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Male Non-Neoplastic Reproductive System Disorder

MedGen UID:: 277325
•Concept ID:: C1334554
•: Disease or Syndrome

Synonym:

Male Non-Neoplastic Reproductive System Disease

Definition

A non-neoplastic disorder that affects the male reproductive system. Representative examples include prostatitis, balanitis, and phimosis. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMale Non-Neoplastic Reproductive System Disorder

Pathological process
- Disease
  - Disorder by Site
    - Disorder of the genitourinary system
      - Reproductive system disorder
        Male reproductive system disorder
        Male Non-Neoplastic Reproductive System Disorder
        Disorder of ejaculation
        Erectile dysfunction
        Autonomic erectile dysfunction
        Impotence
        Priapism
        Vasculogenic impotence
        Penile Non-Neoplastic Disorder
        Balanitis
        Balanitis xerotica obliterans
        Leukoplakia of penis
        Hypospadias
        Coronal hypospadias
        Glandular hypospadias
        Midshaft hypospadias
        Penile hypospadias
        Penoscrotal hypospadias
        Perineal hypospadias
        Scrotal hypospadias
        Paraphimosis
        Penile Chordee
        Tight foreskin
        Phimosis
        Prostate Non-Neoplastic Disorder
        Enlarged Prostate with Lower Urinary Tract Symptoms
        Prostatic Infection
        Bacterial prostatitis
        Trichomonas prostatitis
        Prostatitis
        Acute prostatitis
        Asymptomatic Inflammatory Prostatitis
        Chronic prostatitis
        Granulomatous prostatitis
        Testicular Non-Neoplastic Disorder
        Ascending Testicle
        Cryptorchidism
        Bilateral cryptorchidism
        Unilateral cryptorchidism
        Orchitis
        Non-specific granulomatous orchitis
        Retractile testis
        Spermatic cord torsion
        Testicular atrophy
        Testicular Hypotrophy
        Testicular infarct

Professional guidelines

PubMed

Long-term complications of lymphoma and its treatment.

Ng AK, LaCasce A, Travis LB
J Clin Oncol 2011 May 10;29(14):1885-92. Epub 2011 Apr 11 doi: 10.1200/JCO.2010.32.8427. PMID: 21483015

See all (1)

Recent clinical studies

Etiology

Garolla A, Graziani A, Grande G, Ortolani C, Ferlin A
J Endocrinol Invest 2024 Feb;47(2):261-274. Epub 2023 Sep 28 doi: 10.1007/s40618-023-02192-3. PMID: 37770654 Free PMC Article

Immunoexpression of HSPA9 and CUL2 in prostatic tissue and adenocarcinoma.

Hirth CG, Vasconcelos GR, da Cunha MDPSS, Leite CHB, Dornelas CA
Ann Diagn Pathol 2022 Feb;56:151843. Epub 2021 Oct 20 doi: 10.1016/j.anndiagpath.2021.151843. PMID: 34717191

Gonadoblastoma: origin and outcome.

Roth LM, Cheng L
Hum Pathol 2020 Jun;100:47-53. Epub 2019 Dec 2 doi: 10.1016/j.humpath.2019.11.005. PMID: 31805291

Long-term complications of lymphoma and its treatment.

Ng AK, LaCasce A, Travis LB
J Clin Oncol 2011 May 10;29(14):1885-92. Epub 2011 Apr 11 doi: 10.1200/JCO.2010.32.8427. PMID: 21483015

Tumors of the testis in intersex syndromes.

Levin HS
Urol Clin North Am 2000 Aug;27(3):543-51, x. doi: 10.1016/s0094-0143(05)70101-4. PMID: 10985153

See all (18)

Diagnosis

Use of contrast enhanced ultrasound in testicular diseases: A comprehensive review.

Tenuta M, Sesti F, Bonaventura I, Mazzotta P, Pofi R, Gianfrilli D, Pozza C
Andrology 2021 Sep;9(5):1369-1382. Epub 2021 Jun 11 doi: 10.1111/andr.13057. PMID: 34043256 Free PMC Article

Neurologic disorders associated with disease of the ovaries and testis.

Kattah JC, Kattah WC
Handb Clin Neurol 2014;120:787-98. doi: 10.1016/B978-0-7020-4087-0.00052-8. PMID: 24365352

Paratesticular tumor-like lesions.

Oliva E, Young RH
Semin Diagn Pathol 2000 Nov;17(4):340-58. PMID: 11202549

Tumors of the testis in intersex syndromes.

Levin HS
Urol Clin North Am 2000 Aug;27(3):543-51, x. doi: 10.1016/s0094-0143(05)70101-4. PMID: 10985153

"Mesenchymal tumor" or "decidual-like reaction"?

Karbe E
Toxicol Pathol 1999 May-Jun;27(3):354-62. doi: 10.1177/019262339902700312. PMID: 10356713

See all (15)

Therapy

Garolla A, Graziani A, Grande G, Ortolani C, Ferlin A
J Endocrinol Invest 2024 Feb;47(2):261-274. Epub 2023 Sep 28 doi: 10.1007/s40618-023-02192-3. PMID: 37770654 Free PMC Article

Lymphatic Vascularization in Prostate Adenocarcinoma: Correlation with Tumor Grade, Androgen Withdrawal and Prognosis.

Ambrosio MR, Rocca BJ, Barone A, Ginori A, Crivelli F, Pirtoli L, Del Vecchio MT
Anticancer Res 2015 Oct;35(10):5595-600. PMID: 26408731

Prostate tissue metal levels and prostate cancer recurrence in smokers.

Neslund-Dudas C, Kandegedara A, Kryvenko ON, Gupta N, Rogers C, Rybicki BA, Dou QP, Mitra B
Biol Trace Elem Res 2014 Feb;157(2):107-12. Epub 2014 Jan 4 doi: 10.1007/s12011-013-9874-6. PMID: 24385087 Free PMC Article

Long-term complications of lymphoma and its treatment.

Ng AK, LaCasce A, Travis LB
J Clin Oncol 2011 May 10;29(14):1885-92. Epub 2011 Apr 11 doi: 10.1200/JCO.2010.32.8427. PMID: 21483015

Neoadjuvant hormonal deprivation before radical prostatectomy.

Schulman CC, Sassine AM
Clin Invest Med 1993 Dec;16(6):523-31. PMID: 7516836

See all (5)

Prognosis

Immunoexpression of HSPA9 and CUL2 in prostatic tissue and adenocarcinoma.

Hirth CG, Vasconcelos GR, da Cunha MDPSS, Leite CHB, Dornelas CA
Ann Diagn Pathol 2022 Feb;56:151843. Epub 2021 Oct 20 doi: 10.1016/j.anndiagpath.2021.151843. PMID: 34717191

Use of contrast enhanced ultrasound in testicular diseases: A comprehensive review.

Tenuta M, Sesti F, Bonaventura I, Mazzotta P, Pofi R, Gianfrilli D, Pozza C
Andrology 2021 Sep;9(5):1369-1382. Epub 2021 Jun 11 doi: 10.1111/andr.13057. PMID: 34043256 Free PMC Article

Immunohistochemistry of immune checkpoint markers PD-1 and PD-L1 in prostate cancer.

Sharma M, Yang Z, Miyamoto H
Medicine (Baltimore) 2019 Sep;98(38):e17257. doi: 10.1097/MD.0000000000017257. PMID: 31567999 Free PMC Article

Long-term complications of lymphoma and its treatment.

Ng AK, LaCasce A, Travis LB
J Clin Oncol 2011 May 10;29(14):1885-92. Epub 2011 Apr 11 doi: 10.1200/JCO.2010.32.8427. PMID: 21483015

High levels of phosphorylated form of Akt-1 in prostate cancer and non-neoplastic prostate tissues are strong predictors of biochemical recurrence.

Ayala G, Thompson T, Yang G, Frolov A, Li R, Scardino P, Ohori M, Wheeler T, Harper W
Clin Cancer Res 2004 Oct 1;10(19):6572-8. doi: 10.1158/1078-0432.CCR-04-0477. PMID: 15475446

See all (11)

Clinical prediction guides

Garolla A, Graziani A, Grande G, Ortolani C, Ferlin A
J Endocrinol Invest 2024 Feb;47(2):261-274. Epub 2023 Sep 28 doi: 10.1007/s40618-023-02192-3. PMID: 37770654 Free PMC Article

Immunoexpression of HSPA9 and CUL2 in prostatic tissue and adenocarcinoma.

Hirth CG, Vasconcelos GR, da Cunha MDPSS, Leite CHB, Dornelas CA
Ann Diagn Pathol 2022 Feb;56:151843. Epub 2021 Oct 20 doi: 10.1016/j.anndiagpath.2021.151843. PMID: 34717191

Use of contrast enhanced ultrasound in testicular diseases: A comprehensive review.

Tenuta M, Sesti F, Bonaventura I, Mazzotta P, Pofi R, Gianfrilli D, Pozza C
Andrology 2021 Sep;9(5):1369-1382. Epub 2021 Jun 11 doi: 10.1111/andr.13057. PMID: 34043256 Free PMC Article

Long-term complications of lymphoma and its treatment.

Ng AK, LaCasce A, Travis LB
J Clin Oncol 2011 May 10;29(14):1885-92. Epub 2011 Apr 11 doi: 10.1200/JCO.2010.32.8427. PMID: 21483015

"Mesenchymal tumor" or "decidual-like reaction"?

Karbe E
Toxicol Pathol 1999 May-Jun;27(3):354-62. doi: 10.1177/019262339902700312. PMID: 10356713

See all (13)

MedGen

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Male Non-Neoplastic Reproductive System Disorder

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Supplemental Content

Table of contents

Practice guidelines

Recent activity