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Beta-Catenin-Activated Inflammatory Hepatocellular Adenoma

MedGen UID:
1727443
•Concept ID:
C5417717
•
Neoplastic Process

Definition

Hepatocellular adenoma with features of both beta-catenin-activated hepatocellular adenoma and inflammatory hepatocellular adenoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBeta-Catenin-Activated Inflammatory Hepatocellular Adenoma

Professional guidelines

PubMed

Hepatocellular adenomas in the Turkish population: reclassification according to updated World Health Organization criteria.
Deniz K, Umetsu SE, Ferrell L, Yılmaz F, Güllüoğlu M, Sağol Ö, Doğusoy GB, Kırımlıoğlu H, Turhan N, Doran F, Kepil N, Çelikel ÇA, Nart D, Özgüven BY, Ceyran B, Karadağ N, Kır G, Erden E, Yılmaz G, Akyol G
Histopathology 2021 Jul;79(1):23-33. Epub 2021 Apr 12 doi: 10.1111/his.14330. PMID: 33406290
Subclassification of hepatocellular adenomas: practical considerations in the implementation of the Bordeaux criteria.
Miller GC, Campbell CM, Manoharan B, Bryant R, Cavallucci D, O'Rourke N, Clouston AD
Pathology 2018 Oct;50(6):593-599. Epub 2018 Aug 24 doi: 10.1016/j.pathol.2018.05.003. PMID: 30149989
Management of Hepatocellular Adenoma: Recent Advances.
Agrawal S, Agarwal S, Arnason T, Saini S, Belghiti J
Clin Gastroenterol Hepatol 2015 Jul;13(7):1221-30. Epub 2014 Jun 5 doi: 10.1016/j.cgh.2014.05.023. PMID: 24909909

Recent clinical studies

Diagnosis

Malignant transformation of a β-catenin inflammatory adenoma due to an S45 β-catenin-activating mutation present 12 years before.
Sempoux C, Bisig B, Couchy G, Balabaud C, Zucman-Rossi J, Bioulac-Sage P
Hum Pathol 2017 Apr;62:122-125. Epub 2016 Oct 28 doi: 10.1016/j.humpath.2016.10.004. PMID: 27984126

Prognosis

Malignant transformation of a β-catenin inflammatory adenoma due to an S45 β-catenin-activating mutation present 12 years before.
Sempoux C, Bisig B, Couchy G, Balabaud C, Zucman-Rossi J, Bioulac-Sage P
Hum Pathol 2017 Apr;62:122-125. Epub 2016 Oct 28 doi: 10.1016/j.humpath.2016.10.004. PMID: 27984126

Supplemental Content

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    Practice guidelines

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