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Peripheral Vascular Insufficiency

MedGen UID:
234670
•Concept ID:
C1401086
•
Disease or Syndrome
Synonym: Peripheral vascular insufficiency

Definition

A condition in which there is inadequate blood flow through the peripheral blood vessels due to intrinsic disease of the vasculature. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeripheral Vascular Insufficiency

Professional guidelines

PubMed

Diagnosis and surgical management of popliteal artery entrapment syndrome.
Goh BK, Tay KH, Tan SG
ANZ J Surg 2005 Oct;75(10):869-73. doi: 10.1111/j.1445-2197.2005.03555.x. PMID: 16176228
Clinical profile and treatment outcome of diabetic ketoacidosis.
Matoo VK, Nalini K, Dash RJ
J Assoc Physicians India 1991 May;39(5):379-81. PMID: 1960152
The management of peripheral vascular insufficiency in arteriosclerosis obliterans.
KONWALER BE, LEIK DW, MASSELL TB
Calif Med 1948 Nov;69(5):382-5. PMID: 18888463Free PMC Article

Recent clinical studies

Etiology

Bone metabolism and vascular calcification.
Danilevicius CF, Lopes JB, Pereira RM
Braz J Med Biol Res 2007 Apr;40(4):435-42. doi: 10.1590/s0100-879x2007000400001. PMID: 17401486
Functional outcome of below-knee amputation in peripheral vascular insufficiency. A multicenter review.
Pinzur MS, Gottschalk F, Smith D, Shanfield S, de Andrade R, Osterman H, Roberts JR, Orlando-Crombleholme P, Larsen J, Rappazzini P
Clin Orthop Relat Res 1993 Jan;(286):247-9. PMID: 8425353
Sciatic nerve block for residual limb pain following below-knee amputation.
Pinzur MS
Contemp Orthop 1991 Mar;22(3):290-2. PMID: 10147554
Complications of 100 consecutive local fasciocutaneous flaps.
Hallock GG
Plast Reconstr Surg 1991 Aug;88(2):264-8. doi: 10.1097/00006534-199108000-00015. PMID: 1852819
Amputations of the leg for peripheral vascular insufficiency.
Burgess EM, Romano RL, Zettl JH, Schrock RD Jr
J Bone Joint Surg Am 1971 Jul;53(5):874-90. PMID: 4934074

Diagnosis

Knowledge of the Warning Signs of Foot Ulcer Deterioration Among Patients With Diabetes.
Chin YF, Yeh JT, Yu HY, Weng LC
J Nurs Res 2018 Dec;26(6):420-426. doi: 10.1097/jnr.0000000000000258. PMID: 30395022
Rosai-Dorfman Disease Presenting as Peripheral Vascular Insufficiency.
Baldi I, Belcastro M, Rossi M, Rossi A, Minacci C, Natale A
Ann Vasc Surg 2018 Nov;53:267.e5-267.e9. Epub 2018 Aug 20 doi: 10.1016/j.avsg.2018.05.031. PMID: 30012448
Study of the association of adrenomedullin and basic-fibroblast growth factors with the peripheral arterial blood flow and endothelial dysfunction biomarkers in type 2 diabetic patients with peripheral vascular insufficiency.
Alrouq FA, Al-Masri AA, Al-Dokhi LM, Alregaiey KA, Bayoumy NM, Zakareia FA
J Biomed Sci 2014 Oct 7;21(1):94. doi: 10.1186/s12929-014-0094-y. PMID: 25287126Free PMC Article
The use of transcutaneous oxygen tension measurements in the diagnosis of peripheral vascular insufficiency.
Byrne P, Provan JL, Ameli FM, Jones DP
Ann Surg 1984 Aug;200(2):159-65. doi: 10.1097/00000658-198408000-00007. PMID: 6465970Free PMC Article
Office diagnosis of peripheral vascular insufficiency.
REDISCH W
J Med Soc N J 1949 Jan;46(1):4-9. PMID: 18104823

Therapy

Ergotism and factitious hypotension associated with interaction of ergotamine with CYP3A4 inhibitors.
Srisuma S, Lavonas EJ, Wananukul W
Clin Toxicol (Phila) 2014 Aug;52(7):674-7. Epub 2014 Jun 30 doi: 10.3109/15563650.2014.933230. PMID: 24978905
Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed mice.
Baltgalvis KA, White K, Li W, Claypool MD, Lang W, Alcantara R, Singh BK, Friera AM, McLaughlin J, Hansen D, McCaughey K, Nguyen H, Smith IJ, Godinez G, Shaw SJ, Goff D, Singh R, Markovtsov V, Sun TQ, Jenkins Y, Uy G, Li Y, Pan A, Gururaja T, Lau D, Park G, Hitoshi Y, Payan DG, Kinsella TM
Am J Physiol Heart Circ Physiol 2014 Apr 15;306(8):H1128-45. Epub 2014 Feb 21 doi: 10.1152/ajpheart.00839.2013. PMID: 24561866Free PMC Article
Complications of 100 consecutive local fasciocutaneous flaps.
Hallock GG
Plast Reconstr Surg 1991 Aug;88(2):264-8. doi: 10.1097/00006534-199108000-00015. PMID: 1852819
Self-induced myocardial infarction.
Carr P
Postgrad Med J 1981 Oct;57(672):654-5. doi: 10.1136/pgmj.57.672.654. PMID: 6801635Free PMC Article
Cinnarizine in peripheral vascular insufficiency. Studies on blood flow, muscle capacity, and vascular tone.
Schuermans V, Boermans A, Geivers H, Jageneau A, Brugmans J
Arzneimittelforschung 1971 Oct;21(10):1541-3. PMID: 5171882

Prognosis

Study of the association of adrenomedullin and basic-fibroblast growth factors with the peripheral arterial blood flow and endothelial dysfunction biomarkers in type 2 diabetic patients with peripheral vascular insufficiency.
Alrouq FA, Al-Masri AA, Al-Dokhi LM, Alregaiey KA, Bayoumy NM, Zakareia FA
J Biomed Sci 2014 Oct 7;21(1):94. doi: 10.1186/s12929-014-0094-y. PMID: 25287126Free PMC Article
Ergotism and factitious hypotension associated with interaction of ergotamine with CYP3A4 inhibitors.
Srisuma S, Lavonas EJ, Wananukul W
Clin Toxicol (Phila) 2014 Aug;52(7):674-7. Epub 2014 Jun 30 doi: 10.3109/15563650.2014.933230. PMID: 24978905
Dynamic fluorescence imaging of indocyanine green for reliable and sensitive diagnosis of peripheral vascular insufficiency.
Kang Y, Lee J, Kwon K, Choi C
Microvasc Res 2010 Dec;80(3):552-5. Epub 2010 Jul 15 doi: 10.1016/j.mvr.2010.07.004. PMID: 20637783
Sciatic nerve block for residual limb pain following below-knee amputation.
Pinzur MS
Contemp Orthop 1991 Mar;22(3):290-2. PMID: 10147554
Amputations of the leg for peripheral vascular insufficiency.
Burgess EM, Romano RL, Zettl JH, Schrock RD Jr
J Bone Joint Surg Am 1971 Jul;53(5):874-90. PMID: 4934074

Clinical prediction guides

Comparing near infrared spectroscopy and transcutaneous oxygen measurement in hard-to-heal wounds: a pilot study.
Serena TE, Yaakov R, Serena L, Mayhugh T, Harrell K
J Wound Care 2020 Jun 1;29(Sup6):S4-S9. doi: 10.12968/jowc.2020.29.Sup6.S4. PMID: 32530756
Study of the association of adrenomedullin and basic-fibroblast growth factors with the peripheral arterial blood flow and endothelial dysfunction biomarkers in type 2 diabetic patients with peripheral vascular insufficiency.
Alrouq FA, Al-Masri AA, Al-Dokhi LM, Alregaiey KA, Bayoumy NM, Zakareia FA
J Biomed Sci 2014 Oct 7;21(1):94. doi: 10.1186/s12929-014-0094-y. PMID: 25287126Free PMC Article
Dynamic fluorescence imaging of indocyanine green for reliable and sensitive diagnosis of peripheral vascular insufficiency.
Kang Y, Lee J, Kwon K, Choi C
Microvasc Res 2010 Dec;80(3):552-5. Epub 2010 Jul 15 doi: 10.1016/j.mvr.2010.07.004. PMID: 20637783
Leg pain and platelet aggregates in thrombocythemic myeloproliferative disease.
Salem HH, van der Weyden MB, Koutts J, Firkin BG
JAMA 1980 Sep 5;244(10):1122-3. PMID: 7411766
Effects of long-term treatment with suloctidil on blood viscosity, erythrocyte deformability and total fibrinogen plasma levels in diabetic patients.
Roncucci R, De Hertogh R, Dormandy JA, Doumont J, Gurewich V, Lambelin G, Lansen J, Rottiers R, Souridis E, Van Stalle F, Versee L
Arzneimittelforschung 1979;29(4):682-4. PMID: 582768

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