U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Sleep-related breathing disorders

MedGen UID:
1853216
•Concept ID:
C5872985
•
Disease or Syndrome
Synonym: Difficult respiration during sleep
 
HPO: HP:5200283

Definition

Conditions of abnormal and difficult respiration during sleep, including chronic snoring and sleep apnea. [from HPO]

Professional guidelines

PubMed

The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023.
Riemann D, Espie CA, Altena E, Arnardottir ES, Baglioni C, Bassetti CLA, Bastien C, Berzina N, Bjorvatn B, Dikeos D, Dolenc Groselj L, Ellis JG, Garcia-Borreguero D, Geoffroy PA, Gjerstad M, Gonçalves M, Hertenstein E, Hoedlmoser K, Hion T, Holzinger B, Janku K, Jansson-Fröjmark M, Järnefelt H, Jernelöv S, Jennum PJ, Khachatryan S, Krone L, Kyle SD, Lancee J, Leger D, Lupusor A, Marques DR, Nissen C, Palagini L, Paunio T, Perogamvros L, Pevernagie D, Schabus M, Shochat T, Szentkiralyi A, Van Someren E, van Straten A, Wichniak A, Verbraecken J, Spiegelhalder K
J Sleep Res 2023 Dec;32(6):e14035. doi: 10.1111/jsr.14035. PMID: 38016484
Obstructive sleep apnea treatment in adults.
Chang HP, Chen YF, Du JK
Kaohsiung J Med Sci 2020 Jan;36(1):7-12. Epub 2019 Sep 12 doi: 10.1002/kjm2.12130. PMID: 31512369
European guideline for the diagnosis and treatment of insomnia.
Riemann D, Baglioni C, Bassetti C, Bjorvatn B, Dolenc Groselj L, Ellis JG, Espie CA, Garcia-Borreguero D, Gjerstad M, Gonçalves M, Hertenstein E, Jansson-Fröjmark M, Jennum PJ, Leger D, Nissen C, Parrino L, Paunio T, Pevernagie D, Verbraecken J, Weeß HG, Wichniak A, Zavalko I, Arnardottir ES, Deleanu OC, Strazisar B, Zoetmulder M, Spiegelhalder K
J Sleep Res 2017 Dec;26(6):675-700. Epub 2017 Sep 5 doi: 10.1111/jsr.12594. PMID: 28875581

Recent clinical studies

Etiology

Sleep-related breathing disorders and pulmonary hypertension.
Adir Y, Humbert M, Chaouat A
Eur Respir J 2021 Jan;57(1) Epub 2021 Jan 5 doi: 10.1183/13993003.02258-2020. PMID: 32747397
Polysomnography.
Rundo JV, Downey R 3rd
Handb Clin Neurol 2019;160:381-392. doi: 10.1016/B978-0-444-64032-1.00025-4. PMID: 31277862
European guideline for the diagnosis and treatment of insomnia.
Riemann D, Baglioni C, Bassetti C, Bjorvatn B, Dolenc Groselj L, Ellis JG, Espie CA, Garcia-Borreguero D, Gjerstad M, Gonçalves M, Hertenstein E, Jansson-Fröjmark M, Jennum PJ, Leger D, Nissen C, Parrino L, Paunio T, Pevernagie D, Verbraecken J, Weeß HG, Wichniak A, Zavalko I, Arnardottir ES, Deleanu OC, Strazisar B, Zoetmulder M, Spiegelhalder K
J Sleep Res 2017 Dec;26(6):675-700. Epub 2017 Sep 5 doi: 10.1111/jsr.12594. PMID: 28875581
Sleep-Disordered Breathing.
Foldvary-Schaefer NR, Waters TE
Continuum (Minneap Minn) 2017 Aug;23(4, Sleep Neurology):1093-1116. doi: 10.1212/01.CON.0000522245.13784.f6. PMID: 28777178
A review of sleep disorders and melatonin.
Xie Z, Chen F, Li WA, Geng X, Li C, Meng X, Feng Y, Liu W, Yu F
Neurol Res 2017 Jun;39(6):559-565. Epub 2017 May 1 doi: 10.1080/01616412.2017.1315864. PMID: 28460563

Diagnosis

The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023.
Riemann D, Espie CA, Altena E, Arnardottir ES, Baglioni C, Bassetti CLA, Bastien C, Berzina N, Bjorvatn B, Dikeos D, Dolenc Groselj L, Ellis JG, Garcia-Borreguero D, Geoffroy PA, Gjerstad M, Gonçalves M, Hertenstein E, Hoedlmoser K, Hion T, Holzinger B, Janku K, Jansson-Fröjmark M, Järnefelt H, Jernelöv S, Jennum PJ, Khachatryan S, Krone L, Kyle SD, Lancee J, Leger D, Lupusor A, Marques DR, Nissen C, Palagini L, Paunio T, Perogamvros L, Pevernagie D, Schabus M, Shochat T, Szentkiralyi A, Van Someren E, van Straten A, Wichniak A, Verbraecken J, Spiegelhalder K
J Sleep Res 2023 Dec;32(6):e14035. doi: 10.1111/jsr.14035. PMID: 38016484
Sleep in Parkinson's disease.
Stefani A, Högl B
Neuropsychopharmacology 2020 Jan;45(1):121-128. Epub 2019 Jun 24 doi: 10.1038/s41386-019-0448-y. PMID: 31234200Free PMC Article
Polysomnography.
Rundo JV, Downey R 3rd
Handb Clin Neurol 2019;160:381-392. doi: 10.1016/B978-0-444-64032-1.00025-4. PMID: 31277862
European guideline for the diagnosis and treatment of insomnia.
Riemann D, Baglioni C, Bassetti C, Bjorvatn B, Dolenc Groselj L, Ellis JG, Espie CA, Garcia-Borreguero D, Gjerstad M, Gonçalves M, Hertenstein E, Jansson-Fröjmark M, Jennum PJ, Leger D, Nissen C, Parrino L, Paunio T, Pevernagie D, Verbraecken J, Weeß HG, Wichniak A, Zavalko I, Arnardottir ES, Deleanu OC, Strazisar B, Zoetmulder M, Spiegelhalder K
J Sleep Res 2017 Dec;26(6):675-700. Epub 2017 Sep 5 doi: 10.1111/jsr.12594. PMID: 28875581
International classification of sleep disorders-third edition: highlights and modifications.
Sateia MJ
Chest 2014 Nov;146(5):1387-1394. doi: 10.1378/chest.14-0970. PMID: 25367475

Therapy

The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023.
Riemann D, Espie CA, Altena E, Arnardottir ES, Baglioni C, Bassetti CLA, Bastien C, Berzina N, Bjorvatn B, Dikeos D, Dolenc Groselj L, Ellis JG, Garcia-Borreguero D, Geoffroy PA, Gjerstad M, Gonçalves M, Hertenstein E, Hoedlmoser K, Hion T, Holzinger B, Janku K, Jansson-Fröjmark M, Järnefelt H, Jernelöv S, Jennum PJ, Khachatryan S, Krone L, Kyle SD, Lancee J, Leger D, Lupusor A, Marques DR, Nissen C, Palagini L, Paunio T, Perogamvros L, Pevernagie D, Schabus M, Shochat T, Szentkiralyi A, Van Someren E, van Straten A, Wichniak A, Verbraecken J, Spiegelhalder K
J Sleep Res 2023 Dec;32(6):e14035. doi: 10.1111/jsr.14035. PMID: 38016484
Sleep Consequences of Prader-Willi Syndrome.
Itani R, Gillett ES, Perez IA
Curr Neurol Neurosci Rep 2023 Mar;23(3):25-32. Epub 2023 Feb 15 doi: 10.1007/s11910-023-01254-6. PMID: 36790642Free PMC Article
Increasingly Familiar Breathing Pattern in an Unfamiliar Population. Sleep-related Breathing Disorders in High-Risk Patients.
Mohon RT, Khan E, DelRosso LM
Ann Am Thorac Soc 2020 Jul;17(7):895-898. doi: 10.1513/AnnalsATS.201911-853CC. PMID: 32609031
European guideline for the diagnosis and treatment of insomnia.
Riemann D, Baglioni C, Bassetti C, Bjorvatn B, Dolenc Groselj L, Ellis JG, Espie CA, Garcia-Borreguero D, Gjerstad M, Gonçalves M, Hertenstein E, Jansson-Fröjmark M, Jennum PJ, Leger D, Nissen C, Parrino L, Paunio T, Pevernagie D, Verbraecken J, Weeß HG, Wichniak A, Zavalko I, Arnardottir ES, Deleanu OC, Strazisar B, Zoetmulder M, Spiegelhalder K
J Sleep Res 2017 Dec;26(6):675-700. Epub 2017 Sep 5 doi: 10.1111/jsr.12594. PMID: 28875581
Sleep-related breathing disorders. 5. Nasal continuous positive airway pressure treatment for obstructive sleep apnoea.
Grunstein RR
Thorax 1995 Oct;50(10):1106-13. doi: 10.1136/thx.50.10.1106. PMID: 7491563Free PMC Article

Prognosis

Application of artificial intelligence in the diagnosis of sleep apnea.
Bazoukis G, Bollepalli SC, Chung CT, Li X, Tse G, Bartley BL, Batool-Anwar S, Quan SF, Armoundas AA
J Clin Sleep Med 2023 Jul 1;19(7):1337-1363. doi: 10.5664/jcsm.10532. PMID: 36856067Free PMC Article
ECG and Heart Rate Variability in Sleep-Related Breathing Disorders.
Qin H, Vaquerizo-Villar F, Steenbergen N, Kraemer JF, Penzel T
Adv Exp Med Biol 2022;1384:159-183. doi: 10.1007/978-3-031-06413-5_10. PMID: 36217084
Sleep-related Breathing Disorders in Children with Asthma: Impact on Asthma Control.
Bilgin N, Ozdogan S, Kaya A, Yildirmak Y
J Coll Physicians Surg Pak 2022 Apr;32(4):473-477. doi: 10.29271/jcpsp.2022.04.473. PMID: 35330520
Review of Narcolepsy and Other Common Sleep Disorders in Children.
Nallu S, Guerrero GY, Lewis-Croswell J, Wittine LM
Adv Pediatr 2019 Aug;66:147-159. Epub 2019 Apr 25 doi: 10.1016/j.yapd.2019.03.008. PMID: 31230690
Uvulopalatopharyngoplasty for obstructive sleep-related breathing disorders: one-year follow up.
Itasaka Y, Miyazaki S, Tanaka T, Ishikawa K
Psychiatry Clin Neurosci 2001 Jun;55(3):261-2. doi: 10.1046/j.1440-1819.2001.00851.x. PMID: 11422867

Clinical prediction guides

Application of artificial intelligence in the diagnosis of sleep apnea.
Bazoukis G, Bollepalli SC, Chung CT, Li X, Tse G, Bartley BL, Batool-Anwar S, Quan SF, Armoundas AA
J Clin Sleep Med 2023 Jul 1;19(7):1337-1363. doi: 10.5664/jcsm.10532. PMID: 36856067Free PMC Article
Sleep-related breathing disorders in diaphragmatic pathologies.
Sarac S, Salturk C, Oruc O, Metin SK, Bayram S, Karakurt Z, Yalcınkaya I
Sleep Breath 2022 Jun;26(2):959-963. Epub 2021 Jun 30 doi: 10.1007/s11325-021-02422-z. PMID: 34191224
Sleep-related breathing disorders and pulmonary hypertension.
Adir Y, Humbert M, Chaouat A
Eur Respir J 2021 Jan;57(1) Epub 2021 Jan 5 doi: 10.1183/13993003.02258-2020. PMID: 32747397
Sleep-related disorders and their relationship with MRI findings in multiple sclerosis.
Foschi M, Rizzo G, Liguori R, Avoni P, Mancinelli L, Lugaresi A, Ferini-Strambi L
Sleep Med 2019 Apr;56:90-97. Epub 2019 Jan 21 doi: 10.1016/j.sleep.2019.01.010. PMID: 30803830
Tension-type headache and sleep.
Rains JC, Davis RE, Smitherman TA
Curr Neurol Neurosci Rep 2015;15(2):520. doi: 10.1007/s11910-014-0520-2. PMID: 25475495

Recent systematic reviews

Pulmonary hypertension in patients affected by sleep-related breathing disorders: up to date from the literature.
Battaglia E, Compalati E, Mapelli L, Lax A, Pierucci P, Solidoro P, Banfi P
Minerva Med 2024 Dec;115(6):671-688. Epub 2024 Jul 17 doi: 10.23736/S0026-4806.24.09112-2. PMID: 39016524
Sleep disorders in Down syndrome: a systematic review.
Santos RA, Costa LH, Linhares RC, Pradella-Hallinan M, Coelho FMS, Oliveira GDP
Arq Neuropsiquiatr 2022 Apr;80(4):424-443. doi: 10.1590/0004-282X-ANP-2021-0242. PMID: 35293557Free PMC Article
Socioeconomic disparities in obstructive sleep apnea: a systematic review of empirical research.
Etindele Sosso FA, Matos E
Sleep Breath 2021 Dec;25(4):1729-1739. Epub 2021 Jan 16 doi: 10.1007/s11325-020-02274-z. PMID: 33452999
Beyond the growth delay in children with sleep-related breathing disorders: a systematic review.
Zaffanello M, Piacentini G, La Grutta S
Panminerva Med 2020 Sep;62(3):164-175. Epub 2020 Apr 23 doi: 10.23736/S0031-0808.20.03904-X. PMID: 32329330
Effect of cardiac pacing on sleep-related breathing disorders: a systematic review.
Anastasopoulos DL, Chalkias A, Iakovidou N, Xanthos T
Heart Fail Rev 2016 Sep;21(5):579-90. doi: 10.1007/s10741-016-9558-3. PMID: 27112558

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...