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Benign neoplasm of nasal cavity

MedGen UID:
83859
•Concept ID:
C0347215
•
Neoplastic Process
Synonyms: Benign Nasal Cavity Neoplasm; benign nasal cavity neoplasm; Benign Nasal Cavity Tumor; benign nasal cavity tumor; benign nasal cavity tumour; Benign Neoplasm of Nasal Cavity; benign neoplasm of nasal cavity; Benign Neoplasm of the Nasal Cavity; benign neoplasm of the nasal cavity; Benign tumor of nasal cavity; Benign Tumor of Nasal Cavity; benign tumor of nasal cavity; Benign Tumor of the Nasal Cavity; benign tumor of the nasal cavity; benign tumour of nasal cavity; benign tumour of the nasal cavity; nasal cavity benign neoplasm
SNOMED CT: Benign tumor of nasal cavity (92241005); Benign neoplasm of nasal cavity (92241005)
 
Monarch Initiative: MONDO:0021475

Definition

A neoplasm that arises from the nasal cavity and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include Schneiderian papilloma and salivary gland-type adenoma. [from NCI]

Professional guidelines

PubMed

Expert Consensus Statement: Management of Dysphagia in Head and Neck Cancer Patients.
Kuhn MA, Gillespie MB, Ishman SL, Ishii LE, Brody R, Cohen E, Dhar SI, Hutcheson K, Jefferson G, Johnson F, Rameau A, Sher D, Starmer H, Strohl M, Ulmer K, Vaitaitis V, Begum S, Batjargal M, Dhepyasuwan N
Otolaryngol Head Neck Surg 2023 Apr;168(4):571-592. doi: 10.1002/ohn.302. PMID: 36965195
The contemporary management of cancers of the sinonasal tract in adults.
Thawani R, Kim MS, Arastu A, Feng Z, West MT, Taflin NF, Thein KZ, Li R, Geltzeiler M, Lee N, Fuller CD, Grandis JR, Floudas CS, Heinrich MC, Hanna E, Chandra RA
CA Cancer J Clin 2023 Jan;73(1):72-112. Epub 2022 Aug 2 doi: 10.3322/caac.21752. PMID: 35916666Free PMC Article
Selection of lymph node target volumes for definitive head and neck radiation therapy: a 2019 Update.
Biau J, Lapeyre M, Troussier I, Budach W, Giralt J, Grau C, Kazmierska J, Langendijk JA, Ozsahin M, O'Sullivan B, Bourhis J, Grégoire V
Radiother Oncol 2019 May;134:1-9. Epub 2019 Jan 30 doi: 10.1016/j.radonc.2019.01.018. PMID: 31005201

Recent clinical studies

Etiology

Update on olfactory neuroblastoma.
Lopez F, Agaimy A, Franchi A, Suárez C, Vander Poorten V, Mäkitie AA, Homma A, Eisbruch A, Olsen KD, Saba NF, Nuyts S, Snyderman C, Beitler JJ, Corry J, Hanna E, Hellquist H, Rinaldo A, Ferlito A
Virchows Arch 2024 Apr;484(4):567-585. Epub 2024 Feb 22 doi: 10.1007/s00428-024-03758-z. PMID: 38386106
Inverted papilloma: The stubbornly persistent tumor of the sinonasal cavity.
Rotenberg BW
Am J Rhinol Allergy 2016 Mar-Apr;30(2):77-8. doi: 10.2500/ajra.2016.30.4309. PMID: 26980387Free PMC Article
Introduction.
Bishop JA
Semin Diagn Pathol 2016 Mar;33(2):61. Epub 2015 Dec 29 doi: 10.1053/j.semdp.2015.12.002. PMID: 26754864
Malignant melanoma of the nasal cavity treated with stereotactic radiotherapy using CyberKnife: report of 2 cases.
Abe T, Ebara T, Miyaura K, Kumazaki Y, Nakahira M, Sugasawa M, Shikama N, Kato S
Am J Otolaryngol 2015 Mar-Apr;36(2):306-9. Epub 2014 Dec 2 doi: 10.1016/j.amjoto.2014.11.010. PMID: 25510209
Ethmoidal myofibroblastoma.
Samuel D, Thomas DM, Tierney PA, Levine T, Patel KS
J Otolaryngol 1995 Oct;24(5):313-6. PMID: 8537994

Diagnosis

Intraosseous Hemangioma of the Ethmoid Sinus.
Caceres C, Kreicher KL, Wu Q, Falcone TE
Ear Nose Throat J 2023 Jul;102(7):425-427. Epub 2021 Apr 29 doi: 10.1177/01455613211014321. PMID: 33915054
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Nasal Cavity, Paranasal Sinuses and Skull Base.
Thompson LDR, Bishop JA
Head Neck Pathol 2022 Mar;16(1):1-18. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01406-5. PMID: 35312976Free PMC Article
Esthesioneuroblastoma: A Comprehensive Review of Diagnosis, Management, and Current Treatment Options.
Fiani B, Quadri SA, Cathel A, Farooqui M, Ramachandran A, Siddiqi I, Ghanchi H, Zafar A, Berman BW, Siddiqi J
World Neurosurg 2019 Jun;126:194-211. Epub 2019 Mar 9 doi: 10.1016/j.wneu.2019.03.014. PMID: 30862589
Esthesioneuroblastoma.
Girod D, Hanna E, Marentette L
Head Neck 2001 Jun;23(6):500-5. doi: 10.1002/hed.1067. PMID: 11360314
OLFACTORY NEUROBLASTOMA.
GRAHNE B
Acta Otolaryngol 1965 Jan;59:55-64. doi: 10.3109/00016486509128546. PMID: 14289923

Therapy

A Rapidly Progressing Polycystic Liver Disease?
Dong ZR, Zhi XT, Li T
Gastroenterology 2020 Jan;158(1):e9-e11. Epub 2019 Jul 31 doi: 10.1053/j.gastro.2019.07.046. PMID: 31376387
Pediatric pituitary adenomas.
Walz PC, Drapeau A, Shaikhouni A, Eide J, Rugino AJ, Mohyeldin A, Carrau R, Prevedello D
Childs Nerv Syst 2019 Nov;35(11):2107-2118. Epub 2019 Jul 13 doi: 10.1007/s00381-019-04293-y. PMID: 31302729
Esthesioneuroblastoma: A Comprehensive Review of Diagnosis, Management, and Current Treatment Options.
Fiani B, Quadri SA, Cathel A, Farooqui M, Ramachandran A, Siddiqi I, Ghanchi H, Zafar A, Berman BW, Siddiqi J
World Neurosurg 2019 Jun;126:194-211. Epub 2019 Mar 9 doi: 10.1016/j.wneu.2019.03.014. PMID: 30862589
New Onset of Blurred Vision and Floaters.
Zhu AY, Channa R
JAMA Ophthalmol 2019 Feb 1;137(2):224-225. doi: 10.1001/jamaophthalmol.2018.4511. PMID: 30520974
Nasopharyngeal carcinoma.
Brennan B
Orphanet J Rare Dis 2006 Jun 26;1:23. doi: 10.1186/1750-1172-1-23. PMID: 16800883Free PMC Article

Prognosis

Olfactory Neuroblastoma.
Veyrat M, Vérillaud B, Fiaux-Camous D, Froelich S, Bresson D, Nicolai P, Herman P
Adv Otorhinolaryngol 2020;84:154-167. Epub 2020 Jul 30 doi: 10.1159/000457935. PMID: 32731231
Introduction.
Bishop JA
Semin Diagn Pathol 2016 Mar;33(2):61. Epub 2015 Dec 29 doi: 10.1053/j.semdp.2015.12.002. PMID: 26754864
Hematolymphoid lesions of the sinonasal tract.
Crane GM, Duffield AS
Semin Diagn Pathol 2016 Mar;33(2):71-80. Epub 2015 Sep 9 doi: 10.1053/j.semdp.2015.09.008. PMID: 26472692Free PMC Article
Malignant melanoma of the nasal cavity treated with stereotactic radiotherapy using CyberKnife: report of 2 cases.
Abe T, Ebara T, Miyaura K, Kumazaki Y, Nakahira M, Sugasawa M, Shikama N, Kato S
Am J Otolaryngol 2015 Mar-Apr;36(2):306-9. Epub 2014 Dec 2 doi: 10.1016/j.amjoto.2014.11.010. PMID: 25510209
Ethmoidal myofibroblastoma.
Samuel D, Thomas DM, Tierney PA, Levine T, Patel KS
J Otolaryngol 1995 Oct;24(5):313-6. PMID: 8537994

Clinical prediction guides

Role of induction chemotherapy in advanced-stage olfactory neuroblastoma.
Cho SW, Keam B, Lee KW, Kim JW, Han DH, Kim HJ, Kim JW, Kim DY, Rhee CS, Bae YJ, Kim JH, Eom KY, Wu HG, Kim YH, Kim CY, Paek SH, Kim H, Won TB
Int Forum Allergy Rhinol 2024 Dec;14(12):1882-1891. Epub 2024 Aug 20 doi: 10.1002/alr.23428. PMID: 39162101
Update on olfactory neuroblastoma.
Lopez F, Agaimy A, Franchi A, Suárez C, Vander Poorten V, Mäkitie AA, Homma A, Eisbruch A, Olsen KD, Saba NF, Nuyts S, Snyderman C, Beitler JJ, Corry J, Hanna E, Hellquist H, Rinaldo A, Ferlito A
Virchows Arch 2024 Apr;484(4):567-585. Epub 2024 Feb 22 doi: 10.1007/s00428-024-03758-z. PMID: 38386106
Intraosseous Hemangioma of the Ethmoid Sinus.
Caceres C, Kreicher KL, Wu Q, Falcone TE
Ear Nose Throat J 2023 Jul;102(7):425-427. Epub 2021 Apr 29 doi: 10.1177/01455613211014321. PMID: 33915054
Endoscopic management of Esthesioneuroblastoma: Our experience and review of the literature.
Klironomos G, Gonen L, Au K, Monteiro E, Mansouri A, Turel MK, Witterick I, Vescan A, Zadeh G, Gentili F
J Clin Neurosci 2018 Dec;58:117-123. Epub 2018 Oct 16 doi: 10.1016/j.jocn.2018.09.011. PMID: 30340976
Of mice and men: olfactory neuroblastoma among animals and humans.
Lubojemska A, Borejko M, Czapiewski P, Dziadziuszko R, Biernat W
Vet Comp Oncol 2016 Sep;14(3):e70-82. Epub 2014 Jul 12 doi: 10.1111/vco.12102. PMID: 25041470

Recent systematic reviews

Nasal Cavity and Paranasal Sinus Cancer: Diagnosis and Treatment.
Jakimovska F, Stojkovski I, Kjosevska E
Curr Oncol Rep 2024 Sep;26(9):1057-1069. Epub 2024 Jun 27 doi: 10.1007/s11912-024-01566-x. PMID: 38935225
Diagnosis, Treatment and Follow-Up of Sinonasal Leiomyomas: A Systematic Review.
Runge A, Randhawa A, Mayo-Patiño M, Santer M, Hartl R, Dejaco D, Eloy JA
Am J Rhinol Allergy 2023 Sep;37(5):586-592. Epub 2023 Apr 24 doi: 10.1177/19458924231170464. PMID: 37093753
Expert Consensus Statement: Management of Dysphagia in Head and Neck Cancer Patients.
Kuhn MA, Gillespie MB, Ishman SL, Ishii LE, Brody R, Cohen E, Dhar SI, Hutcheson K, Jefferson G, Johnson F, Rameau A, Sher D, Starmer H, Strohl M, Ulmer K, Vaitaitis V, Begum S, Batjargal M, Dhepyasuwan N
Otolaryngol Head Neck Surg 2023 Apr;168(4):571-592. doi: 10.1002/ohn.302. PMID: 36965195
Sino-nasal hemangiopericytoma: a case series and systematic literature review.
Warman M, Syn-Hershko A, Cohen O, Tzipin Y, Lahav Y, Tessler I
Eur Arch Otorhinolaryngol 2022 Aug;279(8):3989-3996. Epub 2022 Feb 1 doi: 10.1007/s00405-021-07239-w. PMID: 35103868
Characteristics and management of sinonasal paragangliomas: a systematic review.
Nguyen BK, Patel NM, Arianpour K, Svider PF, Folbe AJ, Hsueh WD, Eloy JA
Int Forum Allergy Rhinol 2019 Apr;9(4):413-426. Epub 2018 Dec 20 doi: 10.1002/alr.22261. PMID: 30570216

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