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Childhood testicular mixed embryonal carcinoma and teratoma

MedGen UID:
234137
•Concept ID:
C1333008
•
Neoplastic Process
Synonyms: Childhood Teratocarcinoma of Testis; childhood teratocarcinoma of testis; Childhood Teratocarcinoma of the Testis; childhood teratocarcinoma of the testis; Childhood Testicular Mixed Embryonal Carcinoma and Teratoma; childhood testicular mixed embryonal carcinoma and teratoma; Childhood Testicular Teratocarcinoma; childhood testicular teratocarcinoma; paediatric testicular teratocarcinoma; Pediatric Testicular Teratocarcinoma; pediatric testicular teratocarcinoma
 
Monarch Initiative: MONDO:0003888

Definition

A malignant testicular mixed germ cell neoplasm that occurs during childhood. It is characterized by the presence of embryonal carcinoma and teratoma components. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood testicular mixed embryonal carcinoma and teratoma

Professional guidelines

PubMed

Testicular germ cell tumors in childhood: treatment results of 52 patients.
Güler E, Tezer Kutluk M, Büyükpamukçu N, Caglar M, Varan A, Akyüz C, Büyükpamukçu M
Pediatr Hematol Oncol 2004 Jan-Feb;21(1):49-56. PMID: 14660306

Recent clinical studies

Etiology

Intratubular germ cell neoplasia of the testis: a brief review.
Al-Hussain T, Bakshi N, Akhtar M
Adv Anat Pathol 2015 May;22(3):202-12. doi: 10.1097/PAP.0000000000000066. PMID: 25844678
Epidemiologic analysis of 1,442 children and adolescents registered in the German germ cell tumor protocols.
Schneider DT, Calaminus G, Koch S, Teske C, Schmidt P, Haas RJ, Harms D, Göbel U
Pediatr Blood Cancer 2004 Feb;42(2):169-75. doi: 10.1002/pbc.10321. PMID: 14752882
Testicular germ cell tumors in childhood: treatment results of 52 patients.
Güler E, Tezer Kutluk M, Büyükpamukçu N, Caglar M, Varan A, Akyüz C, Büyükpamukçu M
Pediatr Hematol Oncol 2004 Jan-Feb;21(1):49-56. PMID: 14660306
Clinical stage I nonseminomatous germ cell tumors of the testis in childhood and adolescence: an analysis of 31 cases.
Terenziani M, Piva L, Spreafico F, Salvioni R, Massimino M, Luksch R, Cefalo G, Casanova M, Ferrari A, Polastri D, Mazza E, Bellani FF, Nicolai N
J Pediatr Hematol Oncol 2002 Aug-Sep;24(6):454-8. doi: 10.1097/00043426-200208000-00009. PMID: 12218592
Nongerminomatous malignant germ cell tumors in children. A review of 89 cases from the Pediatric Oncology Group, 1971-1984.
Hawkins EP, Finegold MJ, Hawkins HK, Krischer JP, Starling KA, Weinberg A
Cancer 1986 Dec 15;58(12):2579-84. doi: 10.1002/1097-0142(19861215)58:12<2579::aid-cncr2820581204>3.0.co;2-v. PMID: 3022907

Diagnosis

Epidemiologic analysis of 1,442 children and adolescents registered in the German germ cell tumor protocols.
Schneider DT, Calaminus G, Koch S, Teske C, Schmidt P, Haas RJ, Harms D, Göbel U
Pediatr Blood Cancer 2004 Feb;42(2):169-75. doi: 10.1002/pbc.10321. PMID: 14752882
Testicular germ cell tumors in childhood: treatment results of 52 patients.
Güler E, Tezer Kutluk M, Büyükpamukçu N, Caglar M, Varan A, Akyüz C, Büyükpamukçu M
Pediatr Hematol Oncol 2004 Jan-Feb;21(1):49-56. PMID: 14660306

Therapy

Testicular germ cell tumors in childhood: treatment results of 52 patients.
Güler E, Tezer Kutluk M, Büyükpamukçu N, Caglar M, Varan A, Akyüz C, Büyükpamukçu M
Pediatr Hematol Oncol 2004 Jan-Feb;21(1):49-56. PMID: 14660306
Clinical stage I nonseminomatous germ cell tumors of the testis in childhood and adolescence: an analysis of 31 cases.
Terenziani M, Piva L, Spreafico F, Salvioni R, Massimino M, Luksch R, Cefalo G, Casanova M, Ferrari A, Polastri D, Mazza E, Bellani FF, Nicolai N
J Pediatr Hematol Oncol 2002 Aug-Sep;24(6):454-8. doi: 10.1097/00043426-200208000-00009. PMID: 12218592

Prognosis

Clinical stage I nonseminomatous germ cell tumors of the testis in childhood and adolescence: an analysis of 31 cases.
Terenziani M, Piva L, Spreafico F, Salvioni R, Massimino M, Luksch R, Cefalo G, Casanova M, Ferrari A, Polastri D, Mazza E, Bellani FF, Nicolai N
J Pediatr Hematol Oncol 2002 Aug-Sep;24(6):454-8. doi: 10.1097/00043426-200208000-00009. PMID: 12218592
Nongerminomatous malignant germ cell tumors in children. A review of 89 cases from the Pediatric Oncology Group, 1971-1984.
Hawkins EP, Finegold MJ, Hawkins HK, Krischer JP, Starling KA, Weinberg A
Cancer 1986 Dec 15;58(12):2579-84. doi: 10.1002/1097-0142(19861215)58:12<2579::aid-cncr2820581204>3.0.co;2-v. PMID: 3022907

Clinical prediction guides

Epidemiologic analysis of 1,442 children and adolescents registered in the German germ cell tumor protocols.
Schneider DT, Calaminus G, Koch S, Teske C, Schmidt P, Haas RJ, Harms D, Göbel U
Pediatr Blood Cancer 2004 Feb;42(2):169-75. doi: 10.1002/pbc.10321. PMID: 14752882
Clinical stage I nonseminomatous germ cell tumors of the testis in childhood and adolescence: an analysis of 31 cases.
Terenziani M, Piva L, Spreafico F, Salvioni R, Massimino M, Luksch R, Cefalo G, Casanova M, Ferrari A, Polastri D, Mazza E, Bellani FF, Nicolai N
J Pediatr Hematol Oncol 2002 Aug-Sep;24(6):454-8. doi: 10.1097/00043426-200208000-00009. PMID: 12218592

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