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Breast adenocarcinoma

MedGen UID:
167809
Concept ID:
C0858252
Neoplastic Process
Synonyms: Breast adenocarcinoma, somatic; Breast cancer, somatic
SNOMED CT: Adenocarcinoma of breast (865954003)
 
Monarch Initiative: MONDO:0004988

Definition

The most common histologic type of breast carcinoma. Representative examples include invasive ductal carcinoma not otherwise specified, ductal carcinoma in situ, inflammatory carcinoma, secretory carcinoma, signet ring cell carcinoma, tubular carcinoma, invasive lobular carcinoma, and lobular carcinoma in situ. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Gilligan M, Thakolwiboon S, Orozco E, Banks S, Flanagan EP, Lopez-Chiriboga S, Tillema JM, Mills JR, Pittock SJ, Valencia Sanchez C, Zekeridou A, Dubey D, McKeon A
Ann Clin Transl Neurol 2025 Jan;12(1):213-225. Epub 2024 Dec 21 doi: 10.1002/acn3.52273. PMID: 39708293Free PMC Article
Scarim CB, Chin CM
Anticancer Agents Med Chem 2022;22(12):2204-2240. doi: 10.2174/1871520621666211201152815. PMID: 34852749
He A, Alhariri JM, Sweren RJ, Kwatra MM, Kwatra SG
Biomed Res Int 2017;2017:4790810. Epub 2017 Sep 19 doi: 10.1155/2017/4790810. PMID: 29057261Free PMC Article

Recent clinical studies

Etiology

Aebi S, Karlsson P, Wapnir IL
Breast 2022 Mar;62 Suppl 1(Suppl 1):S58-S62. Epub 2021 Dec 15 doi: 10.1016/j.breast.2021.12.011. PMID: 34930650Free PMC Article
Poortmans PM, Weltens C, Fortpied C, Kirkove C, Peignaux-Casasnovas K, Budach V, van der Leij F, Vonk E, Weidner N, Rivera S, van Tienhoven G, Fourquet A, Noel G, Valli M, Guckenberger M, Koiter E, Racadot S, Abdah-Bortnyak R, Van Limbergen EF, Engelen A, De Brouwer P, Struikmans H, Bartelink H; European Organisation for Research and Treatment of Cancer Radiation Oncology and Breast Cancer Groups
Lancet Oncol 2020 Dec;21(12):1602-1610. Epub 2020 Nov 2 doi: 10.1016/S1470-2045(20)30472-1. PMID: 33152277
Johnston H, Dickinson P, Ivens A, Buck AH, Levine RD, Remacle F, Campbell CJ
Proc Natl Acad Sci U S A 2019 Sep 24;116(39):19753-19759. Epub 2019 Sep 10 doi: 10.1073/pnas.1909455116. PMID: 31506353Free PMC Article
Kurtz DM, Esfahani MS, Scherer F, Soo J, Jin MC, Liu CL, Newman AM, Dührsen U, Hüttmann A, Casasnovas O, Westin JR, Ritgen M, Böttcher S, Langerak AW, Roschewski M, Wilson WH, Gaidano G, Rossi D, Bahlo J, Hallek M, Tibshirani R, Diehn M, Alizadeh AA
Cell 2019 Jul 25;178(3):699-713.e19. Epub 2019 Jul 4 doi: 10.1016/j.cell.2019.06.011. PMID: 31280963Free PMC Article
Tadpetch K, Kaewmee B, Chantakaew K, Kantee K, Rukachaisirikul V, Phongpaichit S
Bioorg Med Chem Lett 2016 Aug 1;26(15):3612-6. Epub 2016 Jun 4 doi: 10.1016/j.bmcl.2016.06.007. PMID: 27311894

Diagnosis

Loch A, Teoh VWY, Hilmi IN
Tex Heart Inst J 2023 Dec 7;50(6) doi: 10.14503/THIJ-23-8230. PMID: 38087478Free PMC Article
Stagni V, Kaminari A, Sideratou Z, Sakellis E, Vlahopoulos SA, Tsiourvas D
Int J Pharm 2020 Jul 30;585:119465. Epub 2020 Jun 1 doi: 10.1016/j.ijpharm.2020.119465. PMID: 32497731
Huang RC, Chiu WJ, Po-Jung Lai I, Huang CC
Sci Rep 2015 May 14;5:10292. doi: 10.1038/srep10292. PMID: 25973571Free PMC Article
Bettegowda C, Sausen M, Leary RJ, Kinde I, Wang Y, Agrawal N, Bartlett BR, Wang H, Luber B, Alani RM, Antonarakis ES, Azad NS, Bardelli A, Brem H, Cameron JL, Lee CC, Fecher LA, Gallia GL, Gibbs P, Le D, Giuntoli RL, Goggins M, Hogarty MD, Holdhoff M, Hong SM, Jiao Y, Juhl HH, Kim JJ, Siravegna G, Laheru DA, Lauricella C, Lim M, Lipson EJ, Marie SK, Netto GJ, Oliner KS, Olivi A, Olsson L, Riggins GJ, Sartore-Bianchi A, Schmidt K, Shih lM, Oba-Shinjo SM, Siena S, Theodorescu D, Tie J, Harkins TT, Veronese S, Wang TL, Weingart JD, Wolfgang CL, Wood LD, Xing D, Hruban RH, Wu J, Allen PJ, Schmidt CM, Choti MA, Velculescu VE, Kinzler KW, Vogelstein B, Papadopoulos N, Diaz LA Jr
Sci Transl Med 2014 Feb 19;6(224):224ra24. doi: 10.1126/scitranslmed.3007094. PMID: 24553385Free PMC Article
Sakthivel KM, Prabhu VV, Guruvayoorappan C
Asian Pac J Cancer Prev 2012;13(5):1719-22. doi: 10.7314/apjcp.2012.13.5.1719. PMID: 22901110

Therapy

Loch A, Teoh VWY, Hilmi IN
Tex Heart Inst J 2023 Dec 7;50(6) doi: 10.14503/THIJ-23-8230. PMID: 38087478Free PMC Article
Ali LMA, Miyagawa K, Fukui N, Onofre M, El Cheikh K, Morère A, Clément S, Gary-Bobo M, Richeter S, Shinokubo H
Org Biomol Chem 2022 Nov 2;20(42):8217-8222. doi: 10.1039/d2ob01410f. PMID: 36043857
Aebi S, Karlsson P, Wapnir IL
Breast 2022 Mar;62 Suppl 1(Suppl 1):S58-S62. Epub 2021 Dec 15 doi: 10.1016/j.breast.2021.12.011. PMID: 34930650Free PMC Article
Poortmans PM, Weltens C, Fortpied C, Kirkove C, Peignaux-Casasnovas K, Budach V, van der Leij F, Vonk E, Weidner N, Rivera S, van Tienhoven G, Fourquet A, Noel G, Valli M, Guckenberger M, Koiter E, Racadot S, Abdah-Bortnyak R, Van Limbergen EF, Engelen A, De Brouwer P, Struikmans H, Bartelink H; European Organisation for Research and Treatment of Cancer Radiation Oncology and Breast Cancer Groups
Lancet Oncol 2020 Dec;21(12):1602-1610. Epub 2020 Nov 2 doi: 10.1016/S1470-2045(20)30472-1. PMID: 33152277
Kurtz DM, Esfahani MS, Scherer F, Soo J, Jin MC, Liu CL, Newman AM, Dührsen U, Hüttmann A, Casasnovas O, Westin JR, Ritgen M, Böttcher S, Langerak AW, Roschewski M, Wilson WH, Gaidano G, Rossi D, Bahlo J, Hallek M, Tibshirani R, Diehn M, Alizadeh AA
Cell 2019 Jul 25;178(3):699-713.e19. Epub 2019 Jul 4 doi: 10.1016/j.cell.2019.06.011. PMID: 31280963Free PMC Article

Prognosis

Farrag AM, Ibrahim MH, Mehany ABM, Ismail MMF
Bioorg Chem 2020 Dec;105:104378. Epub 2020 Oct 13 doi: 10.1016/j.bioorg.2020.104378. PMID: 33099167
Kurtz DM, Esfahani MS, Scherer F, Soo J, Jin MC, Liu CL, Newman AM, Dührsen U, Hüttmann A, Casasnovas O, Westin JR, Ritgen M, Böttcher S, Langerak AW, Roschewski M, Wilson WH, Gaidano G, Rossi D, Bahlo J, Hallek M, Tibshirani R, Diehn M, Alizadeh AA
Cell 2019 Jul 25;178(3):699-713.e19. Epub 2019 Jul 4 doi: 10.1016/j.cell.2019.06.011. PMID: 31280963Free PMC Article
Blay JY, Le Cesne A, Alberti L, Ray-Coquart I
Bull Cancer 2005 Feb;92(2):E13-8. PMID: 15749638
Sood S, Nair SB, Fenwick JD, Horgan K
J Laryngol Otol 1999 Nov;113(11):1036-8. doi: 10.1017/s0022215100145931. PMID: 10696391
Amin R
Br J Radiol 1999 Jun;72(858):610-2. doi: 10.1259/bjr.72.858.10560346. PMID: 10560346

Clinical prediction guides

Papanikolaou V, Kyrodimos E, Mastronikolis N, Tsiambas E, Ragos V, Chrysovergis A
J BUON 2021 May-Jun;26(3):769-773. PMID: 34268934
Savic D, Partridge EC, Newberry KM, Smith SB, Meadows SK, Roberts BS, Mackiewicz M, Mendenhall EM, Myers RM
Genome Res 2015 Oct;25(10):1581-9. Epub 2015 Sep 9 doi: 10.1101/gr.193540.115. PMID: 26355004Free PMC Article
Knight JC, Topping C, Mosley M, Kersemans V, Falzone N, Fernández-Varea JM, Cornelissen B
Eur J Nucl Med Mol Imaging 2015 Oct;42(11):1707-1717. Epub 2015 Jun 2 doi: 10.1007/s00259-015-3092-8. PMID: 26031435
Serebryanskaya TV, Lyakhov AS, Ivashkevich LS, Schur J, Frias C, Prokop A, Ott I
Dalton Trans 2015 Jan 21;44(3):1161-9. doi: 10.1039/c4dt03105a. PMID: 25413270
Blay JY, Le Cesne A, Alberti L, Ray-Coquart I
Bull Cancer 2005 Feb;92(2):E13-8. PMID: 15749638

Recent systematic reviews

Andrews AR, Kakadekar A, Schmidt RL, Murugan P, Greene DN
Arch Pathol Lab Med 2022 Jan 2;146(2):252-261. doi: 10.5858/arpa.2020-0704-RA. PMID: 33983412
Simapivapan P, Boltong A, Hodge A
Cancer Treat Rev 2016 Nov;50:155-167. Epub 2016 Sep 20 doi: 10.1016/j.ctrv.2016.09.010. PMID: 27693930

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