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Alveolar Ridge Squamous Cell Carcinoma

MedGen UID:
1749749
•Concept ID:
C5418783
•
Neoplastic Process

Definition

Squamous cell carcinoma arising from the upper or lower alveolar ridge. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAlveolar Ridge Squamous Cell Carcinoma

Professional guidelines

PubMed

AHNS Series: Do you know your guidelines? Evidence-based management of oral cavity cancers.
Gill A, Vasan N, Givi B, Joshi A
Head Neck 2018 Feb;40(2):406-416. Epub 2017 Dec 5 doi: 10.1002/hed.25024. PMID: 29206324
Management of clinically negative neck in maxillary carcinoma.
Valentini V, Terenzi V, Battisti A, Cassoni A, Anelli A, Priore P, Petrinca P
J Craniofac Surg 2010 May;21(3):759-62. doi: 10.1097/SCS.0b013e3181d878d1. PMID: 20485042
Results of treatment for squamous carcinoma of the lower gum.
Byers RM, Newman R, Russell N, Yue A
Cancer 1981 May 1;47(9):2236-8. doi: 10.1002/1097-0142(19810501)47:9<2236::aid-cncr2820470922>3.0.co;2-c. PMID: 7226119

Recent clinical studies

Etiology

Patterns of recurrence in patients undergoing curative treatment for maxillary alveolus squamous cell carcinoma.
Farooq S, Zubair F, McMahon J
Br J Oral Maxillofac Surg 2023 Oct;61(8):563-566. Epub 2023 Jul 27 doi: 10.1016/j.bjoms.2023.07.005. PMID: 37633766
Basaloid squamous cell carcinoma: a 31-year retrospective study and analysis of 214 cases reported in the literature.
Schuch LF, Nóbrega KHS, Gomes APN, Vasconcelos ACU
Oral Maxillofac Surg 2020 Mar;24(1):103-108. Epub 2020 Jan 8 doi: 10.1007/s10006-020-00828-9. PMID: 31912260
Reconstruction of Anterior Mandible and Mouth Floor Using the Myofascial Iliac Crest Free Flap After Tumor Resection.
Xu H, Gao C, Tao Y, Yang X, Shang W, Song K
Ann Plast Surg 2019 Apr;82(4):411-414. doi: 10.1097/SAP.0000000000001649. PMID: 30557181
Elective neck dissection versus observation for cN0 neck of squamous cell carcinoma primarily located in the maxillary gingiva and alveolar ridge: a retrospective study of 129 cases.
Feng Z, Li JN, Li CZ, Guo CB
Oral Surg Oral Med Oral Pathol Oral Radiol 2013 Nov;116(5):556-61. doi: 10.1016/j.oooo.2013.07.011. PMID: 24119520
Mandibular invasion by oral squamous cell carcinoma. Clinical aspects.
Müller H, Slootweg PJ
J Craniomaxillofac Surg 1990 Feb;18(2):80-4. doi: 10.1016/s1010-5182(05)80203-3. PMID: 2312743

Diagnosis

Dyskeratosis congenita and squamous cell carcinoma of the mandibular alveolar ridge.
Manfuso A, Risitano AM, Copelli C
BMJ Case Rep 2021 May 11;14(5) doi: 10.1136/bcr-2021-242459. PMID: 33975847Free PMC Article
Basaloid squamous cell carcinoma: a 31-year retrospective study and analysis of 214 cases reported in the literature.
Schuch LF, Nóbrega KHS, Gomes APN, Vasconcelos ACU
Oral Maxillofac Surg 2020 Mar;24(1):103-108. Epub 2020 Jan 8 doi: 10.1007/s10006-020-00828-9. PMID: 31912260
Congenital epulis.
Merglová V, Mukensnabl P, Andrle P
BMJ Case Rep 2012 Jul 9;2012 doi: 10.1136/bcr.01.2012.5483. PMID: 22778448Free PMC Article
Intraoral molluscum contagiosum imitating a squamous-cell carcinoma in an immunocompetent person--case report and review of the literature.
Scherer P, Fries J, Mischkowski RA, Neugebauer J, Scheer M, Zöller JE
Int J Oral Maxillofac Surg 2009 Jul;38(7):802-5. Epub 2009 Mar 17 doi: 10.1016/j.ijom.2009.01.019. PMID: 19282150
Röntgenological diagnosis.
Nortjé CJ
J Dent Assoc S Afr 1980 Mar;35(3):177-8. PMID: 6935792

Therapy

No survival benefit in never-smoker never-drinker patients with oral cavity cancer.
Yan EZ, Wahle BM, Nakken ER, Chidambaram S, Getz K, Thorstad WL, Zevallos JP, Mazul AL
Head Neck 2023 Mar;45(3):567-577. Epub 2022 Dec 16 doi: 10.1002/hed.27266. PMID: 36524736Free PMC Article
Postoperative radiotherapy is associated with improved overall survival for alveolar ridge squamous cell carcinoma with adverse pathologic features.
Jacobs CD, Williamson H, Barak I, Rocke DJ, Kahmke RR, Suneja G, Mowery YM
Head Neck 2021 Jan;43(1):203-211. Epub 2020 Sep 23 doi: 10.1002/hed.26475. PMID: 32969107Free PMC Article
Reconstruction of mandibular defects following tumor ablation by vertical distraction osteogenesis using intraosseous distraction devices.
Kunkel M, Wahlmann U, Reichert TE, Wegener J, Wagner W
Clin Oral Implants Res 2005 Feb;16(1):89-97. doi: 10.1111/j.1600-0501.2004.01073.x. PMID: 15642035
3-D reconstruction of Ir-192 implant dosimetry for irradiating gingival carcinoma on the mandibular alveolar ridge.
Parsai E, Ayyangar K, Bowman D, Huber B, Dobelbower RR
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995 Jun;79(6):787-92. doi: 10.1016/s1079-2104(05)80317-8. PMID: 7621040
Nasolabial flap for the reconstruction of defects of the floor of the mouth.
Ioannides C, Fossion E
Int J Oral Maxillofac Surg 1991 Feb;20(1):40-3. doi: 10.1016/s0901-5027(05)80694-0. PMID: 2019782

Prognosis

Patterns of recurrence in patients undergoing curative treatment for maxillary alveolus squamous cell carcinoma.
Farooq S, Zubair F, McMahon J
Br J Oral Maxillofac Surg 2023 Oct;61(8):563-566. Epub 2023 Jul 27 doi: 10.1016/j.bjoms.2023.07.005. PMID: 37633766
Reconstruction of Anterior Mandible and Mouth Floor Using the Myofascial Iliac Crest Free Flap After Tumor Resection.
Xu H, Gao C, Tao Y, Yang X, Shang W, Song K
Ann Plast Surg 2019 Apr;82(4):411-414. doi: 10.1097/SAP.0000000000001649. PMID: 30557181
Elective neck dissection versus observation for cN0 neck of squamous cell carcinoma primarily located in the maxillary gingiva and alveolar ridge: a retrospective study of 129 cases.
Feng Z, Li JN, Li CZ, Guo CB
Oral Surg Oral Med Oral Pathol Oral Radiol 2013 Nov;116(5):556-61. doi: 10.1016/j.oooo.2013.07.011. PMID: 24119520
Risk factors affect the survival outcome of hard palatal and maxillary alveolus squamous cell carcinoma: 10-year review in a tertiary referral center.
Wang TC, Hua CH, Lin CC, Tsou YA, Tseng HC, Tsai MH
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010 Jul;110(1):11-7. Epub 2010 Mar 17 doi: 10.1016/j.tripleo.2009.11.035. PMID: 20299251
The local prognosis after radical radiotherapy for squamous carcinoma of the alveolus and of the floor of the mouth.
Porter EH
Clin Radiol 1971 Jan;22(1):139-43. doi: 10.1016/s0009-9260(71)80041-7. PMID: 4994560

Clinical prediction guides

Patterns of recurrence in patients undergoing curative treatment for maxillary alveolus squamous cell carcinoma.
Farooq S, Zubair F, McMahon J
Br J Oral Maxillofac Surg 2023 Oct;61(8):563-566. Epub 2023 Jul 27 doi: 10.1016/j.bjoms.2023.07.005. PMID: 37633766
Prognostic factors from squamous cell carcinoma of the hard palate, gingiva and upper alveolar ridge.
Kovalski LNS, Zanella VG, Jardim LC, Só BB, Girardi FM, Kroef RG, Barra MB, Carrard VC, Martins MD, Martins MAT
Braz Oral Res 2022;36:e058. Epub 2022 May 2 doi: 10.1590/1807-3107bor-2022.vol36.0058. PMID: 36507745
Malignant lesions in the anterior maxilla.
MacDonald D, Martin M, Nguyen C
Clin Radiol 2020 Jul;75(7):497-506. Epub 2019 Oct 31 doi: 10.1016/j.crad.2019.09.133. PMID: 31677882
Reconstruction of Anterior Mandible and Mouth Floor Using the Myofascial Iliac Crest Free Flap After Tumor Resection.
Xu H, Gao C, Tao Y, Yang X, Shang W, Song K
Ann Plast Surg 2019 Apr;82(4):411-414. doi: 10.1097/SAP.0000000000001649. PMID: 30557181
Elective neck dissection versus observation for cN0 neck of squamous cell carcinoma primarily located in the maxillary gingiva and alveolar ridge: a retrospective study of 129 cases.
Feng Z, Li JN, Li CZ, Guo CB
Oral Surg Oral Med Oral Pathol Oral Radiol 2013 Nov;116(5):556-61. doi: 10.1016/j.oooo.2013.07.011. PMID: 24119520

Recent systematic reviews

Systematic review and meta-analysis of cervical metastases in oral maxillary squamous cell carcinoma.
Chia C, Key S, Hasan Z, Virk S, Riffat F
Cancer Rep (Hoboken) 2021 Dec;4(6):e1410. Epub 2021 May 8 doi: 10.1002/cnr2.1410. PMID: 33963809Free PMC Article
When should elective neck dissection be performed in maxillary gingival and alveolar squamous cell carcinoma with a cN0 neck? A systematic review.
Tang L, Leung YY
Int J Oral Maxillofac Surg 2016 Nov;45(11):1358-1365. Epub 2016 Jun 8 doi: 10.1016/j.ijom.2016.05.021. PMID: 27289248

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