO.0000000000000841. PMID: 36595648
Gynecologic cancer in pregnancy.
Korenaga TK, Tewari KS
Gynecol Oncol 2020 Jun;157(3):799-809. Epub 2020 Apr 5 doi: 10.1016/j.ygyno.2020.03.015. PMID: 32268951Free PMC Article
Gynecological neoplasms associated with paraneoplastic hypercalcemia.
Lim D, Oliva E
Semin Diagn Pathol 2019 Jul;36(4):246-259. Epub 2019 Feb 1 doi: 10.1053/j.semdp.2019.01.003. PMID: 30772079
Quantitative Assessment of Gynecologic Malignancies.
Tripathy S, Parida GK, Kumar R
PET Clin 2018 Apr;13(2):269-288. Epub 2018 Feb 3 doi: 10.1016/j.cpet.2017.11.010. PMID: 29482754
An update on post-treatment surveillance and diagnosis of recurrence in women with gynecologic malignancies: Society of Gynecologic Oncology (SGO) recommendations.
Salani R, Khanna N, Frimer M, Bristow RE, Chen LM
Gynecol Oncol 2017 Jul;146(1):3-10. Epub 2017 Mar 31 doi: 10.1016/j.ygyno.2017.03.022. PMID: 28372871

Therapy

PARP Inhibitors in Newly Diagnosed and Recurrent Ovarian Cancer.
Giannini A, Di Dio C, Di Donato V, D'oria O, Salerno MG, Capalbo G, Cuccu I, Perniola G, Muzii L, Bogani G
Am J Clin Oncol 2023 Sep 1;46(9):414-419. Epub 2023 Jun 12 doi: 10.1097/COC.0000000000001024. PMID: 37314974
Advances in antibody-drug conjugates for gynecologic malignancies.
Tymon-Rosario J, Gorman M, Richardson DL, Washington C, Santin AD
Curr Opin Obstet Gynecol 2023 Feb 1;35(1):6-14. Epub 2022 Dec 8 doi: 10.1097/GCO.0000000000000838. PMID: 36484278
Targeted therapies in gynecological cancers: a comprehensive review of clinical evidence.
Wang Q, Peng H, Qi X, Wu M, Zhao X
Signal Transduct Target Ther 2020 Jul 29;5(1):137. doi: 10.1038/s41392-020-0199-6. PMID: 32728057Free PMC Article
Primary cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy (HIPEC) for FIGO stage III epithelial ovarian cancer: OVHIPEC-2, a phase III randomized clinical trial.
Koole S, van Stein R, Sikorska K, Barton D, Perrin L, Brennan D, Zivanovic O, Mosgaard BJ, Fagotti A, Colombo PE, Sonke G, Driel WJV; OVHIPEC-2 Steering Committee and the Dutch OVHIPEC group
Int J Gynecol Cancer 2020 Jun;30(6):888-892. Epub 2020 Mar 23 doi: 10.1136/ijgc-2020-001231. PMID: 32205449Free PMC Article
Systemic therapy in cervical cancer: 30 years in review.
Liontos M, Kyriazoglou A, Dimitriadis I, Dimopoulos MA, Bamias A
Crit Rev Oncol Hematol 2019 May;137:9-17. Epub 2019 Feb 28 doi: 10.1016/j.critrevonc.2019.02.009. PMID: 31014518

Prognosis

Sentinel lymphatic mapping for gynecologic malignancies.
Hari AY, Tewari KS
Curr Opin Obstet Gynecol 2023 Feb 1;35(1):43-53. doi: 10.1097/GCO.0000000000000841. PMID: 36595648
Obesity, weight loss and gynecologic neoplasms: a narrative review.
Halpern B, Mendes TB
Women Health 2022 May-Jun;62(5):372-383. Epub 2022 May 22 doi: 10.1080/03630242.2022.2066747. PMID: 35603570
Gynecologic cancer in pregnancy.
Korenaga TK, Tewari KS
Gynecol Oncol 2020 Jun;157(3):799-809. Epub 2020 Apr 5 doi: 10.1016/j.ygyno.2020.03.015. PMID: 32268951Free PMC Article
Quantitative Assessment of Gynecologic Malignancies.
Tripathy S, Parida GK, Kumar R
PET Clin 2018 Apr;13(2):269-288. Epub 2018 Feb 3 doi: 10.1016/j.cpet.2017.11.010. PMID: 29482754
Gynecologic malignancies.
Whitcomb BP
Surg Clin North Am 2008 Apr;88(2):301-17, vi. doi: 10.1016/j.suc.2008.01.004. PMID: 18381115

Clinical prediction guides

Uterine sarcomas and rare uterine mesenchymal tumors with malignant potential. Diagnostic guidelines of the French Sarcoma Group and the Rare Gynecological Tumors Group.
Croce S, Devouassoux-Shisheboran M, Pautier P, Ray-Coquard I, Treilleux I, Neuville A, Arnould L, Just PA, Belda MALF, Averous G, Leroux A, Mery E, Loussouarn D, Weinbreck N, Le Guellec S, Mishellany F, Morice P, Guyon F, Genestie C
Gynecol Oncol 2022 Nov;167(2):373-389. Epub 2022 Sep 14 doi: 10.1016/j.ygyno.2022.07.031. PMID: 36114030
Updates in uterine artery embolization for leiomyomas.
Kim A, Arabkhazaeli M, Ulrich A, Lerner V, Shin JH
Curr Opin Obstet Gynecol 2020 Aug;32(4):269-276. doi: 10.1097/GCO.0000000000000635. PMID: 32487798
FDG-PET Imaging in Cervical Cancer.
Gandy N, Arshad MA, Park WE, Rockall AG, Barwick TD
Semin Nucl Med 2019 Nov;49(6):461-470. Epub 2019 Jun 24 doi: 10.1053/j.semnuclmed.2019.06.007. PMID: 31630730
Surgical challenges in the treatment of perimenopausal and postmenopausal endometriosis.
Ozyurek ES, Yoldemir T, Kalkan U
Climacteric 2018 Aug;21(4):385-390. Epub 2018 Mar 1 doi: 10.1080/13697137.2018.1439913. PMID: 29493295
Quantitative Assessment of Gynecologic Malignancies.
Tripathy S, Parida GK, Kumar R
PET Clin 2018 Apr;13(2):269-288. Epub 2018 Feb 3 doi: 10.1016/j.cpet.2017.11.010. PMID: 29482754

Recent systematic reviews

Systematic review and meta-analysis of prediction models used in cervical cancer.
Jha AK, Mithun S, Sherkhane UB, Jaiswar V, Osong B, Purandare N, Kannan S, Prabhash K, Gupta S, Vanneste B, Rangarajan V, Dekker A, Wee L
Artif Intell Med 2023 May;139:102549. Epub 2023 Apr 11 doi: 10.1016/j.artmed.2023.102549. PMID: 37100501
Hyperthermic intraperitoneal chemotherapy (HIPEC) for the management of primary advanced and recurrent ovarian cancer: a systematic review and meta-analysis of randomized trials.
Filis P, Mauri D, Markozannes G, Tolia M, Filis N, Tsilidis K
ESMO Open 2022 Oct;7(5):100586. Epub 2022 Sep 16 doi: 10.1016/j.esmoop.2022.100586. PMID: 36116421Free PMC Article
Role of human papillomavirus (HPV) vaccination on HPV infection and recurrence of HPV related disease after local surgical treatment: systematic review and meta-analysis.
Kechagias KS, Kalliala I, Bowden SJ, Athanasiou A, Paraskevaidi M, Paraskevaidis E, Dillner J, Nieminen P, Strander B, Sasieni P, Veroniki AA, Kyrgiou M
BMJ 2022 Aug 3;378:e070135. doi: 10.1136/bmj-2022-070135. PMID: 35922074Free PMC Article
ESGO/ESTRO/ESP Guidelines for the management of patients with endometrial carcinoma.
Concin N, Creutzberg CL, Vergote I, Cibula D, Mirza MR, Marnitz S, Ledermann JA, Bosse T, Chargari C, Fagotti A, Fotopoulou C, González-Martín A, Lax SF, Lorusso D, Marth C, Morice P, Nout RA, O'Donnell DE, Querleu D, Raspollini MR, Sehouli J, Sturdza AE, Taylor A, Westermann AM, Wimberger P, Colombo N, Planchamp F, Matias-Guiu X
Virchows Arch 2021 Feb;478(2):153-190. doi: 10.1007/s00428-020-03007-z. PMID: 33604759
Epidemiology of uterine fibroids: a systematic review.
Stewart EA, Cookson CL, Gandolfo RA, Schulze-Rath R
BJOG 2017 Sep;124(10):1501-1512. Epub 2017 May 13 doi: 10.1111/1471-0528.14640. PMID: 28296146

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