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Adult central nervous system mixed germ cell tumor

MedGen UID:
231038
Concept ID:
C1332195
Neoplastic Process
Synonyms: Adult Central Nervous System Mixed Germ Cell Tumor; adult central nervous system mixed germ cell tumor; adult mixed germ cell tumor of central nervous system; adult mixed germ cell tumour of central nervous system; mixed germ cell tumor of central nervous system of adults; mixed germ cell tumour of central nervous system of adults
 
Monarch Initiative: MONDO:0004406

Definition

A mixed germ cell tumor of central nervous system that occurs in an adult. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult central nervous system mixed germ cell tumor

Professional guidelines

PubMed

Demir MK, Yapıcıer O, Kılıc T, Celik S, Oven BB, Ozdamarlar U, Kundak NE, Kanan D, Dincer A, Ertem O, Yakut T, Yılmaz B, Safi S
Curr Med Imaging 2023;19(12):1415-1426. doi: 10.2174/1573405619666230213152949. PMID: 36788686
Yeo KK, Nagabushan S, Dhall G, Abdelbaki MS
Neoplasia 2023 Feb;36:100860. Epub 2022 Dec 13 doi: 10.1016/j.neo.2022.100860. PMID: 36521378Free PMC Article
Fouke SJ, Benzinger T, Gibson D, Ryken TC, Kalkanis SN, Olson JJ
J Neurooncol 2015 Dec;125(3):457-79. Epub 2015 Nov 3 doi: 10.1007/s11060-015-1908-9. PMID: 26530262

Recent clinical studies

Etiology

Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Kundu P, Li MD, Durkee BY, Hiniker SM, Bush K, von Eyben R, Monje ML, Yeom KW, Donaldson SS, Gibbs IC
J Neurooncol 2017 Jun;133(2):429-434. Epub 2017 May 22 doi: 10.1007/s11060-017-2453-5. PMID: 28534154Free PMC Article
van den Bent MJ, Afra D, de Witte O, Ben Hassel M, Schraub S, Hoang-Xuan K, Malmström PO, Collette L, Piérart M, Mirimanoff R, Karim AB; EORTC Radiotherapy and Brain Tumor Groups and the UK Medical Research Council
Lancet 2005 Sep 17-23;366(9490):985-90. doi: 10.1016/S0140-6736(05)67070-5. PMID: 16168780
Burton EC, Prados MD
Curr Treat Options Oncol 2000 Dec;1(5):459-68. doi: 10.1007/s11864-000-0073-2. PMID: 12057153
Hart MN, Petito CK, Earle KM
Cancer 1974 Jan;33(1):134-40. doi: 10.1002/1097-0142(197401)33:1<134::aid-cncr2820330120>3.0.co;2-i. PMID: 4810087

Diagnosis

Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Viaene AN, Santi M, Hawkins C
Pediatr Dev Pathol 2022 Jan-Feb;25(1):46-58. Epub 2021 Apr 19 doi: 10.1177/10935266211009101. PMID: 33872106
Abdel Razek AAK, Elsebaie NA, Zamora C, Castillo M
J Comput Assist Tomogr 2020 May/Jun;44(3):356-369. doi: 10.1097/RCT.0000000000001010. PMID: 32217897
Slegers RJ, Blumcke I
Acta Neuropathol Commun 2020 Mar 9;8(1):27. doi: 10.1186/s40478-020-00904-x. PMID: 32151273Free PMC Article
Burton EC, Prados MD
Curr Treat Options Oncol 2000 Dec;1(5):459-68. doi: 10.1007/s11864-000-0073-2. PMID: 12057153

Therapy

Kundu P, Li MD, Durkee BY, Hiniker SM, Bush K, von Eyben R, Monje ML, Yeom KW, Donaldson SS, Gibbs IC
J Neurooncol 2017 Jun;133(2):429-434. Epub 2017 May 22 doi: 10.1007/s11060-017-2453-5. PMID: 28534154Free PMC Article
Krieger MD, McComb JG
Childs Nerv Syst 2009 Oct;25(10):1269-73. Epub 2009 Apr 9 doi: 10.1007/s00381-009-0879-6. PMID: 19357854
Lang FF, Gilbert MR
J Clin Oncol 2006 Mar 10;24(8):1236-45. doi: 10.1200/JCO.2005.05.2399. PMID: 16525178
van den Bent MJ, Afra D, de Witte O, Ben Hassel M, Schraub S, Hoang-Xuan K, Malmström PO, Collette L, Piérart M, Mirimanoff R, Karim AB; EORTC Radiotherapy and Brain Tumor Groups and the UK Medical Research Council
Lancet 2005 Sep 17-23;366(9490):985-90. doi: 10.1016/S0140-6736(05)67070-5. PMID: 16168780
Burton EC, Prados MD
Curr Treat Options Oncol 2000 Dec;1(5):459-68. doi: 10.1007/s11864-000-0073-2. PMID: 12057153

Prognosis

Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Viaene AN, Santi M, Hawkins C
Pediatr Dev Pathol 2022 Jan-Feb;25(1):46-58. Epub 2021 Apr 19 doi: 10.1177/10935266211009101. PMID: 33872106
Langlois AM, Alarfaj AK, Sagga A, Findlay JM, Das S
Am J Case Rep 2019 Jun 27;20:914-919. doi: 10.12659/AJCR.916020. PMID: 31243260Free PMC Article
Lang FF, Gilbert MR
J Clin Oncol 2006 Mar 10;24(8):1236-45. doi: 10.1200/JCO.2005.05.2399. PMID: 16525178
Hart MN, Petito CK, Earle KM
Cancer 1974 Jan;33(1):134-40. doi: 10.1002/1097-0142(197401)33:1<134::aid-cncr2820330120>3.0.co;2-i. PMID: 4810087

Clinical prediction guides

Lampros MG, Vlachos N, Voulgaris S, Alexiou GA
Childs Nerv Syst 2021 Aug;37(8):2465-2474. Epub 2021 Jun 17 doi: 10.1007/s00381-021-05257-x. PMID: 34137942
Ding X, Sun J, Fan T, Li B
Medicine (Baltimore) 2018 Jun;97(22):e10859. doi: 10.1097/MD.0000000000010859. PMID: 29851800Free PMC Article
Kundu P, Li MD, Durkee BY, Hiniker SM, Bush K, von Eyben R, Monje ML, Yeom KW, Donaldson SS, Gibbs IC
J Neurooncol 2017 Jun;133(2):429-434. Epub 2017 May 22 doi: 10.1007/s11060-017-2453-5. PMID: 28534154Free PMC Article
Yu X, Liu R, Wang Y, Wang H, Zhao H, Wu Z
Clin Neurol Neurosurg 2012 Feb;114(2):112-9. Epub 2011 Oct 21 doi: 10.1016/j.clineuro.2011.09.010. PMID: 22018920
Englot DJ, Berger MS, Barbaro NM, Chang EF
J Neurosurg 2011 Aug;115(2):240-4. Epub 2011 Apr 29 doi: 10.3171/2011.3.JNS1153. PMID: 21529134

Recent systematic reviews

Pascual JSG, Khu KJO, Starreveld YP
Neuropsychologia 2023 Jan 28;179:108450. Epub 2022 Dec 16 doi: 10.1016/j.neuropsychologia.2022.108450. PMID: 36529263
Lampros MG, Vlachos N, Voulgaris S, Alexiou GA
Childs Nerv Syst 2021 Aug;37(8):2465-2474. Epub 2021 Jun 17 doi: 10.1007/s00381-021-05257-x. PMID: 34137942
Graffeo CS, Perry A, Copeland WR 3rd, Giannini C, Neff BA, Driscoll CL, Link MJ
World Neurosurg 2017 Feb;98:632-643. Epub 2016 Nov 12 doi: 10.1016/j.wneu.2016.11.002. PMID: 27836701
Fouke SJ, Benzinger T, Gibson D, Ryken TC, Kalkanis SN, Olson JJ
J Neurooncol 2015 Dec;125(3):457-79. Epub 2015 Nov 3 doi: 10.1007/s11060-015-1908-9. PMID: 26530262
Englot DJ, Berger MS, Barbaro NM, Chang EF
J Neurosurg 2011 Aug;115(2):240-4. Epub 2011 Apr 29 doi: 10.3171/2011.3.JNS1153. PMID: 21529134

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