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Lymphadenopathic Kaposi Sarcoma

MedGen UID:: 233630
•Concept ID:: C1334457
•: Neoplastic Process

Synonym:

Lymphadenopathic Kaposi's Sarcoma

Definition

A Kaposi sarcoma affecting the lymph nodes. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVLymphadenopathic Kaposi Sarcoma

Finding by Cause
- Infection
  - viral disease
    - DNA Virus Infections
      - Herpesvirus infection
        Kaposi sarcoma
        Lymphadenopathic Kaposi Sarcoma

Recent clinical studies

Etiology

Divergent clinical presentations and outcomes among children and adolescents with Kaposi sarcoma in Malawi and Tanzania.

Campbell LR, Silverstein A, Peckham-Gregory E, Kamiyango W, Villiera J, McAtee CL, Bacha JM, Kovarik CL, Mehta PS, Chanroo T, Kapesa A, Malingoti B, Mzikamanda R, Ozuah NW, Allen CE, Scheurer ME, El-Mallawany NK
HIV Med 2023 Jun;24(6):664-675. Epub 2023 Jan 10 doi: 10.1111/hiv.13455. PMID: 36627111 Free PMC Article

Navigating the heterogeneous landscape of pediatric Kaposi sarcoma.

Kamiyango W, Villiera J, Silverstein A, Peckham-Gregory E, Campbell LR, El-Mallawany NK
Cancer Metastasis Rev 2019 Dec;38(4):749-758. doi: 10.1007/s10555-019-09823-3. PMID: 31845111 Free PMC Article

KSHV viral load and Interleukin-6 in HIV-associated pediatric Kaposi sarcoma-Exploring the role of lytic activation in driving the unique clinical features seen in endemic regions.

El-Mallawany NK, Mehta PS, Kamiyango W, Villiera J, Peckham-Gregory EC, Kampani C, Krysiak R, Sanders MK, Caro-Vegas C, Eason AB, Ahmed S, Schutze GE, Martin SC, Kazembe PN, Scheurer ME, Dittmer DP
Int J Cancer 2019 Jan 1;144(1):110-116. Epub 2018 Oct 31 doi: 10.1002/ijc.31863. PMID: 30204240 Free PMC Article

Indolent lymphadenopathic Kaposi's sarcoma.

Schwartz RA, Brenden LD, Breeden JH, Lambert WC
J Surg Oncol 1987 Apr;34(4):243-7. doi: 10.1002/jso.2930340406. PMID: 3560958

Cutaneous and lymphadenopathic Kaposi's sarcoma in Africa and the USA with observations on persistent lymphadenopathy in homosexual men at risk for the acquired immunodeficiency syndrome.

Dorfman RF
Front Radiat Ther Oncol 1985;19:105-16. doi: 10.1159/000429350. PMID: 3884446

See all (8)

Diagnosis

S1 Guidelines for the Kaposi Sarcoma.

Esser S, Schöfer H, Hoffmann C, Claßen J, Kreuter A, Leiter U, Oette M, Becker JC, Ziemer M, Mosthaf F, Sirokay J, Ugurel S, Potthoff A, Helbig D, Bierhoff E, Schulz TF, Brockmeyer NH, Grabbe S
J Dtsch Dermatol Ges 2022 Jun;20(6):892-904. Epub 2022 Jun 3 doi: 10.1111/ddg.14788. PMID: 35657085

Navigating the heterogeneous landscape of pediatric Kaposi sarcoma.

Kamiyango W, Villiera J, Silverstein A, Peckham-Gregory E, Campbell LR, El-Mallawany NK
Cancer Metastasis Rev 2019 Dec;38(4):749-758. doi: 10.1007/s10555-019-09823-3. PMID: 31845111 Free PMC Article

Palisaded myofibroblastoma simulating chronic primary lymphadenopathic Kaposi's sarcoma.

Burns MK, Headington JT, Rasmussen JE
J Am Acad Dermatol 1991 Sep;25(3):566-8. doi: 10.1016/s0190-9622(08)80415-x. PMID: 1655839

AIDS-related lymphadenopathies.

Said JW
Semin Diagn Pathol 1988 Nov;5(4):365-75. PMID: 3064217

Indolent lymphadenopathic Kaposi's sarcoma.

Schwartz RA, Brenden LD, Breeden JH, Lambert WC
J Surg Oncol 1987 Apr;34(4):243-7. doi: 10.1002/jso.2930340406. PMID: 3560958

See all (13)

Therapy

Education and imaging. Gastrointestinal: Gastric involvement in disseminated lymphadenopathic Kaposi sarcoma.

Verma R, Toma AA, Boetticher NC, Strickler JG Jr
J Gastroenterol Hepatol 2015 Apr;30(4):654. doi: 10.1111/jgh.12881. PMID: 25776961

Clinical presentation and outcome of epidemic Kaposi sarcoma in Ugandan children.

Gantt S, Kakuru A, Wald A, Walusansa V, Corey L, Casper C, Orem J
Pediatr Blood Cancer 2010 May;54(5):670-4. doi: 10.1002/pbc.22369. PMID: 20205254 Free PMC Article

See all (2)

Prognosis

S1 Guidelines for the Kaposi Sarcoma.

Navigating the heterogeneous landscape of pediatric Kaposi sarcoma.

Kamiyango W, Villiera J, Silverstein A, Peckham-Gregory E, Campbell LR, El-Mallawany NK
Cancer Metastasis Rev 2019 Dec;38(4):749-758. doi: 10.1007/s10555-019-09823-3. PMID: 31845111 Free PMC Article

Kaposi's sarcoma in childhood: an analysis of 100 cases from Uganda and relationship to HIV infection.

Ziegler JL, Katongole-Mbidde E
Int J Cancer 1996 Jan 17;65(2):200-3. doi: 10.1002/(SICI)1097-0215(19960117)65:2<200::AID-IJC12>3.0.CO;2-H. PMID: 8567117

AIDS-related lymphadenopathies.

Said JW
Semin Diagn Pathol 1988 Nov;5(4):365-75. PMID: 3064217

Indolent lymphadenopathic Kaposi's sarcoma.

Schwartz RA, Brenden LD, Breeden JH, Lambert WC
J Surg Oncol 1987 Apr;34(4):243-7. doi: 10.1002/jso.2930340406. PMID: 3560958

See all (7)

Clinical prediction guides

Navigating the heterogeneous landscape of pediatric Kaposi sarcoma.

Kamiyango W, Villiera J, Silverstein A, Peckham-Gregory E, Campbell LR, El-Mallawany NK
Cancer Metastasis Rev 2019 Dec;38(4):749-758. doi: 10.1007/s10555-019-09823-3. PMID: 31845111 Free PMC Article

Clinical presentation and outcome of epidemic Kaposi sarcoma in Ugandan children.

Gantt S, Kakuru A, Wald A, Walusansa V, Corey L, Casper C, Orem J
Pediatr Blood Cancer 2010 May;54(5):670-4. doi: 10.1002/pbc.22369. PMID: 20205254 Free PMC Article

Kaposi's sarcoma in childhood: an analysis of 100 cases from Uganda and relationship to HIV infection.

Ziegler JL, Katongole-Mbidde E
Int J Cancer 1996 Jan 17;65(2):200-3. doi: 10.1002/(SICI)1097-0215(19960117)65:2<200::AID-IJC12>3.0.CO;2-H. PMID: 8567117

AIDS-related lymphadenopathies.

Said JW
Semin Diagn Pathol 1988 Nov;5(4):365-75. PMID: 3064217

Cutaneous and lymphadenopathic Kaposi's sarcoma in Africa and the USA with observations on persistent lymphadenopathy in homosexual men at risk for the acquired immunodeficiency syndrome.

Dorfman RF
Front Radiat Ther Oncol 1985;19:105-16. doi: 10.1159/000429350. PMID: 3884446

See all (12)