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Spinal Neoplasm

MedGen UID:
21281
•Concept ID:
C0037939
•
Neoplastic Process
Synonyms: Neoplasm, Spinal; Neoplasms, Spinal; Spinal Neoplasms
SNOMED CT: Neoplasm of vertebra (709289008)

Definition

A benign or malignant neoplasm that affects the vertebrae, vertebral canal, and/or spinal cord. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSpinal Neoplasm

Professional guidelines

PubMed

Disparities in reportable quality metrics by insurance status in the primary spine neoplasm population.
Mehdi SK, Tanenbaum JE, Alentado VJ, Miller JA, Lubelski D, Benzel EC, Mroz TE
Spine J 2017 Feb;17(2):244-251. Epub 2016 Sep 21 doi: 10.1016/j.spinee.2016.09.010. PMID: 27664341Free PMC Article
Role of MR imaging in the management of spinal infections.
Sharif HS
AJR Am J Roentgenol 1992 Jun;158(6):1333-45. doi: 10.2214/ajr.158.6.1590137. PMID: 1590137

Recent clinical studies

Etiology

Osteoporotic Vertebral Fracture Misdiagnosed as Metastatic Vertebral Fracture.
Yu T, Zheng S, Cheng X, Zhao J
J Coll Physicians Surg Pak 2022 Dec;32(12):SS171-SS173. doi: 10.29271/jcpsp.2022.Supp0.SS171. PMID: 36597329
Lumbopelvic shortening and local host bone-to-host bone reconstruction: a surgical method for lumbopelvic fusion following total sacrectomy.
Cherry A, Oitment C, Wunder J, Ferguson P, Rampersaud R
Eur Spine J 2022 Dec;31(12):3759-3767. Epub 2022 Sep 3 doi: 10.1007/s00586-022-07363-z. PMID: 36056967
Assessing long-term locoregional control of spinal osseous metastases after microwave ablation.
Motaghi M, England RW, Nejad NH, Sankaran N, Patel AM, Khan MA
J Clin Neurosci 2022 Oct;104:48-55. Epub 2022 Aug 11 doi: 10.1016/j.jocn.2022.07.025. PMID: 35963064
Elective laminectomy and excision of the thoracic spine neoplasm: an evaluation of early outcomes.
Upadhyayula PS, Yue JK, Curtis EI, Ciacci JD
J Neurosurg Sci 2019 Feb;63(1):1-10. Epub 2016 Nov 23 doi: 10.23736/S0390-5616.16.03868-6. PMID: 27879953
Spinal infections: clinical and imaging features.
Arbelaez A, Restrepo F, Castillo M
Top Magn Reson Imaging 2014 Oct;23(5):303-14. doi: 10.1097/RMR.0000000000000032. PMID: 25296275

Diagnosis

Osteoporotic Vertebral Fracture Misdiagnosed as Metastatic Vertebral Fracture.
Yu T, Zheng S, Cheng X, Zhao J
J Coll Physicians Surg Pak 2022 Dec;32(12):SS171-SS173. doi: 10.29271/jcpsp.2022.Supp0.SS171. PMID: 36597329
Spinal infections: clinical and imaging features.
Arbelaez A, Restrepo F, Castillo M
Top Magn Reson Imaging 2014 Oct;23(5):303-14. doi: 10.1097/RMR.0000000000000032. PMID: 25296275
Isolated central canal rupture of spinal dermoid. Report of 3 cases.
Garg K, Kumar R
J Neurosurg Spine 2014 Sep;21(3):361-6. Epub 2014 Jun 13 doi: 10.3171/2014.5.SPINE13900. PMID: 24926936
Schwannoma of the conus medullaris: a rare case.
Canbay S, Hasturk AE, Markoc F, Caglar S
Chin J Cancer 2011 Dec;30(12):867-70. Epub 2011 Nov 15 doi: 10.5732/cjc.011.10213. PMID: 22085527Free PMC Article
Spinal dermoid cysts originating intracranial fat drops causing obstructive hydrocephalus: case reports.
Cavazzani P, Ruelle A, Michelozzi G, Andrioli G
Surg Neurol 1995 May;43(5):466-9; discussion 469-70. doi: 10.1016/0090-3019(95)80091-t. PMID: 7660285

Therapy

Esketamine combined with pregabalin on acute postoperative pain in patients undergoing resection of spinal neoplasms: study protocol for a randomized controlled trial.
Sun W, Wang J, Wang J, Fan J, Zhou Y, Wang Y, Han R
Trials 2023 Feb 25;24(1):144. doi: 10.1186/s13063-023-07178-3. PMID: 36841794Free PMC Article
Assessing long-term locoregional control of spinal osseous metastases after microwave ablation.
Motaghi M, England RW, Nejad NH, Sankaran N, Patel AM, Khan MA
J Clin Neurosci 2022 Oct;104:48-55. Epub 2022 Aug 11 doi: 10.1016/j.jocn.2022.07.025. PMID: 35963064
Solitary vertebral metastatic glioblastoma in the absence of primary brain tumor relapse: a case report and literature review.
Li ZG, Zheng MY, Zhao Q, Liu K, Du JX, Zhang SW
BMC Med Imaging 2020 Jul 31;20(1):89. doi: 10.1186/s12880-020-00488-x. PMID: 32736607Free PMC Article
The Spinal Instability Neoplastic Score: Impact on Oncologic Decision-Making.
Versteeg AL, Verlaan JJ, Sahgal A, Mendel E, Quraishi NA, Fourney DR, Fisher CG
Spine (Phila Pa 1976) 2016 Oct 15;41 Suppl 20:S231-S237. doi: 10.1097/BRS.0000000000001822. PMID: 27488297
Fusion after intradural spine tumor resection in adults: A review of evidence and practices.
Avila MJ, Walter CM, Skoch J, Abbasifard S, Patel AS, Sattarov K, Baaj AA
Clin Neurol Neurosurg 2015 Nov;138:169-73. Epub 2015 Aug 28 doi: 10.1016/j.clineuro.2015.08.020. PMID: 26355808

Prognosis

DEVELOPMENT OF A MATHEMATICAL MODEL OF SELECTING THE EXTENT OF A SURGICAL INTERVENTION IN SPINAL TUMOR.
Popov A, Petrenko D, Kutsenko V, Lazarenko I, Bondarenko S, Popsuyshapka K, Maltseva V
Wiad Lek 2023;76(7):1627-1635. doi: 10.36740/WLek202307117. PMID: 37622507
An institutional review of 10 cases of spinal hemangiopericytoma/solitary fibrous tumor.
Singla R, Singh PK, Khanna G, Suri V, Agarwal D, Chandra PS, Kale SS, Mahapatra AK
Neurol India 2020 Mar-Apr;68(2):448-453. doi: 10.4103/0028-3886.284374. PMID: 32415022
Elective laminectomy and excision of the thoracic spine neoplasm: an evaluation of early outcomes.
Upadhyayula PS, Yue JK, Curtis EI, Ciacci JD
J Neurosurg Sci 2019 Feb;63(1):1-10. Epub 2016 Nov 23 doi: 10.23736/S0390-5616.16.03868-6. PMID: 27879953
Leptomeningeal dissemination of a low-grade lumbar paraganglioma: case report.
Thomson N, Pacak K, Schmidt MH, Palmer CA, Salzman KL, Champine M, Schiffman JD, Cohen AL
J Neurosurg Spine 2017 Apr;26(4):501-506. Epub 2017 Jan 27 doi: 10.3171/2016.10.SPINE16948. PMID: 28128698Free PMC Article
The Spinal Instability Neoplastic Score: Impact on Oncologic Decision-Making.
Versteeg AL, Verlaan JJ, Sahgal A, Mendel E, Quraishi NA, Fourney DR, Fisher CG
Spine (Phila Pa 1976) 2016 Oct 15;41 Suppl 20:S231-S237. doi: 10.1097/BRS.0000000000001822. PMID: 27488297

Clinical prediction guides

Esketamine combined with pregabalin on acute postoperative pain in patients undergoing resection of spinal neoplasms: study protocol for a randomized controlled trial.
Sun W, Wang J, Wang J, Fan J, Zhou Y, Wang Y, Han R
Trials 2023 Feb 25;24(1):144. doi: 10.1186/s13063-023-07178-3. PMID: 36841794Free PMC Article
Assessing long-term locoregional control of spinal osseous metastases after microwave ablation.
Motaghi M, England RW, Nejad NH, Sankaran N, Patel AM, Khan MA
J Clin Neurosci 2022 Oct;104:48-55. Epub 2022 Aug 11 doi: 10.1016/j.jocn.2022.07.025. PMID: 35963064
The role of 5-aminolevulinic acid in spinal tumor surgery: a review.
Wainwright JV, Endo T, Cooper JB, Tominaga T, Schmidt MH
J Neurooncol 2019 Feb;141(3):575-584. Epub 2018 Dec 29 doi: 10.1007/s11060-018-03080-0. PMID: 30594965Free PMC Article
Elective laminectomy and excision of the thoracic spine neoplasm: an evaluation of early outcomes.
Upadhyayula PS, Yue JK, Curtis EI, Ciacci JD
J Neurosurg Sci 2019 Feb;63(1):1-10. Epub 2016 Nov 23 doi: 10.23736/S0390-5616.16.03868-6. PMID: 27879953
The Spinal Instability Neoplastic Score: Impact on Oncologic Decision-Making.
Versteeg AL, Verlaan JJ, Sahgal A, Mendel E, Quraishi NA, Fourney DR, Fisher CG
Spine (Phila Pa 1976) 2016 Oct 15;41 Suppl 20:S231-S237. doi: 10.1097/BRS.0000000000001822. PMID: 27488297

Recent systematic reviews

Subaxial cervical foraminal chondromas: case-based discussion on surgical management.
Vandenbulcke A, Sanjurjo A, Rougemont AL, Boudabbous S, Maduri R
Neurosurg Rev 2024 Nov 4;47(1):834. doi: 10.1007/s10143-024-03065-w. PMID: 39489866Free PMC Article
Fluorescence-guided resection of intradural spinal tumors: a systematic review and meta-analysis.
Albalkhi I, Shafqat A, Bin-Alamer O, Abou Al-Shaar AR, Mallela AN, Fernández-de Thomas RJ, Zinn PO, Gerszten PC, Hadjipanayis CG, Abou-Al-Shaar H
Neurosurg Rev 2023 Dec 12;47(1):10. doi: 10.1007/s10143-023-02230-x. PMID: 38085385
Spinal Myxopapillary Ependymoma: The Sapienza University Experience and Comprehensive Literature Review Concerning the Clinical Course of 1602 Patients.
Pesce A, Palmieri M, Armocida D, Frati A, Miscusi M, Raco A
World Neurosurg 2019 Sep;129:245-253. Epub 2019 May 29 doi: 10.1016/j.wneu.2019.05.206. PMID: 31152881
The Spinal Instability Neoplastic Score: Impact on Oncologic Decision-Making.
Versteeg AL, Verlaan JJ, Sahgal A, Mendel E, Quraishi NA, Fourney DR, Fisher CG
Spine (Phila Pa 1976) 2016 Oct 15;41 Suppl 20:S231-S237. doi: 10.1097/BRS.0000000000001822. PMID: 27488297
Primary diffuse-type tenosynovial giant cell tumor of the spine: a report of 3 cases and systemic review of the literature.
Wang K, Zhu B, Yang S, Liu Z, Yu M, Liu X
Turk Neurosurg 2014;24(5):804-13. doi: 10.5137/1019-5149.JTN.9594-13.1. PMID: 25269059

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