U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Adenoma

MedGen UID:
125
Concept ID:
C0001430
Neoplastic Process
Synonym: Adenomas
SNOMED CT: Benign adenomatous neoplasm (443416007); Benign adenomatous neoplasm (1187227004); Adenoma (1187375007); Adenoma (1187379001); Benign adenoma (1187379001)
 
Monarch Initiative: MONDO:0004972

Definition

A neoplasm arising from the epithelium. It may be encapsulated or non-encapsulated but non-invasive. The neoplastic epithelial cells may or may not display cellular atypia or dysplasia. In the gastrointestinal tract, when dysplasia becomes severe it is sometimes called carcinoma in situ. Representative examples are pituitary gland adenoma, follicular adenoma of the thyroid gland, and adenomas (or adenomatous polyps) of the gastrointestinal tract. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdenoma

Professional guidelines

PubMed

Giustina A, Biermasz N, Casanueva FF, Fleseriu M, Mortini P, Strasburger C, van der Lely AJ, Wass J, Melmed S; Acromegaly Consensus Group
Pituitary 2024 Feb;27(1):7-22. Epub 2023 Nov 3 doi: 10.1007/s11102-023-01360-1. PMID: 37923946Free PMC Article
Fassnacht M, Tsagarakis S, Terzolo M, Tabarin A, Sahdev A, Newell-Price J, Pelsma I, Marina L, Lorenz K, Bancos I, Arlt W, Dekkers OM
Eur J Endocrinol 2023 Jul 20;189(1):G1-G42. doi: 10.1093/ejendo/lvad066. PMID: 37318239
Reincke M, Bancos I, Mulatero P, Scholl UI, Stowasser M, Williams TA
Lancet Diabetes Endocrinol 2021 Dec;9(12):876-892. doi: 10.1016/S2213-8587(21)00210-2. PMID: 34798068

Recent clinical studies

Etiology

Myers L, Ahn J
Clin Liver Dis 2020 Aug;24(3):389-403. Epub 2020 Jun 3 doi: 10.1016/j.cld.2020.04.013. PMID: 32620279
Sundling RA, So E, Logan DB
Foot Ankle Spec 2017 Apr;10(2):167-169. Epub 2016 Sep 20 doi: 10.1177/1938640016666927. PMID: 27587378
Sav A, Rotondo F, Syro LV, Di Ieva A, Cusimano MD, Kovacs K
Endocrinol Metab Clin North Am 2015 Mar;44(1):99-104. Epub 2014 Nov 4 doi: 10.1016/j.ecl.2014.10.008. PMID: 25732646
Wasylik K, Kim JC, Amedee RG
J La State Med Soc 2001 Jan;153(1):12-6. PMID: 11272444
Tallini G
Virchows Arch 1998 Jul;433(1):5-12. doi: 10.1007/s004280050209. PMID: 9692819

Diagnosis

Almajnooni A, Vega M, Cheng L, Gattuso P, Allen-Proctor MK
Diagn Cytopathol 2023 Apr;51(4):E137-E141. Epub 2023 Jan 23 doi: 10.1002/dc.25103. PMID: 36688374
McCarthy M, Whaley RD, Erickson LA
Mayo Clin Proc 2022 Nov;97(11):2168-2169. doi: 10.1016/j.mayocp.2022.09.015. PMID: 36333022
Brownlee BP, Mann D, Glenn C, McKinney KA
Otolaryngol Clin North Am 2022 Apr;55(2):343-350. doi: 10.1016/j.otc.2021.12.015. PMID: 35365312
Fleseriu M, Popovic V
Rev Endocr Metab Disord 2020 Jun;21(2):201-202. doi: 10.1007/s11154-020-09561-w. PMID: 32488740
Cerdà Gabaroi D, Corominas Macías H, Reina Sanz D, Fíguls Poch R
Reumatol Clin 2013 Mar-Apr;9(2):128-9. Epub 2012 Apr 7 doi: 10.1016/j.reuma.2012.01.004. PMID: 22484062

Therapy

Xu H, Tang RSY, Lam TYT, Zhao G, Lau JYW, Liu Y, Wu Q, Rong L, Xu W, Li X, Wong SH, Cai S, Wang J, Liu G, Ma T, Liang X, Mak JWY, Xu H, Yuan P, Cao T, Li F, Ye Z, Shutian Z, Sung JJY
Clin Gastroenterol Hepatol 2023 Feb;21(2):337-346.e3. Epub 2022 Jul 19 doi: 10.1016/j.cgh.2022.07.006. PMID: 35863686
Yin J, Ngiam KY, Teo HH
J Med Internet Res 2021 Apr 22;23(4):e25759. doi: 10.2196/25759. PMID: 33885365Free PMC Article
Tołoczko-Iwaniuk N, Dziemiańczyk-Pakieła D, Nowaszewska BK, Celińska-Janowicz K, Miltyk W
Curr Drug Targets 2019;20(3):302-315. doi: 10.2174/1389450119666180803121737. PMID: 30073924
Reid JR, Wheeler SF
Am Fam Physician 2005 Aug 15;72(4):623-30. PMID: 16127951
Kvale PA, Ranga V, Kopacz M, Cox F, Magilligan DJ, Davila JC
South Med J 1977 Oct;70 Suppl 1:64-8. doi: 10.1097/00007611-197710001-00018. PMID: 333608

Prognosis

Muller C, Rao VL
Gastrointest Endosc Clin N Am 2022 Apr;32(2):371-384. Epub 2022 Feb 23 doi: 10.1016/j.giec.2021.12.012. PMID: 35361341
Hakami OA, Ahmed S, Karavitaki N
Best Pract Res Clin Endocrinol Metab 2021 Jan;35(1):101521. Epub 2021 Mar 15 doi: 10.1016/j.beem.2021.101521. PMID: 33766428
Daly AF, Beckers A
Endocrinol Metab Clin North Am 2020 Sep;49(3):347-355. Epub 2020 Jun 10 doi: 10.1016/j.ecl.2020.04.002. PMID: 32741475
Wang P, Berzin TM, Glissen Brown JR, Bharadwaj S, Becq A, Xiao X, Liu P, Li L, Song Y, Zhang D, Li Y, Xu G, Tu M, Liu X
Gut 2019 Oct;68(10):1813-1819. Epub 2019 Feb 27 doi: 10.1136/gutjnl-2018-317500. PMID: 30814121Free PMC Article
Brenner H, Kloor M, Pox CP
Lancet 2014 Apr 26;383(9927):1490-1502. Epub 2013 Nov 11 doi: 10.1016/S0140-6736(13)61649-9. PMID: 24225001

Clinical prediction guides

Kezlarian B, Lin O
Acta Cytol 2021;65(4):324-329. Epub 2020 Dec 16 doi: 10.1159/000512097. PMID: 33326953Free PMC Article
Schieda N, Siegelman ES
AJR Am J Roentgenol 2017 Jun;208(6):1206-1217. Epub 2017 Feb 22 doi: 10.2214/AJR.16.17758. PMID: 28225653
Bateman AC, Shepherd NA
J Clin Pathol 2015 Aug;68(8):585-91. Epub 2015 Apr 30 doi: 10.1136/jclinpath-2015-203016. PMID: 25934843
Pendharkar AV, Sussman ES, Ho AL, Hayden Gephart MG, Katznelson L
Neurosurg Focus 2015 Feb;38(2):E13. doi: 10.3171/2014.10.FOCUS14682. PMID: 25639315
Amin W, Parwani AV
Pathol Res Pract 2010 Oct 15;206(10):659-62. Epub 2010 Jul 8 doi: 10.1016/j.prp.2010.06.001. PMID: 20619548

Recent systematic reviews

Hassan C, Spadaccini M, Mori Y, Foroutan F, Facciorusso A, Gkolfakis P, Tziatzios G, Triantafyllou K, Antonelli G, Khalaf K, Rizkala T, Vandvik PO, Fugazza A, Rondonotti E, Glissen-Brown JR, Kamba S, Maida M, Correale L, Bhandari P, Jover R, Sharma P, Rex DK, Repici A
Ann Intern Med 2023 Sep;176(9):1209-1220. Epub 2023 Aug 29 doi: 10.7326/M22-3678. PMID: 37639719
Hassan C, Spadaccini M, Iannone A, Maselli R, Jovani M, Chandrasekar VT, Antonelli G, Yu H, Areia M, Dinis-Ribeiro M, Bhandari P, Sharma P, Rex DK, Rösch T, Wallace M, Repici A
Gastrointest Endosc 2021 Jan;93(1):77-85.e6. Epub 2020 Jun 26 doi: 10.1016/j.gie.2020.06.059. PMID: 32598963
Kashida H
Dig Endosc 2019 Jan;31(1):16-23. Epub 2018 Sep 30 doi: 10.1111/den.13263. PMID: 30151942Free PMC Article
Peraza AJ, Wright J, Gómez R
J Craniomaxillofac Surg 2017 Oct;45(10):1754-1758. Epub 2017 Aug 3 doi: 10.1016/j.jcms.2017.07.020. PMID: 28890252
Bailie L, Loughrey MB, Coleman HG
Gastroenterology 2017 Jan;152(1):92-104. Epub 2016 Sep 14 doi: 10.1053/j.gastro.2016.09.003. PMID: 27639804

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...