U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Carcinoma of supraglottis

MedGen UID:
266243
•Concept ID:
C1299240
•
Neoplastic Process
Synonyms: Cancer of Supraglottis; cancer of supraglottis; Cancer of the Supraglottis; cancer of the supraglottis; carcinoma of supraglottic part of larynx; Carcinoma of Supraglottis; carcinoma of supraglottis; Carcinoma of the Supraglottis; carcinoma of the supraglottis; Supraglottic Cancer; supraglottic cancer; Supraglottic Carcinoma; supraglottic carcinoma; supraglottic part of larynx carcinoma; supraglottic throat cancer; Supraglottis Carcinoma; supraglottis carcinoma
SNOMED CT: Carcinoma of supraglottis (372105009)
 
Monarch Initiative: MONDO:0004357

Definition

A carcinoma of the larynx that arises from the supraglottic area. [from NCI]

Professional guidelines

PubMed

Treatment of early-stage laryngeal cancer: A comparison of treatment options.
Baird BJ, Sung CK, Beadle BM, Divi V
Oral Oncol 2018 Dec;87:8-16. Epub 2018 Oct 16 doi: 10.1016/j.oraloncology.2018.09.012. PMID: 30527248
Management of cancer of the supraglottis.
Scola B, Fernández-Vega M, Martínez T, Fernández-Vega S, Ramirez C
Otolaryngol Head Neck Surg 2001 Feb;124(2):195-8. doi: 10.1067/mhn.2001.112202. PMID: 11226956
Basaloid squamous cell carcinoma of the head and neck: clinicopathological features and differential diagnosis.
Barnes L, Ferlito A, Altavilla G, MacMillan C, Rinaldo A, Doglioni C
Ann Otol Rhinol Laryngol 1996 Jan;105(1):75-82. doi: 10.1177/000348949610500115. PMID: 8546432

Recent clinical studies

Etiology

Epidemiological, clinical and oncological outcomes of laryngeal verrucous carcinomas: a systematic review.
Lechien JR, Hans S
J Otolaryngol Head Neck Surg 2023 Dec 13;52(1):81. doi: 10.1186/s40463-023-00666-1. PMID: 38093339Free PMC Article
Mu-Opioid Receptor Expression in Laryngeal Cancer.
Lahav Y, Cohen O, Huszar M, Levy I, Cata JP, Halperin D, Shoffel-Havakuk H
J Voice 2023 May;37(3):433-439. Epub 2021 Mar 7 doi: 10.1016/j.jvoice.2021.02.018. PMID: 33750623
Supraglottic Squamous Cell Carcinoma: A Population-Based Study of 22,675 Cases.
Patel TD, Echanique KA, Yip C, Hsueh WD, Baredes S, Park RCW, Eloy JA
Laryngoscope 2019 Aug;129(8):1822-1827. Epub 2018 Dec 11 doi: 10.1002/lary.27592. PMID: 30536822
Pharyngotomy in head and neck squamous cell carcinoma: functional and oncological aspects.
Remmert C, Mansour N, Hofauer B, Scherer EQ, Bas M, Bier H, Knopf A
Acta Otolaryngol 2017 Dec;137(12):1281-1287. Epub 2017 Jul 25 doi: 10.1080/00016489.2017.1355564. PMID: 28743201
Management of cancer of the supraglottis.
Scola B, Fernández-Vega M, Martínez T, Fernández-Vega S, Ramirez C
Otolaryngol Head Neck Surg 2001 Feb;124(2):195-8. doi: 10.1067/mhn.2001.112202. PMID: 11226956

Diagnosis

Supraglottic Squamous Cell Carcinoma: A Population-Based Study of 22,675 Cases.
Patel TD, Echanique KA, Yip C, Hsueh WD, Baredes S, Park RCW, Eloy JA
Laryngoscope 2019 Aug;129(8):1822-1827. Epub 2018 Dec 11 doi: 10.1002/lary.27592. PMID: 30536822
Salivary duct carcinoma of the supraglottis with a distinct presentation: A case report and literature review.
Hsu CC, Li WY, Chu PY
Medicine (Baltimore) 2018 Mar;97(11):e0095. doi: 10.1097/MD.0000000000010095. PMID: 29538201Free PMC Article
NUT midline carcinoma of the larynx: an international series and review of the literature.
Hellquist H, French CA, Bishop JA, Coca-Pelaz A, Propst EJ, Paiva Correia A, Ngan BY, Grant R, Cipriani NA, Vokes D, Henrique R, Pardal F, Vizcaino JR, Rinaldo A, Ferlito A
Histopathology 2017 May;70(6):861-868. Epub 2017 Feb 21 doi: 10.1111/his.13143. PMID: 27926786Free PMC Article
Basaloid squamous cell carcinoma of the head and neck: clinicopathological features and differential diagnosis.
Barnes L, Ferlito A, Altavilla G, MacMillan C, Rinaldo A, Doglioni C
Ann Otol Rhinol Laryngol 1996 Jan;105(1):75-82. doi: 10.1177/000348949610500115. PMID: 8546432
Controversies in the diagnosis and treatment of early carcinoma of the larynx.
Loré JM Jr
Semin Surg Oncol 1991 Jan-Feb;7(1):31-7. doi: 10.1002/ssu.2980070108. PMID: 2003183

Therapy

Advances in Organ Preservation for Laryngeal Cancer.
Campbell G, Glazer TA, Kimple RJ, Bruce JY
Curr Treat Options Oncol 2022 Apr;23(4):594-608. Epub 2022 Mar 18 doi: 10.1007/s11864-022-00945-5. PMID: 35303749Free PMC Article
Treatment of early-stage laryngeal cancer: A comparison of treatment options.
Baird BJ, Sung CK, Beadle BM, Divi V
Oral Oncol 2018 Dec;87:8-16. Epub 2018 Oct 16 doi: 10.1016/j.oraloncology.2018.09.012. PMID: 30527248
Salivary duct carcinoma of the supraglottis with a distinct presentation: A case report and literature review.
Hsu CC, Li WY, Chu PY
Medicine (Baltimore) 2018 Mar;97(11):e0095. doi: 10.1097/MD.0000000000010095. PMID: 29538201Free PMC Article
Basaloid squamous cell carcinoma of the larynx--A systematic review.
Thankappan K
Auris Nasus Larynx 2012 Aug;39(4):397-401. Epub 2011 Aug 24 doi: 10.1016/j.anl.2011.07.018. PMID: 21868181
Complications of supraglottic laryngectomy for carcinomas of the supraglottis and the base of the tongue.
Suarez C, Rodrigo JP, Herranz J, Diaz C, Fernandez JA
Clin Otolaryngol Allied Sci 1996 Feb;21(1):87-90. doi: 10.1111/j.1365-2273.1996.tb01032.x. PMID: 8674231

Prognosis

Treatment of early-stage laryngeal cancer: A comparison of treatment options.
Baird BJ, Sung CK, Beadle BM, Divi V
Oral Oncol 2018 Dec;87:8-16. Epub 2018 Oct 16 doi: 10.1016/j.oraloncology.2018.09.012. PMID: 30527248
Salivary duct carcinoma of the supraglottis with a distinct presentation: A case report and literature review.
Hsu CC, Li WY, Chu PY
Medicine (Baltimore) 2018 Mar;97(11):e0095. doi: 10.1097/MD.0000000000010095. PMID: 29538201Free PMC Article
Basaloid squamous cell carcinoma of the larynx--A systematic review.
Thankappan K
Auris Nasus Larynx 2012 Aug;39(4):397-401. Epub 2011 Aug 24 doi: 10.1016/j.anl.2011.07.018. PMID: 21868181
Management of cancer of the supraglottis.
Scola B, Fernández-Vega M, Martínez T, Fernández-Vega S, Ramirez C
Otolaryngol Head Neck Surg 2001 Feb;124(2):195-8. doi: 10.1067/mhn.2001.112202. PMID: 11226956
Basaloid squamous cell carcinoma of the head and neck: clinicopathological features and differential diagnosis.
Barnes L, Ferlito A, Altavilla G, MacMillan C, Rinaldo A, Doglioni C
Ann Otol Rhinol Laryngol 1996 Jan;105(1):75-82. doi: 10.1177/000348949610500115. PMID: 8546432

Clinical prediction guides

Prevalence of Synchronous ESCN in Head and Neck Cancer: A Single-Institution Perspective.
Thakur K, Singh CA, Thakar A, Kakkar A, Sikka K, Kumar R, Sharma SC
Laryngoscope 2021 Mar;131(3):E807-E814. Epub 2020 Jul 3 doi: 10.1002/lary.28821. PMID: 32619324
P16 detection in benign, precursor epithelial lesions and carcinomas of head and neck.
Chatzipantelis P, Koukourakis M, Kouroupi M, Giatromanolaki A
Pathol Res Pract 2020 Aug;216(8):153035. Epub 2020 Jun 13 doi: 10.1016/j.prp.2020.153035. PMID: 32703498
Role of narrow-band imaging in detection of head and neck unknown primary squamous cell carcinoma.
Filauro M, Paderno A, Perotti P, Marchi F, Garofolo S, Peretti G, Piazza C
Laryngoscope 2018 Sep;128(9):2060-2066. Epub 2018 Feb 2 doi: 10.1002/lary.27098. PMID: 29392723
Short-term postoperative distress associated with open vs. transoral robotic surgery (TORS) in patients with T1-T2 carcinomas of the tongue base and supraglottis.
Slama K, Slouka D, Slipka J, Fischer S
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2016 Sep;160(3):423-8. Epub 2016 Mar 17 doi: 10.5507/bp.2016.015. PMID: 26996243
Type of alcoholic beverage and cancer of the upper respiratory and digestive tract.
Leclerc A, Brugère J, Luce D, Point D, Guenel P
Eur J Cancer Clin Oncol 1987 May;23(5):529-34. doi: 10.1016/0277-5379(87)90315-4. PMID: 3653176

Recent systematic reviews

Epidemiological, clinical and oncological outcomes of laryngeal verrucous carcinomas: a systematic review.
Lechien JR, Hans S
J Otolaryngol Head Neck Surg 2023 Dec 13;52(1):81. doi: 10.1186/s40463-023-00666-1. PMID: 38093339Free PMC Article
Epidemiological, clinical and oncological outcomes of young patients with laryngeal cancer: a systematic review.
Lechien JR, Maniaci A, Hans S, Iannella G, Fakhry N, Mayo-Yáñez M, Ayad T, Mannelli G, Chiesa-Estomba CM
Eur Arch Otorhinolaryngol 2022 Dec;279(12):5741-5753. Epub 2022 Jun 2 doi: 10.1007/s00405-022-07466-9. PMID: 35652941
Diagnostic value of sentinel lymph node biopsy in head and neck cancer: a meta-analysis.
Thompson CF, St John MA, Lawson G, Grogan T, Elashoff D, Mendelsohn AH
Eur Arch Otorhinolaryngol 2013 Jul;270(7):2115-22. Epub 2012 Dec 22 doi: 10.1007/s00405-012-2320-0. PMID: 23263205Free PMC Article
Basaloid squamous cell carcinoma of the larynx--A systematic review.
Thankappan K
Auris Nasus Larynx 2012 Aug;39(4):397-401. Epub 2011 Aug 24 doi: 10.1016/j.anl.2011.07.018. PMID: 21868181

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...