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Adult central nervous system mature teratoma

MedGen UID:
231037
•Concept ID:
C1332194
•
Neoplastic Process
Synonyms: Adult Central Nervous System Mature Teratoma; adult central nervous system mature teratoma; central nervous system mature teratoma of adults
 
Monarch Initiative: MONDO:0003732

Definition

A mature teratoma that arises from the central nervous system in adults. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult central nervous system mature teratoma

Professional guidelines

PubMed

Central nervous system germ cell tumors: classification, clinical features, and treatment with a historical overview.
Fujimaki T
J Child Neurol 2009 Nov;24(11):1439-45. doi: 10.1177/0883073809342127. PMID: 19841431
Teratomas of the central nervous system: treatment considerations based on 34 cases.
Sawamura Y, Kato T, Ikeda J, Murata J, Tada M, Shirato H
J Neurosurg 1998 Nov;89(5):728-37. doi: 10.3171/jns.1998.89.5.0728. PMID: 9817409
Carcinoma of the thyroid with leptomeningeal dissemination following the treatment of a toxic goitre with 131-I and methyl thiouracil. Case with a co-existing intracranial dermoid.
Barnard RO, Parsons M
J Neurol Sci 1969 Mar-Apr;8(2):299-306. doi: 10.1016/0022-510x(69)90114-2. PMID: 5805759

Recent clinical studies

Etiology

Pineal/germ cell tumors and pineal parenchymal tumors.
Ogiwara H, Liao YM, Wong TT
Childs Nerv Syst 2023 Oct;39(10):2649-2665. Epub 2023 Oct 13 doi: 10.1007/s00381-023-06081-1. PMID: 37831207
Brain and Spinal Tumors Originating from the Germ Line Cells.
Wong TT, Tsai ML, Chang H, Hsieh KL, Ho DM, Lin SC, Yen HJ, Chen YW, Lee HL, Yang TF
Adv Exp Med Biol 2023;1405:421-455. doi: 10.1007/978-3-031-23705-8_16. PMID: 37452948
Spinal Dermoid Cyst with Spontaneous Rupture into the Syrinx Cavity Alone.
Liu T, Deng X, Xu Y, Xin Y
World Neurosurg 2018 Oct;118:e395-e404. Epub 2018 Jul 3 doi: 10.1016/j.wneu.2018.06.201. PMID: 30257295
Teratomas in central nervous system: a clinico-morphological study with review of literature.
Agrawal M, Uppin MS, Patibandla MR, Bhattacharjee S, Panigrahi MK, Saradhi V, Rani JY, Purohit AK, Challa S
Neurol India 2010 Nov-Dec;58(6):841-6. doi: 10.4103/0028-3886.73740. PMID: 21150046
Split-cord malformation and accompanying anomalies.
Ozturk E, Sonmez G, Mutlu H, Sildiroglu HO, Velioglu M, Basekim CC, Kizilkaya E
J Neuroradiol 2008 Jul;35(3):150-6. Epub 2008 Feb 21 doi: 10.1016/j.neurad.2007.11.006. PMID: 18206241

Diagnosis

Pineal/germ cell tumors and pineal parenchymal tumors.
Ogiwara H, Liao YM, Wong TT
Childs Nerv Syst 2023 Oct;39(10):2649-2665. Epub 2023 Oct 13 doi: 10.1007/s00381-023-06081-1. PMID: 37831207
A Hairbrained Mature Cystic Ovarian Teratoma: With Bone Marrow, Meninges, and Intraglial Hair.
Pai SA
Int J Surg Pathol 2021 Jun;29(4):404-405. Epub 2020 Jun 3 doi: 10.1177/1066896920927460. PMID: 32489128
Low-grade developmental and epilepsy associated brain tumors: a critical update 2020.
Slegers RJ, Blumcke I
Acta Neuropathol Commun 2020 Mar 9;8(1):27. doi: 10.1186/s40478-020-00904-x. PMID: 32151273Free PMC Article
Rare Case of Giant Supratentorial Dermoid Cyst.
Obled L, Peciu-Florianu I, Perbet R, Vannod-Michel Q, Reyns N
World Neurosurg 2020 Mar;135:72-75. Epub 2019 Dec 9 doi: 10.1016/j.wneu.2019.12.007. PMID: 31821914
Split-cord malformation and accompanying anomalies.
Ozturk E, Sonmez G, Mutlu H, Sildiroglu HO, Velioglu M, Basekim CC, Kizilkaya E
J Neuroradiol 2008 Jul;35(3):150-6. Epub 2008 Feb 21 doi: 10.1016/j.neurad.2007.11.006. PMID: 18206241

Therapy

Subarachnoid fat dissemination secondary to intrathecal pump.
Riestenberg RA, Omofoye OA, Lee D, Shahlaie K
J Clin Neurosci 2020 Aug;78:416-417. Epub 2020 Apr 30 doi: 10.1016/j.jocn.2020.04.120. PMID: 32362469
Teaching NeuroImages: Greater occipital nerve injection: A cautionary tale.
Wei DY, Connor S, Goadsby PJ
Neurology 2019 Feb 12;92(7):e746-e747. doi: 10.1212/WNL.0000000000006929. PMID: 30745452
Cerebellar mutism in adults after posterior fossa surgery: a report of 2 cases.
Sherman JH, Sheehan JP, Elias WJ, Jane JA Sr
Surg Neurol 2005 May;63(5):476-9. doi: 10.1016/j.surneu.2004.06.015. PMID: 15883080
Metrizamide in pediatric myelography.
Barry JF, Harwood-Nash DC, Fitz CR, Byrd SE, Boldt DW
Radiology 1977 Aug;124(2):409-18. doi: 10.1148/124.2.409. PMID: 877281
Epidermoid and dermoid sequestration cysts.
Pear BL
Am J Roentgenol Radium Ther Nucl Med 1970 Sep;110(1):148-55. doi: 10.2214/ajr.110.1.148. PMID: 5469090

Prognosis

Brain and Spinal Tumors Originating from the Germ Line Cells.
Wong TT, Tsai ML, Chang H, Hsieh KL, Ho DM, Lin SC, Yen HJ, Chen YW, Lee HL, Yang TF
Adv Exp Med Biol 2023;1405:421-455. doi: 10.1007/978-3-031-23705-8_16. PMID: 37452948
Spinal Dermoid Cyst with Spontaneous Rupture into the Syrinx Cavity Alone.
Liu T, Deng X, Xu Y, Xin Y
World Neurosurg 2018 Oct;118:e395-e404. Epub 2018 Jul 3 doi: 10.1016/j.wneu.2018.06.201. PMID: 30257295
Teratomas in central nervous system: a clinico-morphological study with review of literature.
Agrawal M, Uppin MS, Patibandla MR, Bhattacharjee S, Panigrahi MK, Saradhi V, Rani JY, Purohit AK, Challa S
Neurol India 2010 Nov-Dec;58(6):841-6. doi: 10.4103/0028-3886.73740. PMID: 21150046
Sylvian cistern dermoid cyst presenting with dysgeusia.
Kocaeli H, Korfali E, Doğan S, Savran M
Acta Neurochir (Wien) 2009 May;151(5):561-3. Epub 2009 Mar 17 doi: 10.1007/s00701-009-0261-1. PMID: 19290464
Split-cord malformation and accompanying anomalies.
Ozturk E, Sonmez G, Mutlu H, Sildiroglu HO, Velioglu M, Basekim CC, Kizilkaya E
J Neuroradiol 2008 Jul;35(3):150-6. Epub 2008 Feb 21 doi: 10.1016/j.neurad.2007.11.006. PMID: 18206241

Clinical prediction guides

Subarachnoid fat dissemination secondary to intrathecal pump.
Riestenberg RA, Omofoye OA, Lee D, Shahlaie K
J Clin Neurosci 2020 Aug;78:416-417. Epub 2020 Apr 30 doi: 10.1016/j.jocn.2020.04.120. PMID: 32362469
Primary and Recurrent Growing Teratoma Syndrome in Central Nervous System Nongerminomatous Germ Cell Tumors: Case Series and Review of the Literature.
Tsuyuguchi S, Sugiyama K, Kinoshita Y, Kolakshyapati M, Takayasu T, Usui S, Takano M, Yonezawa U, Taguchi A, Amatya VJ, Takeshima Y, Kurisu K, Yamasaki F
World Neurosurg 2020 Feb;134:e360-e371. Epub 2019 Nov 18 doi: 10.1016/j.wneu.2019.10.074. PMID: 31751614
A spinal dermoid cyst with spontaneous rupture into the syrinx cavity: a case report.
Ozsoy KM, Okten AI, Arslan A, Guzel E, Guzel A, Cennet A
Turk Neurosurg 2014;24(2):256-8. doi: 10.5137/1019-5149.JTN.5886-12.2. PMID: 24831371
Development of functional human embryonic stem cell-derived neurons in mouse brain.
Muotri AR, Nakashima K, Toni N, Sandler VM, Gage FH
Proc Natl Acad Sci U S A 2005 Dec 20;102(51):18644-8. Epub 2005 Dec 13 doi: 10.1073/pnas.0509315102. PMID: 16352714Free PMC Article
Benign cysts in the central nervous system: neuropathological observations of the cyst walls.
Hirano A, Hirano M
Neuropathology 2004 Mar;24(1):1-7. doi: 10.1111/j.1440-1789.2003.00526.x. PMID: 15068166

Recent systematic reviews

Suprasellar Mature Cystic Teratoma Mimicking Rathke's Cleft Cyst: A Case Report and Systematic Review of the Literature.
Jiang S, Wang Z, You Y, Wang R, Bao X
Front Endocrinol (Lausanne) 2021;12:731088. Epub 2021 Sep 30 doi: 10.3389/fendo.2021.731088. PMID: 34659119Free PMC Article

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