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Adrenal gland ganglioneuroblastoma

MedGen UID:
231355
•Concept ID:
C1332176
•
Neoplastic Process
Synonyms: Adrenal Ganglioneuroblastoma; adrenal ganglioneuroblastoma; Adrenal Gland Ganglioneuroblastoma; adrenal gland ganglioneuroblastoma; adrenal gland ganglioneuroblastoma (disease); ganglioneuroblastoma (disease) of adrenal gland
 
Monarch Initiative: MONDO:0004477

Definition

A ganglioneuroblastoma arising from the adrenal gland. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdrenal gland ganglioneuroblastoma

Professional guidelines

PubMed

Clinical features and treatment options for pediatric adrenal incidentalomas: a retrospective single center study.
Zhu X, Liu S, Yuan Y, Gu N, Sha J, Guo Y, Deng Y
BMC Pediatr 2024 Mar 16;24(1):186. doi: 10.1186/s12887-024-04673-7. PMID: 38491421Free PMC Article
Early Detection and Treatment of Neuroblastic Tumor with Opsoclonus-Myoclonus Syndrome Improve Neurological Outcome: A Review of Five Cases at a Single Institution in Japan.
Takama Y, Yoneda A, Nakamura T, Nakaoka T, Higashio A, Santo K, Kuki I, Kawawaki H, Tomiwa K, Hara J
Eur J Pediatr Surg 2016 Feb;26(1):54-9. Epub 2015 Sep 26 doi: 10.1055/s-0035-1564714. PMID: 26409265
DNA-topoisomerase I, a new target for the treatment of neuroblastoma.
Vassal G, Pondarré C, Cappelli C, Terrier-Lacombe MJ, Boland I, Morizet J, Bénard J, Vénuat AM, Ardouin P, Hartmann O, Gouyette A
Eur J Cancer 1997 Oct;33(12):2011-5. doi: 10.1016/s0959-8049(97)00296-7. PMID: 9516844

Recent clinical studies

Etiology

Incidence of Horner syndrome associated with neuroblastic disease.
Kuchalska K, Barełkowska M, Derwich K, Jończyk-Potoczna K, Gotz-Więckowska A
Childs Nerv Syst 2021 Apr;37(4):1243-1247. Epub 2020 Nov 10 doi: 10.1007/s00381-020-04966-z. PMID: 33174155Free PMC Article
ROHHAD(NET) Syndrome: Systematic Review of the Clinical Timeline and Recommendations for Diagnosis and Prognosis.
Harvengt J, Gernay C, Mastouri M, Farhat N, Lebrethon MC, Seghaye MC, Bours V
J Clin Endocrinol Metab 2020 Jul 1;105(7) doi: 10.1210/clinem/dgaa247. PMID: 32407531
Prolonged Isotretinoin in Ultra High-Risk Neuroblastoma.
Cash T, Alazraki A, Qayed M, Katzenstein HM
J Pediatr Hematol Oncol 2017 Jan;39(1):e33-e35. doi: 10.1097/MPH.0000000000000695. PMID: 27820130
Two cases of neuroblastoma comprising two distinct clones.
Yamazaki F, Nakazawa A, Osumi T, Shimojima N, Tanaka T, Nakagawara A, Shimada H
Pediatr Blood Cancer 2014 Apr;61(4):760-2. Epub 2013 Sep 20 doi: 10.1002/pbc.24779. PMID: 24108545
Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: radiologic-pathologic correlation.
Lonergan GJ, Schwab CM, Suarez ES, Carlson CL
Radiographics 2002 Jul-Aug;22(4):911-34. doi: 10.1148/radiographics.22.4.g02jl15911. PMID: 12110723

Diagnosis

Benign Neurogenic Tumors.
Farma JM, Porpiglia AS, Vo ET
Surg Clin North Am 2022 Aug;102(4):679-693. doi: 10.1016/j.suc.2022.04.007. PMID: 35952696
A Metastatic Neuroblastic Tumor in a 28-Month-old Boy: Unusual Spontaneous Regression From Neuroblastoma to Ganglioneuroma?
Yamada A, Kinoshita M, Kamimura S, Nakame K, Moritake H
J Pediatr Hematol Oncol 2022 Mar 1;44(2):e589-e592. doi: 10.1097/MPH.0000000000002226. PMID: 34054050
Incidence of Horner syndrome associated with neuroblastic disease.
Kuchalska K, Barełkowska M, Derwich K, Jończyk-Potoczna K, Gotz-Więckowska A
Childs Nerv Syst 2021 Apr;37(4):1243-1247. Epub 2020 Nov 10 doi: 10.1007/s00381-020-04966-z. PMID: 33174155Free PMC Article
ROHHAD(NET) Syndrome: Systematic Review of the Clinical Timeline and Recommendations for Diagnosis and Prognosis.
Harvengt J, Gernay C, Mastouri M, Farhat N, Lebrethon MC, Seghaye MC, Bours V
J Clin Endocrinol Metab 2020 Jul 1;105(7) doi: 10.1210/clinem/dgaa247. PMID: 32407531
Prenatally diagnosed cystic neuroblastoma.
Hamada Y, Ikebukuro K, Sato M, Tanano A, Kato Y, Takada K, Hioki K
Pediatr Surg Int 1999;15(1):71-4. doi: 10.1007/s003830050518. PMID: 9914363

Therapy

Diagnostic value of whole-body MRI in Opsoclonus-myoclonus syndrome: a clinical case series (3 case reports).
Storz C, Bares R, Ebinger M, Handgretinger R, Tsiflikas I, Schäfer JF
BMC Med Imaging 2019 Aug 20;19(1):70. doi: 10.1186/s12880-019-0372-y. PMID: 31429709Free PMC Article
Prolonged Isotretinoin in Ultra High-Risk Neuroblastoma.
Cash T, Alazraki A, Qayed M, Katzenstein HM
J Pediatr Hematol Oncol 2017 Jan;39(1):e33-e35. doi: 10.1097/MPH.0000000000000695. PMID: 27820130
Rituximab for treatment of opsoclonus-myoclonus syndrome in neuroblastoma.
Burke MJ, Cohn SL
Pediatr Blood Cancer 2008 Mar;50(3):679-80. doi: 10.1002/pbc.21009. PMID: 16900484
Ganglioneuroblastoma metastatic to the orbit.
Johnson TE, Toledano SR
Ophthalmic Plast Reconstr Surg 2003 Jul;19(4):330-3. doi: 10.1097/01.IOP.0000075051.57138.5E. PMID: 12878887
Adrenocortical adenoma and ganglioneuroblastoma in a child. A case presenting as Cushing syndrome with virilization.
Dahms WT, Gray G, Vrana M, New MI
Am J Dis Child 1973 Apr;125(4):608-11. doi: 10.1001/archpedi.1973.04160040102022. PMID: 4267005

Prognosis

Incidence of Horner syndrome associated with neuroblastic disease.
Kuchalska K, Barełkowska M, Derwich K, Jończyk-Potoczna K, Gotz-Więckowska A
Childs Nerv Syst 2021 Apr;37(4):1243-1247. Epub 2020 Nov 10 doi: 10.1007/s00381-020-04966-z. PMID: 33174155Free PMC Article
ROHHAD(NET) Syndrome: Systematic Review of the Clinical Timeline and Recommendations for Diagnosis and Prognosis.
Harvengt J, Gernay C, Mastouri M, Farhat N, Lebrethon MC, Seghaye MC, Bours V
J Clin Endocrinol Metab 2020 Jul 1;105(7) doi: 10.1210/clinem/dgaa247. PMID: 32407531
Prolonged Isotretinoin in Ultra High-Risk Neuroblastoma.
Cash T, Alazraki A, Qayed M, Katzenstein HM
J Pediatr Hematol Oncol 2017 Jan;39(1):e33-e35. doi: 10.1097/MPH.0000000000000695. PMID: 27820130
Two cases of neuroblastoma comprising two distinct clones.
Yamazaki F, Nakazawa A, Osumi T, Shimojima N, Tanaka T, Nakagawara A, Shimada H
Pediatr Blood Cancer 2014 Apr;61(4):760-2. Epub 2013 Sep 20 doi: 10.1002/pbc.24779. PMID: 24108545
Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: radiologic-pathologic correlation.
Lonergan GJ, Schwab CM, Suarez ES, Carlson CL
Radiographics 2002 Jul-Aug;22(4):911-34. doi: 10.1148/radiographics.22.4.g02jl15911. PMID: 12110723

Clinical prediction guides

Clinical features and treatment options for pediatric adrenal incidentalomas: a retrospective single center study.
Zhu X, Liu S, Yuan Y, Gu N, Sha J, Guo Y, Deng Y
BMC Pediatr 2024 Mar 16;24(1):186. doi: 10.1186/s12887-024-04673-7. PMID: 38491421Free PMC Article
Update on Adrenal Tumours in 2017 World Health Organization (WHO) of Endocrine Tumours.
Lam AK
Endocr Pathol 2017 Sep;28(3):213-227. doi: 10.1007/s12022-017-9484-5. PMID: 28477311
Long-term follow-up results of the observation program for neuroblastoma detected at 6-month mass screening.
Arakawa A, Oguma E, Aihara T, Kishimoto H, Kikuchi A, Hanada R, Koh K
J Pediatr 2014 Oct;165(4):855-7.e1. Epub 2014 Aug 3 doi: 10.1016/j.jpeds.2014.06.055. PMID: 25091258
The calcium-sensing receptor is silenced by genetic and epigenetic mechanisms in unfavorable neuroblastomas and its reactivation induces ERK1/2-dependent apoptosis.
Casalà C, Gil-Guiñón E, Ordóñez JL, Miguel-Queralt S, Rodríguez E, Galván P, Lavarino C, Munell F, de Alava E, Mora J, de Torres C
Carcinogenesis 2013 Feb;34(2):268-76. Epub 2012 Oct 29 doi: 10.1093/carcin/bgs338. PMID: 23108190
N-myc gene product expression in neuroblastoma.
Hashimoto H, Daimaru Y, Enjoji M, Nakagawara A
J Clin Pathol 1989 Jan;42(1):52-5. doi: 10.1136/jcp.42.1.52. PMID: 2921345Free PMC Article

Recent systematic reviews

Composite phaeochromocytomas-a systematic review of published literature.
Dhanasekar K, Visakan V, Tahir F, Balasubramanian SP
Langenbecks Arch Surg 2022 Mar;407(2):517-527. Epub 2021 Mar 2 doi: 10.1007/s00423-021-02129-5. PMID: 33651160Free PMC Article
ROHHAD(NET) Syndrome: Systematic Review of the Clinical Timeline and Recommendations for Diagnosis and Prognosis.
Harvengt J, Gernay C, Mastouri M, Farhat N, Lebrethon MC, Seghaye MC, Bours V
J Clin Endocrinol Metab 2020 Jul 1;105(7) doi: 10.1210/clinem/dgaa247. PMID: 32407531

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