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Metastatic Malignant Neoplasm in the Iris

MedGen UID:
233699
Concept ID:
C1334728
Neoplastic Process
Synonyms: Metastatic Malignant Neoplasm to the Iris; Metastatic Neoplasm to the Iris; Metastatic Tumor to the Iris

Definition

A malignant neoplasm that has spread to the iris from another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Iris

Professional guidelines

PubMed

Kakkassery V MD, PhD, Coupland SE MD, PhD, Heindl LM MD, PhD, MSc
Surv Ophthalmol 2021 Jan-Feb;66(1):41-53. Epub 2020 Jun 23 doi: 10.1016/j.survophthal.2020.06.003. PMID: 32585164
Carvajal RD, Schwartz GK, Tezel T, Marr B, Francis JH, Nathan PD
Br J Ophthalmol 2017 Jan;101(1):38-44. Epub 2016 Aug 29 doi: 10.1136/bjophthalmol-2016-309034. PMID: 27574175Free PMC Article
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article

Recent clinical studies

Etiology

Weis E, Surgeoner B, Salopek TG, Cheng T, Hyrcza M, Kostaras X, Larocque M, McKinnon G, McWhae J, Menon G, Monzon J, Murtha AD, Walker J, Temple-Oberle C
Curr Oncol 2023 Dec 20;31(1):24-41. doi: 10.3390/curroncol31010002. PMID: 38275828Free PMC Article
Rusňák Š, Hecová L, Kasl Z, Sobotová M, Hauer L
Cesk Slov Oftalmol 2020 Winter;76(6):247-252. doi: 10.31348/2020/9. PMID: 33691424
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article
Yonekawa Y, Kim IK
Hematol Oncol Clin North Am 2012 Dec;26(6):1169-84. doi: 10.1016/j.hoc.2012.08.004. PMID: 23116575
Aerts I, Lumbroso-Le Rouic L, Gauthier-Villars M, Brisse H, Doz F, Desjardins L
Orphanet J Rare Dis 2006 Aug 25;1:31. doi: 10.1186/1750-1172-1-31. PMID: 16934146Free PMC Article

Diagnosis

Kakkassery V MD, PhD, Coupland SE MD, PhD, Heindl LM MD, PhD, MSc
Surv Ophthalmol 2021 Jan-Feb;66(1):41-53. Epub 2020 Jun 23 doi: 10.1016/j.survophthal.2020.06.003. PMID: 32585164
Rusňák Š, Hecová L, Kasl Z, Sobotová M, Hauer L
Cesk Slov Oftalmol 2020 Winter;76(6):247-252. doi: 10.31348/2020/9. PMID: 33691424
Dogrusöz M, Jager MJ, Damato B
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):186-196. doi: 10.22608/APO.201734. PMID: 28399342
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article
Aerts I, Lumbroso-Le Rouic L, Gauthier-Villars M, Brisse H, Doz F, Desjardins L
Orphanet J Rare Dis 2006 Aug 25;1:31. doi: 10.1186/1750-1172-1-31. PMID: 16934146Free PMC Article

Therapy

Helal C, Pobel C, Bayle A, Vasseur D, Nicotra C, Blanc-Durand F, Naoun N, Bernard-Tessier A, Patrikidou A, Colomba E, Flippot R, Fuerea A, Auger N, Ngo Camus M, Besse B, Lacroix L, Rouleau E, Ponce S, Italiano A, Loriot Y
Eur J Cancer 2023 Dec;195:113368. Epub 2023 Oct 6 doi: 10.1016/j.ejca.2023.113368. PMID: 37897866
Soares LR, Vilbert M, Rosa VDL, Oliveira JL, Deus MM, Freitas-Junior R
ESMO Open 2023 Aug;8(4):101613. Epub 2023 Jul 23 doi: 10.1016/j.esmoop.2023.101613. PMID: 37481956Free PMC Article
Ny L, Jespersen H, Karlsson J, Alsén S, Filges S, All-Eriksson C, Andersson B, Carneiro A, Helgadottir H, Levin M, Ljuslinder I, Olofsson Bagge R, Sah VR, Stierner U, Ståhlberg A, Ullenhag G, Nilsson LM, Nilsson JA
Nat Commun 2021 Aug 27;12(1):5155. doi: 10.1038/s41467-021-25332-w. PMID: 34453044Free PMC Article
Aldea M, Orillard E, Mansi L, Marabelle A, Scotte F, Lambotte O, Michot JM
Eur J Cancer 2020 Dec;141:239-251. Epub 2020 Nov 16 doi: 10.1016/j.ejca.2020.09.032. PMID: 33212339
Tanaka T, Tanaka M, Furusawa H, Kamada Y, Sagara Y, Anan K, Miyara K, Kai Y, Uga T, Tamura K, Mitsuyama S; KBC-SG (Kyushu Breast Cancer-Study Group)
Anticancer Res 2020 Aug;40(8):4779-4785. doi: 10.21873/anticanres.14480. PMID: 32727805

Prognosis

Soares LR, Vilbert M, Rosa VDL, Oliveira JL, Deus MM, Freitas-Junior R
ESMO Open 2023 Aug;8(4):101613. Epub 2023 Jul 23 doi: 10.1016/j.esmoop.2023.101613. PMID: 37481956Free PMC Article
Rusňák Š, Hecová L, Kasl Z, Sobotová M, Hauer L
Cesk Slov Oftalmol 2020 Winter;76(6):247-252. doi: 10.31348/2020/9. PMID: 33691424
Carvajal RD, Schwartz GK, Tezel T, Marr B, Francis JH, Nathan PD
Br J Ophthalmol 2017 Jan;101(1):38-44. Epub 2016 Aug 29 doi: 10.1136/bjophthalmol-2016-309034. PMID: 27574175Free PMC Article
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article
Aerts I, Lumbroso-Le Rouic L, Gauthier-Villars M, Brisse H, Doz F, Desjardins L
Orphanet J Rare Dis 2006 Aug 25;1:31. doi: 10.1186/1750-1172-1-31. PMID: 16934146Free PMC Article

Clinical prediction guides

Shao YF, Echegaray JJ, Singh N, Singh AD
Ophthalmol Retina 2019 Feb;3(2):186-193. Epub 2018 Sep 21 doi: 10.1016/j.oret.2018.09.007. PMID: 31014770
Georgalas I, Petrou P, Papaconstantinou D, Brouzas D, Koutsandrea C, Kanakis M
Surv Ophthalmol 2018 May-Jun;63(3):347-364. Epub 2017 Sep 5 doi: 10.1016/j.survophthal.2017.08.009. PMID: 28882598
Dogrusöz M, Jager MJ, Damato B
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):186-196. doi: 10.22608/APO.201734. PMID: 28399342
Kaliki S, Shields CL, Shields JA
Indian J Ophthalmol 2015 Feb;63(2):93-102. doi: 10.4103/0301-4738.154367. PMID: 25827538Free PMC Article
Aerts I, Lumbroso-Le Rouic L, Gauthier-Villars M, Brisse H, Doz F, Desjardins L
Orphanet J Rare Dis 2006 Aug 25;1:31. doi: 10.1186/1750-1172-1-31. PMID: 16934146Free PMC Article

Recent systematic reviews

Soares LR, Vilbert M, Rosa VDL, Oliveira JL, Deus MM, Freitas-Junior R
ESMO Open 2023 Aug;8(4):101613. Epub 2023 Jul 23 doi: 10.1016/j.esmoop.2023.101613. PMID: 37481956Free PMC Article
Fillbrunn M, Signorovitch J, André F, Wang I, Lorenzo I, Ridolfi A, Park J, Dua A, Rugo HS
BMC Cancer 2022 Sep 21;22(1):1002. doi: 10.1186/s12885-022-10078-5. PMID: 36131248Free PMC Article
Schmalfuss TR, Picetti E, Pakter HM
Arq Bras Oftalmol 2018 Jun;81(3):254-261. doi: 10.5935/0004-2749.20180051. PMID: 29924202
Nagtegaal ID, Knijn N, Hugen N, Marshall HC, Sugihara K, Tot T, Ueno H, Quirke P
J Clin Oncol 2017 Apr 1;35(10):1119-1127. Epub 2016 Dec 28 doi: 10.1200/JCO.2016.68.9091. PMID: 28029327
Wieser I, Wohlmuth C, Nunez CA, Duvic M
Am J Clin Dermatol 2016 Aug;17(4):319-27. doi: 10.1007/s40257-016-0192-6. PMID: 27138554

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