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Unresectable Breast Inflammatory Carcinoma

MedGen UID:
1702632
•Concept ID:
C5203935
•
Neoplastic Process
Synonym: Unresectable Inflammatory Breast Carcinoma

Definition

Inflammatory breast carcinoma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Breast Inflammatory Carcinoma

Professional guidelines

PubMed

Neoadjuvant nab-paclitaxel in the treatment of breast cancer.
Ueno NT, Mamounas EP
Breast Cancer Res Treat 2016 Apr;156(3):427-440. Epub 2016 Apr 12 doi: 10.1007/s10549-016-3778-z. PMID: 27072366Free PMC Article
DEGRO practical guidelines for radiotherapy of breast cancer V: Therapy for locally advanced and inflammatory breast cancer, as well as local therapy in cases with synchronous distant metastases.
Budach W, Matuschek C, Bölke E, Dunst J, Feyer P, Fietkau R, Haase W, Harms W, Piroth MD, Sautter-Bihl ML, Sedlmayer F, Souchon R, Wenz F, Sauer R; Breast Cancer Expert Panel of German Society of Radiation Oncology (DEGRO)
Strahlenther Onkol 2015 Aug;191(8):623-33. Epub 2015 May 12 doi: 10.1007/s00066-015-0843-1. PMID: 25963557Free PMC Article
High dose chemotherapy with autologous stem cell support for the treatment of metastatic breast cancer.
Ayash LJ
Cancer 1994 Jul 1;74(1 Suppl):532-5. doi: 10.1002/cncr.2820741343. PMID: 8004629

Recent clinical studies

Etiology

Histological findings of thyroid cancer after lenvatinib therapy.
Okubo Y, Toda S, Sato S, Yoshioka E, Ono K, Hasegawa C, Washimi K, Yokose T, Miyagi Y, Iwasaki H, Hayashi H
Histopathology 2023 Oct;83(4):657-663. Epub 2023 Jul 28 doi: 10.1111/his.15013. PMID: 37501641
Combination of Olaparib and Radiation Therapy for Triple Negative Breast Cancer: Preliminary Results of the RADIOPARP Phase 1 Trial.
Loap P, Loirat D, Berger F, Ricci F, Vincent-Salomon A, Ezzili C, Mosseri V, Fourquet A, Ezzalfani M, Kirova Y
Int J Radiat Oncol Biol Phys 2021 Feb 1;109(2):436-440. Epub 2020 Sep 21 doi: 10.1016/j.ijrobp.2020.09.032. PMID: 32971187
Radiation therapy for inflammatory breast cancer.
Orecchia R
Eur J Surg Oncol 2018 Aug;44(8):1148-1150. Epub 2018 May 17 doi: 10.1016/j.ejso.2018.05.015. PMID: 29853159
Anaplastic lymphoma kinase-directed therapy in inflammatory myofibroblastic tumors.
Tothova Z, Wagner AJ
Curr Opin Oncol 2012 Jul;24(4):409-13. doi: 10.1097/CCO.0b013e328354c155. PMID: 22664824
Paclitaxel in the multimodality treatment for inflammatory breast carcinoma.
Cristofanilli M, Buzdar AU, Sneige N, Smith T, Wasaff B, Ibrahim N, Booser D, Rivera E, Murray JL, Valero V, Ueno N, Singletary ES, Hunt K, Strom E, McNeese M, Stelling C, Hortobagyi GN
Cancer 2001 Oct 1;92(7):1775-82. doi: 10.1002/1097-0142(20011001)92:7<1775::aid-cncr1693>3.0.co;2-e. PMID: 11745249

Diagnosis

New Strategies for Locally Advanced Breast Cancer: A Review of Inflammatory Breast Cancer and Nonresponders.
Malhotra S, Tadros AB
Clin Breast Cancer 2024 Jun;24(4):301-309. Epub 2024 Jan 21 doi: 10.1016/j.clbc.2024.01.009. PMID: 38431513Free PMC Article
Inflammatory Breast Cancer: Is There a Role for Deescalation of Surgery?
Nakhlis F
Ann Surg Oncol 2022 Oct;29(10):6106-6113. Epub 2022 Jul 15 doi: 10.1245/s10434-022-12138-3. PMID: 35840847
Combination of Olaparib and Radiation Therapy for Triple Negative Breast Cancer: Preliminary Results of the RADIOPARP Phase 1 Trial.
Loap P, Loirat D, Berger F, Ricci F, Vincent-Salomon A, Ezzili C, Mosseri V, Fourquet A, Ezzalfani M, Kirova Y
Int J Radiat Oncol Biol Phys 2021 Feb 1;109(2):436-440. Epub 2020 Sep 21 doi: 10.1016/j.ijrobp.2020.09.032. PMID: 32971187
DEGRO practical guidelines for radiotherapy of breast cancer V: Therapy for locally advanced and inflammatory breast cancer, as well as local therapy in cases with synchronous distant metastases.
Budach W, Matuschek C, Bölke E, Dunst J, Feyer P, Fietkau R, Haase W, Harms W, Piroth MD, Sautter-Bihl ML, Sedlmayer F, Souchon R, Wenz F, Sauer R; Breast Cancer Expert Panel of German Society of Radiation Oncology (DEGRO)
Strahlenther Onkol 2015 Aug;191(8):623-33. Epub 2015 May 12 doi: 10.1007/s00066-015-0843-1. PMID: 25963557Free PMC Article
High-dose multimodality therapy with autologous stem-cell support for stage IIIB breast carcinoma.
Ayash LJ, Elias A, Ibrahim J, Schwartz G, Wheeler C, Reich E, Lynch C, Warren D, Shapiro C, Richardson P, Hurd D, Schnipper L, Frei E 3rd, Antman K
J Clin Oncol 1998 Mar;16(3):1000-7. doi: 10.1200/JCO.1998.16.3.1000. PMID: 9508183

Therapy

Histological findings of thyroid cancer after lenvatinib therapy.
Okubo Y, Toda S, Sato S, Yoshioka E, Ono K, Hasegawa C, Washimi K, Yokose T, Miyagi Y, Iwasaki H, Hayashi H
Histopathology 2023 Oct;83(4):657-663. Epub 2023 Jul 28 doi: 10.1111/his.15013. PMID: 37501641
Combination of Olaparib and Radiation Therapy for Triple Negative Breast Cancer: Preliminary Results of the RADIOPARP Phase 1 Trial.
Loap P, Loirat D, Berger F, Ricci F, Vincent-Salomon A, Ezzili C, Mosseri V, Fourquet A, Ezzalfani M, Kirova Y
Int J Radiat Oncol Biol Phys 2021 Feb 1;109(2):436-440. Epub 2020 Sep 21 doi: 10.1016/j.ijrobp.2020.09.032. PMID: 32971187
Updates in Neoadjuvant Therapy for Triple Negative Breast Cancer.
Tufano AM, Teplinsky E, Landry CA
Clin Breast Cancer 2021 Feb;21(1):1-9. Epub 2020 Jul 3 doi: 10.1016/j.clbc.2020.07.001. PMID: 32800492
Neoadjuvant nab-paclitaxel in the treatment of breast cancer.
Ueno NT, Mamounas EP
Breast Cancer Res Treat 2016 Apr;156(3):427-440. Epub 2016 Apr 12 doi: 10.1007/s10549-016-3778-z. PMID: 27072366Free PMC Article
Anaplastic lymphoma kinase-directed therapy in inflammatory myofibroblastic tumors.
Tothova Z, Wagner AJ
Curr Opin Oncol 2012 Jul;24(4):409-13. doi: 10.1097/CCO.0b013e328354c155. PMID: 22664824

Prognosis

Combination of Olaparib and Radiation Therapy for Triple Negative Breast Cancer: Preliminary Results of the RADIOPARP Phase 1 Trial.
Loap P, Loirat D, Berger F, Ricci F, Vincent-Salomon A, Ezzili C, Mosseri V, Fourquet A, Ezzalfani M, Kirova Y
Int J Radiat Oncol Biol Phys 2021 Feb 1;109(2):436-440. Epub 2020 Sep 21 doi: 10.1016/j.ijrobp.2020.09.032. PMID: 32971187
Updates in Neoadjuvant Therapy for Triple Negative Breast Cancer.
Tufano AM, Teplinsky E, Landry CA
Clin Breast Cancer 2021 Feb;21(1):1-9. Epub 2020 Jul 3 doi: 10.1016/j.clbc.2020.07.001. PMID: 32800492
Radiation therapy for inflammatory breast cancer.
Orecchia R
Eur J Surg Oncol 2018 Aug;44(8):1148-1150. Epub 2018 May 17 doi: 10.1016/j.ejso.2018.05.015. PMID: 29853159
Paclitaxel in the multimodality treatment for inflammatory breast carcinoma.
Cristofanilli M, Buzdar AU, Sneige N, Smith T, Wasaff B, Ibrahim N, Booser D, Rivera E, Murray JL, Valero V, Ueno N, Singletary ES, Hunt K, Strom E, McNeese M, Stelling C, Hortobagyi GN
Cancer 2001 Oct 1;92(7):1775-82. doi: 10.1002/1097-0142(20011001)92:7<1775::aid-cncr1693>3.0.co;2-e. PMID: 11745249
High-dose multimodality therapy with autologous stem-cell support for stage IIIB breast carcinoma.
Ayash LJ, Elias A, Ibrahim J, Schwartz G, Wheeler C, Reich E, Lynch C, Warren D, Shapiro C, Richardson P, Hurd D, Schnipper L, Frei E 3rd, Antman K
J Clin Oncol 1998 Mar;16(3):1000-7. doi: 10.1200/JCO.1998.16.3.1000. PMID: 9508183

Clinical prediction guides

Histological findings of thyroid cancer after lenvatinib therapy.
Okubo Y, Toda S, Sato S, Yoshioka E, Ono K, Hasegawa C, Washimi K, Yokose T, Miyagi Y, Iwasaki H, Hayashi H
Histopathology 2023 Oct;83(4):657-663. Epub 2023 Jul 28 doi: 10.1111/his.15013. PMID: 37501641
Impact of Anti-HER2 Treatments Combined With Atezolizumab on the Tumor Immune Microenvironment in Early or Metastatic Breast Cancer: Results From a Phase Ib Study.
Hamilton EP, Kaklamani V, Falkson C, Vidal GA, Ward PJ, Patre M, Chui SY, Rotmensch J, Gupta K, Molinero L, Li Y, Emens LA
Clin Breast Cancer 2021 Dec;21(6):539-551. Epub 2021 May 15 doi: 10.1016/j.clbc.2021.04.011. PMID: 34154926
Combination of Olaparib and Radiation Therapy for Triple Negative Breast Cancer: Preliminary Results of the RADIOPARP Phase 1 Trial.
Loap P, Loirat D, Berger F, Ricci F, Vincent-Salomon A, Ezzili C, Mosseri V, Fourquet A, Ezzalfani M, Kirova Y
Int J Radiat Oncol Biol Phys 2021 Feb 1;109(2):436-440. Epub 2020 Sep 21 doi: 10.1016/j.ijrobp.2020.09.032. PMID: 32971187
Updates in Neoadjuvant Therapy for Triple Negative Breast Cancer.
Tufano AM, Teplinsky E, Landry CA
Clin Breast Cancer 2021 Feb;21(1):1-9. Epub 2020 Jul 3 doi: 10.1016/j.clbc.2020.07.001. PMID: 32800492
Gemcitabine-related radiation recall in a patient with pancreatic cancer.
Saif MW, Sellers S, Russo S
Anticancer Drugs 2006 Jan;17(1):107-11. doi: 10.1097/01.cad.0000181590.85476.e3. PMID: 16317298

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