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Mediastinal extraskeletal osteosarcoma

MedGen UID:
235314
•Concept ID:
C1334675
•
Neoplastic Process
Synonyms: Mediastinal Extraskeletal Osteosarcoma; mediastinal extraskeletal osteosarcoma; Mediastinal Osteogenic Sarcoma; mediastinal osteogenic sarcoma; Mediastinal Osteosarcoma; mediastinal osteosarcoma; mediastinum osteosarcoma (disease); Osteogenic Sarcoma of Mediastinum; osteogenic sarcoma of mediastinum; Osteogenic Sarcoma of the Mediastinum; osteogenic sarcoma of the mediastinum; Osteosarcoma of Mediastinum; osteosarcoma of mediastinum; Osteosarcoma of the Mediastinum; osteosarcoma of the mediastinum
 
Monarch Initiative: MONDO:0003808

Definition

An osteosarcoma arising from the mediastinum. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMediastinal extraskeletal osteosarcoma

Recent clinical studies

Etiology

Multiple Ewing Sarcoma/Primitive Neuroectodermal Tumors in the Mediastinum: A Case Report and Literature Review.
Bae SH, Hwang JH, Da Nam B, Kim HJ, Kim KU, Kim DW, Choi IH
Medicine (Baltimore) 2016 Feb;95(7):e2725. doi: 10.1097/MD.0000000000002725. PMID: 26886614Free PMC Article
Extraskeletal Ewing's sarcoma presenting as a mediastinal mass.
Halliday J, Soon SY, Monaghan H, Walker WS, Zamvar V
Ann Thorac Surg 2010 Sep;90(3):1016-7. doi: 10.1016/j.athoracsur.2010.01.083. PMID: 20732541
Extraskeletal Ewing's sarcoma/primitive neuroectodermal tumor of the posterior mediastinum with t(11;22)(q24;q12).
Manduch M, Dexter DF, Ellis PM, Reid K, Isotalo PA
Tumori 2008 Nov-Dec;94(6):888-91. doi: 10.1177/030089160809400623. PMID: 19267114
Extraskeletal osteosarcoma of the mediastinum after treatment of a mediastinal germ-cell tumor.
Ulusakarya A, Terrier P, Regnard JF, de Montpreville V, Munck JN
Am J Clin Oncol 1999 Dec;22(6):609-14. doi: 10.1097/00000421-199912000-00013. PMID: 10597747
Extraskeletal osteosarcoma of the mediastinum associated with long-term patient survival. A case report.
De Nictolis M, Goteri G, Brancorsini D, Giannulis I, Prete E, Fabris G
Anticancer Res 1995 Nov-Dec;15(6B):2785-9. PMID: 8669865

Diagnosis

Surgery and Proton Beam Therapy for Mediastinal Extraskeletal Osteosarcoma.
Shimizu N, Tanaka Y, Demizu Y, Okimoto T, Maniwa Y
Ann Thorac Surg 2019 Nov;108(5):e289-e291. Epub 2019 Apr 26 doi: 10.1016/j.athoracsur.2019.03.075. PMID: 31034825
Extraskeletal osteosarcoma arising in anterior mediastinum: brief report with a review of the literature.
Hishida T, Yoshida J, Nishimura M, Ishii G, Nakao M, Nagai K
J Thorac Oncol 2009 Jul;4(7):927-9. doi: 10.1097/JTO.0b013e3181a52c63. PMID: 19550248
Extraskeletal Ewing's sarcoma.
El-Essawy MT
Saudi Med J 2009 Jun;30(6):840-3. PMID: 19526172
Extraskeletal osteosarcoma of the mediastinum after treatment of a mediastinal germ-cell tumor.
Ulusakarya A, Terrier P, Regnard JF, de Montpreville V, Munck JN
Am J Clin Oncol 1999 Dec;22(6):609-14. doi: 10.1097/00000421-199912000-00013. PMID: 10597747
Extraskeletal osteogenic sarcoma of the mediastinum.
Greenwood SM, Meschter SC
Arch Pathol Lab Med 1989 Apr;113(4):430-3. PMID: 2650655

Therapy

Extraskeletal osteosarcoma of the mediastinum after treatment of a mediastinal germ-cell tumor.
Ulusakarya A, Terrier P, Regnard JF, de Montpreville V, Munck JN
Am J Clin Oncol 1999 Dec;22(6):609-14. doi: 10.1097/00000421-199912000-00013. PMID: 10597747
Mediastinal osteosarcoma with extension to lungs in a patient treated for Hodgkin's disease.
Catanese J, Dutcher JP, Dorfman HD, Andres DF, Wiernik PH
Cancer 1988 Nov 15;62(10):2252-7. doi: 10.1002/1097-0142(19881115)62:10<2252::aid-cncr2820621030>3.0.co;2-2. PMID: 3052784

Prognosis

Surgery and Proton Beam Therapy for Mediastinal Extraskeletal Osteosarcoma.
Shimizu N, Tanaka Y, Demizu Y, Okimoto T, Maniwa Y
Ann Thorac Surg 2019 Nov;108(5):e289-e291. Epub 2019 Apr 26 doi: 10.1016/j.athoracsur.2019.03.075. PMID: 31034825
Low-grade extraskeletal osteosarcoma of the mediastinum: report of a case and review of literature.
Yu H, Wu Z, Cui Y, Huang J
Int J Clin Exp Pathol 2015;8(3):3279-81. Epub 2015 Mar 1 PMID: 26045852Free PMC Article
Extraskeletal osteosarcoma arising in anterior mediastinum: brief report with a review of the literature.
Hishida T, Yoshida J, Nishimura M, Ishii G, Nakao M, Nagai K
J Thorac Oncol 2009 Jul;4(7):927-9. doi: 10.1097/JTO.0b013e3181a52c63. PMID: 19550248
Extraskeletal osteosarcoma of the mediastinum after treatment of a mediastinal germ-cell tumor.
Ulusakarya A, Terrier P, Regnard JF, de Montpreville V, Munck JN
Am J Clin Oncol 1999 Dec;22(6):609-14. doi: 10.1097/00000421-199912000-00013. PMID: 10597747
Extraskeletal osteogenic sarcoma of the mediastinum.
Greenwood SM, Meschter SC
Arch Pathol Lab Med 1989 Apr;113(4):430-3. PMID: 2650655

Clinical prediction guides

Lymph node metastasis of soft tissue tumors: a cytomorphologic study.
Loya AC, Prayaga AK, Arora A, Sundaram C, Rao IS, Uppin SG, Raju GS, Surath A, Rajappa RS
Acta Cytol 2007 Mar-Apr;51(2):153-60. doi: 10.1159/000325708. PMID: 17425195

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