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Chronic Ocular Graft Versus Host Disease

MedGen UID:
1685703
•Concept ID:
C5203918
•
Disease or Syndrome

Definition

Chronic graft versus host disease occurring in the eye. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic Ocular Graft Versus Host Disease

Professional guidelines

PubMed

Safety and efficacy of intense pulsed light in the treatment of severe chronic ocular graft-versus-host disease.
Wang H, Yin X, Li Y, Zhang Z, Zhao K, Hu F, Liu Q, Lu Q, Wang Y, Zhang L, Jia H, Han J, Guo J, Li M
Ocul Surf 2023 Oct;30:276-285. Epub 2023 Oct 7 doi: 10.1016/j.jtos.2023.10.002. PMID: 37813151
Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria.
Ogawa Y, Dana R, Kim S, Jain S, Rosenblatt MI, Perez VL, Clayton JA, Alves M, Rocha EM, Amparo F, Seo KY, Wang Y, Shen J, Oh JY, Vanathi M, Nair S, Na KS, Riemens A, Sippel K, Soifer M, Wang S, Trindade M, Kim MK, Yoon CH, Yagi R, Hiratsuka R, Ogawa M, Shimizu E, Sato Y, Pflugfelder S, Tsubota K
Ocul Surf 2022 Oct;26:200-208. Epub 2022 Sep 18 doi: 10.1016/j.jtos.2022.09.002. PMID: 36130695
A single institute validation study comparing the international chronic ocular graft-versus-host disease consensus group diagnostic criteria with clinical parameters.
Hiratsuka R, Shimizu E, Yamane M, Yazu H, Sato S, Fukui M, Mukai S, Uchino M, Kamoi M, Tatematsu Y, Saijo Y, Negishi K, Tsubota K, Ogawa Y
Ocul Surf 2022 Apr;24:12-14. Epub 2021 Dec 18 doi: 10.1016/j.jtos.2021.12.009. PMID: 34933116

Recent clinical studies

Etiology

Delayed diagnosis of ocular graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Liao Y, Zhao W, Yang J, Li J, Chen J, Chen Z, Jin L, Li L, Huang F, Liang L
Ocul Surf 2024 Oct;34:1-8. Epub 2024 May 29 doi: 10.1016/j.jtos.2024.05.002. PMID: 38821405
Safety and efficacy of intense pulsed light in the treatment of severe chronic ocular graft-versus-host disease.
Wang H, Yin X, Li Y, Zhang Z, Zhao K, Hu F, Liu Q, Lu Q, Wang Y, Zhang L, Jia H, Han J, Guo J, Li M
Ocul Surf 2023 Oct;30:276-285. Epub 2023 Oct 7 doi: 10.1016/j.jtos.2023.10.002. PMID: 37813151
Alteration of Meibum Lipidomics Profiling in Patients With Chronic Ocular Graft-Versus-Host Disease.
Zhao W, Yang J, Liao Y, Yang B, Lin S, Liu R, Liang L
Invest Ophthalmol Vis Sci 2023 Sep 1;64(12):35. doi: 10.1167/iovs.64.12.35. PMID: 37733365Free PMC Article
Biomarkers in Ocular Graft-Versus-Host Disease: Implications for the Involvement of B Cells.
Shen Z, Ma J, Peng R, Hu B, Zhao Y, Liu S, Hong J
Transplant Cell Ther 2022 Nov;28(11):749.e1-749.e7. Epub 2022 Jul 29 doi: 10.1016/j.jtct.2022.07.023. PMID: 35914728
A single institute validation study comparing the international chronic ocular graft-versus-host disease consensus group diagnostic criteria with clinical parameters.
Hiratsuka R, Shimizu E, Yamane M, Yazu H, Sato S, Fukui M, Mukai S, Uchino M, Kamoi M, Tatematsu Y, Saijo Y, Negishi K, Tsubota K, Ogawa Y
Ocul Surf 2022 Apr;24:12-14. Epub 2021 Dec 18 doi: 10.1016/j.jtos.2021.12.009. PMID: 34933116

Diagnosis

Delayed diagnosis of ocular graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Liao Y, Zhao W, Yang J, Li J, Chen J, Chen Z, Jin L, Li L, Huang F, Liang L
Ocul Surf 2024 Oct;34:1-8. Epub 2024 May 29 doi: 10.1016/j.jtos.2024.05.002. PMID: 38821405
Safety and efficacy of intense pulsed light in the treatment of severe chronic ocular graft-versus-host disease.
Wang H, Yin X, Li Y, Zhang Z, Zhao K, Hu F, Liu Q, Lu Q, Wang Y, Zhang L, Jia H, Han J, Guo J, Li M
Ocul Surf 2023 Oct;30:276-285. Epub 2023 Oct 7 doi: 10.1016/j.jtos.2023.10.002. PMID: 37813151
Biomarkers in Ocular Graft-Versus-Host Disease: Implications for the Involvement of B Cells.
Shen Z, Ma J, Peng R, Hu B, Zhao Y, Liu S, Hong J
Transplant Cell Ther 2022 Nov;28(11):749.e1-749.e7. Epub 2022 Jul 29 doi: 10.1016/j.jtct.2022.07.023. PMID: 35914728
A single institute validation study comparing the international chronic ocular graft-versus-host disease consensus group diagnostic criteria with clinical parameters.
Hiratsuka R, Shimizu E, Yamane M, Yazu H, Sato S, Fukui M, Mukai S, Uchino M, Kamoi M, Tatematsu Y, Saijo Y, Negishi K, Tsubota K, Ogawa Y
Ocul Surf 2022 Apr;24:12-14. Epub 2021 Dec 18 doi: 10.1016/j.jtos.2021.12.009. PMID: 34933116
Prevalence and Risk Factors Associated With Corneal Perforation in Chronic Ocular Graft-Versus-Host-Disease.
Sinha S, Singh RB, Dohlman TH, Taketani Y, Yin J, Dana R
Cornea 2021 Jul 1;40(7):877-882. doi: 10.1097/ICO.0000000000002526. PMID: 32947414

Therapy

Delayed diagnosis of ocular graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Liao Y, Zhao W, Yang J, Li J, Chen J, Chen Z, Jin L, Li L, Huang F, Liang L
Ocul Surf 2024 Oct;34:1-8. Epub 2024 May 29 doi: 10.1016/j.jtos.2024.05.002. PMID: 38821405
Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease.
Gehlsen U, Stern ME, Franklin J, Tahmaz V, Hallek M, Holtick U, Scheid C, Steven P
Transplant Cell Ther 2022 Nov;28(11):782.e1-782.e7. Epub 2022 Jul 31 doi: 10.1016/j.jtct.2022.07.027. PMID: 35921986
Prevalence of neurotrophic keratopathy in patients with chronic ocular graft-versus-host disease.
Singh RB, Yuksel E, Sinha S, Wang S, Taketani Y, Luznik Z, Yin J, Dohlman TH, Dana R
Ocul Surf 2022 Oct;26:13-18. Epub 2022 Jul 16 doi: 10.1016/j.jtos.2022.07.001. PMID: 35843560
Outcomes and complications of cataract surgery in patients with chronic ocular graft-versus-host-disease-a multicenter, retrospective analysis.
Gehlsen U, Faust C, Blecha C, Dietrich-Ntoukas T, Eberwein P, Issleib S, Meyer-Ter-Vehn T, Braun R, Westekemper H, Steven P
Graefes Arch Clin Exp Ophthalmol 2022 Aug;260(8):2613-2622. Epub 2022 Mar 7 doi: 10.1007/s00417-022-05613-w. PMID: 35254513Free PMC Article
Prevalence and Risk Factors Associated With Corneal Perforation in Chronic Ocular Graft-Versus-Host-Disease.
Sinha S, Singh RB, Dohlman TH, Taketani Y, Yin J, Dana R
Cornea 2021 Jul 1;40(7):877-882. doi: 10.1097/ICO.0000000000002526. PMID: 32947414

Prognosis

Epidemiology and risk factors for the development of cicatrizing conjunctivitis in chronic ocular graft-versus-host disease.
Kantor NB, Sepulveda-Beltran PA, Valdés-Arias D, Locatelli EVT, Mulpuri L, Gunawardene AN, Amescua G, Perez VL, Tonk R, Wang T, Galor A
Ocul Surf 2024 Oct;34:341-347. Epub 2024 Sep 12 doi: 10.1016/j.jtos.2024.09.002. PMID: 39276859Free PMC Article
Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria.
Ogawa Y, Dana R, Kim S, Jain S, Rosenblatt MI, Perez VL, Clayton JA, Alves M, Rocha EM, Amparo F, Seo KY, Wang Y, Shen J, Oh JY, Vanathi M, Nair S, Na KS, Riemens A, Sippel K, Soifer M, Wang S, Trindade M, Kim MK, Yoon CH, Yagi R, Hiratsuka R, Ogawa M, Shimizu E, Sato Y, Pflugfelder S, Tsubota K
Ocul Surf 2022 Oct;26:200-208. Epub 2022 Sep 18 doi: 10.1016/j.jtos.2022.09.002. PMID: 36130695
Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease.
Gehlsen U, Stern ME, Franklin J, Tahmaz V, Hallek M, Holtick U, Scheid C, Steven P
Transplant Cell Ther 2022 Nov;28(11):782.e1-782.e7. Epub 2022 Jul 31 doi: 10.1016/j.jtct.2022.07.027. PMID: 35921986
Biomarkers in Ocular Graft-Versus-Host Disease: Implications for the Involvement of B Cells.
Shen Z, Ma J, Peng R, Hu B, Zhao Y, Liu S, Hong J
Transplant Cell Ther 2022 Nov;28(11):749.e1-749.e7. Epub 2022 Jul 29 doi: 10.1016/j.jtct.2022.07.023. PMID: 35914728
Long-term clinical outcomes and predictive factors in patients with chronic ocular graft-versus-host disease.
Yoon HJ, Song GY, Yoon KC
Sci Rep 2022 Jul 29;12(1):12985. doi: 10.1038/s41598-022-17032-2. PMID: 35906359Free PMC Article

Clinical prediction guides

Delayed diagnosis of ocular graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Liao Y, Zhao W, Yang J, Li J, Chen J, Chen Z, Jin L, Li L, Huang F, Liang L
Ocul Surf 2024 Oct;34:1-8. Epub 2024 May 29 doi: 10.1016/j.jtos.2024.05.002. PMID: 38821405
Alteration of Meibum Lipidomics Profiling in Patients With Chronic Ocular Graft-Versus-Host Disease.
Zhao W, Yang J, Liao Y, Yang B, Lin S, Liu R, Liang L
Invest Ophthalmol Vis Sci 2023 Sep 1;64(12):35. doi: 10.1167/iovs.64.12.35. PMID: 37733365Free PMC Article
Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease.
Gehlsen U, Stern ME, Franklin J, Tahmaz V, Hallek M, Holtick U, Scheid C, Steven P
Transplant Cell Ther 2022 Nov;28(11):782.e1-782.e7. Epub 2022 Jul 31 doi: 10.1016/j.jtct.2022.07.027. PMID: 35921986
Biomarkers in Ocular Graft-Versus-Host Disease: Implications for the Involvement of B Cells.
Shen Z, Ma J, Peng R, Hu B, Zhao Y, Liu S, Hong J
Transplant Cell Ther 2022 Nov;28(11):749.e1-749.e7. Epub 2022 Jul 29 doi: 10.1016/j.jtct.2022.07.023. PMID: 35914728
Long-term clinical outcomes and predictive factors in patients with chronic ocular graft-versus-host disease.
Yoon HJ, Song GY, Yoon KC
Sci Rep 2022 Jul 29;12(1):12985. doi: 10.1038/s41598-022-17032-2. PMID: 35906359Free PMC Article

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