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Rectal adenosquamous carcinoma

MedGen UID:
313658
•Concept ID:
C1709865
•
Neoplastic Process
Synonyms: rectal adenosquamous cancer; Rectal Adenosquamous Carcinoma; rectal adenosquamous carcinoma
 
Monarch Initiative: MONDO:0056817

Definition

An unusual rectal carcinoma characterized by the presence of glandular and squamous carcinomatous components. The two carcinomatous components may be admixed within the tumor, or the two may appear separately in different areas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRectal adenosquamous carcinoma

Professional guidelines

PubMed

Presentation, treatment, and prognosis of colorectal adenosquamous carcinoma: A contemporary analysis of the surveillance, epidemiology, and end results database.
Khan AH, Gao X, Goffredo P, Kahl AR, Utria AF, Charlton ME, Ahad S, Hassan I
Am J Surg 2022 May;223(5):957-962. Epub 2021 Sep 11 doi: 10.1016/j.amjsurg.2021.09.004. PMID: 34530984
Combined external and intracavitary irradiation in treatment of advanced cervical carcinomas: predictive factors for treatment outcome and early and late radiation reactions.
Bohr Mordhorst L, Karlsson L, Bärmark B, Sorbe B
Int J Gynecol Cancer 2014 Sep;24(7):1268-75. doi: 10.1097/IGC.0000000000000208. PMID: 25078336
High-dose-rate intracavitary brachytherapy (HDR-IC) in treatment of cervical carcinoma: 5-year results and implication of increased low-grade rectal complication on initiation of an HDR-IC fractionation scheme.
Wang CJ, Leung SW, Chen HC, Sun LM, Fang FM, Changchien CC, Huang EY, Wu JM, Chen CC
Int J Radiat Oncol Biol Phys 1997 May 1;38(2):391-8. doi: 10.1016/s0360-3016(96)00624-4. PMID: 9226328

Recent clinical studies

Etiology

Characteristics of anal canal cancer in Japan.
Yamada K, Saiki Y, Komori K, Shiomi A, Ueno M, Ito M, Hida K, Yamamoto S, Shiozawa M, Ishihara S, Kanemitsu Y, Ueno H, Kinjo T, Maeda K, Kawamura J, Fujita F, Takahashi K, Mizushima T, Shimada Y, Sasaki S, Sunami E, Ishida F, Hirata K, Ohnuma S, Funahashi K, Watanabe J, Kinugasa Y, Yamaguchi S, Hashiguchi Y, Ikeda M, Sudo T, Komatsu Y, Koda K, Sakamoto K, Okajima M, Ishida H, Hisamatsu Y, Masuda T, Mori S, Minami K, Hasegawa S, Endo S, Iwashita A, Hamada M, Ajioka Y, Usuku K, Ikeda T, Sugihara K
Cancer Med 2022 Jul;11(14):2735-2743. Epub 2022 Mar 10 doi: 10.1002/cam4.4631. PMID: 35274487Free PMC Article
Cervical Cancer Staging in Saudi Arabia Clinicoradiological Correlation.
Anfinan N
Biomed Res Int 2019;2019:8745828. Epub 2019 Jun 23 doi: 10.1155/2019/8745828. PMID: 31341909Free PMC Article
Population-based evaluation of adenosquamous carcinoma of the colon and rectum.
Masoomi H, Ziogas A, Lin BS, Barleben A, Mills S, Stamos MJ, Zell JA
Dis Colon Rectum 2012 May;55(5):509-14. doi: 10.1097/DCR.0b013e3182420953. PMID: 22513428Free PMC Article
Adenosquamous and squamous carcinoma of the colon and upper rectum: a clinical and histopathologic study.
Frizelle FA, Hobday KS, Batts KP, Nelson H
Dis Colon Rectum 2001 Mar;44(3):341-6. doi: 10.1007/BF02234730. PMID: 11289278
Adenosquamous carcinoma of the colon and rectum.
Petrelli NJ, Valle AA, Weber TK, Rodriguez-Bigas M
Dis Colon Rectum 1996 Nov;39(11):1265-8. doi: 10.1007/BF02055120. PMID: 8918436

Diagnosis

Presentation, treatment, and prognosis of colorectal adenosquamous carcinoma: A contemporary analysis of the surveillance, epidemiology, and end results database.
Khan AH, Gao X, Goffredo P, Kahl AR, Utria AF, Charlton ME, Ahad S, Hassan I
Am J Surg 2022 May;223(5):957-962. Epub 2021 Sep 11 doi: 10.1016/j.amjsurg.2021.09.004. PMID: 34530984
Genetic Diagnosis of an Adenosquamous Cell Carcinoma of the Rectum in a 12-Year-Old Child.
Martinez Redondo I, Vera Sáez-Benito MC, Martinez Faci C, Murillo Sanjuan L, Rodriguez-Vigil Iturrate C, Calvo Escribano MA, Carboné Bañeres AI
J Pediatr Hematol Oncol 2017 Jan;39(1):79. doi: 10.1097/MPH.0000000000000678. PMID: 27820123
Primary adenosquamous carcinoma of the prostate: a rare aggressive tumor.
Mishra S, Goel H, Awasthi N, Puri A, Mahapatra R, Pal DK
Clin Genitourin Cancer 2014 Feb;12(1):e29-31. Epub 2013 Oct 19 doi: 10.1016/j.clgc.2013.08.006. PMID: 24145000
Population-based evaluation of adenosquamous carcinoma of the colon and rectum.
Masoomi H, Ziogas A, Lin BS, Barleben A, Mills S, Stamos MJ, Zell JA
Dis Colon Rectum 2012 May;55(5):509-14. doi: 10.1097/DCR.0b013e3182420953. PMID: 22513428Free PMC Article
Primary adenosquamous and squamous cell carcinoma of the colon and rectum.
Schneider TA 2nd, Birkett DH, Vernava AM 3rd
Int J Colorectal Dis 1992 Sep;7(3):144-7. doi: 10.1007/BF00360355. PMID: 1402312

Therapy

Outcomes analysis of pre-brachytherapy MRI in patients with locally advanced cervical cancer.
Murofushi K, Yoshioka Y, Sumi M, Ishikawa H, Oguchi M, Sakurai H
Int J Gynecol Cancer 2020 Apr;30(4):473-479. Epub 2020 Mar 11 doi: 10.1136/ijgc-2019-000925. PMID: 32165406
Toxicities and dose-volume histogram parameters of MRI-based brachytherapy for cervical cancer.
Kim Y, Kim YJ, Kim JY, Lim YK, Jeong C, Jeong J, Kim M, Lim MC, Seo SS, Park SY
Brachytherapy 2017 Jan-Feb;16(1):116-125. Epub 2016 Nov 18 doi: 10.1016/j.brachy.2016.10.005. PMID: 27876378
Genetic Diagnosis of an Adenosquamous Cell Carcinoma of the Rectum in a 12-Year-Old Child.
Martinez Redondo I, Vera Sáez-Benito MC, Martinez Faci C, Murillo Sanjuan L, Rodriguez-Vigil Iturrate C, Calvo Escribano MA, Carboné Bañeres AI
J Pediatr Hematol Oncol 2017 Jan;39(1):79. doi: 10.1097/MPH.0000000000000678. PMID: 27820123
Adenosquamous Cell Carcinoma of the Rectum in a Girl: First Case Reported and Review of the Literature.
García NÁ, Hernando Cubero J, Alonso Orduña V, Torrecilla Idoipe N, Calvo Escribano C, Fernandez Atuán R
J Pediatr Hematol Oncol 2015 Aug;37(6):e364-7. doi: 10.1097/MPH.0000000000000361. PMID: 26181422
Adenosquamous carcinoma of the rectum showing endocrine-cell differentiation: report of a case.
Kono T, Yamamoto Y, Kakisaka A, Tokusasi Y, Miyokawa N, Kasai S
Dis Colon Rectum 1999 Aug;42(8):1089-92. doi: 10.1007/BF02236710. PMID: 10458137

Prognosis

Presentation, treatment, and prognosis of colorectal adenosquamous carcinoma: A contemporary analysis of the surveillance, epidemiology, and end results database.
Khan AH, Gao X, Goffredo P, Kahl AR, Utria AF, Charlton ME, Ahad S, Hassan I
Am J Surg 2022 May;223(5):957-962. Epub 2021 Sep 11 doi: 10.1016/j.amjsurg.2021.09.004. PMID: 34530984
Genetic Diagnosis of an Adenosquamous Cell Carcinoma of the Rectum in a 12-Year-Old Child.
Martinez Redondo I, Vera Sáez-Benito MC, Martinez Faci C, Murillo Sanjuan L, Rodriguez-Vigil Iturrate C, Calvo Escribano MA, Carboné Bañeres AI
J Pediatr Hematol Oncol 2017 Jan;39(1):79. doi: 10.1097/MPH.0000000000000678. PMID: 27820123
Primary adenosquamous carcinoma of the prostate: a rare aggressive tumor.
Mishra S, Goel H, Awasthi N, Puri A, Mahapatra R, Pal DK
Clin Genitourin Cancer 2014 Feb;12(1):e29-31. Epub 2013 Oct 19 doi: 10.1016/j.clgc.2013.08.006. PMID: 24145000
Population-based evaluation of adenosquamous carcinoma of the colon and rectum.
Masoomi H, Ziogas A, Lin BS, Barleben A, Mills S, Stamos MJ, Zell JA
Dis Colon Rectum 2012 May;55(5):509-14. doi: 10.1097/DCR.0b013e3182420953. PMID: 22513428Free PMC Article
Adenosquamous and squamous carcinoma of the colon and upper rectum: a clinical and histopathologic study.
Frizelle FA, Hobday KS, Batts KP, Nelson H
Dis Colon Rectum 2001 Mar;44(3):341-6. doi: 10.1007/BF02234730. PMID: 11289278

Clinical prediction guides

Colonic adenosquamous carcinoma and mucinous adenocarcinoma with microsatellite instability.
Parra-Medina R, Lopez-Correa P, Gutierrez V, Polo F
Malays J Pathol 2018 Aug;40(2):199-202. PMID: 30173239
Toxicities and dose-volume histogram parameters of MRI-based brachytherapy for cervical cancer.
Kim Y, Kim YJ, Kim JY, Lim YK, Jeong C, Jeong J, Kim M, Lim MC, Seo SS, Park SY
Brachytherapy 2017 Jan-Feb;16(1):116-125. Epub 2016 Nov 18 doi: 10.1016/j.brachy.2016.10.005. PMID: 27876378
Adenosquamous Cell Carcinoma of the Rectum in a Girl: First Case Reported and Review of the Literature.
García NÁ, Hernando Cubero J, Alonso Orduña V, Torrecilla Idoipe N, Calvo Escribano C, Fernandez Atuán R
J Pediatr Hematol Oncol 2015 Aug;37(6):e364-7. doi: 10.1097/MPH.0000000000000361. PMID: 26181422
Safety of hepatic resection in metastatic disease to the liver after yttrium-90 therapy.
Whitney R, Tatum C, Hahl M, Ellis S, Scoggins CR, McMasters K, Martin RC
J Surg Res 2011 Apr;166(2):236-40. Epub 2009 Jun 12 doi: 10.1016/j.jss.2009.05.021. PMID: 19691985
Squamous metaplasia in colorectal polyps.
Almagro UA, Pintar K, Zellmer RB
Cancer 1984 Jun 15;53(12):2679-82. doi: 10.1002/1097-0142(19840615)53:12<2679::aid-cncr2820531219>3.0.co;2-6. PMID: 6722726

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