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Central nervous system leukemia

MedGen UID:
234102
Concept ID:
C1332884
Neoplastic Process
Synonyms: central nervous system leukaemia (disease); Central Nervous System Leukemia; central nervous system leukemia; central nervous system leukemia (disease); CNS leukaemia; CNS Leukemia; CNS leukemia; leukaemia (disease) of central nervous system; leukaemia of central nervous system; leukaemia of CNS; leukaemia of the central nervous system; leukaemia of the CNS; leukemia (disease) of central nervous system; Leukemia of Central Nervous System; leukemia of central nervous system; Leukemia of CNS; leukemia of CNS; Leukemia of the Central Nervous System; leukemia of the central nervous system; Leukemia of the CNS; leukemia of the CNS
 
Monarch Initiative: MONDO:0001606

Definition

Leukemia infiltrating the central nervous system structures. [from NCI]

Professional guidelines

PubMed

Buchmann S, Schrappe M, Baruchel A, Biondi A, Borowitz M, Campbell M, Cario G, Cazzaniga G, Escherich G, Harrison CJ, Heyman M, Hunger SP, Kiss C, Liu HC, Locatelli F, Loh ML, Manabe A, Mann G, Pieters R, Pui CH, Rives S, Schmiegelow K, Silverman LB, Stary J, Vora A, Brown P
Blood 2022 Mar 24;139(12):1785-1793. doi: 10.1182/blood.2021012328. PMID: 34192312Free PMC Article
He X, Xiao X, Li Q, Jiang Y, Cao Y, Sun R, Jin X, Yuan T, Meng J, Ma L, Lu W, Lyu C, Liu K, Zhao M
Leukemia 2019 Aug;33(8):2102-2104. Epub 2019 Mar 7 doi: 10.1038/s41375-019-0437-5. PMID: 30846865Free PMC Article
Band PR, Holland JF, Bernard J, Weil M, Walker M, Rall D
Cancer 1973 Oct;32(4):744-8. doi: 10.1002/1097-0142(197310)32:4<744::aid-cncr2820320402>3.0.co;2-j. PMID: 4201653

Recent clinical studies

Etiology

Buchmann S, Schrappe M, Baruchel A, Biondi A, Borowitz M, Campbell M, Cario G, Cazzaniga G, Escherich G, Harrison CJ, Heyman M, Hunger SP, Kiss C, Liu HC, Locatelli F, Loh ML, Manabe A, Mann G, Pieters R, Pui CH, Rives S, Schmiegelow K, Silverman LB, Stary J, Vora A, Brown P
Blood 2022 Mar 24;139(12):1785-1793. doi: 10.1182/blood.2021012328. PMID: 34192312Free PMC Article
Shen S, Chen X, Cai J, Yu J, Gao J, Hu S, Zhai X, Liang C, Ju X, Jiang H, Jin R, Wu X, Wang N, Tian X, Pan K, Jiang H, Sun L, Fang Y, Li CK, Hu Q, Yang M, Zhu Y, Zhang H, Li C, Pei D, Jeha S, Yang JJ, Cheng C, Tang J, Zhu X, Pui CH
JAMA Oncol 2020 Mar 1;6(3):358-366. doi: 10.1001/jamaoncol.2019.5868. PMID: 31944221Free PMC Article
Pinnix CC, Yahalom J, Specht L, Dabaja BS
Int J Radiat Oncol Biol Phys 2018 Sep 1;102(1):53-58. Epub 2018 Jun 6 doi: 10.1016/j.ijrobp.2018.05.067. PMID: 30102203
Lister A, Abrey LE, Sandlund JT
Hematology Am Soc Hematol Educ Program 2002:283-96. doi: 10.1182/asheducation-2002.1.283. PMID: 12446428
Evans AE, Gilbert ES, Zandstra R
Cancer 1970 Aug;26(2):404-9. doi: 10.1002/1097-0142(197008)26:2<404::aid-cncr2820260222>3.0.co;2-i. PMID: 5271211

Diagnosis

Buchmann S, Schrappe M, Baruchel A, Biondi A, Borowitz M, Campbell M, Cario G, Cazzaniga G, Escherich G, Harrison CJ, Heyman M, Hunger SP, Kiss C, Liu HC, Locatelli F, Loh ML, Manabe A, Mann G, Pieters R, Pui CH, Rives S, Schmiegelow K, Silverman LB, Stary J, Vora A, Brown P
Blood 2022 Mar 24;139(12):1785-1793. doi: 10.1182/blood.2021012328. PMID: 34192312Free PMC Article
Shen S, Chen X, Cai J, Yu J, Gao J, Hu S, Zhai X, Liang C, Ju X, Jiang H, Jin R, Wu X, Wang N, Tian X, Pan K, Jiang H, Sun L, Fang Y, Li CK, Hu Q, Yang M, Zhu Y, Zhang H, Li C, Pei D, Jeha S, Yang JJ, Cheng C, Tang J, Zhu X, Pui CH
JAMA Oncol 2020 Mar 1;6(3):358-366. doi: 10.1001/jamaoncol.2019.5868. PMID: 31944221Free PMC Article
Pagani JJ, Libshitz HI, Wallace S, Hayman LA
AJR Am J Roentgenol 1981 Dec;137(6):1195-201. doi: 10.2214/ajr.137.6.1195. PMID: 6976091
Miller DR
Pediatr Clin North Am 1980 May;27(2):269-91. doi: 10.1016/s0031-3955(16)33851-2. PMID: 6992074
Hustu HO, Aur RJ, Verzosa MS, Simone JV, Pinkel D
Cancer 1973 Sep;32(3):585-97. doi: 10.1002/1097-0142(197309)32:3<585::aid-cncr2820320311>3.0.co;2-k. PMID: 4516634

Therapy

Qi Y, Zhao M, Hu Y, Wang Y, Li P, Cao J, Shi M, Tan J, Zhang M, Xiao X, Xia J, Ma S, Qiao J, Yan Z, Li H, Pan B, Sang W, Li D, Li Z, Zhou J, Huang H, Liang A, Zheng J, Xu K
Blood 2022 Jun 9;139(23):3376-3386. doi: 10.1182/blood.2021013733. PMID: 35338773Free PMC Article
Buchmann S, Schrappe M, Baruchel A, Biondi A, Borowitz M, Campbell M, Cario G, Cazzaniga G, Escherich G, Harrison CJ, Heyman M, Hunger SP, Kiss C, Liu HC, Locatelli F, Loh ML, Manabe A, Mann G, Pieters R, Pui CH, Rives S, Schmiegelow K, Silverman LB, Stary J, Vora A, Brown P
Blood 2022 Mar 24;139(12):1785-1793. doi: 10.1182/blood.2021012328. PMID: 34192312Free PMC Article
Shen S, Chen X, Cai J, Yu J, Gao J, Hu S, Zhai X, Liang C, Ju X, Jiang H, Jin R, Wu X, Wang N, Tian X, Pan K, Jiang H, Sun L, Fang Y, Li CK, Hu Q, Yang M, Zhu Y, Zhang H, Li C, Pei D, Jeha S, Yang JJ, Cheng C, Tang J, Zhu X, Pui CH
JAMA Oncol 2020 Mar 1;6(3):358-366. doi: 10.1001/jamaoncol.2019.5868. PMID: 31944221Free PMC Article
Miller DR
Pediatr Clin North Am 1980 May;27(2):269-91. doi: 10.1016/s0031-3955(16)33851-2. PMID: 6992074
Bergevin PR
N Y State J Med 1975 Feb;75(3):367-71. PMID: 1094335

Prognosis

Vanner RJ, Dobson SM, Gan OI, McLeod J, Schoof EM, Grandal I, Wintersinger JA, Garcia-Prat L, Hosseini M, Xie SZ, Jin L, Mbong N, Voisin V, Chan-Seng-Yue M, Kennedy JA, Waanders E, Morris Q, Porse B, Chan SM, Guidos CJ, Danska JS, Minden MD, Mullighan CG, Dick JE
Blood Cancer Discov 2022 Jan;3(1):16-31. Epub 2021 Oct 11 doi: 10.1158/2643-3230.BCD-20-0216. PMID: 35019858Free PMC Article
Bharucha J, Cao Q, Sachs Z, Smith A, Williams S, Amin K, Bachanova V, Warlick E, Brunstein C, Weisdorf D, Bejanyan N
Hematol Oncol Stem Cell Ther 2021 Sep;14(3):240-245. Epub 2020 Nov 24 doi: 10.1016/j.hemonc.2020.11.004. PMID: 33271117Free PMC Article
Miller DR
Pediatr Clin North Am 1980 May;27(2):269-91. doi: 10.1016/s0031-3955(16)33851-2. PMID: 6992074
Sullivan MP
Proc Natl Cancer Conf 1972;7:593-9. PMID: 4764928
Evans AE, Gilbert ES, Zandstra R
Cancer 1970 Aug;26(2):404-9. doi: 10.1002/1097-0142(197008)26:2<404::aid-cncr2820260222>3.0.co;2-i. PMID: 5271211

Clinical prediction guides

Lister A, Abrey LE, Sandlund JT
Hematology Am Soc Hematol Educ Program 2002:283-96. doi: 10.1182/asheducation-2002.1.283. PMID: 12446428
Millot F, Dhondt JL, Mazingue F, Mechinaud F, Auget JL, Bauters F, Harousseau JL
Leuk Lymphoma 1993 Mar;9(4-5):351-6. doi: 10.3109/10428199309148533. PMID: 8348070
Bleyer WA
Pediatr Clin North Am 1988 Aug;35(4):789-814. doi: 10.1016/s0031-3955(16)36510-5. PMID: 3047654
Bleyer WA
Cancer Drug Deliv 1984;1(2):157-67. doi: 10.1089/cdd.1984.1.157. PMID: 6399986
Rubinstein JL, Herman MM, Long TF, Wilbur JR
Acta Neuropathol Suppl 1975;Suppl 6:251-5. doi: 10.1007/978-3-662-08456-4_44. PMID: 1057358

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