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Retinal vascular occlusion

MedGen UID:: 19762
•Concept ID:: C0035326
•: Disease or Syndrome

Synonyms:	Retinal Vascular Occlusion; retinal vascular occlusion; retinal vascular occlusion, unspecified
SNOMED CT:	Retinal vascular occlusion (73757007)

Monarch Initiative:	MONDO:0002089

Definition

An occlusion of the retinal vasculature. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVRetinal vascular occlusion

Disease
- Disorder by Site
  - Disorder of orbital region
    - Non-Neoplastic Eye Disorder
      - Non-Neoplastic Retinal Disorder
        Retinal vascular disorder
        Retinal vascular occlusion
        Retinal arterial occlusion
        Branch retinal artery occlusion
        Central retinal artery occlusion
        Cilioretinal artery occlusion
        Ophthalmic artery occlusion
        Partial arterial retinal occlusion
        Susac syndrome
        Transient retinal arterial occlusion
        Retinal vein occlusion
        Branch retinal vein occlusion
        Central retinal vein occlusion
        Hemiretinal vein occlusion
        Partial retinal vein occlusion

Professional guidelines

PubMed

Expert Opinion on Management of Intraocular Inflammation, Retinal Vasculitis, and Vascular Occlusion after Brolucizumab Treatment.

Baumal CR, Bodaghi B, Singer M, Tanzer DJ, Seres A, Joshi MR, Feltgen N, Gale R
Ophthalmol Retina 2021 Jun;5(6):519-527. Epub 2020 Sep 29 doi: 10.1016/j.oret.2020.09.020. PMID: 33007521

Intravitreal steroids for the treatment of retinal diseases.

Sarao V, Veritti D, Boscia F, Lanzetta P
ScientificWorldJournal 2014;2014:989501. Epub 2014 Jan 8 doi: 10.1155/2014/989501. PMID: 24526927 Free PMC Article

Wegener's granulomatosis: clinical manifestations, differential diagnosis, and management of ocular and systemic disease.

Tarabishy AB, Schulte M, Papaliodis GN, Hoffman GS
Surv Ophthalmol 2010 Sep-Oct;55(5):429-44. Epub 2010 Jul 17 doi: 10.1016/j.survophthal.2009.12.003. PMID: 20638092

See all (22)

Recent clinical studies

Etiology

Retinal vascular occlusion and SARS-CoV-2 vaccination.

Vujosevic S, Limoli C, Romano S, Vitale L, Villani E, Nucci P
Graefes Arch Clin Exp Ophthalmol 2022 Nov;260(11):3455-3464. Epub 2022 May 25 doi: 10.1007/s00417-022-05707-5. PMID: 35612613 Free PMC Article

Risk of Inflammation, Retinal Vasculitis, and Retinal Occlusion-Related Events with Brolucizumab: Post Hoc Review of HAWK and HARRIER.

Monés J, Srivastava SK, Jaffe GJ, Tadayoni R, Albini TA, Kaiser PK, Holz FG, Korobelnik JF, Kim IK, Pruente C, Murray TG, Heier JS
Ophthalmology 2021 Jul;128(7):1050-1059. Epub 2020 Nov 15 doi: 10.1016/j.ophtha.2020.11.011. PMID: 33207259

Systemic lupus erythematosus and ocular involvement: an overview.

Dammacco R
Clin Exp Med 2018 May;18(2):135-149. Epub 2017 Dec 14 doi: 10.1007/s10238-017-0479-9. PMID: 29243035

Hypertensive eye disease: a review.

Fraser-Bell S, Symes R, Vaze A
Clin Exp Ophthalmol 2017 Jan;45(1):45-53. Epub 2017 Jan 21 doi: 10.1111/ceo.12905. PMID: 27990740

Cilioretinal artery occlusion.

Stoffelns BM, Laspas P
Klin Monbl Augenheilkd 2015 Apr;232(4):519-24. Epub 2015 Apr 22 doi: 10.1055/s-0034-1396327. PMID: 25902112

See all (151)

Diagnosis

Risk of Inflammation, Retinal Vasculitis, and Retinal Occlusion-Related Events with Brolucizumab: Post Hoc Review of HAWK and HARRIER.

Systemic lupus erythematosus and ocular involvement: an overview.

Dammacco R
Clin Exp Med 2018 May;18(2):135-149. Epub 2017 Dec 14 doi: 10.1007/s10238-017-0479-9. PMID: 29243035

Hypertensive eye disease: a review.

Fraser-Bell S, Symes R, Vaze A
Clin Exp Ophthalmol 2017 Jan;45(1):45-53. Epub 2017 Jan 21 doi: 10.1111/ceo.12905. PMID: 27990740

Acute Vision Loss.

Bagheri N, Mehta S
Prim Care 2015 Sep;42(3):347-61. doi: 10.1016/j.pop.2015.05.010. PMID: 26319342

Cilioretinal artery occlusion.

Stoffelns BM, Laspas P
Klin Monbl Augenheilkd 2015 Apr;232(4):519-24. Epub 2015 Apr 22 doi: 10.1055/s-0034-1396327. PMID: 25902112

See all (158)

Therapy

Efficacy and Safety of Brolucizumab for Diabetic Macular Edema: The KINGFISHER Randomized Clinical Trial.

Singh RP, Barakat MR, Ip MS, Wykoff CC, Eichenbaum DA, Joshi S, Warrow D, Sheth VS, Stefanickova J, Kim YS, He F, Cho GE, Wang Y, Emanuelli A
JAMA Ophthalmol 2023 Dec 1;141(12):1152-1160. doi: 10.1001/jamaophthalmol.2023.5248. PMID: 37971723

Retinal vascular occlusion and SARS-CoV-2 vaccination.

Association between Statins and Retinal Vascular Occlusion: A Population-Based Cohort Study.

Chien CC, Chen PH, Chung CH, Sun CA, Chien WC, Chien KH
Int J Environ Res Public Health 2021 Sep 18;18(18) doi: 10.3390/ijerph18189864. PMID: 34574786 Free PMC Article

Risk of Inflammation, Retinal Vasculitis, and Retinal Occlusion-Related Events with Brolucizumab: Post Hoc Review of HAWK and HARRIER.

Combined retinal vascular occlusion: Demography, clinical features, visual outcome, systemic co-morbidities, and literature review.

Raval V, Nayak S, Saldanha M, Jalali S, Pappuru RR, Narayanan R, Das T
Indian J Ophthalmol 2020 Oct;68(10):2136-2142. doi: 10.4103/ijo.IJO_2116_19. PMID: 32971625 Free PMC Article

See all (108)

Prognosis

Retinal vascular occlusion risks during the COVID-19 pandemic and after SARS-CoV-2 infection.

Park HS, Kim S, Lee CS, Byeon SH, Kim SS, Lee SW, Kim YJ
Sci Rep 2023 Oct 6;13(1):16851. doi: 10.1038/s41598-023-44199-z. PMID: 37803163 Free PMC Article

Plasma lipid levels and risk of retinal vascular occlusion: A genetic study using Mendelian randomization.

Zheng C, Lin Y, Jiang B, Zhu X, Lin Q, Luo W, Tang M, Xie L
Front Endocrinol (Lausanne) 2022;13:954453. Epub 2022 Oct 10 doi: 10.3389/fendo.2022.954453. PMID: 36299452 Free PMC Article

Association between Statins and Retinal Vascular Occlusion: A Population-Based Cohort Study.

Chien CC, Chen PH, Chung CH, Sun CA, Chien WC, Chien KH
Int J Environ Res Public Health 2021 Sep 18;18(18) doi: 10.3390/ijerph18189864. PMID: 34574786 Free PMC Article

Risk of Inflammation, Retinal Vasculitis, and Retinal Occlusion-Related Events with Brolucizumab: Post Hoc Review of HAWK and HARRIER.

Cilioretinal artery occlusion.

Stoffelns BM, Laspas P
Klin Monbl Augenheilkd 2015 Apr;232(4):519-24. Epub 2015 Apr 22 doi: 10.1055/s-0034-1396327. PMID: 25902112

See all (64)

Clinical prediction guides

RETINAL VASCULAR OCCLUSION AND COVID-19 DIAGNOSIS: A Multicenter Population-Based Study.

Li JX, Wei JC, Wang YH, Bair H, Hsu SB, Lin CJ
Retina 2024 Feb 1;44(2):345-352. doi: 10.1097/IAE.0000000000003952. PMID: 37824812

Efficacy and Safety of Brolucizumab for Diabetic Macular Edema: The KINGFISHER Randomized Clinical Trial.

Use of phosphodiesterase 5 inhibitors is not associated with ocular adverse events.

Belladelli F, Li S, Zhang CA, Muncey W, Del Giudice F, Glover F, Seranio N, Basran S, Fallara G, Montorsi F, Salonia A, Eisenberg ML
J Sex Med 2023 Nov 30;20(12):1399-1406. doi: 10.1093/jsxmed/qdad137. PMID: 37861186 Free PMC Article

Plasma lipid levels and risk of retinal vascular occlusion: A genetic study using Mendelian randomization.

Zheng C, Lin Y, Jiang B, Zhu X, Lin Q, Luo W, Tang M, Xie L
Front Endocrinol (Lausanne) 2022;13:954453. Epub 2022 Oct 10 doi: 10.3389/fendo.2022.954453. PMID: 36299452 Free PMC Article

The use of intraocular corticosteroids.

Kiernan DF, Mieler WF
Expert Opin Pharmacother 2009 Oct;10(15):2511-25. doi: 10.1517/14656560903160671. PMID: 19761356

See all (59)

Recent systematic reviews

Systematic review of the ophthalmic complications of robotic-assisted laparoscopic prostatectomy.

Rabinowitz J, Kinnear N, O'Callaghan M, Hennessey D, Shafi F, Fuller A, Ibrahim M, Lane T, Adshead J, Vasdev N
J Robot Surg 2024 Jan 19;18(1):46. doi: 10.1007/s11701-023-01771-z. PMID: 38240959

RISK OF INTRAOCULAR INFLAMMATION AFTER INJECTION OF ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR AGENTS: A Meta-analysis.

Patil NS, Dhoot AS, Popovic MM, Kertes PJ, Muni RH
Retina 2022 Nov 1;42(11):2134-2142. doi: 10.1097/IAE.0000000000003582. PMID: 36269802

Eye disorders other than diabetic retinopathy in patients with diabetes.

Feldman-Billard S, Dupas B
Diabetes Metab 2021 Nov;47(6):101279. Epub 2021 Sep 14 doi: 10.1016/j.diabet.2021.101279. PMID: 34534696

CLINICAL SIGNIFICANCE OF RETINAL VASCULAR OCCLUSION IN MOYAMOYA DISEASE: Case Series and Systematic Review.

Seong HJ, Lee JH, Heo JH, Kim DS, Kim YB, Lee CS
Retina 2021 Sep 1;41(9):1791-1798. doi: 10.1097/IAE.0000000000003181. PMID: 33840794

Inherited and acquired thrombophilia in adults with retinal vascular occlusion: A systematic review and meta-analysis.

Romiti GF, Corica B, Borgi M, Visioli G, Pacella E, Cangemi R, Proietti M, Basili S, Raparelli V
J Thromb Haemost 2020 Dec;18(12):3249-3266. Epub 2020 Oct 6 doi: 10.1111/jth.15068. PMID: 32805772

See all (5)

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Retinal vascular occlusion

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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