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Invasive Cervical Carcinoma

MedGen UID:
233552
Concept ID:
C1334177
Neoplastic Process
Synonyms: Cancer of uterine cervix, invasive; Carcinoma of uterine cervix, invasive; Infiltrating Cervical Carcinoma; Invasive cervical cancer
SNOMED CT: Carcinoma of uterine cervix, invasive (423973006); Cancer of uterine cervix, invasive (423973006); Invasive cervical cancer (423973006)

Definition

A carcinoma that arises from the cervix and invades into the stromal tissue. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInvasive Cervical Carcinoma

Professional guidelines

PubMed

Tewari KS, Monk BJ
J Clin Oncol 2019 Sep 20;37(27):2472-2489. Epub 2019 Aug 12 doi: 10.1200/JCO.18.02303. PMID: 31403858Free PMC Article
Javadi S, Menias CO, Karbasian N, Shaaban A, Shah K, Osman A, Jensen CT, Lubner MG, Gaballah AH, Elsayes KM
Radiographics 2018 Nov-Dec;38(7):2051-2068. Epub 2018 Oct 19 doi: 10.1148/rg.2018180149. PMID: 30339518
Morice P, Narducci F, Mathevet P, Marret H, Darai E, Querleu D; French Working Group on Gynecological Cancers in Pregnancy; Société Française d'Oncologie Gynécologique (SFOG); Société Française de Chirurgie Pelvienne (SFCP); Collège National des Gynécologues Obstétriciens Français (CNGOF)
Int J Gynecol Cancer 2009 Dec;19(9):1638-41. doi: 10.1111/IGC.0b013e3181a83017. PMID: 19955951

Recent clinical studies

Etiology

Javadi S, Menias CO, Karbasian N, Shaaban A, Shah K, Osman A, Jensen CT, Lubner MG, Gaballah AH, Elsayes KM
Radiographics 2018 Nov-Dec;38(7):2051-2068. Epub 2018 Oct 19 doi: 10.1148/rg.2018180149. PMID: 30339518
Huh WK, Joura EA, Giuliano AR, Iversen OE, de Andrade RP, Ault KA, Bartholomew D, Cestero RM, Fedrizzi EN, Hirschberg AL, Mayrand MH, Ruiz-Sternberg AM, Stapleton JT, Wiley DJ, Ferenczy A, Kurman R, Ronnett BM, Stoler MH, Cuzick J, Garland SM, Kjaer SK, Bautista OM, Haupt R, Moeller E, Ritter M, Roberts CC, Shields C, Luxembourg A
Lancet 2017 Nov 11;390(10108):2143-2159. Epub 2017 Sep 5 doi: 10.1016/S0140-6736(17)31821-4. PMID: 28886907
Herrington CS
Cytopathology 2015 Dec;26(6):346-50. doi: 10.1111/cyt.12307. PMID: 26767601
Ronco G, Dillner J, Elfström KM, Tunesi S, Snijders PJ, Arbyn M, Kitchener H, Segnan N, Gilham C, Giorgi-Rossi P, Berkhof J, Peto J, Meijer CJ; International HPV screening working group
Lancet 2014 Feb 8;383(9916):524-32. Epub 2013 Nov 3 doi: 10.1016/S0140-6736(13)62218-7. PMID: 24192252
Bornstein J, Schwartz J, Perri A, Harroch J, Zarfati D
Obstet Gynecol Surv 2004 Sep;59(9):663-8. doi: 10.1097/01.ogx.0000137612.87012.66. PMID: 15329559

Diagnosis

Alldredge J, Leaf MC, Patel P, Coakley K, Longoria T, McLaren C, Randall LM
Int J Gynecol Cancer 2020 Jun;30(6):772-776. Epub 2020 Mar 9 doi: 10.1136/ijgc-2019-000909. PMID: 32156714Free PMC Article
Javadi S, Menias CO, Karbasian N, Shaaban A, Shah K, Osman A, Jensen CT, Lubner MG, Gaballah AH, Elsayes KM
Radiographics 2018 Nov-Dec;38(7):2051-2068. Epub 2018 Oct 19 doi: 10.1148/rg.2018180149. PMID: 30339518
Huh WK, Joura EA, Giuliano AR, Iversen OE, de Andrade RP, Ault KA, Bartholomew D, Cestero RM, Fedrizzi EN, Hirschberg AL, Mayrand MH, Ruiz-Sternberg AM, Stapleton JT, Wiley DJ, Ferenczy A, Kurman R, Ronnett BM, Stoler MH, Cuzick J, Garland SM, Kjaer SK, Bautista OM, Haupt R, Moeller E, Ritter M, Roberts CC, Shields C, Luxembourg A
Lancet 2017 Nov 11;390(10108):2143-2159. Epub 2017 Sep 5 doi: 10.1016/S0140-6736(17)31821-4. PMID: 28886907
American College of Obstetricians and Gynecologists.
Int J Gynaecol Obstet 2002 Jul;78(1):79-91. doi: 10.1016/s0020-7292(02)90092-5. PMID: 12197489
Hricak H, Lacey CG, Sandles LG, Chang YC, Winkler ML, Stern JL
Radiology 1988 Mar;166(3):623-31. doi: 10.1148/radiology.166.3.3340756. PMID: 3340756

Therapy

Barillari G, Monini P, Sgadari C, Ensoli B
Int J Mol Sci 2018 May 9;19(5) doi: 10.3390/ijms19051418. PMID: 29747434Free PMC Article
Huh WK, Joura EA, Giuliano AR, Iversen OE, de Andrade RP, Ault KA, Bartholomew D, Cestero RM, Fedrizzi EN, Hirschberg AL, Mayrand MH, Ruiz-Sternberg AM, Stapleton JT, Wiley DJ, Ferenczy A, Kurman R, Ronnett BM, Stoler MH, Cuzick J, Garland SM, Kjaer SK, Bautista OM, Haupt R, Moeller E, Ritter M, Roberts CC, Shields C, Luxembourg A
Lancet 2017 Nov 11;390(10108):2143-2159. Epub 2017 Sep 5 doi: 10.1016/S0140-6736(17)31821-4. PMID: 28886907
Ronco G, Dillner J, Elfström KM, Tunesi S, Snijders PJ, Arbyn M, Kitchener H, Segnan N, Gilham C, Giorgi-Rossi P, Berkhof J, Peto J, Meijer CJ; International HPV screening working group
Lancet 2014 Feb 8;383(9916):524-32. Epub 2013 Nov 3 doi: 10.1016/S0140-6736(13)62218-7. PMID: 24192252
Helm CW, Lorenz DJ, Meyer NJ, Rising WW, Wulff JL
Cochrane Database Syst Rev 2013 Jun 6;2013(6):CD003296. doi: 10.1002/14651858.CD003296.pub3. PMID: 23740788Free PMC Article
Grigsby PW
Curr Treat Options Oncol 2002 Apr;3(2):125-30. doi: 10.1007/s11864-002-0058-4. PMID: 12057075

Prognosis

Reyna-Hernández MA, Alarcón-Romero LDC, Ortiz-Ortiz J, Illades-Aguiar B, Jiménez-López MA, Ocampo-Bárcenas A, Morrugares-Ixtepan MO, Torres-Rojas FI
J Histochem Cytochem 2022 Jun;70(6):437-446. Epub 2022 May 26 doi: 10.1369/00221554221101662. PMID: 35615882Free PMC Article
Tewari KS, Monk BJ
J Clin Oncol 2019 Sep 20;37(27):2472-2489. Epub 2019 Aug 12 doi: 10.1200/JCO.18.02303. PMID: 31403858Free PMC Article
Javadi S, Menias CO, Karbasian N, Shaaban A, Shah K, Osman A, Jensen CT, Lubner MG, Gaballah AH, Elsayes KM
Radiographics 2018 Nov-Dec;38(7):2051-2068. Epub 2018 Oct 19 doi: 10.1148/rg.2018180149. PMID: 30339518
Huh WK, Joura EA, Giuliano AR, Iversen OE, de Andrade RP, Ault KA, Bartholomew D, Cestero RM, Fedrizzi EN, Hirschberg AL, Mayrand MH, Ruiz-Sternberg AM, Stapleton JT, Wiley DJ, Ferenczy A, Kurman R, Ronnett BM, Stoler MH, Cuzick J, Garland SM, Kjaer SK, Bautista OM, Haupt R, Moeller E, Ritter M, Roberts CC, Shields C, Luxembourg A
Lancet 2017 Nov 11;390(10108):2143-2159. Epub 2017 Sep 5 doi: 10.1016/S0140-6736(17)31821-4. PMID: 28886907
Ronco G, Dillner J, Elfström KM, Tunesi S, Snijders PJ, Arbyn M, Kitchener H, Segnan N, Gilham C, Giorgi-Rossi P, Berkhof J, Peto J, Meijer CJ; International HPV screening working group
Lancet 2014 Feb 8;383(9916):524-32. Epub 2013 Nov 3 doi: 10.1016/S0140-6736(13)62218-7. PMID: 24192252

Clinical prediction guides

Reyna-Hernández MA, Alarcón-Romero LDC, Ortiz-Ortiz J, Illades-Aguiar B, Jiménez-López MA, Ocampo-Bárcenas A, Morrugares-Ixtepan MO, Torres-Rojas FI
J Histochem Cytochem 2022 Jun;70(6):437-446. Epub 2022 May 26 doi: 10.1369/00221554221101662. PMID: 35615882Free PMC Article
Javed S, Sood S, Rai B, Bhattacharyya S, Bagga R, Srinivasan R
Indian J Med Res 2021 Aug;154(2):367-374. doi: 10.4103/ijmr.IJMR_709_20. PMID: 35295009Free PMC Article
Wijetunga NA, Ben-Dayan M, Tozour J, Burk RD, Schlecht NF, Einstein MH, Greally JM
Oncotarget 2016 Sep 20;7(38):62133-62143. doi: 10.18632/oncotarget.11390. PMID: 27557505Free PMC Article
Velázquez-Hernández N, Reyes-Romero MA, Barragán-Hernández M, Guerrero-Romero F, Rodríguez-Moran M, Aguilar-Durán M, Lazalde Medina B
Genet Mol Res 2015 Jun 10;14(2):6094-100. doi: 10.4238/2015.June.8.7. PMID: 26125810
Koyama T, Tamai K, Togashi K
Eur Radiol 2007 Aug;17(8):2009-19. Epub 2007 Jan 12 doi: 10.1007/s00330-006-0555-0. PMID: 17219142

Recent systematic reviews

Ogembo RK, Gona PN, Seymour AJ, Park HS, Bain PA, Maranda L, Ogembo JG
PLoS One 2015;10(4):e0122488. Epub 2015 Apr 14 doi: 10.1371/journal.pone.0122488. PMID: 25875167Free PMC Article
Helm CW, Lorenz DJ, Meyer NJ, Rising WW, Wulff JL
Cochrane Database Syst Rev 2013 Jun 6;2013(6):CD003296. doi: 10.1002/14651858.CD003296.pub3. PMID: 23740788Free PMC Article
Helm CW, Lorenz DJ, Meyer NJ, Rising WR, Wulff JL
Cochrane Database Syst Rev 2007 Oct 17;(4):CD003296. doi: 10.1002/14651858.CD003296.pub2. PMID: 17943787

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