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Refractory Cytomegalovirus Infection

MedGen UID:
1692165
Concept ID:
C5206792
Disease or Syndrome

Definition

A cytomegalovirus infection that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Cytomegalovirus Infection

Professional guidelines

PubMed

Ljungman P, de la Camara R, Robin C, Crocchiolo R, Einsele H, Hill JA, Hubacek P, Navarro D, Cordonnier C, Ward KN; 2017 European Conference on Infections in Leukaemia group
Lancet Infect Dis 2019 Aug;19(8):e260-e272. Epub 2019 May 29 doi: 10.1016/S1473-3099(19)30107-0. PMID: 31153807
Pierce B, Richardson CL, Lacloche L, Allen A, Ison MG
Transpl Infect Dis 2018 Apr;20(2):e12852. Epub 2018 Feb 22 doi: 10.1111/tid.12852. PMID: 29380479

Recent clinical studies

Etiology

Santos Bravo M, Plault N, Sánchez-Palomino S, Rodríguez C, Navarro Gabriel M, Mosquera MM, Fernández Avilés F, Suarez-Lledó M, Rovira M, Bodro M, Moreno A, Linares L, Cofan F, Berengua C, Esteva C, Cordero E, Martin-Davila P, Aranzamendi M, Pérez Jiménez AB, Vidal E, Fernández Sabé N, Len O, Hantz S, Alain S, Marcos MÁ; Spanish Network for Research in Infectious Diseases (REIPI) and the Group for the Study of Infection in Transplantation (GESITRA)
J Infect Dis 2022 Nov 1;226(9):1528-1536. doi: 10.1093/infdis/jiac349. PMID: 35993155
Karantoni E, Zavras PD, Su Y, Fang J, Tamari R, Cho C, Perales MA, Stern A, Papanicolaou GA
Transplant Cell Ther 2022 Jul;28(7):403.e1-403.e7. Epub 2022 Apr 25 doi: 10.1016/j.jtct.2022.04.016. PMID: 35476955Free PMC Article
Jinnouchi F, Mori Y, Yoshimoto G, Yamauchi T, Nunomura T, Yurino A, Hayashi M, Yuda J, Shima T, Odawara J, Takashima S, Kamezaki K, Kato K, Miyamoto T, Akashi K, Takenaka K
Int J Hematol 2022 Jan;115(1):96-106. Epub 2021 Oct 15 doi: 10.1007/s12185-021-03218-3. PMID: 34652633
Ljungman P, de la Camara R, Robin C, Crocchiolo R, Einsele H, Hill JA, Hubacek P, Navarro D, Cordonnier C, Ward KN; 2017 European Conference on Infections in Leukaemia group
Lancet Infect Dis 2019 Aug;19(8):e260-e272. Epub 2019 May 29 doi: 10.1016/S1473-3099(19)30107-0. PMID: 31153807
Chemaly RF, Chou S, Einsele H, Griffiths P, Avery R, Razonable RR, Mullane KM, Kotton C, Lundgren J, Komatsu TE, Lischka P, Josephson F, Douglas CM, Umeh O, Miller V, Ljungman P; Resistant Definitions Working Group of the Cytomegalovirus Drug Development Forum
Clin Infect Dis 2019 Apr 8;68(8):1420-1426. doi: 10.1093/cid/ciy696. PMID: 30137245Free PMC Article

Diagnosis

Del Rosal T, Quintana-Ortega C, Deyá-Martinez A, Soler-Palacín P, Goycochea-Valdivia WA, Salmón N, Pérez-Martínez A, Alsina L, Martín-Nalda A, Alonso L, Neth O, Bravo-Gallego LY, Gonzalez-Granado LI, Mendez-Echevarria A
Eur J Pediatr 2022 Nov;181(11):3889-3898. Epub 2022 Sep 14 doi: 10.1007/s00431-022-04614-5. PMID: 36102997Free PMC Article
Chou S, Wu J, Song K, Bo T
Antiviral Res 2019 Dec;172:104616. Epub 2019 Sep 27 doi: 10.1016/j.antiviral.2019.104616. PMID: 31568799Free PMC Article
Ljungman P, de la Camara R, Robin C, Crocchiolo R, Einsele H, Hill JA, Hubacek P, Navarro D, Cordonnier C, Ward KN; 2017 European Conference on Infections in Leukaemia group
Lancet Infect Dis 2019 Aug;19(8):e260-e272. Epub 2019 May 29 doi: 10.1016/S1473-3099(19)30107-0. PMID: 31153807
Takeda K, Sawada Y, Kumamoto T, Matsuyama R, Tanaka Y, Ohdan H, Endo I
Clin J Gastroenterol 2016 Feb;9(1):38-42. Epub 2016 Feb 18 doi: 10.1007/s12328-016-0627-x. PMID: 26892112

Therapy

Santos Bravo M, Plault N, Sánchez-Palomino S, Rodríguez C, Navarro Gabriel M, Mosquera MM, Fernández Avilés F, Suarez-Lledó M, Rovira M, Bodro M, Moreno A, Linares L, Cofan F, Berengua C, Esteva C, Cordero E, Martin-Davila P, Aranzamendi M, Pérez Jiménez AB, Vidal E, Fernández Sabé N, Len O, Hantz S, Alain S, Marcos MÁ; Spanish Network for Research in Infectious Diseases (REIPI) and the Group for the Study of Infection in Transplantation (GESITRA)
J Infect Dis 2022 Nov 1;226(9):1528-1536. doi: 10.1093/infdis/jiac349. PMID: 35993155
Karantoni E, Zavras PD, Su Y, Fang J, Tamari R, Cho C, Perales MA, Stern A, Papanicolaou GA
Transplant Cell Ther 2022 Jul;28(7):403.e1-403.e7. Epub 2022 Apr 25 doi: 10.1016/j.jtct.2022.04.016. PMID: 35476955Free PMC Article
Jinnouchi F, Mori Y, Yoshimoto G, Yamauchi T, Nunomura T, Yurino A, Hayashi M, Yuda J, Shima T, Odawara J, Takashima S, Kamezaki K, Kato K, Miyamoto T, Akashi K, Takenaka K
Int J Hematol 2022 Jan;115(1):96-106. Epub 2021 Oct 15 doi: 10.1007/s12185-021-03218-3. PMID: 34652633
Ljungman P, de la Camara R, Robin C, Crocchiolo R, Einsele H, Hill JA, Hubacek P, Navarro D, Cordonnier C, Ward KN; 2017 European Conference on Infections in Leukaemia group
Lancet Infect Dis 2019 Aug;19(8):e260-e272. Epub 2019 May 29 doi: 10.1016/S1473-3099(19)30107-0. PMID: 31153807
Wang E, Jan AS, Doan VP, Ferguson JB, Yeh JC
J Oncol Pharm Pract 2019 Oct;25(7):1731-1737. Epub 2018 Aug 31 doi: 10.1177/1078155218796188. PMID: 30170516

Prognosis

Tamzali Y, Pourcher V, Azoyan L, Ouali N, Barrou B, Conti F, Coutance G, Gay F, Tourret J, Boutolleau D
Transpl Int 2023;36:11295. Epub 2023 Jun 15 doi: 10.3389/ti.2023.11295. PMID: 37398559Free PMC Article
Del Rosal T, Quintana-Ortega C, Deyá-Martinez A, Soler-Palacín P, Goycochea-Valdivia WA, Salmón N, Pérez-Martínez A, Alsina L, Martín-Nalda A, Alonso L, Neth O, Bravo-Gallego LY, Gonzalez-Granado LI, Mendez-Echevarria A
Eur J Pediatr 2022 Nov;181(11):3889-3898. Epub 2022 Sep 14 doi: 10.1007/s00431-022-04614-5. PMID: 36102997Free PMC Article
Santos Bravo M, Plault N, Sánchez-Palomino S, Rodríguez C, Navarro Gabriel M, Mosquera MM, Fernández Avilés F, Suarez-Lledó M, Rovira M, Bodro M, Moreno A, Linares L, Cofan F, Berengua C, Esteva C, Cordero E, Martin-Davila P, Aranzamendi M, Pérez Jiménez AB, Vidal E, Fernández Sabé N, Len O, Hantz S, Alain S, Marcos MÁ; Spanish Network for Research in Infectious Diseases (REIPI) and the Group for the Study of Infection in Transplantation (GESITRA)
J Infect Dis 2022 Nov 1;226(9):1528-1536. doi: 10.1093/infdis/jiac349. PMID: 35993155
Karantoni E, Zavras PD, Su Y, Fang J, Tamari R, Cho C, Perales MA, Stern A, Papanicolaou GA
Transplant Cell Ther 2022 Jul;28(7):403.e1-403.e7. Epub 2022 Apr 25 doi: 10.1016/j.jtct.2022.04.016. PMID: 35476955Free PMC Article
Jinnouchi F, Mori Y, Yoshimoto G, Yamauchi T, Nunomura T, Yurino A, Hayashi M, Yuda J, Shima T, Odawara J, Takashima S, Kamezaki K, Kato K, Miyamoto T, Akashi K, Takenaka K
Int J Hematol 2022 Jan;115(1):96-106. Epub 2021 Oct 15 doi: 10.1007/s12185-021-03218-3. PMID: 34652633

Clinical prediction guides

Schultz BG, Kotton CN, Jutlla G, Ressa R, de Lacey T, Chowdhury E, Bo T, Fenu E, Gelone DK, Poirrier JE, Amorosi SL
J Med Virol 2024 Apr;96(4):e29609. doi: 10.1002/jmv.29609. PMID: 38647051
Tamzali Y, Pourcher V, Azoyan L, Ouali N, Barrou B, Conti F, Coutance G, Gay F, Tourret J, Boutolleau D
Transpl Int 2023;36:11295. Epub 2023 Jun 15 doi: 10.3389/ti.2023.11295. PMID: 37398559Free PMC Article
Santos Bravo M, Plault N, Sánchez-Palomino S, Rodríguez C, Navarro Gabriel M, Mosquera MM, Fernández Avilés F, Suarez-Lledó M, Rovira M, Bodro M, Moreno A, Linares L, Cofan F, Berengua C, Esteva C, Cordero E, Martin-Davila P, Aranzamendi M, Pérez Jiménez AB, Vidal E, Fernández Sabé N, Len O, Hantz S, Alain S, Marcos MÁ; Spanish Network for Research in Infectious Diseases (REIPI) and the Group for the Study of Infection in Transplantation (GESITRA)
J Infect Dis 2022 Nov 1;226(9):1528-1536. doi: 10.1093/infdis/jiac349. PMID: 35993155
Karantoni E, Zavras PD, Su Y, Fang J, Tamari R, Cho C, Perales MA, Stern A, Papanicolaou GA
Transplant Cell Ther 2022 Jul;28(7):403.e1-403.e7. Epub 2022 Apr 25 doi: 10.1016/j.jtct.2022.04.016. PMID: 35476955Free PMC Article
Jinnouchi F, Mori Y, Yoshimoto G, Yamauchi T, Nunomura T, Yurino A, Hayashi M, Yuda J, Shima T, Odawara J, Takashima S, Kamezaki K, Kato K, Miyamoto T, Akashi K, Takenaka K
Int J Hematol 2022 Jan;115(1):96-106. Epub 2021 Oct 15 doi: 10.1007/s12185-021-03218-3. PMID: 34652633

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