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Capsular Invasion

MedGen UID:
310581
•Concept ID:
C1707265
•
Finding

Definition

A microscopic finding indicating the infiltration of the capsule that surrounds an organ by a malignant cellular population. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCapsular Invasion

Professional guidelines

PubMed

Deep Learning-Based Differential Diagnosis of Follicular Thyroid Tumors Using Histopathological Images.
Nojima S, Kadoi T, Suzuki A, Kato C, Ishida S, Kido K, Fujita K, Okuno Y, Hirokawa M, Terayama K, Morii E
Mod Pathol 2023 Nov;36(11):100296. Epub 2023 Jul 31 doi: 10.1016/j.modpat.2023.100296. PMID: 37532181
Differential diagnosis of non-diffuse primary thyroid lymphoma and papillary thyroid carcinoma by ultrasound combined with computed tomography.
Peng C, Yi D, Zhou Y, Yao J, Chen B, Yang C, Xu D
BMC Cancer 2022 Aug 31;22(1):938. doi: 10.1186/s12885-022-10035-2. PMID: 36042430Free PMC Article
Invasion in thyroid cancer: Controversies and best practices.
Nishino M, Jacob J
Semin Diagn Pathol 2020 Sep;37(5):219-227. Epub 2020 Mar 4 doi: 10.1053/j.semdp.2020.02.003. PMID: 32173146

Recent clinical studies

Etiology

Microwave Ablation for Papillary Thyroid Microcarcinoma with and without US-detected Capsule Invasion: A Multicenter Prospective Cohort Study.
Zheng L, Dou JP, Han ZY, Liu FY, Yu J, Cheng ZG, Yu XL, Wang H, Cong ZB, Wang SR, Yu MA, Xu ZF, Che Y, Nan B, Liu C, Hao Y, Wang X, Liu Y, Zhou Y, Liang P
Radiology 2023 May;307(3):e220661. Epub 2023 Mar 7 doi: 10.1148/radiol.220661. PMID: 36880949
Breast Implant Capsule-Associated Squamous Cell Carcinoma: Report of 2 Patients.
Whaley RD, Aldrees R, Dougherty RE, Prieto Granada C, Badve SS, Al Diffalha S
Int J Surg Pathol 2022 Dec;30(8):900-907. Epub 2022 Mar 18 doi: 10.1177/10668969221086940. PMID: 35300538
Risk Factors for Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.
Mao J, Zhang Q, Zhang H, Zheng K, Wang R, Wang G
Front Endocrinol (Lausanne) 2020;11:265. Epub 2020 May 15 doi: 10.3389/fendo.2020.00265. PMID: 32477264Free PMC Article
Noninvasive follicular thyroid neoplasm with papillary-like nuclear features.
Ghuzlan AA, Ramos HE, Schlumberger M
Curr Opin Endocrinol Diabetes Obes 2017 Oct;24(5):377-380. doi: 10.1097/MED.0000000000000358. PMID: 28678083
Follicular neoplasms of the thyroid: what to recommend.
Carling T, Udelsman R
Thyroid 2005 Jun;15(6):583-7. doi: 10.1089/thy.2005.15.583. PMID: 16029125

Diagnosis

Risk factors for central lymph node metastasis in patients with papillary thyroid carcinoma: a retrospective study.
Du J, Yang Q, Sun Y, Shi P, Xu H, Chen X, Dong T, Shi W, Wang Y, Song Z, Shang X, Tian X
Front Endocrinol (Lausanne) 2023;14:1288527. Epub 2023 Nov 17 doi: 10.3389/fendo.2023.1288527. PMID: 38047112Free PMC Article
A case report of solitary fibrous tumor of the thyroid gland and literature review.
Zhang J, Han S, Zhao Y, Song P, Zhang H, Zhang J, Ding D, Wu Y
Medicine (Baltimore) 2023 Aug 25;102(34):e34710. doi: 10.1097/MD.0000000000034710. PMID: 37653837Free PMC Article
FAMILIAL NON-MEDULLARY THYROID CARCINOMA.
Guda BB, Komisarenko II, Ostafiichuk MV, Tronko MD
Exp Oncol 2023 Jun 26;45(1):70-78. doi: 10.15407/exp-oncology.2023.01.070. PMID: 37417280
MEG3 Expression Indicates Lymph Node Metastasis and Presence of Cancer-Associated Fibroblasts in Papillary Thyroid Cancer.
Dadafarin S, Rodríguez TC, Carnazza MA, Tiwari RK, Moscatello A, Geliebter J
Cells 2022 Oct 10;11(19) doi: 10.3390/cells11193181. PMID: 36231143Free PMC Article
A Woman with Normotensive Primary Hyperaldosteronism.
Moradi S, Shafiepour M, Amirbaigloo A
Acta Med Iran 2016 Feb;54(2):156-8. PMID: 26997605

Therapy

Machine learning based on SEER database to predict distant metastasis of thyroid cancer.
Qiao L, Li H, Wang Z, Sun H, Feng G, Yin D
Endocrine 2024 Jun;84(3):1040-1050. Epub 2023 Dec 29 doi: 10.1007/s12020-023-03657-4. PMID: 38155324
Microwave Ablation for Papillary Thyroid Microcarcinoma with and without US-detected Capsule Invasion: A Multicenter Prospective Cohort Study.
Zheng L, Dou JP, Han ZY, Liu FY, Yu J, Cheng ZG, Yu XL, Wang H, Cong ZB, Wang SR, Yu MA, Xu ZF, Che Y, Nan B, Liu C, Hao Y, Wang X, Liu Y, Zhou Y, Liang P
Radiology 2023 May;307(3):e220661. Epub 2023 Mar 7 doi: 10.1148/radiol.220661. PMID: 36880949
Breast Implant Capsule-Associated Squamous Cell Carcinoma: Report of 2 Patients.
Whaley RD, Aldrees R, Dougherty RE, Prieto Granada C, Badve SS, Al Diffalha S
Int J Surg Pathol 2022 Dec;30(8):900-907. Epub 2022 Mar 18 doi: 10.1177/10668969221086940. PMID: 35300538
Lymph node status influences follow-up thyroglobulin levels in papillary thyroid cancer.
Low TH, Delbridge L, Sidhu S, Learoyd D, Robinson B, Roach P, Sywak M
Ann Surg Oncol 2008 Oct;15(10):2827-32. Epub 2008 Jul 18 doi: 10.1245/s10434-008-0049-1. PMID: 18636294
Thyroglossal duct carcinoma in children: case presentation and review of the literature.
Peretz A, Leiberman E, Kapelushnik J, Hershkovitz E
Thyroid 2004 Sep;14(9):777-85. doi: 10.1089/thy.2004.14.777. PMID: 15361266

Prognosis

Risk factors for central lymph node metastasis in patients with papillary thyroid carcinoma: a retrospective study.
Du J, Yang Q, Sun Y, Shi P, Xu H, Chen X, Dong T, Shi W, Wang Y, Song Z, Shang X, Tian X
Front Endocrinol (Lausanne) 2023;14:1288527. Epub 2023 Nov 17 doi: 10.3389/fendo.2023.1288527. PMID: 38047112Free PMC Article
Breast Implant Capsule-Associated Squamous Cell Carcinoma: Report of 2 Patients.
Whaley RD, Aldrees R, Dougherty RE, Prieto Granada C, Badve SS, Al Diffalha S
Int J Surg Pathol 2022 Dec;30(8):900-907. Epub 2022 Mar 18 doi: 10.1177/10668969221086940. PMID: 35300538
Risk Factors for Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.
Mao J, Zhang Q, Zhang H, Zheng K, Wang R, Wang G
Front Endocrinol (Lausanne) 2020;11:265. Epub 2020 May 15 doi: 10.3389/fendo.2020.00265. PMID: 32477264Free PMC Article
A Woman with Normotensive Primary Hyperaldosteronism.
Moradi S, Shafiepour M, Amirbaigloo A
Acta Med Iran 2016 Feb;54(2):156-8. PMID: 26997605
Chondrosarcoma of the hyoid bone.
Itoh K, Nobori T, Fukuda K, Furuta S, Ohyama M
J Laryngol Otol 1993 Jul;107(7):642-6. doi: 10.1017/s0022215100123977. PMID: 15125291

Clinical prediction guides

Risk factors for central lymph node metastasis in patients with papillary thyroid carcinoma: a retrospective study.
Du J, Yang Q, Sun Y, Shi P, Xu H, Chen X, Dong T, Shi W, Wang Y, Song Z, Shang X, Tian X
Front Endocrinol (Lausanne) 2023;14:1288527. Epub 2023 Nov 17 doi: 10.3389/fendo.2023.1288527. PMID: 38047112Free PMC Article
Microwave Ablation for Papillary Thyroid Microcarcinoma with and without US-detected Capsule Invasion: A Multicenter Prospective Cohort Study.
Zheng L, Dou JP, Han ZY, Liu FY, Yu J, Cheng ZG, Yu XL, Wang H, Cong ZB, Wang SR, Yu MA, Xu ZF, Che Y, Nan B, Liu C, Hao Y, Wang X, Liu Y, Zhou Y, Liang P
Radiology 2023 May;307(3):e220661. Epub 2023 Mar 7 doi: 10.1148/radiol.220661. PMID: 36880949
MEG3 Expression Indicates Lymph Node Metastasis and Presence of Cancer-Associated Fibroblasts in Papillary Thyroid Cancer.
Dadafarin S, Rodríguez TC, Carnazza MA, Tiwari RK, Moscatello A, Geliebter J
Cells 2022 Oct 10;11(19) doi: 10.3390/cells11193181. PMID: 36231143Free PMC Article
Risk Factors for Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.
Mao J, Zhang Q, Zhang H, Zheng K, Wang R, Wang G
Front Endocrinol (Lausanne) 2020;11:265. Epub 2020 May 15 doi: 10.3389/fendo.2020.00265. PMID: 32477264Free PMC Article
Follicular thyroid lesions, elements that affect both diagnosis and prognosis.
Zeiger MA, Dackiw AP
J Surg Oncol 2005 Mar 1;89(3):108-13. doi: 10.1002/jso.20186. PMID: 15719377

Recent systematic reviews

Risk factors for cervical lymph node metastasis in the central or lateral cervical region in medullary thyroid carcinoma: a systematic review and meta-analysis.
Lin X, Huo J, Su H, Zhu C, Xu Y, Zhang F
Eur Arch Otorhinolaryngol 2024 Feb;281(2):547-561. Epub 2023 Oct 6 doi: 10.1007/s00405-023-08249-6. PMID: 37801162
The risk of central nodal metastasis based on prognostic factors of the differentiated thyroid carcinoma: a systematic review and meta-analysis study.
Hafez LG, Elkomos BE, El-Shafaei MAM, Omran HMA, Saad AS
Eur Arch Otorhinolaryngol 2023 Jun;280(6):2675-2686. Epub 2023 Feb 10 doi: 10.1007/s00405-023-07863-8. PMID: 36759363Free PMC Article
Risk Factors for Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.
Mao J, Zhang Q, Zhang H, Zheng K, Wang R, Wang G
Front Endocrinol (Lausanne) 2020;11:265. Epub 2020 May 15 doi: 10.3389/fendo.2020.00265. PMID: 32477264Free PMC Article
Risk Factors for Central Lymph Node Metastasis in CN0 Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.
Sun W, Lan X, Zhang H, Dong W, Wang Z, He L, Zhang T, Liu S
PLoS One 2015;10(10):e0139021. Epub 2015 Oct 2 doi: 10.1371/journal.pone.0139021. PMID: 26431346Free PMC Article
Clinical risk factors for central lymph node metastasis in papillary thyroid carcinoma: a systematic review and meta-analysis.
Qu H, Sun GR, Liu Y, He QS
Clin Endocrinol (Oxf) 2015 Jul;83(1):124-32. Epub 2014 Sep 22 doi: 10.1111/cen.12583. PMID: 25130203

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