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Schizoid personality disorder

MedGen UID:
20662
Concept ID:
C0036339
Mental or Behavioral Dysfunction
Synonyms: Disorder, Schizoid Personality; Disorders, Schizoid Personality; Personalities, Schizoid; Personality Disorder, Schizoid; Personality Disorders, Schizoid; Personality, Schizoid; Schizoid Personalities; Schizoid Personality; Schizoid Personality Disorder; Schizoid Personality Disorders
SNOMED CT: Schizoid personality disorder (52954000)
 
Monarch Initiative: MONDO:0001161

Definition

A disorder characterized by an enduring pattern of extreme social detachment and lack of involvement in interpersonal activities, coupled with emotional coldness. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSchizoid personality disorder

Professional guidelines

PubMed

Borroni S, Masci E, Franzoni C, Somma A, Fossati A
Psychiatry Res 2021 Jan;295:113587. Epub 2020 Nov 24 doi: 10.1016/j.psychres.2020.113587. PMID: 33349435
Ayerbe L, Forgnone I, Foguet-Boreu Q, González E, Addo J, Ayis S
Psychol Med 2018 Dec;48(16):2693-2701. Epub 2018 Mar 1 doi: 10.1017/S0033291718000302. PMID: 29490716
Scheeringa MS
Child Psychiatry Hum Dev 2001 Fall;32(1):71-89. doi: 10.1023/a:1017511714145. PMID: 11579660

Recent clinical studies

Etiology

Attademo L, Bernardini F, Spatuzzi R
Psychiatr Danub 2021 Fall;33(3):261-265. doi: 10.24869/psyd.2021.261. PMID: 34795159
Triebwasser J, Chemerinski E, Roussos P, Siever LJ
J Pers Disord 2012 Dec;26(6):919-26. doi: 10.1521/pedi.2012.26.6.919. PMID: 23281676
Kelley C
Narrat Inq Bioeth 2011 Spring;1(1):13-5. doi: 10.1353/nib.2011.0028. PMID: 24406521
Harrow M, Grinker RR, Holzman PS, Kayton L
Am J Psychiatry 1977 Jul;134(7):794-7. doi: 10.1176/ajp.134.7.794. PMID: 869058
Hanson DR, Gottesman II
J Autism Child Schizophr 1976 Sep;6(3):209-34. doi: 10.1007/BF01543463. PMID: 791920

Diagnosis

Arciniegas DB
Continuum (Minneap Minn) 2015 Jun;21(3 Behavioral Neurology and Neuropsychiatry):715-36. doi: 10.1212/01.CON.0000466662.89908.e7. PMID: 26039850Free PMC Article
Triebwasser J, Chemerinski E, Roussos P, Siever LJ
J Pers Disord 2012 Dec;26(6):919-26. doi: 10.1521/pedi.2012.26.6.919. PMID: 23281676
Kelley C
Narrat Inq Bioeth 2011 Spring;1(1):13-5. doi: 10.1353/nib.2011.0028. PMID: 24406521
Jones GS
Prostaglandins Leukot Essent Fatty Acids 2000 Jul-Aug;63(1-2):33-6. doi: 10.1054/plef.2000.0188. PMID: 10970710
Harrow M, Grinker RR, Holzman PS, Kayton L
Am J Psychiatry 1977 Jul;134(7):794-7. doi: 10.1176/ajp.134.7.794. PMID: 869058

Therapy

Arciniegas DB
Continuum (Minneap Minn) 2015 Jun;21(3 Behavioral Neurology and Neuropsychiatry):715-36. doi: 10.1212/01.CON.0000466662.89908.e7. PMID: 26039850Free PMC Article
Kelley C
Narrat Inq Bioeth 2011 Spring;1(1):13-5. doi: 10.1353/nib.2011.0028. PMID: 24406521
Farley-Loftus R, Elmariah SB, Ralston J, Kamino H, Franks AG Jr
Dermatol Online J 2010 Nov 15;16(11):1. PMID: 21163152
Kwapil TR
J Abnorm Psychol 1998 Nov;107(4):558-65. doi: 10.1037//0021-843x.107.4.558. PMID: 9830243
Kaplan HI, Sadock BJ
Can Psychiatr Assoc J 1971 Dec;16(6):457-71. doi: 10.1177/070674377101600602. PMID: 4947170

Prognosis

Long J, Hull R
Philos Ethics Humanit Med 2023 Nov 8;18(1):14. doi: 10.1186/s13010-023-00142-8. PMID: 37936219Free PMC Article
Kelley C
Narrat Inq Bioeth 2011 Spring;1(1):13-5. doi: 10.1353/nib.2011.0028. PMID: 24406521
Cantwell DP, Sturzenberger S, Burroughs J, Salkin B, Green JK
Arch Gen Psychiatry 1977 Sep;34(9):1087-93. doi: 10.1001/archpsyc.1977.01770210101009. PMID: 901137
Tsuang MT
Biol Psychiatry 1975 Aug;10(4):465-74. PMID: 1100126
Mellsop G
Aust N Z J Psychiatry 1973 Sep;7(3):208-11. doi: 10.3109/00048677309159750. PMID: 4588830

Clinical prediction guides

Martin EA, Cicero DC, Kerns JG
Personal Disord 2012 Jul;3(3):263-272. Epub 2011 Jul 4 doi: 10.1037/a0024488. PMID: 22452767
Farley-Loftus R, Elmariah SB, Ralston J, Kamino H, Franks AG Jr
Dermatol Online J 2010 Nov 15;16(11):1. PMID: 21163152
Parnas J, Jorgensen A
Br J Psychiatry 1989 Nov;155:623-7. doi: 10.1192/s0007125000018109. PMID: 2611591
Harrow M, Grinker RR, Holzman PS, Kayton L
Am J Psychiatry 1977 Jul;134(7):794-7. doi: 10.1176/ajp.134.7.794. PMID: 869058
Mnukhin SS, Isaev DN
J Autism Child Schizophr 1975 Jun;5(2):99-108. doi: 10.1007/BF01537927. PMID: 1174123

Recent systematic reviews

Ayerbe L, Forgnone I, Foguet-Boreu Q, González E, Addo J, Ayis S
Psychol Med 2018 Dec;48(16):2693-2701. Epub 2018 Mar 1 doi: 10.1017/S0033291718000302. PMID: 29490716

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