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Nasal Cavity Papilloma

MedGen UID:
1717787
•Concept ID:
C5236094
•
Neoplastic Process
Synonym: Nasal Cavity Schneiderian Papilloma

Definition

A papilloma that arises from the ciliated respiratory mucosa that lines the nasal cavity. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNasal Cavity Papilloma

Professional guidelines

PubMed

DIAGNOSIS AND TREATMENT OF PATIENTS WITH SINONASAL INVERTED PAPILLOMA.
Zabolotnyi D, Zabolotna D, Zinchenko D, Tsvirinko I, Kizim Y
Georgian Med News 2020 Sep;(306):31-37. PMID: 33130642
Clinical management of squamous cell carcinoma associated with sinonasal inverted papilloma.
Yasumatsu R, Nakashima T, Sato M, Nakano T, Kogo R, Hashimoto K, Sawatsubashi M, Nakagawa T
Auris Nasus Larynx 2017 Feb;44(1):98-103. Epub 2016 Jun 1 doi: 10.1016/j.anl.2016.04.004. PMID: 27108101
Endoscopic treatment of inverted papilloma: safety and efficacy.
Krouse JH
Am J Otolaryngol 2001 Mar-Apr;22(2):87-99. doi: 10.1053/ajot.2001.22563. PMID: 11283822

Recent clinical studies

Etiology

Inverted papilloma: The stubbornly persistent tumor of the sinonasal cavity.
Rotenberg BW
Am J Rhinol Allergy 2016 Mar-Apr;30(2):77-8. doi: 10.2500/ajra.2016.30.4309. PMID: 26980387Free PMC Article
Human papillomavirus-associated neoplasms of the sinonasal tract and nasopharynx.
Thavaraj S
Semin Diagn Pathol 2016 Mar;33(2):104-11. Epub 2015 Sep 9 doi: 10.1053/j.semdp.2015.09.011. PMID: 26482046
Results of endoscopic sinus surgery for the treatment of inverted papillomas.
Waitz G, Wigand ME
Laryngoscope 1992 Aug;102(8):917-22. doi: 10.1288/00005537-199208000-00012. PMID: 1495356
Inverted papilloma: evaluation with MR imaging.
Yousem DM, Fellows DW, Kennedy DW, Bolger WE, Kashima H, Zinreich SJ
Radiology 1992 Nov;185(2):501-5. doi: 10.1148/radiology.185.2.1410362. PMID: 1410362
Papillomatosis of nasal cavity and paranasal sinuses (inverted papilloma, squamous papilloma). A clinicopathologic study.
Snyder RN, Perzin KH
Cancer 1972 Sep;30(3):668-90. doi: 10.1002/1097-0142(197209)30:3<668::aid-cncr2820300315>3.0.co;2-b. PMID: 5075353

Diagnosis

Attachment-oriented endoscopic surgical management for inverted papillomas in the nasal cavity and paranasal sinuses.
Makihara S, Kariya S, Naito T, Uraguchi K, Matsumoto J, Noda Y, Okano M, Nishizaki K
Auris Nasus Larynx 2019 Oct;46(5):748-753. Epub 2019 Mar 2 doi: 10.1016/j.anl.2019.02.007. PMID: 30833129
Human papillomavirus-associated neoplasms of the sinonasal tract and nasopharynx.
Thavaraj S
Semin Diagn Pathol 2016 Mar;33(2):104-11. Epub 2015 Sep 9 doi: 10.1053/j.semdp.2015.09.011. PMID: 26482046
Pediatric otorhinolaryngic pathology: diagnosis of selected lesions.
Kapadia SB, Popek EJ, Barnes L
Pathol Annu 1994;29 Pt 1:159-209. PMID: 8127623
Inverted papilloma.
Brown JH, Chew FS
AJR Am J Roentgenol 1992 Aug;159(2):278. doi: 10.2214/ajr.159.2.1632339. PMID: 1632339
Inverted papilloma: evaluation with MR imaging.
Yousem DM, Fellows DW, Kennedy DW, Bolger WE, Kashima H, Zinreich SJ
Radiology 1992 Nov;185(2):501-5. doi: 10.1148/radiology.185.2.1410362. PMID: 1410362

Therapy

Intralesional cidofovir injections for the treatment of multifocal exophytic sinonasal papilloma.
Chatelet F, Vinciguerra A, Marc M, Herman P, Verillaud B
Int Forum Allergy Rhinol 2024 Nov;14(11):1834-1837. Epub 2024 Jun 27 doi: 10.1002/alr.23399. PMID: 38934682
Microwave ablation for the removal of pharyngeal benign lesions: A prospective pilot case series.
OuYang Z, Lou Z, Lou Z, Jin K, Sun J, Chen Z
Am J Otolaryngol 2021 May-Jun;42(3):102916. Epub 2021 Jan 13 doi: 10.1016/j.amjoto.2021.102916. PMID: 33485048
Intranasal endoscopic prelacrimal recess approach for maxillary sinus inverted papilloma.
Yu QQ, Guan G, Zhang NK, Zhang XW, Jiang Y, Lian YY, Liu TT, Jiang XD, Li N
Eur Arch Otorhinolaryngol 2018 Sep;275(9):2297-2302. Epub 2018 Aug 4 doi: 10.1007/s00405-018-5078-1. PMID: 30078130Free PMC Article
Small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses.
Babin E, Rouleau V, Vedrine PO, Toussaint B, de Raucourt D, Malard O, Cosmidis A, Makaeieff M, Dehesdin D
J Laryngol Otol 2006 Apr;120(4):289-97. Epub 2006 Mar 10 doi: 10.1017/S0022215106000594. PMID: 16526967
Management of inverted papilloma of the nasal cavity and paranasal sinuses: importance of radiation therapy.
Hug EB, Wang CC, Montgomery WW, Goodman ML
Int J Radiat Oncol Biol Phys 1993 Apr 30;26(1):67-72. doi: 10.1016/0360-3016(93)90174-t. PMID: 8482632

Prognosis

DEK-AFF2 Carcinoma of the Sinonasal Region and Skull Base: Detailed Clinicopathologic Characterization of a Distinctive Entity.
Rooper LM, Agaimy A, Dickson BC, Dueber JC, Eberhart CG, Gagan J, Hartmann A, Khararjian A, London NR, MacMillan CM, Palsgrove DN, Nix JS, Sandison A, Stoehr R, Truong T, Weinreb I, Bishop JA
Am J Surg Pathol 2021 Dec 1;45(12):1682-1693. doi: 10.1097/PAS.0000000000001741. PMID: 34049316
Human papillomavirus-associated neoplasms of the sinonasal tract and nasopharynx.
Thavaraj S
Semin Diagn Pathol 2016 Mar;33(2):104-11. Epub 2015 Sep 9 doi: 10.1053/j.semdp.2015.09.011. PMID: 26482046
Results of endoscopic sinus surgery for the treatment of inverted papillomas.
Waitz G, Wigand ME
Laryngoscope 1992 Aug;102(8):917-22. doi: 10.1288/00005537-199208000-00012. PMID: 1495356
Carcinoma of the nasal cavity and paranasal sinuses: incidence and presentation of different histological types.
Robin PE, Powell DJ, Stansbie JM
Clin Otolaryngol Allied Sci 1979 Dec;4(6):431-56. doi: 10.1111/j.1365-2273.1979.tb01776.x. PMID: 393432
Papillomatosis of nasal cavity and paranasal sinuses (inverted papilloma, squamous papilloma). A clinicopathologic study.
Snyder RN, Perzin KH
Cancer 1972 Sep;30(3):668-90. doi: 10.1002/1097-0142(197209)30:3<668::aid-cncr2820300315>3.0.co;2-b. PMID: 5075353

Clinical prediction guides

Attachment-oriented endoscopic surgical management for inverted papillomas in the nasal cavity and paranasal sinuses.
Makihara S, Kariya S, Naito T, Uraguchi K, Matsumoto J, Noda Y, Okano M, Nishizaki K
Auris Nasus Larynx 2019 Oct;46(5):748-753. Epub 2019 Mar 2 doi: 10.1016/j.anl.2019.02.007. PMID: 30833129
p53 mutations in oral cavity carcinoma.
Ragos V, S Mastronikolis N, Tsiambas E, Baliou E, N Mastronikolis S, Tsoukalas N, E Patsouri E, P Fotiades P
J BUON 2018 Nov-Dec;23(6):1569-1572. PMID: 30610778
Intranasal endoscopic prelacrimal recess approach for maxillary sinus inverted papilloma.
Yu QQ, Guan G, Zhang NK, Zhang XW, Jiang Y, Lian YY, Liu TT, Jiang XD, Li N
Eur Arch Otorhinolaryngol 2018 Sep;275(9):2297-2302. Epub 2018 Aug 4 doi: 10.1007/s00405-018-5078-1. PMID: 30078130Free PMC Article
Human papillomavirus-associated neoplasms of the sinonasal tract and nasopharynx.
Thavaraj S
Semin Diagn Pathol 2016 Mar;33(2):104-11. Epub 2015 Sep 9 doi: 10.1053/j.semdp.2015.09.011. PMID: 26482046
The role of radiation therapy in inverted papilloma of the nasal cavity and paranasal sinuses.
Guedea F, Mendenhall WM, Parsons JT, Million RR
Int J Radiat Oncol Biol Phys 1991 Apr;20(4):777-80. doi: 10.1016/0360-3016(91)90022-v. PMID: 2004954

Recent systematic reviews

A Systematic Review of Definitive Treatment for Inverted Papilloma Attachment Site and Associations With Recurrence.
Trent MS, Goshtasbi K, Hui L, Stuyt JAG, Adappa ND, Palmer JN, Kuan EC
Otolaryngol Head Neck Surg 2022 Sep;167(3):425-433. Epub 2021 Oct 12 doi: 10.1177/01945998211051975. PMID: 34637363
Survival Outcomes of De Novo vs Inverted Papilloma-Associated Sinonasal Squamous Cell Carcinoma: A Systematic Review and Meta-analysis.
Lee JJ, Peterson AM, Embry TW, Wamkpah NS, Kallogjeri D, Doering MM, Schneider JS, Klatt-Cromwell CN, Pipkorn P
JAMA Otolaryngol Head Neck Surg 2021 Apr 1;147(4):350-359. doi: 10.1001/jamaoto.2020.5261. PMID: 33507208Free PMC Article
Malignant transformation of sinonasal inverted papilloma and related genetic alterations: a systematic review.
Re M, Gioacchini FM, Bajraktari A, Tomasetti M, Kaleci S, Rubini C, Bertini A, Magliulo G, Pasquini E
Eur Arch Otorhinolaryngol 2017 Aug;274(8):2991-3000. Epub 2017 Apr 21 doi: 10.1007/s00405-017-4571-2. PMID: 28432463
Inverted papilloma of the sphenoid sinus: clinical presentation, management, and systematic review of the literature.
Guillemaud JP, Witterick IJ
Laryngoscope 2009 Dec;119(12):2466-71. doi: 10.1002/lary.20718. PMID: 19798734
Endoscopic treatment of inverted papilloma: safety and efficacy.
Krouse JH
Am J Otolaryngol 2001 Mar-Apr;22(2):87-99. doi: 10.1053/ajot.2001.22563. PMID: 11283822

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