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Herpesvirus infection

MedGen UID:: 6823
•Concept ID:: C0019372
•: Disease or Syndrome

Synonyms:	Herpesviridae Infection; Herpesviridae Infections; Herpesvirus Infection; Herpesvirus Infections; Infection, Herpesviridae; Infection, Herpesvirus; Infections, Herpesviridae; Infections, Herpesvirus
SNOMED CT:	Herpesvirus infection (23513009); Herpes infection (23513009)

Definition

An infection caused by a herpesvirus. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVHerpesvirus infection

Pathological Conditions, Signs and Symptoms
- Clinical finding
  - Finding by Cause
    - Infection
      - viral disease
        DNA Virus Infections
        Herpesvirus infection
        Bovine Rhinotracheitis, Infectious
        Catarrhal Fever, Malignant
        Cytomegalovirus infection
        Acquired Cytomegaloviral Infection
        Congenital cytomegalovirus infection
        Current Cytomegalovirus Infection
        Cytomegaloviral gastritis
        Cytomegalovirus colitis
        Cytomegalovirus Gastroenteritis
        Cytomegalovirus pneumonia
        Cytomegalovirus retinitis
        Esophagitis caused by Cytomegalovirus
        Recurrent Cytomegalovirus Infection
        Refractory Cytomegalovirus Infection
        Epstein-Barr virus infection
        Burkitt lymphoma
        Adult Burkitt Lymphoma
        Atypical Burkitt/Burkitt-Like Lymphoma
        Breast Burkitt Lymphoma
        Burkitt Lymphoma by Ann Arbor Stage
        Burkitt Lymphoma with Plasmacytoid Differentiation
        Childhood Burkitt Lymphoma
        Classical Burkitt Lymphoma
        Colorectal Burkitt Lymphoma
        Cutaneous Burkitt Lymphoma
        EBV-Related Burkitt Lymphoma
        Gastric Burkitt Lymphoma
        Immunodeficiency-Related Burkitt Lymphoma
        Recurrent Burkitt Lymphoma
        Refractory Burkitt Lymphoma
        Small intestinal Burkitt lymphoma
        Splenic Burkitt Lymphoma
        Sporadic Burkitt Lymphoma
        Chronic Active EBV Disease
        Current EBV Infection
        Infectious mononucleosis
        Oral hairy leukoplakia
        Hairy Leukoplakia of Tongue
        Recurrent EBV Infection
        Severe Chronic Active EBV Infection
        Facial palsy
        Bilateral facial palsy
        Facial diplegia
        Congenital facial diplegia
        Unilateral facial palsy
        Herpes simplex encephalitis
        Herpes simplex infectious disease
        Genital herpes
        Herpes labialis
        Herpes simplex virus keratitis
        Herpes simplex dendritic keratitis
        Herpes stomatitis
        Herpetic vulvovaginitis
        Kaposi varicelliform eruption
        Neonatal Herpes Simplex Infection
        Human herpesvirus 8 infection
        Infection by human herpesvirus 6
        Kaposi sarcoma
        AIDS-Related Kaposi Sarcoma
        AIDS-Related Cervical Kaposi Sarcoma
        AIDS-Related Gastric Kaposi Sarcoma
        Cardiac Kaposi Sarcoma
        Central Nervous System Kaposi Sarcoma
        Conjunctival Kaposi Sarcoma
        Corneal Kaposi Sarcoma
        Digestive System Kaposi Sarcoma
        Anal Kaposi Sarcoma
        Appendix Kaposi Sarcoma
        Colorectal Kaposi sarcoma
        Esophageal Kaposi Sarcoma
        Extrahepatic Bile Duct Kaposi Sarcoma
        Gallbladder Kaposi Sarcoma
        Gastric Kaposi Sarcoma
        Liver Kaposi Sarcoma
        Small Intestinal Kaposi Sarcoma
        Endemic African Kaposi Sarcoma
        Iatrogenic Kaposi sarcoma
        Kaposi Sarcoma Related to Immunosuppressive Treatment
        Kaposi Sarcoma NCI Grade 2
        Kaposi Sarcoma NCI Grade 3
        Kaposi sarcoma, susceptibility to
        Lung Kaposi Sarcoma
        Lymphadenopathic Kaposi Sarcoma
        Metastatic Kaposi Sarcoma
        Advanced Kaposi Sarcoma
        Oral Cavity Kaposi Sarcoma
        Palate Kaposi Sarcoma
        Parotid Gland Kaposi Sarcoma
        Penile Kaposi Sarcoma
        Prostate Kaposi Sarcoma
        Recurrent Kaposi Sarcoma
        Refractory Kaposi Sarcoma
        Skin Kaposi Sarcoma
        Classic Kaposi sarcoma
        Vulvar Kaposi Sarcoma
        Marek Disease
        Pseudorabies
        Roseola Infantum
        Roseolovirus infectious disease
        Exanthema subitum
        Varicella zoster infection
        Chickenpox
        Congenital Varicella Zoster Infection
        Disseminated Oka Varicella Zoster Virus Infection
        Herpes zoster
        Geniculate herpes zoster
        Ophthalmic herpes zoster
        Zoster sine herpete
        Postvaricella encephalitis

Professional guidelines

PubMed

Exploration in the Mechanism of Ginsenoside Rg5 for the Treatment of Osteosarcoma by Network Pharmacology and Molecular Docking.

Liu MY, Jiang DX, Zhao X, Zhang L, Zhang Y, Liu ZD, Liu RZ, Li HJ, Rong XY, Gao YZ
Orthop Surg 2024 Feb;16(2):462-470. Epub 2023 Dec 12 doi: 10.1111/os.13971. PMID: 38086608 Free PMC Article

Prevention and Treatment of Cytomegalovirus Infections in Solid Organ Transplant Recipients.

Koval CE
Infect Dis Clin North Am 2018 Sep;32(3):581-597. doi: 10.1016/j.idc.2018.04.008. PMID: 30146024

Diagnosis and differential diagnosis of progressive lymphoproliferation and malignant lymphoma in persistent active herpesvirus infection.

Krueger GR, Ablashi DV, Salahuddin SZ, Josephs SF
J Virol Methods 1988 Sep;21(1-4):255-64. doi: 10.1016/0166-0934(88)90071-7. PMID: 2846616

See all (13)

Recent clinical studies

Etiology

PLCG2-associated immune dysregulation (PLAID) comprises broad and distinct clinical presentations related to functional classes of genetic variants.

Baysac K, Sun G, Nakano H, Schmitz EG, Cruz AC, Fisher C, Bailey AC; PLCG2-Immune Dysregulation Working Group, Mace E, Milner JD, Ombrello MJ
J Allergy Clin Immunol 2024 Jan;153(1):230-242. Epub 2023 Sep 26 doi: 10.1016/j.jaci.2023.08.036. PMID: 37769878 Free PMC Article

Association between human herpesvirus infection and cervical carcinoma: a systematic review and meta-analysis.

Zhang H, Cai S, Xia Y, Lin Y, Zhou G, Yu Y, Feng M
Virol J 2023 Dec 4;20(1):288. doi: 10.1186/s12985-023-02234-5. PMID: 38049836 Free PMC Article

Mendelian randomization reveals no correlations between herpesvirus infection and idiopathic pulmonary fibrosis.

Yan H, Zhu C, Jin X, Feng G
PLoS One 2023;18(11):e0295082. Epub 2023 Nov 28 doi: 10.1371/journal.pone.0295082. PMID: 38015883 Free PMC Article

Herpes simplex viruses (1 and 2) and varicella-zoster virus infections in an adult population with aseptic meningitis or encephalitis: A nine-year retrospective clinical study.

Lee GH, Kim J, Kim HW, Cho JW
Medicine (Baltimore) 2021 Nov 19;100(46):e27856. doi: 10.1097/MD.0000000000027856. PMID: 34797322 Free PMC Article

Herpesvirus infections and Alzheimer's disease: a Mendelian randomization study.

Huang SY, Yang YX, Kuo K, Li HQ, Shen XN, Chen SD, Cui M, Tan L, Dong Q, Yu JT
Alzheimers Res Ther 2021 Sep 24;13(1):158. doi: 10.1186/s13195-021-00905-5. PMID: 34560893 Free PMC Article

See all (154)

Diagnosis

Mendelian randomization reveals no correlations between herpesvirus infection and idiopathic pulmonary fibrosis.

Yan H, Zhu C, Jin X, Feng G
PLoS One 2023;18(11):e0295082. Epub 2023 Nov 28 doi: 10.1371/journal.pone.0295082. PMID: 38015883 Free PMC Article

Microglial mitophagy integrates the microbiota-gut-brain axis to restrain neuroinflammation during neurotropic herpesvirus infection.

Li F, Wang Y, Zheng K
Autophagy 2023 Feb;19(2):734-736. Epub 2022 Jul 23 doi: 10.1080/15548627.2022.2102309. PMID: 35849507 Free PMC Article

Herpes simplex viruses (1 and 2) and varicella-zoster virus infections in an adult population with aseptic meningitis or encephalitis: A nine-year retrospective clinical study.

Lee GH, Kim J, Kim HW, Cho JW
Medicine (Baltimore) 2021 Nov 19;100(46):e27856. doi: 10.1097/MD.0000000000027856. PMID: 34797322 Free PMC Article

Chronic lymphocytic leukemia and Richter transformation skin involvement recruited by herpesvirus infection.

Izquierdo FM, Suárez-Vilela D, de la Hera-Magallanes A, Honrado E
J Cutan Pathol 2021 May;48(5):713-716. Epub 2020 Nov 15 doi: 10.1111/cup.13906. PMID: 33098115

Genital herpesvirus infection.

Amstey MS
Clin Obstet Gynecol 1975 Mar;18(1):89-100. doi: 10.1097/00003081-197503000-00009. PMID: 164310

See all (163)

Therapy

Mendelian randomization reveals no correlations between herpesvirus infection and idiopathic pulmonary fibrosis.

Yan H, Zhu C, Jin X, Feng G
PLoS One 2023;18(11):e0295082. Epub 2023 Nov 28 doi: 10.1371/journal.pone.0295082. PMID: 38015883 Free PMC Article

Herpesvirus infections and Alzheimer's disease: a Mendelian randomization study.

Huang SY, Yang YX, Kuo K, Li HQ, Shen XN, Chen SD, Cui M, Tan L, Dong Q, Yu JT
Alzheimers Res Ther 2021 Sep 24;13(1):158. doi: 10.1186/s13195-021-00905-5. PMID: 34560893 Free PMC Article

Arginine inactivates human herpesvirus 2 and inhibits genital herpesvirus infection.

Ikeda K, Yamasaki H, Minami S, Suzuki Y, Tsujimoto K, Sekino Y, Irie H, Arakawa T, Koyama AH
Int J Mol Med 2012 Dec;30(6):1307-12. Epub 2012 Oct 4 doi: 10.3892/ijmm.2012.1149. PMID: 23042569

Herpesviruses and autoimmunity.

Posnett DN
Curr Opin Investig Drugs 2008 May;9(5):505-14. PMID: 18465661

Advances in the treatment of herpesvirus infection: the role of famciclovir.

Tyring SK
Clin Ther 1998 Jul-Aug;20(4):661-70. doi: 10.1016/s0149-2918(98)80129-x. PMID: 9737826

See all (113)

Prognosis

Mendelian randomization reveals no correlations between herpesvirus infection and idiopathic pulmonary fibrosis.

Yan H, Zhu C, Jin X, Feng G
PLoS One 2023;18(11):e0295082. Epub 2023 Nov 28 doi: 10.1371/journal.pone.0295082. PMID: 38015883 Free PMC Article

Herpes simplex viruses (1 and 2) and varicella-zoster virus infections in an adult population with aseptic meningitis or encephalitis: A nine-year retrospective clinical study.

Lee GH, Kim J, Kim HW, Cho JW
Medicine (Baltimore) 2021 Nov 19;100(46):e27856. doi: 10.1097/MD.0000000000027856. PMID: 34797322 Free PMC Article

Herpesvirus infections and Alzheimer's disease: a Mendelian randomization study.

Huang SY, Yang YX, Kuo K, Li HQ, Shen XN, Chen SD, Cui M, Tan L, Dong Q, Yu JT
Alzheimers Res Ther 2021 Sep 24;13(1):158. doi: 10.1186/s13195-021-00905-5. PMID: 34560893 Free PMC Article

Chronic lymphocytic leukemia and Richter transformation skin involvement recruited by herpesvirus infection.

Izquierdo FM, Suárez-Vilela D, de la Hera-Magallanes A, Honrado E
J Cutan Pathol 2021 May;48(5):713-716. Epub 2020 Nov 15 doi: 10.1111/cup.13906. PMID: 33098115

Advances in the treatment of herpesvirus infection: the role of famciclovir.

Tyring SK
Clin Ther 1998 Jul-Aug;20(4):661-70. doi: 10.1016/s0149-2918(98)80129-x. PMID: 9737826

See all (83)

Clinical prediction guides

Pseudorabies virus gM and its homologous proteins in herpesviruses induce mitochondria-related apoptosis involved in viral pathogenicity.

Zhou Q, Shi D, Tang YD, Zhang L, Hu B, Zheng C, Huang L, Weng C
PLoS Pathog 2024 Apr;20(4):e1012146. Epub 2024 Apr 26 doi: 10.1371/journal.ppat.1012146. PMID: 38669242 Free PMC Article

Interferon induced circRNAs escape herpesvirus host shutoff and suppress lytic infection.

Dremel SE, Tagawa T, Koparde VN, Hernandez-Perez C, Arbuckle JH, Kristie TM, Krug LT, Ziegelbauer JM
EMBO Rep 2024 Mar;25(3):1541-1569. Epub 2024 Jan 23 doi: 10.1038/s44319-023-00051-z. PMID: 38263330 Free PMC Article

PLCG2-associated immune dysregulation (PLAID) comprises broad and distinct clinical presentations related to functional classes of genetic variants.

Mendelian randomization reveals no correlations between herpesvirus infection and idiopathic pulmonary fibrosis.

Yan H, Zhu C, Jin X, Feng G
PLoS One 2023;18(11):e0295082. Epub 2023 Nov 28 doi: 10.1371/journal.pone.0295082. PMID: 38015883 Free PMC Article

Herpesvirus infections and Alzheimer's disease: a Mendelian randomization study.

Huang SY, Yang YX, Kuo K, Li HQ, Shen XN, Chen SD, Cui M, Tan L, Dong Q, Yu JT
Alzheimers Res Ther 2021 Sep 24;13(1):158. doi: 10.1186/s13195-021-00905-5. PMID: 34560893 Free PMC Article

See all (124)

Recent systematic reviews

Association between human herpesvirus infection and cervical carcinoma: a systematic review and meta-analysis.

Zhang H, Cai S, Xia Y, Lin Y, Zhou G, Yu Y, Feng M
Virol J 2023 Dec 4;20(1):288. doi: 10.1186/s12985-023-02234-5. PMID: 38049836 Free PMC Article

Study on the mechanism of Shujin Tongluo granules in treating cervical spondylosis based on network pharmacology and molecular docking.

Wang Y, Tao X, Gao Y, Jin Z, Guo S, Li Z, Wang M, Zhao R, Zhou W, Wu J
Medicine (Baltimore) 2023 Jul 21;102(29):e34030. doi: 10.1097/MD.0000000000034030. PMID: 37478234 Free PMC Article

See all (2)

MedGen

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Send to:

Herpesvirus infection

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

Recent activity