U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal HDL3b concentration

MedGen UID:
1688193
•Concept ID:
C5139338
•
Finding
HPO: HP:0032426

Definition

Any deviation from the normal concentration of the HDL3b subfraction in the blood circulation. An HDL3b particle is defined as an HDL particle with a size of 7.8-8.19 nm. [from HPO]

Recent clinical studies

Etiology

Shift of high-density lipoprotein size distribution toward large particles in patients with proteinuria.
Soto-Miranda E, Carreón-Torres E, Lorenzo K, Bazán-Salinas B, García-Sánchez C, Franco M, Posadas-Romero C, Fragoso JM, López-Olmos V, Madero M, Rodriguez-Pérez JM, Vargas-Alarcón G, Pérez-Méndez O
Clin Chim Acta 2012 Dec 24;414:241-5. Epub 2012 Oct 2 doi: 10.1016/j.cca.2012.09.028. PMID: 23041214
Characteristics of high-density lipoprotein subclasses distribution for subjects with desirable total cholesterol levels.
Tian L, Long S, Fu M, Liu Y, Xu Y, Jia L
Lipids Health Dis 2011 Apr 22;10:64. doi: 10.1186/1476-511X-10-64. PMID: 21513524Free PMC Article
High-density lipoprotein subclasses distribution and composition in Mexican adolescents with low HDL cholesterol and/or high triglyceride concentrations, and its association with insulin and C-reactive protein.
Medina-Urrutia A, Juarez-Rojas JG, Martínez-Alvarado R, Jorge-Galarza E, Posadas-Sánchez R, Cardoso-Saldaña G, Caracas-Portilla N, Mendoza-Perez E, Posadas-Romero C
Atherosclerosis 2008 Dec;201(2):392-7. Epub 2008 Mar 18 doi: 10.1016/j.atherosclerosis.2008.02.029. PMID: 18420210
Relationship between plasma lipid concentrations and HDL subclasses.
Yang Y, Yan B, Fu M, Xu Y, Tian Y
Clin Chim Acta 2005 Apr;354(1-2):49-58. Epub 2004 Dec 24 doi: 10.1016/j.cccn.2004.11.015. PMID: 15748599
Hyperinsulinemia and insulin resistance are associated with multiple abnormalities of lipoprotein subclasses in glucose-tolerant relatives of NIDDM patients. Botnia Study Group.
Tilly-Kiesi M, Knudsen P, Groop L, Taskinen MR
J Lipid Res 1996 Jul;37(7):1569-78. PMID: 8827527

Diagnosis

Hyperinsulinemia and insulin resistance are associated with multiple abnormalities of lipoprotein subclasses in glucose-tolerant relatives of NIDDM patients. Botnia Study Group.
Tilly-Kiesi M, Knudsen P, Groop L, Taskinen MR
J Lipid Res 1996 Jul;37(7):1569-78. PMID: 8827527

Prognosis

High-density lipoprotein subclass and particle size in coronary heart disease patients with or without diabetes.
Tian L, Long S, Li C, Liu Y, Chen Y, Zeng Z, Fu M
Lipids Health Dis 2012 May 15;11:54. doi: 10.1186/1476-511X-11-54. PMID: 22584085Free PMC Article

Clinical prediction guides

Shift of high-density lipoprotein size distribution toward large particles in patients with proteinuria.
Soto-Miranda E, Carreón-Torres E, Lorenzo K, Bazán-Salinas B, García-Sánchez C, Franco M, Posadas-Romero C, Fragoso JM, López-Olmos V, Madero M, Rodriguez-Pérez JM, Vargas-Alarcón G, Pérez-Méndez O
Clin Chim Acta 2012 Dec 24;414:241-5. Epub 2012 Oct 2 doi: 10.1016/j.cca.2012.09.028. PMID: 23041214
High-density lipoprotein subclass and particle size in coronary heart disease patients with or without diabetes.
Tian L, Long S, Li C, Liu Y, Chen Y, Zeng Z, Fu M
Lipids Health Dis 2012 May 15;11:54. doi: 10.1186/1476-511X-11-54. PMID: 22584085Free PMC Article
High-density lipoproteins are abnormal in young women with uncomplicated systemic lupus erythematosus.
Juárez-Rojas J, Medina-Urrutia A, Posadas-Sánchez R, Jorge-Galarza E, Mendoza-Pérez E, Caracas-Portilla N, Cardoso-Saldaña G, Muñoz-Gallegos G, Posadas-Romero C
Lupus 2008 Nov;17(11):981-7. doi: 10.1177/0961203308093072. PMID: 18852221
High-density lipoprotein subclasses distribution and composition in Mexican adolescents with low HDL cholesterol and/or high triglyceride concentrations, and its association with insulin and C-reactive protein.
Medina-Urrutia A, Juarez-Rojas JG, Martínez-Alvarado R, Jorge-Galarza E, Posadas-Sánchez R, Cardoso-Saldaña G, Caracas-Portilla N, Mendoza-Perez E, Posadas-Romero C
Atherosclerosis 2008 Dec;201(2):392-7. Epub 2008 Mar 18 doi: 10.1016/j.atherosclerosis.2008.02.029. PMID: 18420210
Hyperinsulinemia and insulin resistance are associated with multiple abnormalities of lipoprotein subclasses in glucose-tolerant relatives of NIDDM patients. Botnia Study Group.
Tilly-Kiesi M, Knudsen P, Groop L, Taskinen MR
J Lipid Res 1996 Jul;37(7):1569-78. PMID: 8827527

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...