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Locally Advanced Endometrial Adenocarcinoma

MedGen UID:
1765231
Concept ID:
C5420540
Neoplastic Process

Definition

Endometrial adenocarcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Endometrial Adenocarcinoma

Professional guidelines

PubMed

Morcet-Delattre R, Espenel S, Tas P, Chargari C, Escande A
Cancer Radiother 2023 Dec;27(8):778-788. Epub 2023 Nov 2 doi: 10.1016/j.canrad.2023.08.006. PMID: 37925347
Bogliolo S, Gardella B, Dominoni M, Musacchi V, Cassani C, Zanellini F, De Silvestri A, Gaggero CR, Babilonti L, Spinillo A
Arch Gynecol Obstet 2016 Apr;293(4):701-8. Epub 2015 Dec 15 doi: 10.1007/s00404-015-3974-9. PMID: 26671487
Reifenstein EC Jr
Gynecol Oncol 1974 Aug;2(2-3):377-414. doi: 10.1016/0090-8258(74)90029-8. PMID: 4616884

Recent clinical studies

Etiology

Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
J Gynecol Oncol 2023 Sep;34(5):e85. Epub 2023 Aug 8 doi: 10.3802/jgo.2023.34.e85. PMID: 37593813Free PMC Article
Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
Int J Gynaecol Obstet 2023 Aug;162(2):383-394. Epub 2023 Jun 20 doi: 10.1002/ijgo.14923. PMID: 37337978
Pors J, Segura S, Chiu DS, Almadani N, Ren H, Fix DJ, Howitt BE, Kolin D, McCluggage WG, Mirkovic J, Gilks B, Park KJ, Hoang L
Am J Surg Pathol 2021 Apr 1;45(4):498-506. doi: 10.1097/PAS.0000000000001612. PMID: 33165093Free PMC Article
Fader AN, Roque DM, Siegel E, Buza N, Hui P, Abdelghany O, Chambers S, Secord AA, Havrilesky L, O'Malley DM, Backes FJ, Nevadunsky N, Edraki B, Pikaart D, Lowery W, ElSahwi K, Celano P, Bellone S, Azodi M, Litkouhi B, Ratner E, Silasi DA, Schwartz PE, Santin AD
Clin Cancer Res 2020 Aug 1;26(15):3928-3935. Epub 2020 Jun 29 doi: 10.1158/1078-0432.CCR-20-0953. PMID: 32601075Free PMC Article
Deli T, Orosz M, Jakab A
Pathol Oncol Res 2020 Jan;26(1):63-78. Epub 2019 Jan 8 doi: 10.1007/s12253-018-00569-x. PMID: 30617760Free PMC Article

Diagnosis

Morcet-Delattre R, Espenel S, Tas P, Chargari C, Escande A
Cancer Radiother 2023 Dec;27(8):778-788. Epub 2023 Nov 2 doi: 10.1016/j.canrad.2023.08.006. PMID: 37925347
Köbel M, Kang EY
Int J Gynecol Pathol 2021 Jan;40(1):32-40. doi: 10.1097/PGP.0000000000000725. PMID: 33290354
Buza N
Int J Gynecol Pathol 2021 Jan;40(1):17-23. doi: 10.1097/PGP.0000000000000711. PMID: 33290351
Fader AN, Roque DM, Siegel E, Buza N, Hui P, Abdelghany O, Chambers S, Secord AA, Havrilesky L, O'Malley DM, Backes FJ, Nevadunsky N, Edraki B, Pikaart D, Lowery W, ElSahwi K, Celano P, Bellone S, Azodi M, Litkouhi B, Ratner E, Silasi DA, Schwartz PE, Santin AD
Clin Cancer Res 2020 Aug 1;26(15):3928-3935. Epub 2020 Jun 29 doi: 10.1158/1078-0432.CCR-20-0953. PMID: 32601075Free PMC Article
Naumann RW
Curr Oncol Rep 2008 Nov;10(6):505-11. doi: 10.1007/s11912-008-0076-x. PMID: 18928665

Therapy

Buza N
Int J Gynecol Pathol 2021 Jan;40(1):17-23. doi: 10.1097/PGP.0000000000000711. PMID: 33290351
Fader AN, Roque DM, Siegel E, Buza N, Hui P, Abdelghany O, Chambers S, Secord AA, Havrilesky L, O'Malley DM, Backes FJ, Nevadunsky N, Edraki B, Pikaart D, Lowery W, ElSahwi K, Celano P, Bellone S, Azodi M, Litkouhi B, Ratner E, Silasi DA, Schwartz PE, Santin AD
Clin Cancer Res 2020 Aug 1;26(15):3928-3935. Epub 2020 Jun 29 doi: 10.1158/1078-0432.CCR-20-0953. PMID: 32601075Free PMC Article
Deli T, Orosz M, Jakab A
Pathol Oncol Res 2020 Jan;26(1):63-78. Epub 2019 Jan 8 doi: 10.1007/s12253-018-00569-x. PMID: 30617760Free PMC Article
Quinn MA, Campbell JJ
Gynecol Oncol 1989 Jan;32(1):1-3. doi: 10.1016/0090-8258(89)90839-1. PMID: 2909443
Thigpen T, Vance RB, Balducci L, Blessing J
Cancer 1981 Jul 15;48(2 Suppl):658-65. doi: 10.1002/1097-0142(19810715)48:1+<658::aid-cncr2820481334>3.0.co;2-r. PMID: 7023669

Prognosis

Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
J Gynecol Oncol 2023 Sep;34(5):e85. Epub 2023 Aug 8 doi: 10.3802/jgo.2023.34.e85. PMID: 37593813Free PMC Article
Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
Int J Gynaecol Obstet 2023 Aug;162(2):383-394. Epub 2023 Jun 20 doi: 10.1002/ijgo.14923. PMID: 37337978
Köbel M, Kang EY
Int J Gynecol Pathol 2021 Jan;40(1):32-40. doi: 10.1097/PGP.0000000000000725. PMID: 33290354
Fader AN, Roque DM, Siegel E, Buza N, Hui P, Abdelghany O, Chambers S, Secord AA, Havrilesky L, O'Malley DM, Backes FJ, Nevadunsky N, Edraki B, Pikaart D, Lowery W, ElSahwi K, Celano P, Bellone S, Azodi M, Litkouhi B, Ratner E, Silasi DA, Schwartz PE, Santin AD
Clin Cancer Res 2020 Aug 1;26(15):3928-3935. Epub 2020 Jun 29 doi: 10.1158/1078-0432.CCR-20-0953. PMID: 32601075Free PMC Article
Berman ML, Ballon SC, Lagasse LD, Watring WG
Am J Obstet Gynecol 1980 Mar 1;136(5):679-88. doi: 10.1016/0002-9378(80)91024-8. PMID: 7355948

Clinical prediction guides

Narva S, Polo-Kantola P, Oksa S, Kallio J, Huvila J, Rissanen T, Hynninen J, Hietanen S, Joutsiniemi T
Eur J Surg Oncol 2024 Jun;50(6):108317. Epub 2024 Apr 1 doi: 10.1016/j.ejso.2024.108317. PMID: 38581756
Ross DS, Devereaux KA, Jin C, Lin DY, Zhang Y, Marra A, Makker V, Weigelt B, Ellenson LH, Chui MH
Mod Pathol 2022 Jul;35(7):962-971. Epub 2021 Dec 31 doi: 10.1038/s41379-021-00997-2. PMID: 34972830Free PMC Article
Larish A, Mariani A, Langstraat C
In Vivo 2021 Mar-Apr;35(2):671-680. doi: 10.21873/invivo.12307. PMID: 33622859Free PMC Article
Köbel M, Kang EY
Int J Gynecol Pathol 2021 Jan;40(1):32-40. doi: 10.1097/PGP.0000000000000725. PMID: 33290354
Baiocchi G, Cestari LA, Macedo MP, Oliveira RA, Fukazawa EM, Faloppa CC, Kumagai LY, Badiglian-Filho L, Menezes AN, Cunha IW, Soares FA
J Surg Oncol 2011 Sep 1;104(3):250-4. Epub 2011 Apr 6 doi: 10.1002/jso.21940. PMID: 21472733

Recent systematic reviews

Bogliolo S, Gardella B, Dominoni M, Musacchi V, Cassani C, Zanellini F, De Silvestri A, Gaggero CR, Babilonti L, Spinillo A
Arch Gynecol Obstet 2016 Apr;293(4):701-8. Epub 2015 Dec 15 doi: 10.1007/s00404-015-3974-9. PMID: 26671487
Vale CL, Tierney J, Bull SJ, Symonds PR
Cochrane Database Syst Rev 2012 Aug 15;2012(8):CD003915. doi: 10.1002/14651858.CD003915.pub4. PMID: 22895938Free PMC Article
Humber CE, Tierney JF, Symonds RP, Collingwood M, Kirwan J, Williams C, Green JA
Ann Oncol 2007 Mar;18(3):409-20. Epub 2006 Dec 5 doi: 10.1093/annonc/mdl417. PMID: 17150999
Humber C, Tierney J, Symonds P, Collingwood M, Kirwan J, Williams C, Green J
Cochrane Database Syst Rev 2005 Oct 19;(4):CD003915. doi: 10.1002/14651858.CD003915.pub3. PMID: 16235346
Humber C, Tierney J, Symonds P, Collingwood M, Kirwan J, Williams C, Green J
Cochrane Database Syst Rev 2005 Jul 20;(3):CD003915. doi: 10.1002/14651858.CD003915.pub2. PMID: 16034916

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